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Elsevier

Books in Life sciences

  • Handbook of Advanced Chromatography /Mass Spectrometry Techniques

    • 1st Edition
    • Michal Holcapek + 1 more
    • English
    Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 12
    • 1st Edition
    • M. A. Hayat
    • English
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.

  • Staphylococcus aureus

    • 1st Edition
    • Alexandra Fetsch
    • English
    Staphylococcus aureus provides information on food borne outbreaks of disease and their impact on human health. It is for anyone interested in the features of the pathogen, and its food safety aspects, as well as its prevalence and possible control and eradication options. This is a practical reference for those in the food industry, but also includes some theoretical information useful for advising. The book introduces detailed features and molecular biology of the pathogen, as well as selective methods of detection, prevention and eradication essential for research. It covers methicillin-resistan... staphylococcus aureus for food related industries, information on genetic lineages, cell wall components, cell division machinery, molecular characterization, and capillary electrophoresis for detecting and characterizing staphylococcus aureus.

  • The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine

    • 1st Edition
    • Uri Galili
    • English
    The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.

  • Data Literacy

    How to Make Your Experiments Robust and Reproducible
    • 1st Edition
    • Neil Smalheiser
    • English
    Data Literacy: How to Make Your Experiments Robust and Reproducible provides an overview of basic concepts and skills in handling data, which are common to diverse areas of science. Readers will get a good grasp of the steps involved in carrying out a scientific study and will understand some of the factors that make a study robust and reproducible.The book covers several major modules such as experimental design, data cleansing and preparation, statistical analysis, data management, and reporting. No specialized knowledge of statistics or computer programming is needed to fully understand the concepts presented. This book is a valuable source for biomedical and health sciences graduate students andresearchers, in general, who are interested in handling data to make their research reproducibleand more efficient.

  • Northeast Pacific Shark Biology, Research and Conservation Part A

    • 1st Edition
    • Volume 77
    • English
    Northeast Pacific Shark Biology, Research and Conservation, Part A, Volume 77 highlights the biological attributes of, and the conservation efforts targeted at, populations of vulnerable sharks in the Northeastern Pacific Ocean bordering the west coast of the United States, one of the most economically and ecologically important oceanic regions in the world. Updates in this new volume include chapters on Biodiversity, Conservation and Life History of Northeastern Pacific Chondrichthyans, a Review of current genetic analyses of Northeast Pacific sharks and conservation implications, and a section on the Trophodynamics and ecological impacts of eastern North Pacific sharks.

  • miRNA and Cancer

    • 1st Edition
    • Volume 135
    • English
    miRNA and Cancer, Volume 135, the latest volume in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, and includes specific chapters on Non-coding RNAs as Biomarkers of Cancer, The Enigma of microRNA Regulation in Cancer, Animal Models to Study microRNA functions, Non-coding RNAs and Cancer, microRNAs in Cancer Susceptibility, ts-RNAs versus microRNAs, microRNAs and AML, and microRNAs and Epigenetics.

  • Genetically Engineered Foods

    • 1st Edition
    • Volume 6
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Genetically Engineered Foods, Volume 6 in the Handbook of Food Bioengineering series, is a solid reference for researchers and professionals needing information on genetically engineered foods in human and animal diets. The volume discusses awareness, benefits vs. disadvantages, regulations and techniques used to obtain, test and detect genetically modified plants and animals. An essential resource offering informed perspectives on the potential implications of genetically engineered foods for humans and society. Written by a team of scientific experts who share the latest advances to help further more evidence-based research and educate scientists, academics and government professionals about the safety of the global food supply.

  • Fe-S Cluster Enzymes Part A

    • 1st Edition
    • Volume 595
    • English
    Fe-S Cluster Enzymes, Part A, Volume 595 is the first of two volumes focused on Fe-S cluster enzymes. New topics of note in this series include Electrochemistry of Fe/S Proteins, Genetic, biochemical and biophysical methods for studying Fe-S proteins and their assembly, Fluorescent reporters to track Fe-S cluster assembly and transfer reactions, Mechanism-based strategies for structural characterization of radical SAM reaction intermediates, Purification and Characterization of Recalcitrant Cobalamin-Dependent Radical S-adenosylmethionine Methylases, A polymerase with potential: the Fe-S cluster in Human DNA Primase, In Vitro Studies of Cellular Iron-sulfur Cluster Biosynthesis, Trafficking and Transport, and Fe-S cluster Hsp70 Chaperones: the ATPase cycle and protein interactions.

