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Elsevier

Books in Life sciences

  • Advances in Cancer Research

    • 1st Edition
    • Volume 172
    • English
    Advances in Cancer Research, Volume 172 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Memantine and its Analogs: Potential Applications in Cancer Therapy, The role of epigenetic modifications in mediating cancer health disparities, Tumor Associated Macrophages: Ontogeny, Plasticity, Spatial Ecosystems, and Therapeutic Targeting, Recognizing the significance of cancer-nerve crosstalk in advanced prostate cancer, and much more.

  • Molecular Insights into Proteinopathies

    Increased Scope from Neurodegeneration to other Pathologies of the Brain
    • 1st Edition
    • Eva Žerovnik + 1 more
    • English
    Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.

  • Advancing Body Fluid Diagnostics with Flow Cytometry

    A Comprehensive Guide to Effusions and CSF
    • 1st Edition
    • Namrata P. Awasthi
    • English
    Advancements in Pathological Diagnosis: Harnessing Flow Cytometry for Detection of Malignant Epithelial Cells in Body Fluids is an invaluable resource for anyone involved in cytology and pathology, especially those interested in leveraging flow cytometry for diagnostic purposes. The book offers a comprehensive understanding of how flow cytometry can enhance the detection of malignant epithelial cells in body fluids, providing both theoretical knowledge and practical guidance. Flow cytometry's ability to rapidly analyze individual cells based on their properties is truly remarkable, and its application in detecting early-stage malignancies and screening large numbers of cells efficiently is invaluable. The book bridges the gap between traditional cytological diagnostics and the evolving landscape of technological advancements in pathology. Moreover, the inclusion of detailed chapters on flow cytometry and its applications in cytological diagnostics for effusion samples suggests that the book caters to both beginners in the field and seasoned professionals seeking to expand their knowledge base. The endorsement from medical professionals such as medical oncologists, surgical oncologists, gastroenterologists, and general surgeons further underscores the relevance and practicality of the book in enhancing diagnostics and patient care across various medical specialties. "Advancements in Pathological Diagnosis" is a timely and essential contribution to the field of cytology and pathology, offering a comprehensive guide to leveraging flow cytometry for improved diagnostics in the context of malignant epithelial cells in body fluids.

  • Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture

    • 1st Edition
    • Douglas P. Beall
    • English
    Worldwide, vertebral compression fractures (VCFs) continue to be the most common major fragility fracture, affecting patients over the age of 50, and osteoporosis is the most prevalent condition associated with VCFs. Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture provides treatment and management guidance of the osteoporosis disease process in patients who have had a VCF. This book opens with a foundation of osteoporosis and VCF and then reviews clinical and radiological assessment approaches, evaluation, treatment, and ongoing management options. Subsequent chapters cover the efficacy of the different vertebral augmentation types on patient outcomes, optimization methods, decisions for osteoporosis treatment in these patients, and recommendations to improve patient outcomes. Special attention is paid to the treatment sequence and objectives following an osteoporotic VCF. This book concludes with coverage of insightful developments in clinical management and current research and features targeted case studies representing common patient characteristics that showcase varying aspects of different VCFs and the underlying osteoporosis that gives rise to these fractures. This title serves as an invaluable resource for any practitioner managing fragility fractures in older patients as well as treating their underlying osteoporosis.

  • Exploring Health Benefits of Phenolic Compounds in Food By-Products and Functional Foods

    • 1st Edition
    • Abdur Rauf + 1 more
    • English
    Exploring Health Benefits of Phenolic Compounds in Food By-Products and Functional Foods investigates the diverse sources of bioactive compounds found in various foods and their physiological effects on the human body. This comprehensive volume emphasizes the chemical structures that maximize nutritional benefits, offering insights into how different phenolic compounds can improve health and manage diseases. From fruits and vegetables to marine sources and microbial fermentation, this book highlights new developments in phenolic compounds and functional food research.The book also delves into the functional attributes of ingredients like mushrooms and pomegranates, exploring the potential of flavonoids and antibacterial agents in certain fruits and vegetables to promote healing and overall health. Chapter authors discuss the role of bioactive compounds in areas such as weight management, gut health, sports nutrition, cardiovascular health, and more.

  • Innovations and Human Factors Challenges in Healthcare Product Design

    • 1st Edition
    • Kamalpreet Sandhu + 3 more
    • English
    Innovations and Human Factors Challenges in Healthcare Product Design covers best practices and advanced design methods to capture, document, and validate various challenges at the early stage of the design process, also delving into how to mitigate design strategies to address those challenges without compromising the cost, effort, safety, and quality of the device. The book provides a comprehensive collection of technical notes, research designs, design methods and processes, case studies, comprehensive literature on the industrial impact of design methods and processes, and applications of digital technologies for design, analysis, manufacturing, testing, and deployment. Readers will find multidisciplinary coverage of the application of technology and science for product design in healthcare sectors.

  • Erythropoiesis/Hematopoiesis

    • 1st Edition
    • Volume 170
    • English
    Erythropoiesis/Hemat... Volume 170 provides a comprehensive overview of erythropoiesis and hematopoiesis—the processes by which blood cells are formed, developed, and maintained in the body. The book covers the molecular, cellular, and physiological mechanisms that regulate the formation of red blood cells (erythropoiesis) and all other blood cell lineages (hematopoiesis), including stem cell biology, signaling pathways, and genetic regulation. Timely chapters in this new release include Ribosomal RNA transcription in normal and leukemic hematopoiesis, Regulation of erythroid development by iron metabolism, Mediator at the Helm: Coordinating Transcription and Biomolecular Condensates in Hematopoiesis, and much more.Additional chapters explore Cell fate decision and lineage specification mechanisms in hematopoiesis, Hijacking the Host: Red Blood Cell Remodeling and Extracellular Vesicle Release During Babesia Infection, How advances in chromosome conformation capture methods are reshaping our understanding of gene regulation in haematopoiesis, Post-transcriptional regulation in erythropoiesis, Erythropoiesis resolved through spatial omics, and Transcription elongation mechanisms that control gene expression in erythropoiesis.

