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Elsevier

Books in Life sciences

  • Protien Aggregation - Part A

    • 1st Edition
    • Volume 145
    • English
    Protein Aggregation, book provides valuable insights into the factors driving protein aggregation, the impact on cellular function, and the role in various diseases, offering a comprehensive overview for researchers and professionals in the field of biomedicine and biochemistry.

  • Craft Beer

    New Frontiers in Brewing Science
    • 1st Edition
    • Patrizia Romano + 2 more
    • English
    Recently, both researchers and consumers have shown strong and growing interest in craft beer, which is characterized by its small batches, local breweries, and unique varieties. Craft Beer: New Frontiers in Brewing Science provides a comprehensive picture of the craft beer market, history and legal definition, brewing processes, and the qualities and styles of the end product. It emphasizes traditional and innovative microbial resources involved in the fermentation process, as well as safety, nutrition, and emerging problems, such as the sustainability of the production process.Craft Beer: New Frontiers in Brewing Science is the first and only scientific text to comprehensively summarize this exciting field. Researchers and students in interested brewing science, as well as industry specialists from beer companies will all benefit from this unique resource.

  • Emerging Trends and Applications of Deep Learning for Biomedical Data Analysis

    • 1st Edition
    • Smita Sharma + 3 more
    • English
    Emerging Trends and Applications of Deep Learning for Biomedical Data Analysis introduces the latest emerging trends and applications of deep learning in biomedical data analysis. This book delves into various use cases where deep learning is applied in industrial, social, and personal contexts within the biomedical domain. By gaining a comprehensive understanding of deep learning in biomedical data analysis, readers will develop the skills to critically evaluate research papers, methodologies, and emerging trends. In 11 chapters, this book provides insights into the fundamentals of the latest research trends in the applications of deep learning in biosciences. With several case studies and use cases, it familiarizes the reader with a comprehensive understanding of deep learning algorithms, architectures, and methodologies speci cally applicable to biomedical data analysis. This title is an ideal reference for researchers across the biomedical sciences.

  • Handbook of Translational Transcriptomics

    Research, Protocols and Applications
    • 1st Edition
    • Anton Buzdin
    • English
    Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview of the field of transcriptomics. With an emphasis on the various protocols and techniques available for investigation, it acts as a practical guide to researchers for implementing their own investigations in the field.This book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions of choosing the correct approach based on the research needed. It also highlights the pros and cons of each approach. Following this, it explores techniques and protocols for investigating specific approaches focusing on RNA sequencing, expression arrays, and gene expression. It then delves into data analysis and offers recommendations, guidelines, and approaches related to data interpretation. This book also considers the translation of transcriptomics to clinical use and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.Handbook of Translational Transcriptomics: Research, Protocols and Applications is a detailed reference that provides a complete view of transcriptomics, ranging from methods to handling data and medical applications. This book is an invaluable guide for researchers working across molecular biology, genetics, bioinformatics and related fields, as well as graduate and PhD students in these areas.

  • Great American Diseases

    Their Effects on the Course of North American History
    • 2nd Edition
    • Ian R. Tizard + 1 more
    • English
    Great American Diseases: Their Effects on the Course of North American History, Second Edition covers significant disease epidemics that have shaped North American history, from the arrival of Smallpox with the first Europeans to the COVID-19 pandemic. It includes an introduction to the basic science of diseases, the history of vaccination in the Americas, and discussions on various diseases and their pathogens. The text concludes with a chapter on notable animal disease outbreaks. Delving deeper, the book provides engaging chapters on the societal impacts of epidemics and the evolution of medical responses.It presents a fascinating intersection of microbiology, immunology, and epidemiology enriched with contemporary outbreak examples and educational resources for biomedical students.

  • Human-Centric Integration of 6G-Enabled Technologies for Modern Society

    Fundamentals, Applications, Analysis and Challenges
    • 1st Edition
    • Amit Kumar Tyagi + 1 more
    • English
    Human-Centric Integration of 6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges serves as a comprehensive reference, addressing the information needs of professionals by providing deep information about the fundamentals and applications of 6G, enabling them to make informed decisions in the dynamic landscape of advanced communication technologies. In the 23 chapters, this book introduces the reader to the 6G technology, the evolution of wireless communication, and the integration of artificial intelligence; provides the use cases and applications of 6G technology and the insights into the challenges, future trends, and emerging technologies; and includes the applications of 6G technology in remote healthcare services, patient monitoring, and medical diagnostics.Human-Ce... Integration of 6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges redefines the way we connect, communicate, and collaborate with emerging technologies in this smart era of 6G technology. The title benefits from a collective wealth of knowledge and perspectives. This diversity enriches the content, providing readers with insights from various angles, setting it apart from publications authored or edited by a limited number of individuals.