  • Immunity and Inflammation in Health and Disease

    Emerging Roles of Nutraceuticals and Functional Foods in Immune Support
    • 1st Edition
    • Shampa Chatterjee + 2 more
    • English
    Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here.

  • FDA Warning Letters About Food Products

    How to Avoid or Respond to Citations
    • 1st Edition
    • Joy Frestedt
    • English
    FDA Warning Letters About Food Products: How to Avoid or Respond to Citations uses examples of FDA warning letters about food products as training tools to discuss important quality and manufacturing issues encountered by food companies around the world as they bring food products into the US market. Focused specifically on FDA warning letters surrounding new dietary ingredients and dietary supplements, the book first introduces FDA warning letters in general. Each chapter then focuses on specific issues identified, including HAACP/quality systems, imports/exports, food contact issues, etc. This book helps the food industry train professional team members (across the spectrum of experience levels) to avoid common issues often cited in warning letters. It serves both as an authoritative reference on the common types of warning letters issued to food companies today, and as a guide to best practices for food manufacturers.

  • Incorporating Cultures' Role in the Food and Agricultural Sciences

    • 1st Edition
    • Florence V. Dunkel
    • English
    Incorporating Cultures' Role in the Food and Agricultural Sciences addresses the practical needs of the professors, administrators and students who often face challenges of working together with Indigenous peoples with whom they have no prior experience. Missed communication, failed projects and unrealistic goals are daily realities. Academia and industry often encounter frustration in recruiting and retaining Native American students and other ethnicities. This text is a guide for anyone working in the food or agriculture disciplines or industries, particularly for those working with people of a culture different from one’s own. Comprehensive, full awareness of one’s own culture is a prerequisite for effective teaching and learning within another culture. This book is replete with stories, examples and peer-refereed journal articles to help build awareness. These stories, examples and articles from multiple voices are placed over a basic underlying framework that is summed up in the title of the book itself.

  • Sterol Regulation of Ion Channels

    • 1st Edition
    • Volume 80
    • English
    Sterol Regulation of Ion Channels, Volume 80, the latest in the Current Topics in Membranes series provides outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. Topics of note in this new release include Membrane structure and general mechanisms of sterol regulation of ion channels, the Regulation of ion channels by sterols as boundary lipids, the Differential effects of sterols on ion channels: specific vs. non-specific interactions, the Structural determinants of cholesterol-ion channels interactions, and the Regulation of Ca2+-sensitive K+ channels by cholesterol and bile acids via distinct channel subunits and sites, amongst other specialized chapters. The serial is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes

  • Comparative Anatomy and Histology

    A Mouse, Rat, and Human Atlas
    • 2nd Edition
    • Piper M. Treuting + 2 more
    • English
    The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease.

  • Methods in Tau Cell Biology

    • 1st Edition
    • Volume 141
    • English
    Methods in Tau Cell Biology, Volume 141, the latest release in the Methods in Cell Biology series, looks at methods involved in tau cell biology. Edited by leaders in the field, this volume provides proven, state-of-art techniques and relevant historical background and theory that aids researchers with tactics for efficient design and effective implementation of experimental methodologies. Topics of note in this updated volume include sections on Recombinant tau expression and purification, In vitro MT dynamics and MT ends, Methods related to investigating tau structure and MT bundling, Neurite outgrowth and retraction, and Methods related to studying tau fragmentation.

  • Understanding Plastics Recycling

    • 1st Edition
    • Natalie Rudolph
    • English
    Understanding Plastics Recycling shows the true and often-underestimated market potential of plastics recycling, with analysis from economic, ecological, and technical perspectives. It is aimed at both technical and non-technical readers, including decision makers in material suppliers, plastic product manufacturers, governmental agencies, educators, and anyone with a general interest in plastics recycling. An overview of waste handling systems with a focus on the U.S. market is provided. Different methods of waste handling are compared from both economic and ecological perspectives. Since plastic waste recycling is essential from an ecological point of view, common strategies and new approaches to both increase the recycling rate and improve recycling economically and technically are presented. This includes processing and material properties of recycled plastics. Finally, a worldwide outlook of plastic recycling is provided with analysis of additional worldwide markets, encompassing highly developed, fast-developing, and less developed countries.