  • Advancements in Neuropsychology and Neuroscience

    Understanding the Complexities of the Brain
    • 1st Edition
    • Jitendra Kumar Sinha + 1 more
    • English
    Advancements in Neuropsychology and Neuroscience: Understanding the Complexities of the Brain is a comprehensive exploration of the latest developments in the field of neuropsychology and neuroscience. With contributions from leading experts in the field, this book delves into the most recent discoveries, cutting-edge research, and innovative methodologies, providing readers with a roadmap to understanding the complexities of the brain. It will serve as an essential resource for researchers, offering a deep dive into the intricate world of the human brain, cognitive processes, and neurological disorders.

  • Advances in Biomedical Engineering - Part B

    • 1st Edition
    • Volume 405
    • English
    Advances in Biomedical Engineering – Part B, Volume 405 presents the latest developments, research trends, and methodologies in the evolving field of biomedical engineering. This volume covers a range of topics, including advanced medical devices, biomaterials, biomedical imaging, tissue engineering, biomechanics, and computational modeling. Specific chapters in this new release include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery system, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review, and more.Contributions from leading experts highlight both theoretical advancements and practical applications designed to improve healthcare diagnostics, treatment, and patient outcomes. This comprehensive resource is ideal for researchers, practitioners, and students seeking to stay informed about cutting-edge technologies and future directions in biomedical engineering.

  • Novel Strategies to Improve the Eating and Nutritional Properties of Food Products

    • 1st Edition
    • Volume 122
    • English
    Advances in Food and Nutrition Research, Volume 122, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Pathway-Oriented Strategies for Nitrosamine Mitigation in Food Products: Plant-Based Inhibitors and Emerging Processing Technologies, Innovations in Processing and Formulation for Tailoring Eating Quality and Nutrition of Meat-Based Foods, Hybrid food design as a way to enhance the nutritional and functional properties of animal-based products Enhancing Food Digestibility through Ultrasound Technology: Mechanisms, Applications, and Future Prospects, Ingredient innovations, and much more.Additional sections cover Nutritional Adequacy and Novel Food Products, Lipid and protein oxidation of foods and their implications to food quality and health and diseases, and Nexus of Innovative Packaging, Food Quality and Sustainability.

  • Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Food Systems

    Advances and Opportunities in Product Formulation, Technology, and Delivery
    • 1st Edition
    • Pothiyappan Karthik + 3 more
    • English
    Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Food Systems: Advances and Opportunities in Product Formulation, Technology and Delivery introduces readers to the health and nutritional benefits for DHA and EPA in inflammation regulation, advances in new delivery systems, commercialization strategies, and the use of PUFAs in functional foods and new product development. The book not only provides practical guidance for formulating PUFA-enriched products for maximum health benefits, but also explores emerging trends and opportunities, including the development of novel functional foods, nutraceuticals, the role of microorganisms as a promising source of microbial oils, and personalized nutrition solutions.With detailed information on how PUFAs can be effectively and sustainably sourced, processed, formulated, and marketed in the food industry, readers will better understand and learn how to overcome the challenges of scaling up PUFA production for industrial use and maximum nutritional value. Researchers, grad students working in the fields of nutrition, food science, and biochemistry, and industry professionals in the food and pharmaceutical industries involved in product development, functional foods, and formulation will benefit from this book.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 134
    • English
    Advances in Clinical Chemistry, Volume 134 in this ongoing series, examines physiologic and pathophysiologic biochemistry and impacts on Clinical Chemistry testing and design. Sections cover Molecular mechanisms of disease and advances in the development of improved diagnostic and predictive biomarkers. Specific chapters in this new release include Biomarkers in Heart Failure, RNA biomarkers in antidoping, Cardiovascular disease and miRNA, Chronic low-grade inflammation in vegetarians and vegans: biomarker evidence and methodological considerations, Advances in microfluidic extracellular vesicle technology, and Biomarkers for Assessing Magnesium Status.As these evolving technologies and analytic strategies have become increasing relevant given the healthcare and socioeconomic impact worldwide, this book provides an essential reference.

  • Vertebrate Carbonic Anhydrases

    • 1st Edition
    • Volume 59
    • English
    Vertebrate Carbonic Anhydrases, Volume 59 in The Enzymes series, explores recent advances in the study of carbonic anhydrases (CAs) in vertebrate systems. This volume presents a comprehensive collection of chapters examining the diversity, structure, function, and physiological roles of vertebrate CA isoforms across multiple tissues and cellular compartments. Chapters include discussions on the phylogenetic relationships of vertebrate carbonic anhydrases and detailed examinations of several important isoforms, including carbonic anhydrases I, II, and III, as well as membrane-associated enzymes such as CA IV and XV. Additional contributions explore mitochondrial carbonic anhydrases (CA VA and VB), secreted isoforms such as CA VI, and more.The volume also examines acatalytic carbonic anhydrases and tumor-associated isoforms, providing insights into their structural characteristics and biological significance. A concluding chapter addresses current challenges and opportunities in the development of selective inhibitors and activators targeting vertebrate carbonic anhydrase isoforms, highlighting their potential therapeutic applications.