  • Advances in 3D and 4D Printing of Medical Robots and Devices

    • 1st Edition
    • Ankit Sharma + 1 more
    • English
    Advances in 3D and 4D Printing of Medical Robots and Devices presents the most recent innovative breakthroughs in smart manufacturing and biomedical engineering to help enhance knowledge and expertise in 3D/4D printing technologies and advancements in biomedical applications through robotics and medical devices. This book highlights the usage and importance of 3D/4D printing-based prototyping as well as the manufacturing of robotic elements such as energy generators, morphology control, and novel design strategies. This book will help readers to pursue contemporary insights into currently ongoing practices in biomedical and mechatronic engineering including the fabrication of actuators manufacturing; muscles, vibration dampers, bio-inspired structures, pre-surgical and post-surgical tooling, medical assistance robots, drug delivery, microfluidic, and wearable electronics. Academic scholars, manufacturing scientists, and commercial manufacturers of bio-devices and medical robotics will find this book to be useful in adopting competent biomaterials as well as innovative techniques for applications in biomedical engineering.

  • The Use of Radioautography in Investigating Protein Synthesis

    • 1st Edition
    • C. P. Leblond + 1 more
    • English
    The Use of Radioautography in Investigating Protein Synthesis is a collection of papers that discusses the tracing of labeled proteins through photographic emulsion, particularly radioautography or autoradiography. The papers discuss proteins at the site of their synthesis, their subsequent migration through the cell, their secretions, and the formation of the basement lamella in salamanders. One paper outlines the primary aims in specimen preparation for electron microscope autoradiographic techniques and the procedures to achieve them. Another paper reports on migrating proteins (CNP) and nonmigrating proteins of the Amoeba proteus nucleus in which nonmigrating proteins are sedimentable by centrifugation in situ in the nucleus. One paper investigates the extent of protein synthesis for cell renewal in thoracic duct lymphocytes (TDL) or that for export or intracellular turnover. The protein synthesized by the large cell population in TDL is associated with mitosis and cell renewal. A major portion of that synthesized by the medium cells (80 per cent) and practically all of that produced by small cells are for purposes other than cell renewal. The collection can prove beneficial to biochemists, micro-biologists, bio-physicists, cytologists, histologists, pathologists, cellular researchers, and academicians involved in the study of cellular biology.

  • Protides of the BIological Fluids

    Proceedings of the Thirty-Sixth Colloquium, 1989
    • 1st Edition
    • H. Peeters + 1 more
    • English
    An International Review Series Devoted to Proteins and Related Studies, Volume 36: Protides of the Biological Fluids documents the proceedings of the 36th Colloquium held in 1989. This book discusses the structure of the human IgA subclasses and allotypes; comparison of normal values of IgG subclasses; and structural genetic alterations in Ig subclass deficiencies. The interleukin cascade for the regulation of IgA synthesis and immune responses; phenotypic and functional changes during T cell activation; and flow cytometric analysis of sequential tumor biopsies during therapy are also elaborated. This text likewise covers the serum and fecal proteins during Crohn's disease and isolation and properties of apolipoprotein A for therapeutic use. This publication is recommended for students and specialists conducting work on the study of proteins and techniques of their isolation, purification, and immunological quantitation.

  • Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B

    • 1st Edition
    • Volume 392
    • English
    Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B, Volume 392 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Circulating Tumor Cells in Lung Cancer: integrating stemness and heterogeneity to improve clinical utility, Multi-omic Features and Clustering Phenotypes of Circulating Tumor Cells Associated with Metastasis and Clinical Outcomes, CTCs in CRC: updates, Proteomics and post-translational modification analysis in CTCs, Latest advances of CTC studies in prostate cancer, and Epigenetics and CTCs: new biomarkers and impact on tumor biology.

  • Smart Organ-on-Chip Devices

    Dynamic Microfluidic Systems for Cell Culture
    • 1st Edition
    • Tiago Albertini Balbino + 2 more
    • English
    Smart Organ-on-Chip Devices: Dynamic Microfluidic Systems for Cell Culture discusses the concepts to engineer functional stimuli responsive organotypic-on-chip devices and its application in several fields, including drug development, disease modeling, personalized medicine, and tissue engineering. Groundbreaking studies are presented throughout the book sections to reinforce the importance of adding more reliable and robust in vitro platforms able to closely emulate the dynamism of human physiology.The authors present new information regarding in silico studies of cell spheroids within microfluidic devices, as well as step-by-step guidance on key procedures. Written for researchers, practitioners and students using microfluidic devices as platforms, by well-respected scientists from both academia and industry.