  • The Complex Connection between Cannabis and Schizophrenia

    • 1st Edition
    • Michael T. Compton + 1 more
    • English
    The Complex Connection between Cannabis and Schizophrenia provides an in-depth overview of the current state of research into the role that cannabis plays in schizophrenia, covering both the pathophysiological and the pharmacological implications. It addresses the epidemiology of cannabis use and the risks associated with its use, the biological aspects of the drug, its effects on the brain and the pharmacological possibilities of using cannabidiol to treat schizophrenia. It is the only book on the market devoted exclusively to examining the links between this very commonly used (and misused) drug and a specific set of devastating psychiatric illnesses, providing a comprehensive guide to our current understandings of this relationship. Marijuana is the most commonly used illicit drug globally, and is becoming increasingly decriminalized and even legalized worldwide. Among the numerous mental-health concerns related to the drug, there is mounting evidence of an intricate link between cannabis use and schizophrenia and related psychotic disorders. At the same time, there is promising evidence to suggest that cannabidiol, one of the many compounds found in cannabis that activates the brain’s cannabinoid receptors, could prove to be an effective antipsychotic to treat schizophrenia.

  • Insect Epigenetics

    • 1st Edition
    • Volume 53
    • English
    Insect Epigenetics, Volume 53 provides readers with the latest interdisciplinary reviews on the topic. Updated chapters in this new release include Epigenetics in insects: Mechanisms, ecological outcomes, and evolutionary consequences, Nutrition and epigenetic change in insects, microRNAs in Drosophila insulin regulation, Epigenetic regulation of longevity in insects, Epigenetic influences on diapause, the Impact of parasites on epigenetics of their insect hosts, The molecular physiology of locust swarming behavior, The future of environmental epigenetics: insights using the clonal water-flea model, and. Epigenetics – A hidden target of insecticides. Led by volume editor Heleen Verlinden, this is an essential reference source for entomologists, zoologists, geneticists and insect chemists.

  • The International Society for Gender Medicine

    History and Highlights
    • 1st Edition
    • Marianne Legato J + 1 more
    • English
    The International Society for Gender Medicine: History and Highlights is about a major step in the improvement of quality in medicine, namely the long overdue understanding that women are different from men in every system of the body and may require different approaches in diagnosis and treatment. This is not a textbook, nor is it a scientific publication. It is the story of the International Society for Gender Medicine (IGM) as soon through the eyes of 12 pioneers of Gender and Sex Specific Medicine (GSSM) from seven countries, five of whom were the founds of IGM in 2006. It describes the development of this new science in the respective countries and academic environments of the authors, their very personal experience while promoting, and implementing their vision of GSSM, their frustrations, successes, and achievements. The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender and sex. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, cancer, osteoporosis, diabetes, obesity, and infectious diseases. This book is essential reading for all researchers, graduate students, practitioners, and anyone interested in this diverse and thriving field. From the early beginning, to the recent NIH mandate that females be included in pre-clinical as well as clinical research and that research results be reported by sex, the quick read will broaden your understanding of the history of the field and highlight where the future is headed.

  • Realizing the Promise of Precision Medicine

    The Role of Patient Data, Mobile Technology, and Consumer Engagement
    • 1st Edition
    • Paul Cerrato + 1 more
    • English
    Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases.

  • MiRNAs in Aging and Cancer

    • 1st Edition
    • Volume 334
    • English
    MiRNAs in Aging and Cancer, Volume 334, the latest in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. This new release includes chapters on a variety of timely topics, including the Regulation of autophagy by miRNAs, the Impact of miRNAs in cellular senescence, miRNAs in hematopoiesis, stem cell biology and hematological disorders, the Impact of miRNAs on longevity, miRNA deregulation in cardiovascular aging and associated disorders, miRNA deregulation in aging-associated pathologies of the skeletal muscle, and miRNAs and neurodegeneration. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • The Cardiovascular System

    Morphology, Control and Function
    • 1st Edition
    • Volume 36A
    • A. Kurt Gamperl + 3 more
    • English
    The Cardiovascular System: Design, Control and Function, Volume 36A, a two- volume set, not only provides comprehensive coverage of the current knowledge in this very active and growing field of research, but also highlights the diversity in cardiovascular morphology and function and the anatomical and physiological plasticity shown by fish taxa that are faced with various abiotic and biotic challenges. Updated topics in this important work include chapters on Heart Morphology and Anatomy, Cardiomyocyte Morphology and Physiology, Electrical Excitability of the Fish Heart, Cardiac Energy Metabolism, Heart Physiology and Function, Hormonal and Intrinsic Biochemical Control of Cardiac Function, and Vascular Anatomy and Morphology. In addition, chapters integrate molecular and cellular data with the growing body of knowledge on heart and in vivo cardiovascular function, and as a result, provide insights into some of the most important questions that still need to be answered.