  • Foundation of Microfluidics Device Technology

    • 1st Edition
    • Volume 225
    • English
    Foundation of Microfluidics Device Technology, Volume 225 presents the fundamentals of microfluidics and microfluidics devices, including computational design and fabrication, artificial intelligence and internet of things for microfluidics devices, materials, surface modifications and functionalization of microfluidics, fabrication of paper based microfluidics. Additional topics include microfluidics for generation of biomaterials, microfluidics for multi-omics analysis, lab-on-the-chip, microfluidics for 2D and 3D cell culture systems, microfluidics for drug and gene delivery, biomimetic models, and the economic considerations associated with microfluidics devices development.Specific chapters in this new release include An introduction to microfluidics and devices, Computational design and modeling of microfluidics devices, Artificial intelligence and IoT for microfluidics devices, Fabrication techniques for design of microfluidics devices, Materials, surface modification and functionalization of microfluidic devices, Fabrication of paper based microfluidics, Microfluidics in biomaterials generation and formulation, Microfluidics for chemical and biological analysis, and more.

  • Digital Transformation in Healthcare

    Innovations in Hospital and Medical Services
    • 1st Edition
    • Patricia Ordonez de Pablos + 1 more
    • English
    Digital Transformation in Healthcare: Innovations in Hospital and Medical Services explores the digital revolution in healthcare, addressing the challenges and opportunities faced by hospitals, medical faculties, and research institutions. The book highlights the role of advanced information technologies in providing innovative solutions for an ageing population's well-being. It covers critical areas such as hospital management, adapting medical education to digital advancements, and emerging IT tools in healthcare. The book features contributions from leading academics and practitioners worldwide, discussing topics like 5G, AI, big data, blockchain, and digital tools for citizen empowerment, supported by real-world case studies. This resource is invaluable for academics, offering new insights to shape innovative policies in healthcare, education, and information technologies. It fosters dialogue among managers, students, policymakers, and healthcare professionals, contributing to the global advancement of digital healthcare practices.

  • Advances in Biosensor Technology for Mycobacterium Tuberculosis Detection

    • 1st Edition
    • Mansi Chaturvedi + 3 more
    • English
    Advances in Biosensor Technology for Mycobacterium Tuberculosis Detection provides an interdisciplinary overview of Mycobacterium tuberculosis (MTb) and various biosensing techniques for the Mycobacterium tuberculosis (MTb) detection and diagnosis. The book covers detailed information about the Mycobacterium tuberculosis bacteria, its pathogenesis, and the global health challenges caused by tuberculosis. It explores potential materials for biosensor development, the various types of biosensors integrated with electrochemical and fluorescence for the detection of Mtb and TB biomarkers, and their application in disease diagnosis.In addition, the book discusses the potential of advanced technologies, including AI, IoT, and POC devices for TB diagnosis. With contributions from experts in the field, this book is an informative resource for those interested in enhancing point-of-care diagnostics and accurate TB detection for the timely treatment of the disease.

  • Probiotics

    A Comprehensive Exploration of Health Benefits and Innovation
    • 1st Edition
    • Ranbir Chander Sobti
    • English
    Probiotics: A Comprehensive Exploration of Health Benefits and Innovation explores the potential of probiotics and their fundamental role in human health and disease prevention. The book offers a thorough understanding of how beneficial microorganisms can enhance overall well-being and potentially transform treatment approaches across multiple disciplines. The first section lays the groundwork by exploring the fundamentals of probiotics, prebiotics, and their interactions with the human microbiome, while the second section examines the role of probiotics in disease prevention and management, highlighting their impact on conditions such as diabetes, obesity, and mental health.The third section discusses specialized applications of probiotics in women's health, pediatrics, and geriatrics, as well as their innovative uses in skin care and nutrition. Finally, the fourth section investigates the future potential of probiotics in synthetic biology, in personalized health, and in combatting antibiotic resistance. With contributions from a diverse group of experts in the field, the book serves as an interdisciplinary resource for researchers, clinicians, and industry professionals eager to explore the therapeutic potential and benefits of probiotics.

  • Pediatric Pulmonology

    A Global Handbook for Clinical Care Providers
    • 1st Edition
    • Allen J. Dozor
    • English
    Pediatric Pulmonology: A Global Handbook for Clinical Care Providers provides an in-depth exploration of pediatric respiratory diseases, offering a detailed examination of various conditions, diagnostic techniques, and treatment protocols. The book covers a wide range of topics, from the assessment of children with respiratory diseases to specific conditions such as asthma, cystic fibrosis, and bronchopulmonary dysplasia. Each chapter is contributed to by leading experts in the field, ensuring that the content is both authoritative and up-to-date. These crucial, practical skills are essential when a pediatric patient's first point-of-care is not a respiratory specialist.This is especially true of medical treatment in resource-poor areas. The book includes "how to guides" on vital procedures such as spirometry, chest imaging, and the management of respiratory emergencies. It also addresses respiratory diseases in newborns, the impact of environmental factors on children's respiratory health, and the unique challenges faced by children with neurologic and neuromuscular diseases. This comprehensive approach ensures that non-specialists gain a holistic understanding of pediatric respiratory diseases and their management.

  • Nano Drug Delivery Systems for Colon Cancer

    Innovations, Challenges, and Applications
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nano Drug Delivery for Colon Cancer: Innovations, Challenges, and Applications is a breakthrough exploration that delves into the latest advancements in colon cancer diagnosis and treatment. This comprehensive guide, composed of 11 detailed chapters, focuses on the design, synthesis, and application of various nanodrug delivery systems, showcasing how nanoparticulate drug carriers can significantly enhance therapeutic efficacy through strategic design. Aimed at graduates, clinical researchers, and scientists, this book addresses the complexities and challenges in drug and gene delivery. Beyond its technical insights, the book highlights the global health impact of colon cancer and offers a roadmap for developing more efficient and targeted treatments.It serves as a vital resource, fostering interdisciplinary knowledge and advancements that have the potential to revolutionize colon cancer therapeutics. The book's interdisciplinary approach ensures it is a beacon of knowledge for those seeking to navigate and innovate within this critical field.