  • The Origins of Life

    From Abiotic Chemistry to the First Cells
    • 1st Edition
    • Karl Niklas + 2 more
    • English
    The Origins of Life: From Abiotic Chemistry to the First Cells is an essential textbook that tackles one of the greatest mysteries in science, how inanimate matter evolved into the first living things. The book takes an interdisciplinary approach, delving into the basic principles of the earth’s chemistry, the formation of pre-cellular entities, and the acquisition of chemical complexity. It explains the creation of chromosomes, metabolic pathways, and the features of the earliest prokaryotes. Users will find a detailed exposition of the World RNA Hypothesis in an accessible and easy-to-read style which is comprehensible for both science and non-science majors.This textbook is a critical resource for upper-level undergraduate students in Cellular Biology, specifically those studying or researching evolution, cellular chemistry, and pre-biotic chemistry, as well as non-science majors in courses on the philosophy of science or related topics. It is also useful for professionals in biochemistry, evolutionary biology, and astrobiology who wish to understand the origins of life and first cells. Science communicators could use this interdisciplinary textbook for teaching and dissemination to broader audiences as well.

  • Cryptic Enzymes and Moonlighting Proteins

    • 1st Edition
    • Helen Irving + 2 more
    • English
    Cryptic Enzymes and Moonlighting Proteins, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signaling cascades. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signaling, metabolic enzymes moonlighting as RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.The book also explores recent advances in research and brings together an array of information across different fields to enable better targeting of these exciting proteins and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, users will find examples of cryptic enzymes across species, as well as those in human healthy biology and pathogenesis.

  • Mechanical Separation Processes in the Food Industry

    Unit Operations and Processing Equipment in the Food Industry
    • 1st Edition
    • Seid Mahdi Jafari + 1 more
    • English
    Mechanical Separation Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for mechanical separation unit operations, including filtration, centrifugation, sieving, metal detection, sedimentation, etc. These processes and unit operations are very important in the manufacture of products such as cream, fruit juices, beverages, refining of edible oils and sugar. The book's chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment for mechanical separation unit operations.Written by experts in the field of food engineering, and in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

  • Kidney Development and Regeneration

    • 1st Edition
    • Volume 163
    • English
    Kidney Development and Regeneration, Volume 163 provides an up-to-date account of kidney development, congenital disease and regeneration. It has an emphasis on areas of the field that have been moving most quickly over the last few years, and that show potential for further rapid discovery. Each chapter is written by leading researchers, and their approaches range from genetics to cell biology to pharmacology to physiology to pathology to mathematical modeling. The volume is essential reading for those working on renal development, regeneration or pathology, and also those researching related aspects in similar organs.

  • Emerging Paradigms in Delivery Systems for Antitubercular Therapy

    • 1st Edition
    • Rajeev Sharma + 3 more
    • English
    Emerging Paradigms in Delivery Systems for Antitubercular Therapy provides an up-to-date and thorough overview of the state-of-the-art of concepts, design, and recent advances in nanomedicines and nanobiotechnology-ba... strategies for the treatment of tuberculosis. The book enables researchers to prepare a variety of nanotechnology-based strategies, investigate their properties, and discover their uses and applications in antitubercular therapy, focusing on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, and tuberculosis vaccination.This book covers all major topics that have shaped the development of nanomedicine and propelled it to its current place at the forefront of Nanotechnology based treatment innovation. It will be a welcomed resource for researchers and readers with more and more challenging therapy and biologicals with their possible modifications to be used for the effective therapy of tuberculosis.

  • Epidemiology of Cannabis

    Genotoxicity, Neurotoxicity, Epigenomics and Aging
    • 1st Edition
    • Albert Stuart Reece + 1 more
    • English
    Epidemiology of Cannabis: Genotoxicity, Neurotoxicity, Epigenomics and Aging provides a novel and comprehensive exploration of five areas that have previously been associated with cannabis use, namely mental health in adults and young adults, pediatric autism, congenital anomalies, cancers, and aging. The book also explores the possibility of how these associations might be reflected in overall disease trends at the population health level. This book surveys these five areas in detail and applies cutting-edge analytical software and geospatial space–time analytical techniques to these questions. With all this information gathered into one book in an easily readable form, this book is a reference for clinicians, health science and allied health practitioners, public health and basic science researchers and drug and health regulators interested in these topics. It is also suitable for inclusion in course work and study preparation courses at both the undergraduate and postgraduate levels.