  • Prion Protein

    • 1st Edition
    • Volume 150
    • English
    Prion Protein, Volume 150, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on Prion Protein, a protein that is considered to be the archetype of intrinsically disordered proteins. This updated volume includes comprehensive sections on a variety of timely topics, including Functions of Prion Protein, Copper and Prion protein, Cell Biology of Prion Protein, Structural Studies of Prion Proteins, Molecular Simulations on Wild Type and Mutant Prion Proteins, Genetics of Prion Protein, The Prion Concept and Synthetic Prions, and Transgenic Mouse Models. As neurodegenerative diseases represent a health issue that is receiving increasing attention from the scientific community due to their social and economic impact, this series is an ideal resource for the latest research in molecular biology and translational science.

  • Cannabinoid Pharmacology

    • 1st Edition
    • Volume 80
    • English
    Cannabinoid Pharmacology, Volume 80 is a new volume in the Advances in Pharmacology that presents reviews of recent breakthroughs. This volume aims to present current knowledge of the endogenous cannabinoid system, and looks at molecular, cellular, tissue and organismal effects of endogenous and exogenous cannabinoids. Topics of note in this new volume include Endocannabinoids and their congeners, Endocannabinoid turnover, Plant cannabinoids, Synthetic cannabinoids and ‘legal highs’, CB1 and CB2 cannabinoid receptors, Novel signaling modalities, Novel cannabinoid receptors, and Ion channel regulation by cannabinoids. There is a broad coverage of the essential elements associated with the cannabinoid system. The Editors have sought to include authors who represent authoritative voices on these themes, but have not previously worked together to allow a fresh approach to the individual aspects covered.

  • Advances in Genetics

    • 1st Edition
    • Volume 97
    • English
    Advances in Genetics, Volume 97 provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. New chapters in this recent release include Plant photomorphogenesis, TBC, and Exosome/EV Biomolecule Delivery "transfer". Users will find a series that continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • Advances in Immunology

    • 1st Edition
    • Volume 135
    • English
    Advances in Immunology, Volume 135, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this latest update including chapters on GPCR Biology, the Role of Caveolin-1 in BCR and TCR Receptors, New Developments in the Chemokine Field, and The Complement System in Developmental Neurobiology and Neurodegeneration. Readers will find comprehensive information on molecular and cellular activation mechanisms, phylogeny and molecular evolution and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • In Vivo Models to Study Angiogenesis

    • 1st Edition
    • Domenico Ribatti
    • English
    In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents the latest information from the extensive literature and research available. Evidence is now emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Thus, endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling.

  • Nature's Machines

    An Introduction to Organismal Biomechanics
    • 1st Edition
    • David E. Alexander
    • English
    Nature’s Machines: An Introduction to Organismal Biomechanics presents the fundamental principles of biomechanics in a concise, accessible way while maintaining necessary rigor. It covers the central principles of whole-organism biomechanics as they apply across the animal and plant kingdoms, featuring brief, tightly-focused coverage that does for biologists what H. M. Frost’s 1967 Introduction to Biomechanics did for physicians. Frequently encountered, basic concepts such as stress and strain, Young’s modulus, force coefficients, viscosity, and Reynolds number are introduced in early chapters in a self-contained format, making them quickly available for learning and as a refresher. More sophisticated, integrative concepts such as viscoelasticity or properties of hydrostats are covered in the later chapters, where they draw on information from multiple earlier sections of the book. Animal and plant biomechanics is now a common research area widely acknowledged by organismal biologists to have broad relevance. Most of the day-to-day activities of an animal involve mechanical processes, and to the extent that organisms are shaped by adaptive evolution, many of those adaptations are constrained and channelized by mechanical properties. The similarity in body shape of a porpoise and a tuna is no coincidence. Many may feel that they have an intuitive understanding of many of the mechanical processes that affect animals and plants, but careful biomechanical analyses often yield counterintuitive results: soft, squishy kelp may be better at withstanding pounding waves during storms than hard-shelled mollusks; really small swimmers might benefit from being spherical rather than streamlined; our bones can operate without breaking for decades, whereas steel surgical implants exhibit fatigue failures in a few months if not fully supported by bone.

