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Elsevier

Books in Life sciences

  • Non-Bovine Milk and Milk Products

    • 1st Edition
    • Effie Tsakalidou + 1 more
    • English
    Non-Bovine Milk and Milk Products presents a compiled and renewed vision of the knowledge existing as well as the emerging challenges on animal husbandry and non-cow milk production, technology, chemistry, microbiology, safety, nutrition, and health, including current policies and practices. Non-bovine milk products are an expanding means of addressing nutritional and sustainable food needs around the world. While many populations have integrated non-bovine products into their diets for centuries, as consumer demand and acceptance have grown, additional opportunities for non-bovine products are emerging. Understanding the proper chain of production will provide important insight into the successful growth of this sector. This book is a valuable resource for those involved in the non-cow milk sector, e.g. academia, research institutes, milk producers, dairy industry, trade associations, government, and policy makers.

  • Tissue Engineering Made Easy

    • 1st Edition
    • Farhana Akter
    • English
    Tissue Engineering Made Easy provides concise, easy to understand, up-to-date information about the most important topics in tissue engineering. These include background and basic principles, clinical applications for a variety of organs (skin, nerves, eye, heart, lungs and bones), and the future of the field. The descriptions and explanations of each topic are such that those who have not had any exposure to the principles and practice of tissue engineering will be able to understand them, and the volume will serve as a source for self-teaching to get readers to a point where they can effectively engage with active researchers.

  • Wound Healing Biomaterials - Volume 2

    Functional Biomaterials
    • 1st Edition
    • Magnus Ã…gren
    • English
    Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care.

  • Atlas of Stored-Product Insects and Mites

    • 1st Edition
    • David Hagstrum
    • English
    No other reference offers such an extensive hands-on guide to the most common stored-product pests. Atlas of Stored-Product Insects and Mites includes photographs and summary information for each of the 235 stored product insect species. Summary information includes common names, synonyms for scientific names, records of geographic distribution, suitability of commodities as insect food and commodity infestation, literature citations for life history studies and a list of natural enemies. Similar summary information is provided for 280 species of mites (Acari) reported to be associated with stored products. The high quality photographs and summary information make this reference essential to the fast and accurate specific identification needed for effective pest management. The authors also cover the tools and information that should be considered when developing a pest management program and provide reference sources for additional information on pest management. Atlas of Stored-Product Insects and Mites will make solving stored-product pest problems faster and easier making this an essential desk reference for anyone working with stored-product insects or mites. Special features High quality color photographs for 235 species of stored product insects Common names and synonyms for 235 insect and 280 mite species Suitability of 537 commodities as food for 84 stored product insect species Summarizes 15,611 infestation records for 1010 commodities reported in the literature References for life history studies of insect and mite species Geographic distribution of each species List of natural enemies Discussion of tools and information needed for pest management An essential reference for: Extension personnel Food industry sanitarians Food industry managers Legislators Pest management professionals Pest management consultants Plant quarantine inspectors Regulators Seed technologists Stored-product entomologist Stored-product acarologists Students Urban entomologists

  • DNA Replication Across Taxa

    • 1st Edition
    • Volume 39
    • English
    DNA Replication Across Taxa, the latest volume in The Enzymes series summarizes the most important discoveries associated with DNA replication.

  • Developing Therapeutics for Alzheimer's Disease

    Progress and Challenges
    • 1st Edition
    • Michael S. Wolfe
    • English
    Developing Therapeutics for Alzheimer's Disease: Progress and Challenges provides a thorough overview of the latest advances toward the development of therapeutics for Alzheimer’s disease, along with the major hurdles that still must be overcome and potential solutions to these problems. Despite the lack of progress toward developing therapeutics that can slow or stop the progression of this disease, important discoveries have been made and many promising approaches are advancing in preclinical studies and clinical trials. This book outlines the special challenges related to specific targets and approaches, while presenting a realistic, comprehensive and balanced view of drug discovery and development in this area. Written by international leaders in the field, the book assesses prospects for the emergence of effective agents and allows readers to better understand the challenges, failures, and future potential for research in Alzheimer’s disease. This book is a valuable resource to academic scientists carrying out translational research in Alzheimer’s disease, industrial scientists engaged in Alzheimer's drug discovery, executives in biopharmaceutical companies making strategic decisions regarding the direction of internal research and potential outside partnerships, and graduate-level students pursuing courses on Alzheimer's therapeutics.