  • Advances in Agronomy

    • 1st Edition
    • Volume 191
    • English
    Advances in Agronomy, Volume 191, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, with this volume presenting chapters on Climate-smart water technologies and strategies for a resilient forage production system, Principles and Application of Nitrogen Management in Precision Agriculture: A Review, No-Till System: a genuine Brazilian technology that meets current global demands, Nutrient management in crop production and dynamics of soil organic carbon in the Indo-Gangetic plains of South Asia, A Global Review of the Impacts of Saltwater Intrusion on Soils and Ecosystems, and more.Other chapters cover Optimizing nitrogen use efficiency in European livestock systems: From feed to plant growth, and Impact of Soil Erosion on Soil Organic Carbon Loss and Its Implications for Carbon Neutrality

  • Apobec Enzymes

    • 1st Edition
    • Volume 713
    • English
    Apobec Enzymes, Volume 713 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Fluorescent shift assay for APOBECs RNA editing, Low Error Sequencing Methods to Detect APOBEC-mediated RNA editing: Circular RNAseq and Safe-Sequencing System, "Safe-Barcode" RNAseq assay for APOBECs RNA editing, DT40 cell system to characterize somatic hypermutation, CH12 cell system to assay AID activity on class switch recombination, Purification of Enzymatically Active APOBEC Proteins from an Insect Cell Expression System, and more.Additional chapters cover Defining genome-wide mutagenic impact of APOBEC3 enzymes, APOBEC-induced mutational assay in yeast, Assays for APOBEC drug discovery, Biochemical assay for the identification of APOBECs inhibitors, An In Vitro Cytidine Deaminase Assay to Monitor APOBEC activity on DNA, Profiling rare C-to-U editing events via direct RNA sequencing, Global quantification of off-target activity by base editors, and so much more.

  • Navigating the Complexities of SARS-CoV-2 Immunobiology

    The Science Behind the COVID-19 Pandemic
    • 1st Edition
    • Volume 213
    • English
    Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

  • Translational Gastroenterology

    • 1st Edition
    • Adam E.M. Eltorai + 3 more
    • English
    Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

  • Current Topics in Developmental Biology

    Fertilization and Activation of Development
    • 1st Edition
    • Volume 162
    • English
    Fertilization and Activation of Development, Volume 162 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.Chapters in this new release include Fertilization and the fast block to polyspermy in the African Clawed Frog, Xenopus laevis: A historical perspective, The Mammalian Egg's Zona Pellucida, Fertilization, and Fertility, Function, structure, and regulation of the broadly conserved gamete membrane fusion protein, HAP2, Gamete activation for fertilization and seed development in flowering plants, Paternal contributions to mammalian zygote, and much more.Additional sections cover Ovarian follicle formation and activation, Cytoskeletal dynamics in gamete (pro)nuclear migration across flowering plants, animals, and yeast, and Luteinizing hormone-induced changes in the structure of mammalian preovulatory follicles.

  • Atlas of Marine Invertebrate Larvae

    • 2nd Edition
    • Michael J. Boyle + 2 more
    • English
    Atlas of Marine Invertebrate Larvae, Second Edition covers the origins and history of marine larval science, contemporary state-of-the-art approaches to larval development and biology, and the highest-quality images and schematics showing the broadest diversity of marine larvae in the animal tree of life. This book illustrates larval body plans, the anatomy of their organ systems (muscular, sensory, digestive), including distinct ciliation patterns that facilitate swimming, and the complex metamorphic changes they undergo between different larval and growth stages. Each chapter contains in-text references that direct readers to both historical and contemporary research on the forms, functions, behaviors and biogeographical distributions of marine larvae.This book is a valuable and foundational resource for biologists across various disciplines, including biodiversity, biogeography, and developmental biology. Ecologists, taxonomists, oceanographers, and environmental scientists also benefit from the complete coverage of marine larval forms offered by this book. Additionally, the broad scope and phyletic coverage of marine biodiversity presented in this atlas is ideal for students in oceanography and marine biology, animal development, biological oceanography and invertebrate zoology.

  • Chest Blunt Trauma

    A Modern Approach to a Multidisciplinary Disease
    • 1st Edition
    • Piergiorgio Solli + 1 more
    • English
    Chest Blunt Trauma: A Modern Approach to a Multidisciplinary Disease provides novel treatment ideas for cardiothoracic injuries. The book interweaves knowledge of new surgical techniques, better understanding of patho-physiologic effects of injuries, and enhanced intensive care methods to create a holistic strategy of patient support. This text is a welcome addition for any clinician or researcher seeking refreshed information on the management of trauma to the chest wall.While non-operative treatment has long been the standard of care, the book discusses the vast improvements in understanding how to treat cardiothoracic injuries. Innovative surgical techniques, instruments, post-operative care, and the multisystemic nature of this illness.

  • Gender Affirming Vaginoplasty

    • 1st Edition
    • Gennaro Selvaggi + 1 more
    • English
    Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.

  • Whole Cell Biocatalysis

    Fundamentals and Applications
    • 1st Edition
    • Sergio Huerta-Ochoa + 2 more
    • English
    Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.