  • Cutaneous Melanoma

    A Pocket Guide for Diagnosis and Management
    • 1st Edition
    • Giuseppe Argenziano + 5 more
    • English
    Cutaneous Melanoma: A Pocket Guide for Diagnosis and Management serves as an easy-to-consult, short, and schematic reference providing guidelines for diagnosing and managing melanoma in the context of various clinical scenarios. In the daily routine of a busy clinician, there is a need for schematic reference tools that allow quick consultation for immediate decisions. Melanoma is a deadly disease that should be promptly managed following precise and evidence-based guidelines. The guide contains many schematics and figures, vastly outnumbering the pages dedicated to text. This guide follows the sequence of a real clinical setting, going from the first screening visit to the final stages of terminal patients.

  • Advances in Sheep Welfare

    • 1st Edition
    • Drewe Ferguson + 2 more
    • English
    Advances in Sheep Welfare examines the recent advances made in sheep welfare assessment, handling and management, providing state-of-the-art coverage of the welfare needs of one of the world’s most widely farmed animals. The book begins with an introduction to sheep welfare in Part One, with chapters covering biology and natural behavior, sheep production systems, and consumer and societal expectations for sheep products. Part Two goes on to highlight new advances in sheep welfare assessment, before Part Three outlines a wide range of solutions to sheep welfare challenges. The final section looks ahead to the future, considering what sheep welfare will look like in 2030 and beyond. This book is an essential part of the wider ranging series Advances in Farm Animal Welfare, with coverage of cattle, sheep, pigs and poultry. With its expert editors and international team of contributors, Advances in Sheep Welfare is a key reference tool for welfare research scientists and students, veterinarians involved in welfare assessment, and indeed anyone with a professional interest in the welfare of sheep.

  • Vital Models

    The Making and Use of Models in the Brain Sciences
    • 1st Edition
    • Volume 233
    • English
    The use of models has been important to the historical and contemporary study of the human brain, yet very little study by social scientists has been dedicated to how the brain sciences develop and use models to better understand what brains are and how they work, including the complex entanglements between brains, bodies and their environments. Vital Models: The Making and Use of Models in the Brain Sciences explores the history and use of brain models from clinical psychiatry to psychopharmacology and cybernetics, as well as developments in digital brain modeling, simulation, imaging and connectomics. This timely volume helps both scientists and students better understand the variety, strengths, weaknesses and applicability of models in neuroscience.

  • RNA Methodologies

    Laboratory Guide for Isolation and Characterization
    • 5th Edition
    • Robert E. Farrell Jr.
    • English
    RNA Methodologies, Fifth Edition continues its tradition of excellence in providing the most up-to-date ribonucleic acid lab techniques for seasoned scientists and graduate students alike. This edition features new material on the exploding field of microRNA as well as the methods for the profiling of gene expression, both which have changed considerably in recent years. As a leader in the field, Dr. Farrell provides a wealth of knowledge on the topic of RNA while also giving readers helpful hints from his own personal experience in this subject area. Beginning with the most contemporary, RNA Methodologies, Fifth Edition, presents the essential techniques to use when working with RNA for the experienced practitioner while at the same time providing images and examples to aid the beginner in fully understanding this important branch of molecular biology. The next generation of scientists can look to this work as a guide for ensuring high productivity and highly representative data, as well as best practices in troubleshooting laboratory problems when they arise.

  • Neurobiology of Chinese Herb Medicine

    • 1st Edition
    • Volume 135
    • English
    Neurobiology of Chinese Herb Medicine, Volume 135 is a valuable book for anyone interested in alternative medicine or the scientific research surrounding ancient herbal medicine. This updated volume in the series includes chapters that delve into timely topics, including the Effects of Lycium Barbarum on the Visual System, the Effect of Chinese Herbal Medicine on Alzheimer’s Disease, the Effect and Mechanism of Chinese Herbal Medicine on Parkinson’s Disease, the Neurobiology of Chinese Herbal Medicine on Major Depressive Disorder, the Treatment of Insomnia with Traditional Chinese Herbal Medicine, and the Metabolic Factors and Adult Neurogenesis: Impacts of Chinese Herbal Medicine on Brain Repair in Neurological Diseases. This series is ideal for Chinese herbal medicine practitioners who are working in a clinical environment, although the clinical applications of Chinese medicinal herbs presented provide useful references and guidance for any clinical practice that specializes in the treatment of various conditions.

