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Elsevier

Academic Press

  • Advances in Technology-Assisted Neurorehabilitation

    • 1st Edition
    • Natalia M. López
    • English
    Advances in Technology-Assisted Neurorehabilitation introduces biomedical engineers, health professionals and researchers to the study and integration of neurorehabilitation advances, specifically focusing on applied technologies and mathematical methods. Coverage includes neuromodulation, robotic rehabilitation devices, signal processing, human-machine interfaces, software development, serious games and virtual reality. It takes an interdisciplinary approach, including real world applications and new trends. Both medical and technological fields are represented, with a focus on neurological disease. With the computerization of today's therapeutic technology, this book is a valuable asset to any student in the bioengineering or healthcare fields.

  • The Immunology of the Domestic Ruminants

    Cattle, Sheep, and Goats
    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of Domestic Ruminants: Cattle, Sheep, and Goats provides a thorough examination of the immune systems of these animals. It explores their normal immune functions and their roles in combating infectious and parasitic diseases, chronic inflammatory conditions, and immunodeficiency disorders. The book incorporates new data from the bovine genome project and highlights significant breed differences. Both innate and adaptive immunity are systematically covered, offering insights into basic and applied aspects of bovine immunology. In addition to detailing the immunology of major bacterial, viral, and parasitic diseases in cattle, the book reviews bovine vaccines and emphasizes the importance nutrition.This essential resource caters to professionals in large animal research and practice, providing comprehensive information on the immunology of domestic cattle, sheep, and goats.

  • Cholecystokinin

    From Gallbladder to Cognition and Beyond
    • 1st Edition
    • Christine Feinle-Bisset + 1 more
    • English
    Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function.Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.

  • Methods for Monitoring Mitochondrial Functions During Pathogen Infection

    • 1st Edition
    • Volume 194
    • English
    Methods for Monitoring Mitochondrial Functions During Pathogen Infection, Volume 194 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Mitochondrial Labeling with Fluorescent Proteins for Enhanced Morphological Characterization and Visualization of Intercellular Mitochondrial Transfer, Visualizing mitochondrial electron transport chain complexes and super-complexes during infection of human macrophages with Legionella pneumophila, Quantitative assessment of mitochondrial membrane potential in macrophages in sepsis, Quantification of mitochondrial reactive oxygen species in macrophages during sepsis, and much more.Additional chapters cover Quantification of intracellular and mitochondrial ATP content in macrophages during lipopolysaccharide-i... inflammatory response, Analysis of cytosolic mtDNA release during Staphylococcus Aureus infection, Monitoring mitochondria dynamics upon infection using a tomographic approach, A screening system to determine bacterial effects on MADCAM1 expression by high endothelial venule cells, Isolation of mitochondria from Mycobacteria infected cells, Monitoring mitochondrial localization of Mycobacterial proteins, and more.

  • Near-boundary Fluid Mechanics

    • 1st Edition
    • Shu-Qing Yang
    • English
    Near-Boundary Fluid Mechanics focuses on the near-boundary region and its significance. It delves into topics like boundary shear stress, drag reduction using polymer additives, turbulence sources, secondary currents, log-law validity, sediment transport, and more. Unlike similar books, it emphasizes the importance of the near-boundary region. This book is organized into chapters covering internal flows, external flows, loose boundary flows, and density currents. It extends Prandtl's fundamental concept to internal flows, showing how potential flow theory can describe flow without a solid boundary.In addition, the book provides a theoretical analysis of boundary shear stress in three-dimensional flows and explores the turbulent structures in drag-reduction flows. A key feature is clarifying the role of wall-normal velocity in mass, moment, and energy transfer. Additionally, Archimedes' principle is covered to explain pressure drag and establishes a relationship between wake volume and hydrodynamic force.