  • Visualizing RNA Dynamics in the Cell

    • 1st Edition
    • Volume 572
    • English
    Methods in Enzymology: Visualizing RNA Dynamics in the Cell continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods visualizing RNA dynamics in the cell, and includes sections on such topics as identification of RNA cis-regulatory sequences, IRAS, IMAGEtags, MERFISH, plant RNA labeling using MS2, and visualization of 5S dynamics in live cells using photostable corn probe.

  • Genetics of Monogenic and Syndromic Obesity

    • 1st Edition
    • Volume 140
    • English
    Genetics of Monogenic and Syndromic Obesity is the latest volume in the Progress in Molecular Biology and Translational Science series.

  • Encapsulations

    • 1st Edition
    • Volume 2
    • Alexandru Grumezescu
    • English
    Encapsulations, a volume in the Nanotechnology in the Agri-Food Industry series,presents key elements in establishing food quality through the improvement of food flavor and aroma. The major benefits of nanoencapsulation for food ingredients include improvement in bioavailability of flavor and aroma ingredients, improvement in solubility of poor water-soluble ingredients, higher ingredient retention during production process, higher activity levels of encapsulated ingredients, improved shelf life, and controlled release of flavor and aroma. This volume discusses main nanoencapsulation processes such as spray drying, melt injection, extrusion, coacervation, and emulsification. The materials used in nanoencapsulation include lipids, proteins, carbohydrates, cellulose, gums, and food grade polymers. Applications and benefits of nanoencapsulation such as controlled release, protections, and taste masking will be explained in detail.

  • Flavor

    From Food to Behaviors, Wellbeing and Health
    • 1st Edition
    • Patrick Etiévant + 3 more
    • English
    Flavor: From Food to Behaviors, Wellbeing and Health is the first single-volume resource focused on the different mechanisms of flavor perception from food ingestion, to sensory image integration and the physiological effects that may explain food behaviors. The information contained is highly multidisciplinary, starting with chemistry and biochemistry, and then continuing with psychology, neurobiology, and sociology. The book gives coherence between results obtained in these fields to better explain how flavor compounds may modulate food intake and behavior. When available, physiological mechanisms and mathematical models are explained. Since almost half a billion people suffer from obesity and food related chronic diseases in the world, and since recent research has investigated the possible roles of pleasure linked to the palatability of food and eating pleasure on food intake, food habits, and energy regulation, this book is a timely resource on the topic. This book links these results in a logical story, starting in the food and the food bolus, and explaining how flavor compounds can reach different receptors, contribute to the emergence of a sensory image, and modulate other systems recognized as controlling food intake and food behavior. The influence of age, physiological disorders, or social environments are included in this approach since these parameters are known to influence the impact of food flavor on human behavior.

  • Big on Bk

    Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels
    • 1st Edition
    • Volume 128
    • English
    Big on Bk: Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into this area. It reviews current knowledge and understanding, and also provides a starting point for researchers and practitioners entering the field.

  • Peanuts: Processing Technology and Product Development

    • 1st Edition
    • Qiang Wang
    • English
    Peanuts: Processing Technology and Product Development provides an overall review of the latest peanut and peanut-related research development worldwide, including not only peanut production and processing progress, but also peanut-related product (oil, protein) production technologies, and by-products utilization technologies (peptides, polyphenol, polysaccharide, and dietary fiber). The book focuses on technology practicability, and all the technologies introduced, have been partly or fully applied. It is a valuable book and important reference for technicians and R and D persons in the peanut processing industry, and can also be used as a reference book for professional teaching and scientific research in the field of food science and engineering.

  • Wound Healing Biomaterials - Volume 1

    Therapies and Regeneration
    • 1st Edition
    • Magnus Ã…gren
    • English
    Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials.