  • Future Directions in Biocatalysis

    • 2nd Edition
    • Tomoko Matsuda
    • English
    Future Directions in Biocatalysis, Second Edition, presents the future direction and latest research on how to utilize enzymes, i.e., natural catalysts, to make medicines and other necessities for humans. It emphasizes the most important and unique research on biocatalysis instead of simply detailing the ABC’s on the topic. This book is an indispensable tool for new researchers in the field to help identify specific needs, start new projects that address current environmental concerns, and develop techniques based on green technology. It provides invaluable hints and clues for conducting new research on enzymes, with final sections outlining future directions in biocatalysis further expanding the science into new applications.

  • Gnotobiotics

    • 1st Edition
    • Trenton R Schoeb + 1 more
    • English
    Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiom... related research, this volume collates the research of this expanding field into one definitive resource.

  • Soil Nematodes of Grasslands in Northern China

    • 1st Edition
    • Qi Li + 3 more
    • English
    Soil Nematodes of Grasslands in Northern China presents research on China’s temperate grasslands, providing the findings and results of a large field survey along a transect across the northern temperate grassland. It examines nematode distribution patterns along the transect from trophic group and family, to genus level, also evaluating their relationship with climatic conditions, plant biomass and soil parameters. The book then presents detailed taxonomy information of nematodes to genus or species level, providing keen insights into nematode diversity along the grassland transect in north China. Final sections review the advances and perspectives for the research of soil ecology on soil nematodes in China, including recent major discoveries of soil microbial diversity and eco-function during this field survey. This work will help researchers predict the impact of global change drivers on below ground soil biota and better understand the functioning and services they provide in terrestrial ecosystems.

  • Nonmotor Parkinson's: The Hidden Face

    Management and the Hidden Face of Related Disorders
    • 1st Edition
    • Volume 134
    • English
    Non-motor Parkinson's: The Hidden Face-Management and the Hidden Face of Related Disorders, Volume 134, the latest release in the International Review of Neurobiology series, is an up-to-date and comprehensive textbook addressing non-motor aspects of Parkinson’s disease, a key unmet need. Specific chapters in this updated release include Therapeutics and NMS in PD, Non-motor effects of conventional and transdermal therapies in PD, Infusion therapy, CDD and NMS in PD, DBS and NMS in PD, TMS and implications for NMS in PD, Botulinum toxin therapy and NMS in PD, and Nutrition and NMS in PD, amongst others. Including practical tips for non-specialists and clinical algorithms, the book contains contributions from over 40 opinion leaders in the field of movement disorders. It provides practitioners and researchers with a laboratory, to bedside, to caregiver perspective.

  • Viruses

    From Understanding to Investigation
    • 1st Edition
    • Susan Payne
    • English
    Viruses: From Understanding to Investigation provides students with a map for lifetime learning by presenting the definition and unique characteristics of viruses, including major topics, such as the virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study viruses. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work.

  • Ultrasound: Advances in Food Processing and Preservation

    • 1st Edition
    • Daniela Bermudez-Aguirre
    • English
    Ultrasound is an emerging technology that has been widely explored in foodscience and technology since the late 1990s. The book is divided into three main areas.Chapters 1 to 5 focus on the basic principles of ultrasound and how the technology works on microbial cells, enzymes, and the chemistry behind the process. Chapters 6 to 15 cover the application of ultrasound in specific food products and processes, discussing changes on food quality and presenting some innovations in food ingredients and enhancement of unit operations. Finally, Chapters 16 to 20 present some topics about manufacture of ultrasound equipment and simulation of the process, the use of the technology to treat food industry wastewater, and an industry perspective. The laws and regulations concerning emerging technologies, such as ultrasound, are also discussed, including the new Food Safety Modernization Act.

  • Connected Objects in Health

    Risks, Uses and Perspectives
    • 1st Edition
    • Laure Beyala
    • English
    Connected objects today present a range of opportunities in medicine. We live in a new digital era where the monitoring and analysis of one’s own health information no longer belongs solely to the realm of science fiction. The success of these new devices resides in their usage, which integrates seamlessly into the daily life of the user in order to continually collect the maximum amount of data. These medical connected devices therefore constitute a new hope in transforming user experience as well as the care pathway. They offer a better level of support and a better quality of life for those suffering from chronic illnesses or mental, sensorial or physical disabilities. However, these solutions also pose systematic problems, especially regarding the risks linked to their usage. This book presents a cartography which clearly details all the potential risk scenarios linked to the usage of connected devices as well as the actions which should be undertaken to promote balanced governance and guarantee the development of high-quality medical devices.