  • Thiamine and Thiamine-Pyrophosphate (TPP) Riboswitches

    • 1st Edition
    • Volume 735
    • English
    This volume of "Methods in Enzymology" series is devoted to the cofactor thiamine, also known as vitamin B1, and its phosphorylated derivatives. The biosynthesis of thiamine is discussed in terms of key enzymes and their regulation, the evolution of metabolic pathways, and its importance in plant and yeast metabolism. The importance of quantifying and distinguishing between phosphorylated and unphosphorylated thiamine in animal and human tissues using chromatographic, enzymatic, and nanopore methods is also discussed. In addition to these methods, thiamine riboswitches are a major focus of this book, covering everything from their identification in plants and the elucidation of their structure to their application in detection.This book presents state-of-the-art methods and detailed protocols intended for all researchers interested in thiamine metabolism or its detection.

  • Nanoengineered Therapeutics for Lung Cancer

    Advanced Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanoengineered Therapeutics for Lung Cancer: Advanced Drug Delivery Strategies explores contemporary methods for diagnosing and treating lung cancer using cutting-edge nanotechnology. The book provides a foundational understanding of lung cancer biology, detailing innovative nanodrug delivery strategies and their practical applications in treatment. The content is strategically structured, covering the design, synthesis, and application of nanodrug delivery systems. Chapters delve into specific technologies such as gold nanoparticles, exosome-mediated therapies, and siRNA-based gene silencing. The book also addresses challenges like drug resistance and toxicity, offering insights into future research directions and advancements in the field. This book benefits graduate students, researchers, and healthcare professionals by seamlessly integrating theoretical concepts with practical applications. It serves as an essential educational resource, equipping readers with the knowledge and skills needed to tackle complex challenges in lung cancer treatment using nanomedicine. This comprehensive guide ensures that readers stay at the forefront of the rapidly evolving landscape of cancer therapeutics.

  • Bioplastics for Food Packaging

    Materials, Procedures, and Applications
    • 1st Edition
    • Mehran Ghasemlou + 1 more
    • English
    Bioplastics for Food Packaging: Materials, Procedures, and Applications offers a comprehensive overview of the fundamentals and recent developments in the field of bioplastics tailored specifically for food packaging applications. Covering critical topics such as the environmental impact of plastic waste and the regulatory landscape driving the adoption of bioplastics in the food industry, this book discusses the unique benefits and drawbacks associated with different types of bioplastics. It explores practical applications of bioplastic flexible films, containers, coatings, and more, and showcases real-world success stories and industry insights.This is a valuable reference for those looking to understand the application of bioplastics in the food industry and stay updated on the latest trends and innovations in bioplastics for food packaging purposes.

  • Dairy 4.0

    Revolutionizing the Dairy Sector Through Industry 4.0 Technologies
    • 1st Edition
    • Abderrahmane Aït Kaddour + 1 more
    • English
    Dairy 4.0: Revolutionizing the Dairy Sector Through Industry 4.0 Technologies explores how cutting-edge technologies like artificial intelligence, big data, smart sensors, 3D printing, blockchain, and digital twins can drive the future of dairy. The book provides a thorough understanding of Industry 4.0 technologies and their applications, promoting sustainability through improved resource efficiency, waste reduction, and environmental impact. The book also offers practical insights and case studies demonstrating the impact of technology on dairy quality, safety, and traceability. Challenges such as high initial costs, data security concerns, technological integration complexities, regulatory and ethical issues, and resistance to change are addressed.Users will find this to be a resource that stimulates innovation by showcasing the latest research and developments, thus fostering a culture of continuous improvement. The book explores opportunities and hurdles, providing insights to drive the industry's transformation and helping to create conducive regulatory environments for technological adoption.

  • Advances in Food Security & Sustainability

    • 1st Edition
    • Volume 11
    • English
    Advances in Food Security and Sustainability, Volume 11, highlights recent developments and emerging perspectives in addressing global food security challenges. This volume brings together a diverse collection of chapters written by international experts, examining the complex interactions between food systems, health, environmental sustainability, and technological innovation. Chapters in this release explore topics such as the role of artificial intelligence and machine learning in food safety, the One Health approach to food security, regional perspectives on food security in the Americas, and the relationships between diet, health, and medical outcomes, and much more.Further chapters discuss policy environments influencing food security, the application of decision analysis methods for food safety, and strategies to address micronutrient deficiencies through biofortification. The volume also addresses global and regional issues including meat consumption trends in Africa, protein security in Central Asia, the legacy of the Green Revolution, and the role of biodiversity and marine ecosystems in sustaining resilient food systems. ]

  • Cell Death Part E

    • 1st Edition
    • Volume 210
    • English
    Cell Death: Part E, Volume 210 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores the molecular mechanisms, regulatory pathways, and biological consequences of various forms of cell death—including apoptosis, necrosis, autophagy, and other non-canonical processes. Chapters in this new release include Flow cytometry analysis of mitochondrial apoptotic priming with BH3 profiling on senescent cells, Methods to study PIDDOsome and caspase 2 signaling, Isolation, characterization, and experimental applications of apoptotic bodies in vitro, Lipid ROS Measurement by Spectral Flow Cytometry based on the ratiometric dye BODIPYTM C11 581/591, and much more.Additional chapters cover CRISPR-Cas9 Screen to Identify Genes Regulating Cell Death, Flow cytometry-assisted discrimination of early apoptotic, late apoptotic and primary necrotic morphological markers in Saccharomyces cerevisiae, Cytofluorometric analysis of cell death in primary human neutrophils, Real-time tracking of cell death in human intestinal organoids: a quantitative imaging approach, and more.