  • Medicinal Plant Research in Africa

    Advances in Pharmacology and Chemistry
    • 2nd Edition
    • Victor Kuete
    • English
    Medicinal Plant Research in Africa, second edition is an updated and complete reference on the pharmacology of most relevant African species and their phytochemical properties. Although pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes, however there was no global standard book on the nature and specificity of chemicals isolated in African medicinal plants. This book has set the standard when it first published in 2013 and now is updated with novel phytochemicals belonging to diverse classes of terpenoids, phenolics, and alkaloids. The first chapter cover monoterpenes and related phytochemicals and is followed by sesquiterpenes on chapter two. Chapter tri reviews diterpenoids and chapter four provides an overview of triterpenes and steroids. Essential oils, simple phenols, phenolic acids and related esters come next in chapters five and six, respectively. The following chapters cover coumarins, flavonoids, quinones, xanthones, lignans and stilbenes. Tannins, alkaloids, and ceramides. Chapters 15 to 20 focus on specific health conditions starting with antibiotic infection, antimalarial and other antiprotozoal diseases, cytotoxic and anticancer activity, anti-inflammatory and analgesic action, antidiabetic botanicals and the applications of African plant phytochemicals on reproductive, cardiovascular, and central nervous systems conditions. The final chapter covers the market and industry updates since the first edition published. "Medicinal Plant Research in Africa, 2 Ed." provides a complete overview of the main phytochemical principles present in the African flora and their pharmaceutical use. Pharmaceutical scientists, Ethnopharmacists, botanists, and medicinal chemists will benefit from the content organization and the inclusion of the most recent methods for structural identification of phytochemicals, pharmacological techniques, and data interpretation.

  • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

    • 1st Edition
    • Volume 291
    • English
    Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

  • Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

    Basics to Emerging Applications
    • 1st Edition
    • Ankit Jain + 2 more
    • English
    Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

  • The Potential of Cancer Biomarkers

    From Discovery to Clinical Application
    • 1st Edition
    • Pranav Kumar Prabhakar
    • English
    The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.

  • Terrestrial Biomes

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1st Edition
    • Germano Leão Demolin-Leite
    • English
    Terrestrial Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores the effects of anthropogenic activities on Earth’s terrestrial biomes, species, and climate. The book summarizes operational and potential monitoring tools to conserve or recover terrestrial biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies the challenges and threats to terrestrial organisms and connects them to real cases of conservation.This is an important resource for students, professors, researchers, and governmental and non-governmental organizations active in biodiversity conservation and climate change mitigation.

  • The Science of the Brain

    Function, Dysfunction and Disease
    • 1st Edition
    • Ari Rappoport
    • English
    The Science of the Brain: Function, Dysfunction and Disease delves into the intricate workings of the human brain, offering a groundbreaking examination of its complexities and the disorders that can arise when it malfunctions. This book, authored by a distinguished neuroscientist, unravels the mysteries of cognition, memory, and emotion while exploring how neurodegenerative diseases, mental health conditions, and brain injuries disrupt these processes. Designed to be accessible yet deeply informative, it bridges the gap between cutting-edge scientific research and real-world clinical applications, making it an invaluable resource for both professionals and curious readers.In addition to its comprehensive analysis of brain function, the book introduces readers to the latest innovations in neuroscience, including technological advancements in brain imaging and treatments. It also examines the ethical dilemmas posed by emerging technologies and their implications for society. With its blend of readability and scientific rigor, this work sheds light on the possibilities for future research and intervention, inspiring a deeper understanding of one of the most complex organs in the human body.

  • Imaging of Neurofluids, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-2
    • Nivedita Agarwal + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Nivedita Agarwal and Anja van der Kolk bring their considerable expertise to the topic of Imaging of Neurofluids. Top experts discuss key topics in this burgeoning field to create a primer ideal for neuroradiologists and radiologists. Topics include the basics of neurofluids, animal models, gadolinium-based imaging, perfusion-based imaging, diffusion tensor imaging, PET imaging, and specific articles on perivascular spaces, parasagittal dura mater and meningeal lymphatics, amyloid-related imaging abnormalities, and Alzheimer’s disease.