  • Nonmotor Parkinson's: The Hidden Face

    The Many Hidden Faces
    • 1st Edition
    • Volume 133
    • English
    Non-motor Parkinson's: The Hidden Face, Volume 133, the first part of the latest volume in the International Review of Neurobiology series, is an up-to-date, comprehensive textbook addressing the non-motor aspects of Parkinson’s disease, a key unmet need. Chapters in this new release include topics such as The hidden face of Parkinson's, JP and non-motor symptoms, Parkinson's: a complex non-motor disease, Neuropathology of NMS of PD, Neurophysiology and animal models related to NMS in PD, Epidemiology of NMS in PD (cohort studies), Genes and NMS in PD, NMS in genetic forms of PD, and Imaging the NMS in PD. Including practical tips for non-specialists and clinical algorithms, this book contains contributions from over 40 opinion leaders in the field of movement disorders, covering the topic from laboratory, to bedside, to caregiver.

  • Surgical Treatment of Atrial Fibrillation

    A Comprehensive Guide to Performing the Cox Maze IV Procedure
    • 1st Edition
    • Jonathan Philpott + 2 more
    • English
    Surgical Treatment of Atrial Fibrillation: A Comprehensive Guide to Performing the Cox-Maze IV Procedure is the first all-inclusive description of this rapidly growing surgery, setting the standard in the field. The Cox-Maze IV procedure is a complex surgery, and its success depends critically on correct execution. With FDA approval, the first RF ablation device for treatment of the Cox-Maze IV procedure has become more important than ever to combine scientific information for the procedure with its connection to human application. This comprehensive text provides step-by-step instructions from an experienced Cox-Maze IV surgeon and is written in the style of a mentor advising his mentee in the operating room. It contains over a dozen lessons described in detail, with illustrations, photographs and a discussion of possible complications and appropriate ways to deal with them. Additionally, the book describes sequencing for the surgeries that are typically performed concomitant with the Cox-Maze IV procedure, determining the optimal way to combine surgeries. Cardiac surgeons, fellows in cardiac surgery, medical students inclined toward cardiac surgery and cardiology researchers will find this book to be of great importance to their work.

  • A Structure-Function Toolbox for Membrane Transporter and Channels

    • 1st Edition
    • Volume 594
    • English
    A Structure-Function Toolbox for Membrane Transporter and Channels, Volume 594, a new release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters in the updated serial include Cryo-EM on membrane proteins embedded in nanodics, Solid-Supported membrane-based electrophysiology on membrane transporters and channels, Saposin-lipoprotein scaffolds for structure determination of membrane transporters and channels, Single-molecule FRET on transporters, Dynamics of channels and transporters investigated by NMR, Structure-function studies on channels and transporters, and a section on MemStar, a new GFP-based expression and purification system for transporters and channels.

  • Health Reform Policy to Practice

    Oregon’s Path to a Sustainable Health System: A Study in Innovation
    • 1st Edition
    • Ronald Stock + 1 more
    • English
    Health Reform Policy to Practice: Oregon as a Case Study for a Path to a Comprehensive and Sustainable Health Delivery Model offers a real world example of an innovative, successful and comprehensive program conducted by the U.S. State of Oregon. In 1991, Oregon embarked on a journey to improve health for all its citizens by radically re-thinking how to approach health care for long-term benefits. Over more than two decades, Oregonians have participated in a dialogue to create a new approach to solve the dilemma of providing high quality health care that is affordable and effective. Traditionally, health care reform looked at cutting people from care, cutting provider rates or cutting services. Oregon’s approach is unique in that it built a new system of delivery from the ground (community) up. The Oregon model took a “Fourth Path” to health care by redesigning the clinical delivery system through reducing waste, improving individual health and prevention, and therefore reducing utilization of services, creating local accountability, aligning financial incentives and creating fiscal accountability. This is not only an Oregon story, but a national one as other states, payers and purchasers implement health care reform.