  • Gene Therapy in Neurodegenerative Disorders

    From Bench to Bedside
    • 1st Edition
    • Vahid Mansouri + 1 more
    • English
    Gene Therapy in Neurodegenerative Disorders: From Bench to Bedside offers a comprehensive review of gene therapy modalities and their applications in treating neurodegenerative disorders. Initial chapters focus on the fundamentals of gene therapy strategies, including gene delivery methods and CNS-targeted gene delivery. Subsequent chapters delve into specific neurodegenerative disorders such as Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), and Alzheimer's Disease (AD), highlighting the latest gene therapy approaches for each condition. Each chapter provides a detailed introduction to the relevant field before exploring specific tools and applications.With contributions from leading experts, the book addresses current and ongoing clinical trials, potential challenges, and promising advances in gene therapy for neurodegenerative disorders. It also discusses regulatory and ethical considerations in translating research from bench to bedside. This book is an essential resource for basic science researchers in gene therapy, geneticists, biotechnologists, and clinical researchers seeking new and effective treatments for neurodegenerative diseases. It equips readers with the knowledge and tools needed to advance their work and drive innovation in gene therapy.

  • Topical Dermal Drug Delivery

    Concepts and Advances
    • 1st Edition
    • Jitender Madan + 4 more
    • English
    Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders.The book covers three major concepts. The skin anatomy and physiology part includes chapters focused on relevant information for drug delivery. The second part of the book deals with several recent topical dermal drug delivery systems, including computational methods, permeation enhancers, bio precursors, hydrogels, emugels, exosomes and several nanotechnology enabled systems. The third and final part covers scaling up, toxicity, clinical trials, and regulatory considerations.This is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the skin. Medical & Health Sciences researchers would also benefit from understanding the delivery systems covered in this book.

  • Neuroscience of Social Behavior

    Bridging the Mind and Society
    • 1st Edition
    • Mikhail Votinov
    • English
    Social behavior is fundamental to human experience, yet the neural mechanisms that govern how individuals perceive, interpret, and respond to one another are only beginning to be understood. Neuroscience of Social Behavior: Bridging the Mind and Society offers a rigorous and integrative examination of the biological foundations of social interaction, synthesizing current knowledge from neuroscience, psychology, sociology, and anthropology into a coherent framework.The book addresses the full scope of social neuroscience, from the evolutionary origins of the social brain to the challenges posed by digital communication and artificial intelligence. Core topics include social perception, language and communication, empathy, mentalizing, moral cognition, decision-making, and the neural basis of both prosocial and antisocial behavior. The text further explores how hormones and neurochemistry modulate social bonds, how social reward and pain systems shape motivation, and how clinical conditions disrupt social functioning. Computational and translational perspectives are integrated throughout, connecting laboratory findings to real-world implications.By bridging multiple levels of analysis, from neural circuits and neurochemistry to behavior and societal context, this volume equips readers with a comprehensive understanding of how the brain supports, and sometimes undermines, our capacity for social life.

  • On Human Nature

    Biology, Psychology, Ethics, Politics, and Religion
    • 2nd Edition
    • Michel Tibayrenc
    • English
    On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human biological and cultural diversity and its adaptative significance through an extensive selection of representative chapters. Edited by renowned expert Michel Tibayrenc, this second edition features updates to all major sections of the first edition and brings novel chapters covering critical advancements in human biology, psychology, behavior, ethics, and culture. It is accessible not only to specialists, but also to students, professors, industry professionals, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.The book brings together specialists from various fields, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. A globally diverse and interdisciplinary team of experts has been carefully selected to cover the breadth of topics enclosed.

  • Marine Mercury Bioaccumulation

    • 1st Edition
    • Luiz Drude de Lacerda
    • English
    Marine Mercury Bioaccumulation presents state-of-the-art research on mercury bioaccumulation in marine life. Written by leading experts in marine toxicology, this book delivers the latest information on monitoring and modeling mercury biomagnification in key marine taxa. Early chapters introduce the basic biology and ecology of how mercury travels through marine organisms and accumulates within marine food webs. Central chapters discuss the current status and exposure risks of key taxa, including marine vegetation, invertebrates, fishes, mammals, and birds. The book concludes with an assessment of human exposure to mercury through seafood products and novel modeling tools to assess environmental exposure risks and bioaccumulation.User... will find this to be a great resource for a global assessment of mercury contamination in the ocean, including biological resources, monitoring and modeling, current tools, existing research gaps, and suggestions on how to improve our monitoring and policy tools for improved safety of marine life and human consumption. This is an indispensable tool for researchers, resource managers, fisheries stakeholders, and students alike.

  • Glycobiology of the Immune System and Disease

    • 1st Edition
    • Shyamasree Ghosh + 1 more
    • English
    Glycobiology of the Immune System and Disease explores the integration of state-of-the-art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system. Glycobiology is a rapidly growing field in biology, with relevance to biomedicine, biotechnology and basic research. Considering the central role that glycans play in immune interactions, glycoproteins and carbohydrates are becoming the targets of next-generation therapeutics, vaccines and diagnostics. Programmed remodeling of host glycans can modulate infection, autoimmunity, and cancer, while microbial glycoconjugates can serve as canonical innate receptor agonists that induce B cell and T cell activation. This important reference investigates microbial and mammalian glycans and their protein-binding partners (lectins) and shows the role they play in all innate and adaptive immune responses. With its comprehensive overview of the field, it is an important resource for academicians, graduate and post graduate students as well as professors and faculty in the field of research in glycobiology and immunology.

  • Non-chicken Poultry Production

    • 1st Edition
    • Caven Mguvane Mnisi + 2 more
    • English
    Non-chicken Poultry Production focuses on the modern production of non-chicken poultry birds as alternatives to diversify animal protein options and complement conventional chicken production. The book offers a general review of the sustainable production of non-chicken birds followed by nutritional considerations for each bird of interest. Various strategies to improve the nutrition, welfare, and health of the birds are covered, with an emphasis on long-term economic viability and sustainability. It ultimately examines the future outlook for establishing long-term, sustainable production systems, helping aid academic and industry researchers meet the demand of growing populations and contributing to global food security.Demand for chicken and eggs has surged with population growth, rising income levels, and urbanization. Meeting the demand has proved a challenge for farmers and other stakeholders.