  • Emerging Fuzzy Intelligent Systems for Smart Healthcare Management

    Applications of Disc q-Rung Orthopair Fuzzy Sets
    • 1st Edition
    • Shahzaib Ashraf + 3 more
    • English
    Emerging Fuzzy Intelligent Systems for Smart Healthcare Management: Applications of Disc q-Rung Orthopair Fuzzy Sets presents comprehensive methodological frameworks and the latest empirical research findings concerning disc q-rung orthopair fuzzy operators, with a specific focus on their applications in smart technologies for healthcare management. The book solves a crucial problem by offering readers an invaluable opportunity to conduct a comparative analysis, contrasting the proposed methods with their existing knowledge base. Disc q-Rung Orthopair sets, being the generalization of q-Rung Orthopair fuzzy sets, which are, in turn, the generalization of Pythagorean fuzzy sets, extend the capabilities of handling uncertainty beyond conventional fuzzy sets.The authors strive to narrow the knowledge gap by clarifying the practical applications of disc q-rung orthopair fuzzy logic. In addition, it explores an enhanced version of q-Rung Orthopair Fuzzy Sets, specifically focusing on Disc q-Rung Orthopair Fuzzy Sets, introducing various types of operators. These operators play a crucial role in solving decision-making and optimization problems. A notable contribution is the development of a hybrid operator, termed as the Disc q-Rung Orthopair Fuzzy Hybrid Weighted Averaging/Geometric (D-qROFHWA/G) operator.

  • Adenoviral Vectors for Gene Therapy

    • 3rd Edition
    • David T. Curiel + 1 more
    • English
    Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, as platforms for gene therapy and gene editing, as well as for oncology approaches, making them class leading agents in the gene-advanced therapies arena.The fully updated and expanded third edition covers the basic biology of adenoviruses and highlights the potential use of adenoviral vectors for the treatment of disease, including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for veterinary applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine applications, and oncolytic adenoviruses for antitumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

  • Innovative Conservation Techniques and Perspectives

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1st Edition
    • Germano Leão Demolin-Leite
    • English
    Innovative Conservation Techniques and Perspectives: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores operational and potential monitoring tools to conserve and/or recover biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies operational, emerging, and proposed methods for land monitoring and management across the world’s biomes. This important resource on biodiversity is an ideal resource for students, professors, researchers, and both governmental and non-governmental organizations active in biodiversity conservation.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 126
    • English
    Advances in Clinical Chemistry, Volume 126, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. Chapters in this new release include Internalization of Extracellular Tau Oligomers in Alzheimer’s Disease, Advances in Neurofilament Light Chain Analysis, Biomarkers of Endometriosis, Lupus Nephritis II: Treatment and Monitoring, and Emerging Biomarkers in Type 2 Diabetes Mellitus, Coagulopathy Prediction in Traumatic Brain Injury.

  • Flow Cytometry in Immuno-oncology

    • 1st Edition
    • Volume 195
    • English
    Flow Cytometry in Immuno-oncology, Volume 173 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, Basic principles of Flow cytometry in immuno-oncology, Good practice and methods for flow cytometry in immuno-oncology, Automated flow cytometry in immuno-oncology, Flow cytometric analysis of Tregs in solid tumors, Multiparametric analysis of Tumor infiltrating lymphocytes in solid tumors, Analysis of tumor-infiltrating immune cells in intracranial glioblastoma, Assessing chromosomal abnormalities in leukemias by Imaging flow cytometry, Flow cytometric analysis of cellular alkaline phosphatase in acute myeloid leukemia, and much more.

  • Biomedical and Clinical Cryogenics

    Theory, Current Technology Advances, and Future Perspectives
    • 1st Edition
    • Hussam Jouhara + 1 more
    • English
    Biomedical and Clinical Cryogenics: Theory, Current Technology Advances, and Future Perspectives presents the complexity of cryogenic engineering applications in both medical and clinical settings. The book demonstrates both a comprehensive and up-to-date understanding of ongoing, new applications and their cutting-edge breakthroughs within the biomedical engineering sector. It contributes to the rapidly emerging and expanding field of cryogenics by emphasizing the complexity of associated mechanisms and interactions. In six chapters, this book collects, investigates, and critically discusses state-of-the-art cryogenic practices, along with the challenges and perspectives of the most common applications.By using cryogenics sciences, new milestones in medicine and human-life expectancy can be significantly increased. Since this is highly interdisciplinary content, this book is a valuable resource for biomedical engineers, health professionals, scientists, researchers, students, and all those who wish to broaden their knowledge in the allied field.

  • Drug Delivery Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Drug Delivery Landscape in Cancer Research examines the combined impact of prevention, diagnosis, and treatment of cancer. With a strong focus on the status, challenges, and prospects of cancer drug delivery technology, the book examines clinical translation-related knowledge and the development of different organ related cancers. In 22 chapters, it describes current and new drug delivery systems in twenty different cancers and gives insights into drug delivery strategies and tumor microenvironment management in oral and ocular cancers. This book is a timely and valuable resource for health professionals, scientists, researchers, health practitioners, students, and anyone who wants to broaden their knowledge.