  • Genetic Toxicology Testing

    A Laboratory Manual
    • 1st Edition
    • Ray Proudlock
    • English
    Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 325
    • English
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology, and includes articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

  • Advances in Immunology

    • 1st Edition
    • Volume 131
    • English
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • Haemonchus Contortus and Haemonchosis – Past, Present and Future Trends

    • 1st Edition
    • Volume 93
    • English
    Haemonchus Contortus and Haemonchosis – Past, Present and Future Trends, the latest in the Advances in Parasitology series first published in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. The 2014 impact factor is 6.226.

  • The Stability and Shelf Life of Food

    • 2nd Edition
    • Persis Subramaniam + 1 more
    • English
    The second edition of The Stability and Shelf-life of Food is a fully revised and thoroughly updated edition of this highly-successful book. This new edition covers methods for shelf-life and stability evaluation, reviewing the modelling and testing of the deterioration of products as well as the use of sensory evaluation methods for testing food spoilage. The first part of the book focuses on deteriorative processes and factors influencing shelf-life, covering aspects such as chemical deterioration, physical instability and microbiological spoilage. The effects of process and packaging on the stability and shelf-life of products are also covered in this part. Part Two reviews the methods for shelf life and stability evaluation. These include sensory evaluation methods and instrumental methods to determine food quality deterioration. The final section of the book covers stability of important ingredient categories, from oils and fats, to beverages such as beer, wine, coffee and fruit juices, in addition to bakery products and meats. With updated chapters reflecting advances made in the field and with the addition of new chapters covering the stability and shelf-life a variety of products, this new edition will provide the latest research for both academics working in the field of food quality as well as providing essential information for food scientists working in industry.

  • The Evolution of the Immune System

    Conservation and Diversification
    • 1st Edition
    • Davide Malagoli
    • English
    The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors.

  • Thresholds of Genotoxic Carcinogens

    From Mechanisms to Regulation
    • 1st Edition
    • Takehiko Nohmi + 1 more
    • English
    Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even at very low levels. This policy is frequently called into question as humans possess a number of defense mechanisms including detoxication, DNA repair, and apoptosis, meaning there is a threshold at which these genotoxic carcinogens take action. The book examines these potential thresholds, describing the potential cancer risks of daily low-level exposure, the mechanisms involved (such as DNA repair, detoxication, translesion DNA synthesis), chemical and statistical methods of analysis, and the ways in which these may be utilized to inform policy. Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation is an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation.

  • Linked by Blood: Hemophilia and AIDS

    • 1st Edition
    • David Green
    • English
    Linked by Blood: Hemophilia and AIDS recounts the factors responsible for the widespread infection of people with hemophilia by Human Immunodeficiency Virus (HIV)-contaminated blood and offers a prescription for addressing the challenges of future viral epidemics. The book describes the impact of AIDS on people with hemophilia, their families, and caregivers. The collection, processing, and distribution of blood in the early years of the HIV epidemic are described, including the failure of regulatory agencies to promulgate effective rules to safeguard the blood supply. The contributions of individuals and organizations that mitigated the epidemic are recognized. Linked by Blood presents recommendations for addressing the myriad medical, social, and economic challenges posed by blood-borne viral infections (AIDS, Ebola, MERS) that periodically sweep through large segments of our population.

  • Continuous Issues in Numerical Cognition

    How Many or How Much
    • 1st Edition
    • Avishai Henik
    • English
    Continuous Issues in Numerical Cognition: How Many or How Much re-examines the widely accepted view that there exists a core numerical system within human beings and an innate ability to perceive and count discrete quantities. This core knowledge involves the brain’s intraparietal sulcus, and a deficiency in this region has traditionally been thought to be the basis for arithmetic disability. However, new research findings suggest this wide agreement needs to be examined carefully and that perception of sizes and other non-countable amounts may be the true precursors of numerical ability. This cutting-edge book examines the possibility that perception and evaluation of non-countable dimensions may be involved in the development of numerical cognition. Discussions of the above and related issues are important for the achievement of a comprehensive understanding of numerical cognition, its brain basis, development, breakdown in brain-injured individuals, and failures to master mathematical skills.