  • Enzyme Microfluidics

    • 1st Edition
    • Volume 737
    • English
    Enzyme Microfluidics, Volume 737 in the Methods in Enzymology series, presents detailed methodological descriptions and protocols that cover a wide range of microfluidics-based approaches for mechanistic enzymology, high-throughput screening, and enzyme engineering campaigns. The volume includes both established methods as well as advances in the field. Sections in this new release cover four unique sections, including Chips and Reagents, Enzyme Characterization, Enzyme Engineering, and Moving Beyond Microfluidics (from micro to nanoscale). Specific chapters delve into Joint Methods for Fabricating Microfluidic Chips, A liquid handling robotic workflow for quantifying the activity of antibiotic resistance genes (ARGs) in cell-free protein synthesis, and much more.Additional chapters cover Preparation of uniform microcrystals by droplet microfluidics for time-resolved serial crystallography, Droplet microfluidic HDX for investigating highly dynamic proteins, An Accessible, Low-Cost Platform for High-Throughput Microfluidic Enzyme Kinetics, High-Throughput Data Processing, DA-MEK, Mass Spectrometry of Droplets, Digital Bioassay Using a Femtoliter Reactor Array Device, Confocal absorbance droplet sorting, Sequence-Function Data Analysis from Microfluidics Screening, and much more.

  • Plant-Derived Feed Additives and Animal-Based Foods

    Linking Animal Health, Product Quality, and Consumer Perceptions
    • 1st Edition
    • Mohamed E. Abd El-Hack
    • English
    Plant-Derived Feed Additives and Animal-Based Foods: Linking Animal Health, Product Quality, and Consumer Perceptions presents a comprehensive, multidisciplinary exploration of how plant-based feed additives, or phytogenics, can transform animal nutrition to improve livestock gut health, enhance product quality, and ultimately benefit consumer health. Moving beyond conventional feeding practices, this book integrates cutting-edge science on oxidative stress, inflammation, bioactive phytochemicals, and gut microbiota modulation. It covers a broad range of interdisciplinary topics from animal welfare to consumer science, and offers a unique “farm-to-fork” perspective that connects animal feed science with public health and sustainability. Organized into thirteen insightful chapters, Plant-derived Feed Additives and Animal-based Foods addresses key themes such as functional phyto-feed mechanisms, product quality, ethical and environmental considerations, regulatory frameworks, and future trends at the feed-food-health nexus. Designed for animal agriculturalists, veterinarians, and food scientists, this book provides both foundational knowledge and practical guidance for implementing ethical, sustainable, and economically viable feed interventions.

  • Fish Feed Formulation with Agroindustrial Wastes and Byproducts

    • 1st Edition
    • Hrudayanath Thatoi + 3 more
    • English
    Fish Feed Formulation with Agroindustrial Wastes and Byproducts provides a comprehensive examination of various agrodindustrial wastes and byproducts, detailing their nutritional composition, processing techniques, and potential applications in fish feed formulation. Sections delve into future perspectives and research directions in the field of fish feed formulation with agroindustrial byproducts, offering readers a glimpse into emerging trends, technological advancements, and opportunities for innovation. This book will assist readers in staying abreast of the latest developments, anticipating future challenges and opportunities in aquafeed production, and positioning themselves to adapt and thrive in an ever-evolving industry landscape.Readers will gain valuable insights into the diverse range of alternative feed ingredients available, allowing them to make informed decisions regarding ingredient selection and formulation strategies. Written and edited by a diverse team of aquaculture specialists, this book includes practical case studies to provide readers with concrete illustrations of how agroindustrial wastes can be effectively utilized in commercial aquafeed production.

  • Analytics and Laboratory Testing Protocols for Halal Food and Non-Food Products

    • 1st Edition
    • Syed Ghulam Musharraf
    • English
    Analytics and Laboratory Testing Protocols for Halal Food and Non-Food Products is a comprehensive exploration of the diverse field of Halal research and laboratory testing that dives into the scientific advancements necessary for ensuring compliance with Halal standards. The book introduces readers to methodologies and technologies used in laboratory testing, equipping them with the knowledge needed to adopt best practices and ensure compliance with Halal standards. It offers guidance on quality assurance measures and testing protocols, enabling readers to uphold the highest standards of Halal authenticity and enhance consumer confidence and brand reputation.This is an essential resource for graduate students and researchers in food sciences, analytical chemistry, and pharmaceutical sciences who want to check non-Halal ingredients and stay up-to-date with the latest developments in Halal assurance and quality control.

  • Navigating Health Research

    From Fundamentals to Advanced Practices in Biostatistics and Study Design
    • 1st Edition
    • Aliaa Rehan Youssef + 3 more
    • English
    Navigating Health Research: From Fundamentals to Advanced Practices in Biostatistics is an essential resource for students, scientists, and clinicians embarking on their research journeys. This book clarifies research methodology and regulation while providing foundational knowledge in biostatistics through clear explanations and illustrative examples. Covering both classical and modern advancements in health research, it addresses topics such as health economics, artificial intelligence, and bioinformatics. The book offers a step-by-step guide through the research lifecycle, tackling challenges like study design flaws and ethical compliance. Emphasizing open-source software and freely available resources, it ensures accessibility for researchers from diverse socioeconomic backgrounds. With a multi-generational and multicultural perspective, this book enhances its relevance for a broad audience. By simplifying complex topics and promoting best practices, it empowers early-career researchers and clinicians to improve their skills, elevate the quality of their work, and contribute meaningfully to evidence-based practice in health research.