  • Revolutionizing Drug Discovery: Cutting-Edge Computational Techniques

    • 1st Edition
    • Volume 103
    • English
    Revolutionizing Drug Discovery: Cutting-Edge Computational Techniques is an essential guide for professionals, researchers, and students in the pharmaceutical and biotech industries, providing an in-depth look at how computational methods transform drug development. This book explores advanced tools like molecular modeling, machine learning, and AI-driven design, which accelerate drug discovery, enhance target identification, and improve clinical outcome predictions. Through real-world applications and case studies, readers gain practical insights into the benefits of computational approaches in managing data, optimizing leads, and predicting drug efficacy and safety. Emphasizing a multidisciplinary approach, it bridges chemistry, biology, and informatics, addressing both the technical and ethical dimensions of these innovations. This book is a roadmap to the future of medicine, revealing how computational advancements are reshaping the landscape of drug discovery.

  • Diagnostic Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Diagnostic Landscape in Cancer Landscape examines the combined impact of prevention, diagnosis, and treatment of cancer. With a strong focus on the status, challenges, and prospects of diagnostic tools and technology, the book also examines the clinical translation-related knowledge and prognosis of different organ related cancers. In 22 chapters, the book describes current and new diagnostic tools in twenty different cancers and explores how innovations in the cancer diagnostic space could make cancer screening and early detection more straightforward.This book is a timely and valuable resource for health professionals, scientists, researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Nutrition and Physiology of Fish and Shellfish

    Feed Regulation, Metabolism, and Digestion
    • 1st Edition
    • Vikas Kumar
    • English
    Nutrition and Physiology of Fish and Shellfish: Feed Regulation, Metabolism and Digestion is a solid reference on the most recent advances and fundamental subjects in nutrient metabolism, intestinal transport and physiology of taste in fish. The book covers the known nutrient requirements and deficiency effects for different fish, along with information on the digestion and metabolism of nutrients and energy. It discusses nutrient sources and preparation of practical and research feeds and provides directions for conducting fish nutrition and feeding experiments. Other sections address current topics of interest to researchers and nutritionists in aquaculture research and the feed and allied industry. Nutrition and Physiology of Fish and Shellfish: Feed Regulation, Metabolism and Digestion is written by an international group of experts and contains fresh approaches of both classical and modern concepts of animal nutrition. All chapters clearly provide the essential literature related to the principles of fish nutrition and physiology that will be useful for academic researchers, those working professionally in aquaculture industries, and for graduate level students and researchers.

  • Nano-bioinoculants

    Smart Tools for Modern Agriculture
    • 1st Edition
    • Parul Chaudhary + 3 more
    • English
    Nano-bioinoculants: Smart Tools for Modern Agriculture discusses the interactions between nanoparticles and soil–plants–microbio... systems in a single-volume book designed to guide improvements in sustainable agriculture i.e. plant production and soil health. Past practices for the application of pesticides and chemical fertilizers have reduced the beneficial microbial diversity and soil fertility essential for optimal crop yield and overall plant health. As a result, developing innovative approaches to plant/soil health maintenance, bioremediation process, and stress management is advancing. Plant protection methods are increasingly being tailored to improve sustainable precision results, reduce environmental impact, and to target specific plant health challenges. Nano-bioinoculants: Smart Tools for Modern Agriculture explains nanoparticles and beneficial microbes and their impact on soil microbiomes, soil fertility restoration, remediation of contaminated soil, and plant health. It also highlights nanoparticles and bioinoculants in stress management, plant growth, and productivity, as well as covering the potentially toxic effect of nanoparticles on humans and the environment. This volume in the Nanomaterial-Plant Interactions series explores the potential of nano-biotechnology for better agronomic performance and sustainability.

  • Biodiversity, Bioengineering, and Biotechnology of Fungi

    • 1st Edition
    • Chakravarthula Manoharachary + 3 more
    • English
    Biodiversity, Bioengineering, and Biotechnology of Fungi examines various fungi genera and their biotechnological applications. The book covers the most common genera of fungi, their structure, their taxonomy, the maintenance and organization of a permanent study collection with associated databases, and their application in diverse sectors including industrial applications in the food, environment, bioenergy, biorefinery, and biopharma sectors.Compiled by an international team of fungal biologists, Biodiversity, Bioengineering, and Biotechnology of Fungi provides a wealth of information particularly on the diversity of fungal genera and their biotechnological contributions. The book is a valuable resource for scientists, researchers, health practitioners, nutritionists, industry professionals, advanced students, and all those who wish to broaden their knowledge in the allied field.