  • Challenges in Delivery of Therapeutic Genomics and Proteomics

    • 2nd Edition
    • Aliasgar Shahiwala + 1 more
    • English
    Challenges in Delivery of Therapeutic Genomics and Proteomics, Second Edition is a complete reference on the biological principles involved in gene and protein delivery to cells and tissues. Highlighting the various chemical, physical, and biological approaches to protein and gene delivery, the book provides guidelines for pharmaceutical researchers in academia and corporate R&D. This new edition brings updates on the delivery of therapeutic proteomics and genomics in each chapter, and newly developed chapters on the regulatory aspects of related products, CRISPR/Cas9 gene editing, and computational tools in genomics and proteomics.After an overview of the barriers to genomics and proteomics delivery, the book dives into physical, chemical, and biological methods of gene delivery. Further chapters extensively discuss the delivery of proteins and therapeutic peptides through the respiratory, oral, parenteral, transdermal, topical, uterine, and rectal pathways. This book is the ideal reference for pharmaceutical scientists dealing with gene and protein/peptide delivery. Regulators and corporate researchers can also benefit from the wide coverage of delivery methods presented.

  • The Nervous System

    • 1st Edition
    • Volume 5
    • Mayeen Uddin Khandaker + 1 more
    • English
    The series Stem Cell Innovation in Health and Disease is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Nervous System, Volume 5 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the nervous system. This volume will highlight the recent development of cutting edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat nervous system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Thermal-Hydraulic Principles and Safety Analysis Guidelines of PWRs and iPWR-SMRs

    • 1st Edition
    • Christophe Herer
    • English
    Thermal-Hydraulic Principles and Safety Analysis Guidelines of PWRs and SMRs presents key phenomena, models, advantages, and drawbacks of current methods. The book guides the reader through the preparation and review of the thermal-hydraulic part of a safety analysis report and equips them with the knowledge to perform thermal-hydraulic studies with confidence. Starting with an introduction to thermal-hydraulics and two-phase flows, the book covers key models such as the Homogeneous Equilibrium Model and Drift Flux, Main Phenomena and associated models, including critical flow, heat transfer and void fraction, and then moves onto cover nuclear safety analyses and code.It contains fundamental tools to help readers understand complicated phenomena that can happen in various accidental conditions, along with key principles to help readers when using advanced simulation tools. This book is suitable for a broad audience, including non-specialized readers seeking independent advice and technicians or engineers working in nuclear facilities. It will provide students in engineering disciplines with a solid understanding of the thermal-hydraulics of nuclear reactors and safety, which will enable them to work safely and efficiently and drive research forward.

  • Leadership and Management Practices in Human Services Organizations

    EnvisionSMARTâ„¢: A Melmark Model of Administration and Operation
    • 1st Edition
    • Rita M. Gardner + 4 more
    • English
    Management, Operation, and Program Development in Human Services Organizations: EnvisionSMARTâ„¢: A Melmark Model of Administration and Operation is the fourth guidebook in the EnvisionSMARTâ„¢ series addressing leadership and management practices in human services organizations for persons with intellectual and developmental disabilities. The authors describe a model of administration and operation formed from the disciplines of applied behavior analysis (ABA) and organizational behavior management (OBM). Critical components of organizational design and responsiveness are presented, with chapters devoted to behavior, clinical, and health safety, diversity-equity-inc... (DEI), assessment and evaluation, and practice-research dissemination. The guidebook illustrates systems-wide implementation of assessment, measurement, intervention and evaluation procedures, includes many practice protocols, and details the evidence-support for programmatic recommendations.

  • Innovations in Biomedical Engineering

    Trends in Scientific Advances and Applications
    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Innovations in Biomedical Engineering: Trends in Scientific Advances and Application addresses the burgeoning demand for a comprehensive resource that not only showcases the latest advancements in this dynamic field but also shows how these innovations can be effectively translated into real-world applications. In essence, the book acts as a bridge, connecting discoveries, research, and innovations in biomedical engineering to tangible, real-world applications.

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