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Academic Press

Pharmacology in Drug Discovery and Development
Understanding Drug Response
3rd Edition
Terry P. Kenakin
English
Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.
Advances in Artificial Intelligence
Biomedical Engineering Applications in Signals and Imaging
1st Edition
Kunal Pal + 2 more
English
Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of artificial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.
Nucleic acid associated mechanisms in immunity and disease
1st Edition
Volume 161
English
Advances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Engineering Analysis
Advanced Mathematical Methods for Engineers
1st Edition
Zhihe Jin
English
Engineering Analysis: Advanced Mathematical Methods for Engineers introduces graduate engineering students to the fundamental but advanced mathematics tools used in engineering application, especially in mechanical, aerospace, and civil engineering. Most engineering problems are described by differential equations, particularly partial differential equations (PDEs). Deformation and failure in solid structures, fluid flow, heat transfer, and mass diffusion are all governed by PDEs in general. Many physical quantities in engineering are tensors, including deformation gradient, strain rates, stresses, elastic stiffness, and thermal conductivity of composite materials. This book helps engineering graduate students develop the skills to establish the mathematical models of engineering problems and to solve the problems described by the mathematical models.
Plant Biomass Applications
Materials, Modification and Characterization
1st Edition
Mohammad Jawaid + 2 more
English
Plant Biomass Application: Materials, Modification and Characterization focuses on the unique properties associated with plant biomass, from their biodegradable, non toxic, and safe for handling characteristics to their potential in developing sustainable, climate protecting products. The book covers all aspects of plant biomass materials opportunities, with a focus on the value-added product generated from plant biomass such as polymers, composites, transportation fuels, chemical intermediates/bulk chemicals, or sources of heat and generated power. The conversion of plant biomass into materials product such as plastics, fabrics, and carpets and specialty chemicals presents exciting possibilities for replacing traditionally used fossil fuels. Sections in this new release provide in-depth discussion on the materials derived from plant biomass and their current and potential future applications. Leading researchers from industries, academics, government, and private research institutions across the globe provided insights, making it an important reference for researchers and academics seeking to maximize plant biomass potential.
Comprehensive Chirality
2nd Edition
Janine Cossy
English
Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals. Key highlights include:- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.- Asymmetric Photochemistry: light-induced asymmetric transformations.- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers.
Phylogenomics
Foundations, Methods, and Pathogen Analysis
1st Edition
Igor Mokrousov + 1 more
English
Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.
Advances in Clinical Chemistry
1st Edition
Volume 120
English
Advances in Clinical Chemistry, Volume 120, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.
Immunology for Engineers
1st Edition
Volume 140
English
Immunology for Engineers, Volume 140 consists of chapters from stalwarts of the field, covering topics such as antibody engineering, adjuvant requirement and its methodology for assessment, and the need to develop immunotherapy, etc. Chapters covered in this volume discuss Current Status and Future Prospective of Breast Cancer Immunotherapy, Engineering high affinity antigen binders- beyond antibodies, Platelets and Inter-Cellular Communication in Immune Responses: Dialogue with both Professional and Non-Professional Immune Cells, Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapy: A boon for cancer-free life, and Molecular insights and promise of Oncolytic Virus based Immunotherapy.
An Introduction to Probability and Statistical Inference
3rd Edition
George G. Roussas
English
An Introduction to Probability and Statistical Inference, Third Edition guides the reader through probability models and statistical methods to develop critical-thinking skills. Written by award-winning author George Roussas, this valuable text introduces a thinking process to help users obtain the best solution to a posed question or situation and provides a plethora of examples and exercises to illustrate applying statistical methods to different situations.

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