  • Nanocarriers Based Colon Targeting

    Design, Development, Mechanism and Case Studies
    • 1st Edition
    • Lalit Kumar + 1 more
    • English
    Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies unveils a groundbreaking exploration of nanotechnology’s potential in revolutionizing drug delivery for colon-related ailments. Today, an array of colonic diseases, including colorectal cancer, colonic polyps, ulcerative colitis, and inflammatory bowel syndrome, pose significant medical challenges. Conventional methods to deliver drugs to this system prove difficult, with limited efficacy and notable side effects. This book delves into the intricate complexities of colonic diseases, their pathophysiology, and epidemiology to support pharmaceutical scientists in designing better drug delivery systems. Providing a comprehensive overview of the area, the chapters elucidate diverse targeting strategies, from time-dependent to microbiota-based drug delivery systems, and explore receptor-based and magnetically assisted delivery mechanisms. Case studies dissected the working mechanisms behind polymeric nanoparticles, polymersomes, polymeric micelles, solid lipid nanoparticles, and other nanocarrier systems tailored for colon targeting. Additionally, this book explores cuttingedge topics such as gold nanoparticles, supra-magnetic iron oxide nanoparticles, and protein–peptide-base... nanoparticles, highlighting their mechanisms, applications, and potential toxicities. Merging an overview of colonic pathophysiology with in-depth reviews of each nanomaterial used for drug delivery and practical case studies, Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies is a complete reference for pharmaceutical scientists involved in elevating drug delivery precision and therapeutic efficacy in this organ system. Toxicologists, material scientists, research physicians, and regulators can also benefit from the case studies developed by expert authors.

  • Integrated Pathy

    Re-envisioning Healthcare and Wellness Using India as a Case Study
    • 1st Edition
    • Acharya Balkrishna
    • English
    Integrated Pathy: Re-envisioning Healthcare and Wellness Using India as a Case Study brings together the best holistic treatments tailored to improve patient care. The book focuses on health and healing rather than disease and treatment. Instead of following the fragmented approach of modern and contemporary line, or more specifically, the allopathic regime of treatments, the book views patients as a complete entity inclusive of minds, spirits, and bodies, and includes these dimensions in diagnosis and treatment to provide a custom healing regime. Attention is paid to inherent lifestyle factors such as diet, exercise, quality of rest, sleep, and the nature of relationships.Reader... will find a fresh perspective on revitalizing traditional indigenous practices and the reliability and efficacy of so-called traditional and alternative therapies, both of which will undoubtedly contribute to the advancement of the ecosystem of research in this field.

  • Nanotechnology of Veterinary Medicine and Livestock Production

    • 1st Edition
    • PK Gupta
    • English
    Nanotechnology of Veterinary Medicine and Livestock Production compiles the most impactful emerging research on the use of nanotechnology in animal sciences. This novel data, methods, and technologies will improve animal health, welfare, production, and nutrition, and will have implications for the future of human health, disease control, and food safety. Authored by a renowned animal toxicologist, this book introduces the history of nanotechnology in animal science before delving into its interdisciplinary applications. Central chapters explore nanomaterials in animal disease treatment, nanovaccine development, nanotechnology in animal nutrition and production, and applications for antibiotic-based therapies.Concluding chapters summarize the risks of these novel technologies, their challenges, and opportunities in various animal science sectors. This is an essential resource for researchers, clinicians, and animal scientists seeking information on cutting edge nano- and biotechnological advancements.

  • Essentials of Clinical Neurophysiology

    • 4th Edition
    • Karl E. Misulis + 1 more
    • English
    Up-to-date and easy to read, Essentials of Clinical Neurophysiology, Fourth Edition, details the basics of normal and abnormal neurologic function and provides authoritative clinical guidance on performing and interpreting today's full range of neurophysiologic studies. Drs. Karl E. Misulis and Thomas C. Head cover recent advances in technology as well as changes in training and practice patterns for EEG, EMG, EP, intraoperative monitoring, sleep studies, and autonomic testing. Offering a practical overview of this complex field, this one-stop resource is an excellent tool for board review and preparation.

  • Pharmacology, Physiology, and Practice in Obstetric Anesthesia

    • 1st Edition
    • Alan D. Kaye + 1 more
    • English
    Pharmacology, Physiology, and Practice in Obstetric Anesthesia provides all the essentials of obstetric anesthesia in a straightforward, user-friendly format that avoids encyclopedic language and lengthy discussions, and is inclusive of other healthcare specialties and subspecialties including obstetrics, neonatal care, and more. Coverage spans the essentials of obstetrics as well as overlooked issues including obstetric pharmacology and physiology safe practice strategies, clinical concepts for vaginal delivery and C-section, high-risk pregnancy states and management of the complicated parturient, complications and medicolegal, fetus and newborn considerations, and guidelines, standards and statements related to obstetric anesthesia.Pharmacol... Physiology, and Practice in Obstetric Anesthesia is the perfect reference for an interdisciplinary group of health professionals, policymakers, and researchers working and training in the field of obstetric anesthesiology

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