  • Extracellular Matrix-derived Implants in Clinical Medicine

    • 1st Edition
    • Daniel L Mooradian
    • English
    Extracellular Matrix-Derived Implants in Clinical Medicine comprehensively covers the emergence of tissue engineering and regenerative medicine over the past few decades, along with discussions of continuous funding and research. The book provides a state-of-the-art review of this increasingly important technology and how it is translating from bench to bedside. Part One of the book looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological, while Part Two examines the challenges in harvesting, processing, and manufacturing of extracellular matrices, with a final section reviewing the international regulatory environment and economics of tissue-based products.

  • Clinical Challenges in Therapeutic Drug Monitoring

    Special Populations, Physiological Conditions and Pharmacogenomics
    • 1st Edition
    • William Clarke + 1 more
    • English
    Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 48
    • Marc Naguib
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. This volume makes another important contribution to the development of the field by presenting theoretical ideas and research findings to professionals studying animal behavior and related fields.

  • Developing Food Products for Consumers with Specific Dietary Needs

    • 1st Edition
    • Steve Osborn + 1 more
    • English
    Developing Food Products for Customers with Specific Dietary Needs explains the process for developing foods for customers who have specific dietary needs, further shining a light on the number of increasing medical conditions related to food intake that have emerged in the past few decades. From increased fat and sugar intake leading to higher levels of obesity, to greater levels of coeliac disease, the ingredients and nutritional content of food is becoming more and more important. Additionally, consumers are following particular diets for many different reasons, be it health related, or for religious or moral reasons. The first part of the book looks, in detail, at the organizational structure required within a company to allow for the development of food products which meet the needs of these customers, while the second part presents a number of case studies highlighting the development of food products for various dietary requirements. Precise coverage includes section on the development of low-sodium, low-sugar, low-fat, and low-carbohydrate products with the aim of producing healthier foods, as well as the development of organic and vegetarian products for consumers who are following diets for personal reasons. The potential solutions for developing foods for customers who have specific dietary needs are likely to include both ingredients and technology developments. The ingredients area includes simple reductions as well as replacement strategies, whilst technology will be applied to both the ingredient itself and the host food product. All are aimed at maintaining the product quality as perceived by the customer.

  • The Gut-Brain Axis

    Dietary, Probiotic, and Prebiotic Interventions on the Microbiota
    • 1st Edition
    • Niall Hyland + 1 more
    • English
    The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders.

  • Novel Approaches of Nanotechnology in Food

    • 1st Edition
    • Volume 1
    • Alexandru Grumezescu
    • English
    Novel Approaches of Nanotechnology in Food, a volume in the Nanotechnology in the Agri-Food Industry series, represents a summary of the most recent advances made in the field of nanostructured materials that have significant impact on the agri-food industry. Because the current food market needs innovation, nanotechnology coupled with novel interdisciplinary approaches and processing methods has enabled important advances that have the potential to revolutionize agri-food sector. Nanotechnology can serve to resolve challenges faced by the food and bioprocessing industries for developing and implementing systems that can produce qualitative and quantitative foods that are safe, sustainable, and ecofriendly. This book is a valuable resource for scientists, researchers, and engineers in food science and biotechnology fields, as well as students who want information on cutting-edge technologies.

  • Healthgrain Methods

    Analysis of Bioactive Components in Small Grain Cereals
    • 1st Edition
    • Peter Shrewry
    • English
    The explosion of interest around the health benefits of whole grains has led to a new focus on the bioactive components of cereals, including their location and physiological effects. Grains are an important source of minerals (notably selenium, iron and zinc) and vitamins, such as folate. These nutrients are often degraded or removed by the milling or polishing of the grain to provide refined products. Measurements of these components require methodologies for analysis that must be accurate and reproducible and that provide adequate samples to allow wide screening. The work of the 47 prominent international food scientists presented in this comprehensive volume is the direct result of the European Union’s Framework 6 HEALTHGRAIN program which focuses on the role of wholegrain cereals in reducing the risk of metabolic syndrome-related diseases. The development of routine analytical methods for this group of essential phytochemical and dietary fiber components will help food companies improve the health benefits of their products as well as their abilities to measure the bioactive ingredients in cereal-based foods.

  • Translational Neuroimmunology in Multiple Sclerosis

    From Disease Mechanisms to Clinical Applications
    • 1st Edition
    • Ruth Arnon + 1 more
    • English
    Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development.