  • Artificial Intelligence in Brain Disorders

    Innovations in Diagnosis and Treatment
    • 1st Edition
    • Pranav Kumar Prabhakar + 3 more
    • English
    Artificial Intelligence in Brain Disorders: Innovations in Diagnosis and Treatment focuses on the utilization of AI and machine learning to enhance current practices in the diagnosis and treatment of neurological disorders. Each chapter provides in-depth exploration of specific areas where AI can improve existing methodologies, offering practical guidance, case studies, and research findings that can be directly applied in the field. It explains the application of AI in diagnosing and treating major neurological illnesses and showcases the potential of AI in predicting diseases such as epilepsy and neurodegenerative disorders.As such, this book offers a detailed overview of AI and machine learning techniques relevant to neurological research.

  • Artificial Intelligence and the Water-Energy-Food Nexus

    Innovations for Sustainable Resource Management
    • 1st Edition
    • Ali Fares
    • English
    Artificial Intelligence and the Water-Energy-Food Nexus: Innovations for Sustainable Resource Management is a groundbreaking exploration on how AI transforms the management of our planet's most vital resources. Specific topics include enhancing poultry production and the predictions of crop yields and post-harvest processing, while also dealing with FEW security in sub-Saharan Africa. Additionally, the book covers various topics that showcase AI's potential to boost agricultural productivity, mitigate climate change, and promote food security. This book's content covers ethical considerations, interdisciplinary collaboration, and the integration of AI into real-world practices.Readers will find an in-depth analysis of the intersections of AI and the FEW Nexus, including the critical need for sustainable farming practices, water conservation, and energy efficiency. Contributing authors are experts from around the globe who offer practical solutions, case studies, and cutting-edge technologies like digital twins, machine learning, and hyperspectral imaging to optimize resource management.

  • Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders

    • 1st Edition
    • Moyra Smith
    • English
    Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders explores the latest breakthroughs in genomics and neurosciences, providing essential insights for understanding, diagnosing, and managing neurodevelopmental, psychiatric, and neurodegenerative disorders. The book highlights the intersection of genetic and genomic diagnostic techniques with brain function and structure analysis to enhance therapeutic strategies. Sections cover a wide range of topics, including the analysis of brain circuits, synapses, and neural activity, as well as the role of ion channels and neurotrophins in brain function. It examines advanced genetic and genomic diagnostic methods such as chromosome studies, gene sequencing, RNA analysis, and metabolite profiling.The book also addresses neurodevelopmental disorders like cerebral palsy, epilepsy, and autism, psychiatric disorders such as schizophrenia and thought disorders, and the molecular biology of memory and age-related cognitive decline. Organized into five sections, the book includes chapters on the latest techniques for brain analysis, genetic diagnostics, neurodevelopmental and psychiatric disorders, aging-related impairments, and new therapeutic approaches. Key topics include brain regions and circuits, new methods for studying these areas, and the relevance of this information for accurate diagnosis and patient care.

  • Advances in Agronomy

    • 1st Edition
    • Volume 200
    • English
    Advances in Agronomy, Volume 200, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Advances in Parasitology

    • 1st Edition
    • Volume 133
    • English
    Advances in Parasitology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • The Hormonal Treatment of Endometriosis and Adenomyosis

    A Comprehensive Review of the Role of Hormonal Treatments in the Management of Pain and Infertility in Patients with Endometriosis and Adenomyosis
    • 1st Edition
    • Antoine Naem + 1 more
    • English
    The Hormonal Treatment of Endometriosis and Adenomyosis: A Comprehensive Review of the Role of Hormonal Treatments in the Management of Pain and Infertility in Patients with Endometriosis and Adenomyosis is a comprehensive and practical reference on the effects of various hormonal treatments on endometriosis and adenomyosis lesions. The book summarizes the latest evidence regarding the safety and efficacy of these treatments in managing pain associated with these conditions. Additionally, the book explores the evidence-based benefits of hormonal therapies in improving fertility chances for patients, both through natural conception and assisted reproductive technologies.The book helps readers grasp the generalizability of current research findings and identifies existing research gaps, shedding light on new perspectives for future investigation. Through this comprehensive approach, the book serves as an invaluable resource for healthcare professionals, researchers, and patients alike.

  • Innovative Strategies Against Blood Parasites

    Advancing Control Through Natural Products and Next-Generation Technologies
    • 1st Edition
    • Mohamed Dkhil
    • English
    Innovative Strategies Against Blood Parasites: Advancing Control Through Natural Products and Next-Generation Technologies explores innovative strategies for controlling blood parasitic diseases by combining natural products with next-generation technologies like nanotechnology and AI. The book provides a multidisciplinary approach to developing sustainable, effective, and accessible therapies to combat drug resistance and improve patient outcomes. Bridging traditional pharmacognosy with modern biomedical advances, the volume covers natural antiparasitic compounds, nanomedicine-based delivery systems, and computational tools such as genomics and machine learning.It features case studies, practical applications, and future perspectives, serving as an essential resource for researchers, clinicians, policymakers, and students involved in parasitology, tropical medicine, and drug discovery.

  • Sustainable Agriculture

    Technologies, Application, and Practices
    • 1st Edition
    • Wasswa Shafik
    • English
    Sustainable Agriculture: Technologies, Application, and Practices provides readers with a foundational understanding of sustainable agriculture principles alongside the cutting-edge capabilities of artificial intelligence. Structured into six well-organized sections, the book begins with foundational concepts of sustainability and the enabling technologies that support them. This includes in-depth discussions on the principles of sustainability, the role of technology in enhancing agricultural practices, and the socioeconomic impacts of sustainable farming. Subsequent chapters look into practical applications, showcasing how smart irrigation, crop monitoring, and supply chain optimization can significantly bolster sustainable operations.Each chapter provides case studies and practical strategies to ensure a thorough understanding of how artificial intelligence can revolutionize sustainable agriculture. This book serves as an essential resource for upper-level undergraduate and graduate students studying sustainable agriculture, agricultural technology, and environmental science.

