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Elsevier

Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

  • 1st Edition - March 1, 2027
  • Latest edition
  • Editors: Dibyajyoti Banerjee, Deepak Kumar
  • Language: English

Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphas… Read more

Description

Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.

Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.

Key features

  • Describes, in detail, the pseudo esterase activity of human serum albumin as a novel classifier of diabetic nephropathy
  • Provides the latest research developments on the importance of urinary proteins with enzymatic activities as a biomarker for diabetic kidney disease discovered by a team of researchers
  • Offers insights into experimental planning, potential research topics, and the implications of early detection strategies for improved patient outcomes

Readership

Researchers working on biomarkers or diabetes mellitus or kidney diseases; Clinicians who want to be updated on recent topics of health/diabetes-related research; Entrepreneurs interested in smart ideas and technology Start-up groups on diabetes and nephropathy

Table of contents

1. Diabetes Mellitus and Its Complications

2. Diabetic Nephropathy and Microalbuminuria as Its Biomarker

3. Human Serum Albumin and Its Enzymatic Activities

4. Pseudoesterase Activity of Human Serum Albumin

5. Methods for Detecting Pseudoesterase Activity of Human Serum Albumin

6. Urinary Proteomic Profiling in Diabetic Nephropathy and the Importance of Understanding Enzymatic Profiles

7. Urinary Pseudoesterase Activity of Human Serum Albumin as a Promising Biomarker of Diabetic Nephropathy

8. Future Directions and Research Opportunities

Product details

  • Edition: 1
  • Latest edition
  • Published: March 1, 2027
  • Language: English

About the editors

DB

Dibyajyoti Banerjee

Dr Dibyajyoti Banerjee passed MBBS from North Bengal Medical College, Darjeeling, West Bengal, India in 1999 with Honors in Physiology and Biochemistry and a Gold Medal in Pathology. He was awarded an MD (Biochemistry) from Kasturba Medical College, Manipal, Karnataka, India in 2003. During the study of MD(Course), he established urinary hydrogen peroxide as a biomarker of malignancies. He is an expert in biochemistry in with research expertise in human serum albumin and POCT development. Currently, he is interested in the esterase activity of albumin and recently while working as Professor and Head, of the Department of Experimental Medicine and Biotechnology at the Postgraduate Institute of Medical Education and Research, Chandigarh, India his team discovered that pseudo esterase activity of human serum albumin has the potential to screen microalbuminuria for diagnosis of diabetic nephropathy. He has over 10 years of research experience and published ~40 articles.
Affiliations and expertise
Professor and Head, of the Department of Experimental Medicine and Biotechnology at the Postgraduate Institute of Medical Education and Research, India

DK

Deepak Kumar

Dr Deepak Kumar, PhD is Assistant Professor at the School of Bioengineering and Food Technology, Faculty of Applied Sciences and Biotechnology, Shoolini University, Himachal Pradesh, India, and holds a concurrent appointment as Project Research Scientist-III at the Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh. His research focuses on biomarker discovery, point-of-care tool development, enzymology, microalbuminuria, and molecular toxicology, with particular emphasis on the pseudoesterase activity of human serum albumin.

Dr Kumar is a lifetime member of the Association of Clinical Biochemists of India and actively reviews manuscripts for journals including Clinica Chimica Acta and Scientific Reports. His research has appeared in Clinica Chimica Acta, Talanta, Analytical Biochemistry, and Advances in Clinical Chemistry. He received a Certificate of Appreciation in the Innovation Category from PGIMER, Chandigarh in 2025.

Affiliations and expertise
Assistant Professor at the School of Bioengineering and Food Technology, Faculty of Applied Sciences and Biotechnology, Shoolini University