  • Sex Differences in Physiology

    • 1st Edition
    • Gretchen Neigh + 1 more
    • English
    Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available.

  • Biochar Application

    Essential Soil Microbial Ecology
    • 1st Edition
    • T. Komang Ralebitso-Senior + 1 more
    • English
    Biochar Application: Essential Soil Microbial Ecology outlines the cutting-edge research on the interactions of complex microbial populations and their functional, structural, and compositional dynamics, as well as the microbial ecology of biochar application to soil, the use of different phyto-chemical analyses, possibilities for future research, and recommendations for climate change policy. Biochar, or charcoal produced from plant matter and applied to soil, has become increasingly recognized as having the potential to address multiple contemporary concerns, such as agricultural productivity and contaminated ecosystem amelioration, primarily by removing carbon dioxide from the atmosphere and improving soil functions. Biochar Application is the first reference to offer a complete assessment of the various impacts of biochar on soil and ecosystems, and includes chapters analyzing all aspects of biochar technology and application to soil, from ecogenomic analyses and application ratios to nutrient cycling and next generation sequencing. Written by a team of international authors with interdisciplinary knowledge of biochar, this reference will provide a platform where collaborating teams can find a common resource to establish outcomes and identify future research needs throughout the world.

  • Pediatric Brain Stimulation

    Mapping and Modulating the Developing Brain
    • 1st Edition
    • Adam Kirton + 1 more
    • English
    Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions.

  • Atlas of Histology of the Juvenile Rat

    • 1st Edition
    • George A Parker + 1 more
    • English
    Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42.

  • Congenital Heart Disease and Neurodevelopment

    Understanding and Improving Outcomes
    • 1st Edition
    • Christopher McCusker + 1 more
    • English
    Congenital Heart Disease and Neurodevelopment: Understanding and Improving Outcomes brings together the work of leading researchers from the U.K., Europe, and the U.S. to provide a comprehensive examination of the causes, risks, and neurodevelopmental and psychological outcomes in children with congenital heart disease. The book includes longitudinal studies which have tracked outcomes from birth through late childhood and explores the emergent phenotype and etiologies, risk, and protective factors that strengthen proposed models. Medical and surgical advances have meant that greater numbers of children with even the most severe congenital heart disease (CHD) now survive well into adulthood. Studies over the past 20 years have suggested certain neurodevelopmental and psychological features are common, with clinical interventions being internationally articulated. The U.K. Belfast Center has developed and evaluated unique early intervention programs to circumvent the common problems discerned and promote optimal adjustment and outcomes. The first edition of Congenital Heart Disease and Neurodevelopment: Understanding and Improving Outcomes describes these programs in detail and outlines promising results obtained by researchers worldwide. Such interventions, together with the U.S. consensus statement (Circulation, 2012) on neurodevelopmental screening, hold great promise for clinical interventions.

  • Functional Neuromarkers for Psychiatry

    Applications for Diagnosis and Treatment
    • 1st Edition
    • Juri D. Kropotov
    • English
    Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results.

  • Mustard Lung

    Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients
    • 1st Edition
    • Mostafa Ghanei + 1 more
    • English
    Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients brings together the details regarding pathophysiology, medication, and protective issues to provide a comprehensive look at health problems associated with sulfur mustard injury. It provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function. By providing guidelines and approaches for the diagnosis, pathogenesis, and treatment of SM injury cases, this book is helpful for a wide range of medical researchers and clinicians. For decades, chemical respiratory disorders were diagnosed and managed traditionally similar to other chronic respiratory diseases. However, the exact nature of chemical respiratory disorders is different and needs to be treated as such.

  • Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

    • 1st Edition
    • Carlo Sala + 1 more
    • English
    Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms.

  • Advances in Bacterial Electron Transport Systems and Their Regulation

    • 1st Edition
    • Volume 68
    • Robert K. Poole
    • English
    Advances in Microbial Physiology: Advances in Bacterial Electron Transport Systems and Their Regulation, the latest volume in the Advances in Microbial Physiology series, continues the long tradition of topical and important reviews in microbiology, with this latest volume focusing on the advances in bacterial electron transport systems and their regulation.