  • Signal Processing-Driven AI for Healthcare

    • 1st Edition
    • Ildar Rakhmatulin + 1 more
    • English
    Signal Processing-Driven AI for Healthcare examines how AI techniques can be applied across four major biosignals—EEG, EMG, EOG, and ECG—to derive clinically meaningful insights. As biomedical data becomes increasingly multimodal, there is a rising need for integrated methodologies that unite these signals within robust, explainable AI pipelines suitable for healthcare environments. This book provides a unified framework that spans data acquisition, preprocessing, feature extraction, modeling, evaluation, and deployment, with an emphasis on reproducibility, practical Python-based implementations, and real-world translation to clinical workflows.

  • Nutraceutical Applications in Food Processing and Preservation

    • 1st Edition
    • M. Anuradha + 1 more
    • English
    Nutraceutical Applications in Food Processing and Preservation addresses the urgent need for healthier and safer food processing methods by integrating nutraceuticals as natural alternatives to conventional additives. The book explores the intersection of food science, nutrition, and biotechnology to seek innovative solutions to enhance food safety and nutritional value amid rising consumer health consciousness. The contents encompass an in-depth analysis of food additives and their evolution, a detailed coverage of various nutraceutical types such as phytochemicals and probiotics, and practical applications across beverages, snacks, dairy, bakery, and meat alternatives.The book also includes case studies that showcase successful nutraceutical substitutions, discussions on regulatory compliance, sustainability, and market trends that affect product development and food safety. By providing regulatory insights, scientific advancements, and consumer trend analyses, this reference fosters the creation of safer, health-promoting food products. It will equip food scientists, technologists, product developers, and academic researchers with actionable knowledge to innovate and improve food processing practices.

  • Inflammation in Tumorigenesis and Cancer Treatment, Volume 9

    From Molecular Mechanisms to Personalized Therapeutic Strategies
    • 1st Edition
    • Chunxiang Zhang + 1 more
    • English
    Inflammation in Tumorigenesis and Cancer Treatment: From Molecular Mechanisms to Personalized Therapeutic Strategies explores the pivotal role of inflammation in cancer. It uncovers the molecular dialogue between inflammatory factors and tumor cells, illuminating pathways that drive oncogenesis and metastasis. Highlighting the rapid pace of discovery, the book bridges the gap by translating complex data into actionable clinical strategies, catering to students and professionals and addressing personalized medicine. Early chapters focus on the fundamental concepts of inflammation in cancer and recent advances in research, while also covering the impact of inflammatory mediators on signaling pathways and oncogenesis.Other sections explore therapeutic strategies targeting inflammatory pathways and the role of immunometabolism and discuss biomarker discovery and personalized treatment plans. The final section examines the tumor microenvironment, the microbiome's role, and the intersection of immunotherapy and inflammation. The book offers numerous benefits to its audience. For scientists and researchers, it provides cutting-edge knowledge to inspire new research directions and foster interdisciplinary collaboration while serving as a valuable educational tool for the next generation of researchers.

  • Cognitive Remediation In Psychiatric Disrorders Part A: Core Psychiatric Conditions

    • 1st Edition
    • Volume 302
    • English
    Brain Rehabilitation in Psychiatric Disorders, Volume 301 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Chapters in this new release include Overview and Historical Perspective of Cognitive Rehabilitation, Fundamental Principles of Cognitive Remediation, Cognitive Rehabilitation in Attention Deficit-Hyperactivit... Disorder, Cognitive Rehabilitation in Autism Spectrum and Disorders, Cognitive Rehabilitation in Schizophrenia Spectrum and Psychosis Disorders, Cognitive Rehabilitation in Bipolar Disorders, Cognitive Rehabilitation in Mood Disorders (Depression), and much more.Additional sections cover Cognitive Rehabilitation in Mood Disorders (Anxiety), Cognitive Rehabilitation in Obsessive-Compulsive Disorders, Cognitive Rehabilitation in Trauma-related Disorders, Cognitive Rehabilitation in Eating Disorders, Cognitive Rehabilitation in Substance Use Disorders, Cognitive Rehabilitation in Behavioral Addiction Disorders (Gambling, Internet, Cognitive Rehabilitation for Patients Receiving ECT, Cognitive Rehabilitation in Disorders Affecting Cognition in Older Adults, Cognitive Rehabilitation in Personality Disorders, and Harnessing Technology to Revolutionize Cognitive Rehabilitation.

  • Fundamentals and Functional Advancements of Fungal Enzymes in Biorefinery and Bioproducts Development

    Volume 1
    • 1st Edition
    • Manikant Tripathi + 1 more
    • English
    Fundamental and Functional Advancements of Fungal Enzymes in Biorefinery and Bioproducts Development offers highlights the fundamental aspects of fungal enzymes which include their structure, function, chemical composition, and their functional importance for biorefinery and bioproducts development. This is the first of two volumes that provides a comprehensive overview of the utilization of fungal enzymes for biorefinery and bioproduct development. Volume 1 introduces various types of fungal enzymes and offers a better understanding of the basic science of fungal enzymes, their structure, their fundamental functions and limitations in biochemical development. This book also explores the processes involved in improving the enhanced production, efficiency, and efficacy of fungal enzymes for application. It also examines biofuel and bioproducts production using fungal enzymes. In combination with Volume 2, this book offers a holistic view of the potential and challenges of engineered fungal enzymes for researchers, scientists, and industry professionals seeking to deepen their knowledge of fungal enzymes and their role in biochemical advances.

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