Receptors
Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
- 1st Edition - January 1, 1979
- Imprint: Pergamon
- Editor: J. Jacob
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 1 - 2 5 5 4 - 1
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 2 3 1 9 1 - 4
- eBook ISBN:9 7 8 - 1 - 4 8 3 1 - 5 7 9 6 - 2
Advances in Pharmacology and Therapeutics, Volume l: Receptors contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers… Read more
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Request a sales quoteAdvances in Pharmacology and Therapeutics, Volume l: Receptors contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of receptors, their pharmacology, and their therapeutic applications. Topics covered range from opiate receptors and their endogenous ligands to membrane receptors in eukaryotic cells. Applications of binding to pharmacological research are also discussed. This volume is comprised of 29 chapters and opens with an overview of the chemistry and biochemistry of pituitary endorphins, paying particular attention to the correlation between the analgesic potency, receptor binding properties, preferred solution conformation, and metabolic stability of natural and synthetic opioid peptides. The reader is then introduced to the biosynthesis and release of the enkephalins; opiate receptors and their endogenous ligands; denervation supersensitivity in skeletal muscle; and biochemistry and physiology of dopaminergic and beta-adrenergic receptors in mammalian central nervous system. The following chapters explore the role of guanylnucleotides in the regulation of hormonally stimulated adenylate cyclase; interactions of cholera toxin with cell membranes; problems in studying hormone receptor binding; and the mechanism of action of anti-hormones. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.
Introduction
Opiate Receptors and their Endogenous Ligands
Chemistry and Biochemistry of Pituitary Endorphins
Multiple Opiate Receptors
Pituitary Endorphins: Recent Progress
The Biosynthesis and Release of the Enkephalins
Opiate Receptors: A) Functional Heterogeneity Demonstrated with an Apparently Irreversible Naloxone Derivative
B) Regulation by Guanine Nucleotides
Opiate Receptors, their Endogenous Ligands and the Development of Tolerance/Dependence
Physiological and Pathophysiological Relevance of the Endogenous Ligands of the Opiate Receptors
Membrane Receptors in E ucaryotic Cells
Multiple Classes of Muscarinic Receptor Binding Sites in the Brain
Biophysical Aspects of Agonist Action at Frog Endplate
Some Observations on Denervation Supersensitivity in Skeletal Muscle
Structural and Functional Properties of the Acetylcholine-Regulator
Glutamate Receptors in Eucaryotes
Biochemistry and Physiology of Dopaminergic and Beta-Adrenergic Receptors in Mammalian Central Nervous System
Beta-Adrenergic Receptors in C6 Glioma Cells and Central Nervous System
Recent Studies on Opiate Receptors
The Role of Quanylnucleotides in the Regulation of Hormonally Stimulated Adenylate Cyclase
Catecholamine-Sensitive Adenylate Cyclase: Identification and Partial Characterization of Some of its Components
Interactions of Cholera Toxin with Cell Membranes
Hybridization of Hormone Receptors with Adenylate Cyclase Systems of Different Cells
Receptor Binding Studies of Beta-Adrenergic Receptors: New Insights into Activation and Desensitization of Adenylate Cyclase
Applications of Binding to Pharmacological Research
Control of Hormone Receptor Levels and Function
Problems in Studying Hormone Receptor Binding
Methodological Approach to Radioligand Binding Studies of Adrenergic Receptors
Main Lectures
Synaptic Receptor Proteolipids: Isolation and Molecular Biology
The Mechanism of Action of Anti-Hormones
Angiotensin Receptors
Index
- Edition: 1
- Published: January 1, 1979
- No. of pages (eBook): 304
- Imprint: Pergamon
- Language: English
- Paperback ISBN: 9781483125541
- Hardback ISBN: 9780080231914
- eBook ISBN: 9781483157962
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