  • Advances in Pathobiology and Management of Paget’s Disease of Bone

    • 1st Edition
    • Sakamuri V. Reddy
    • English
    Advances in Pathobiology and Management of Paget’s Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget’s disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget’s disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.

  • Pine Bark Beetles

    • 1st Edition
    • Volume 50
    • English
    Pine Bark Beetles, the latest release in the Advances in Insect Physiology series, provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists.

  • Encyclopedia of Immunobiology

    • 1st Edition
    • Michael J.H. Ratcliffe
    • English
    Encyclopedia of Immunobiology, Five Volume Set provides the largest integrated source of immunological knowledge currently available. It consists of broad ranging, validated summaries on all of the major topics in the field as written by a team of leading experts. The large number of topics covered is relevant to a wide range of scientists working on experimental and clinical immunology, microbiology, biochemistry, genetics, veterinary science, physiology, and hematology. The book is built in thematic sections that allow readers to rapidly navigate around related content. Specific sections focus on basic, applied, and clinical immunology. The structure of each section helps readers from a range of backgrounds gain important understanding of the subject.

  • Mixolab

    A New Approach to Rheology
    • 1st Edition
    • Arnaud Dubat
    • English
    Publishing high-quality food production applications handbooks is a hallmark of AACCI PRESS and Mixolab: A New Approach to Rheology is no exception. Increasing consumer demand for quality foods with superior nutritional value makes innovative tools like the Mixolab of increasing interest to food developers and producers. Operators, breeders, millers, researchers, product developers, formulators, and bakers will find answers to their questions, along with guidelines for maximizing the use of the Mixolab for a wide range of applications. Gaining a better understanding of the instrument's capabilities will assist in discovery of novel uses by both research and production professionals. Key Features: Technical description of the Mixolab and comparison with existing devices Coverage of durum wheat, rice, corn, buckwheat, and other cereals Specific focus on gluten, starch, ingredients, and enzymes Influence of sugar, fats, and salt on dough rheology International comparisons of HACCP experiences Table of uses for specific carbohydrates Descriptions of improved laboratory techniques Wheat testing for breeders An Essential Reference For: Additive manufacturers Bakers Breeders Enzyme manufacturers Millers Quality control laboratories Research laboratories Research and development centers Storage elevators Students Universities Yeast producers

  • Durum Wheat Chemistry and Technology

    • 2nd Edition
    • Michael Sissons
    • English
    The most extensive and comprehensive reference on durum wheat chemistry and technology ever available, this ambitious update to the first edition covers more diverse and interesting topics in a new expanded format. Forty-six contributors, each highly experienced and recognized as world authorities on durum wheat, provide the latest developments in scientific research and technology. All aspects of durum wheat are covered, from agronomy and the chemical composition of the grain, to the latest industrial approaches to processing durum wheat, as well as food safety and quality assurance issues. Expanded to include new topics like functional pasta, grain safety, and biotechnology, along with practical and applied information including a table of uses for specific carbohydrates, descriptions of improved laboratory techniques, and international comparisons of HACCP experiences, Durum Wheat: Chemistry and Technology, Second Edition is a must-have reference for professionals, students, and researchers inside and outside the field who want to learn about durum wheat technology and chemistry. New and Revised Topics Include: Agronomy of durum wheat production Pasta made from non-traditional raw materials: technological and nutritional aspects Grain safety assurance, including impacts on durum wheat trading Origin and distribution of durum wheat genetic diversity in the world Genetics and breeding of durum wheat Insect and mite pests and diseases of durum wheat Kernel components of technological value Vitamins, minerals, and nutritional value of durum wheat Durum wheat milling Manufacture of pasta products Other traditional durum derived products Methods used to assess and predict quality of durum wheat, semolina, and pasta Grading factors impacting on durum wheat and processing quality Grain safety assurance including impacts on durum wheat trading Marketing perspectives in the durum wheat trade Special Features: Detailed figures outlining the processes used to manufacture durum products International comparisons of HACCP experiences Table of uses for specific carbohydrates Descriptions of improved laboratory techniques Extensive bibliography An Essential Reference For: Scientists and researchers in agriculture and plant biology Professionals in the food industry who are processing durum wheat (millers, pasta makers, grain handling companies, and grain buyers) Government regulators Food scientists and technologists developing products using durum wheat Plant breeders University lecturers in agricultural science and plant biology Professionals who market wheat Nutritionists and medical practitioners interested in the impacts of food ingredients on human healthStudents Scientific libraries and their patrons

  • Controversies In Diabetic Neuropathy

    • 1st Edition
    • Volume 127
    • English
    This latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field.

  • Genetics and Molecular Biology of Entomopathogenic Fungi

    • 1st Edition
    • Volume 94
    • English
    Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions, This thematic volume focuses on the advances and the future potential of the rapidly growing field of entomopathogenic fungi. With a focus on the genetics and molecular biology behind the progress, techniques developed to study all aspects of these fungi will be highlighted, and topics will span from systematics of fungi to how a fungus infects an insect and how that insect responds.

  • Agricultural Law and Economics in Sub-Saharan Africa

    Cases and Comments
    • 1st Edition
    • Frederick Owusu Boadu
    • English
    Agricultural Law in Sub-Saharan Africa: Cases and Comments introduces the subject of agricultural law and economics to researchers, practitioners, and students in common law countries in Sub-Saharan Africa, and presents information from the legal system in Botswana, Gambia, Ghana, Lesotho, Malawi, Nigeria, Sierra Leone, South Africa, Swaziland, Tanzania, Zambia, and Zimbabwe. The law and economics approach entails the use of quantitative methods in research. This is consistent with the expectations in an applied economics field such as agricultural economics. Covering the general traditional law topics in contracts, torts, and property, the book goes further to introduce cutting-edge and region-relevant topics, including contracts with illiterate parties, contract farming, climate change, and transboundary water issues. The book is supported by an extensive list of reference materials, as well as study and enrichment exercises, to deepen readers’ understanding of the principles discussed in the book. It is a learning tool, first and foremost, and can be used as a stand-alone resource to teach the subject matter of agricultural law and economics to professionals new to the subject area as well as to students in law school, agricultural economics, economics, and inter-disciplinary classes.

  • Food Hygiene and Toxicology in Ready-to-Eat Foods

    • 1st Edition
    • Parthena Kotzekidou
    • English
    Food Hygiene and Toxicology in Ready-to-Eat Foods is a solid reference for anyone in the food industry needing to understand the complex issues and mechanisms of biological control and chemical hazards to ensure food safety. infectious and non-infectious contaminants in raw, minimally processed, and prepared foods are covered in detail, as well as effective measures to avoid foodborne infections and intoxications. The book is written by an international team of experts presenting the most up-to-date research in the field, and provides current applications and guidance to enhance food safety in the food industry. Strategies and recommendations for each food category include, among others, how to avoid cross-contamination of pathogens, the proper uses of antimicrobial coatings and spray cleanings of fresh produce, and acrylamide reduction during processing. leafy vegetables, fruit juices, nuts, meat and dairy products are some of the ready-to-eat foods covered.

  • Hematopoiesis

    • 1st Edition
    • Volume 118
    • English
    Hematopoiesis, the latest volume in the Current Topics in Developmental Biology, covers hematopoiesis, with contributions from an international board of authors. Its chapters provide a comprehensive set of reviews covering such topics as the regulation of blood stem cell development, epigenetic mechanisms controlling erythropoiesis, and regulatory RNAs/HSCs.

  • Clinical Research Computing

    A Practitioner's Handbook
    • 1st Edition
    • Prakash Nadkarni
    • English
    Clinical Research Computing: A Practitioner’s Handbook deals with the nuts-and-bolts of providing informatics and computing support for clinical research. The subjects that the practitioner must be aware of are not only technological and scientific, but also organizational and managerial. Therefore, the author offers case studies based on real life experiences in order to prepare the readers for the challenges they may face during their experiences either supporting clinical research or supporting electronic record systems. Clinical research computing is the application of computational methods to the broad field of clinical research. With the advent of modern digital computing, and the powerful data collection, storage, and analysis that is possible with it, it becomes more relevant to understand the technical details in order to fully seize its opportunities.

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