  • Microbial Production of Food Ingredients and Additives

    • 1st Edition
    • Volume 5
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Microbial Production of Food Ingredients and Additives, Volume Five, the latest release in the Handbook of Food Bioengineering series, is a solid resource on how microorganisms can increase food production and quality. Microorganisms are used to create and enhance food, used as food additives to improve food taste, and in improving function and fortification to benefit overall health. The book presents the applications of microbial products in food bioengineering and methods to obtain valuable ingredients, such as sugars, acids, secondary metabolites, enzymes and vitamins. Recent and future applications of these microbial – derived food components are discussed, along with future applications.

  • Comprendre la paralysie cérébrale et les troubles associés

    Évaluations et traitements
    • 2nd Edition
    • Danièle Truscelli + 12 more
    • French
    Comprendre la paralysie cérébrale et les troubles associés est une refonte du livre précédent sur les infirmités motrices cérébrales. Son originalité réside dans le fait qu’il s’engage sur la voie du pronostic autant clinique qu’humain. L’approche médicale est large, de l’atteinte neuromotrice, orthopédique, des troubles de la santé aux facteurs de dysfonctionnement psychologique et/ou neuropsychologique. La recherche d’indices pronostiques dépend d’éléments cliniques déjà validés et s’appuie aussi sur des connaissances scientifiques récentes, comme la plasticité cérébrale.La parole donnée aux adultes en situation de handicap, voire aux familles, permet de suivre la pertinence de l’application des décisions thérapeutiques qu’ils ont vécues. Leurs témoignages indiquent leur dynamique pour trouver une qualité de vie personnalisée et leur volonté de trouver des contacts humains élargis. Des textes complémentaires, des références ainsi que des séquences vidéos montrant les divers aspects de la prise en charge en rééducation et en chirurgie orthopédique sont proposés en ligne. Coécrit par des équipes multidisciplinaires et référentes – médecins de médecine physique et de réadaptation (MPR), pédiatres, chirurgiens, rééducateurs, psychologues, scientifiques –, cet ouvrage a été coordonné par le docteur Danièle Truscelli.

  • Separation of Cells and Subcellular Elements

    Proceedings of a Meeting Organised by EFRAC (European Working Party for the Separation and Detection of Biological Fractions), Sponsored by the Committee for Science and Technology of the Council of Europe, Brussels, 4-5 May 1979
    • 1st Edition
    • H. Peeters
    • English
    Separation of Cells and Subcellular Elements presents the chemical engineering approaches in bio-separation methods. This book evaluates the cellular aggregation in turbulent suspension, the phase partition of cells and subcellular particles, and the continuous free-flow electrophoresis. The first chapters deal with flow cytometric characterization of tumor associated changes in gynecologic malignancies; steady state rheolectrolysis; and electrophoretic approaches applicable to cell separation. The succeeding chapters consider the chromosome separation by velocity sedimentation at unit gravity and the separation of human lymphocytes based on volume and density. Other chapters describe the analysis of the gradient former for zonal rotors and the centrifugal elutriation of living cells. The last chapters are devoted to the human platelet isolation from whole blood on metrizamide gradients. The book can provide useful information to biochemists, cytologists, students, and researchers.

  • Haematology Case Studies with Blood Cell Morphology and Pathophysiology

    • 1st Edition
    • Indu Singh + 3 more
    • English
    Hematology Case Studies with Blood Cell Morphology and Pathophysiology compiles specialized case studies with specific information on various hematological disorders with Full Blood Examination (FBE or CBC), blood film images and pathophysiology of each condition. In addition, it provides basic information on how to recognize and diagnose hematological conditions that are frequently observed in the laboratory. Technicians and scientists working in core laboratories such as biochemistry labs or blood banks will find this book to be extremely thorough. Moreover, it can be used as a reference book by technicians, scientists and hematologists in every level of expertise in diagnosing hematological disorders.

  • Myxomycetes

    Biology, Systematics, Biogeography and Ecology
    • 1st Edition
    • Carlos Rojas + 1 more
    • English
    Myxomycetes: Biology, Systematics, Biogeography, and Ecology is a comprehensive overview of the body of accumulated knowledge that now exists on myxomycetes. Its broad scope takes an integrated approach to the knowledge of this organismal group, considering a number of important aspects of their genetics and molecular phylogeny. It also treats myxomycetes as a distinct group from fungi, and includes molecular information that discusses the systematics and evolutionary pathways of the group. Additionally, biomedical and engineering applicability is discussed, thus expanding the audience and use of the book in a multidisciplinary context. The book provides an authoritative resource for students, researchers and educators interested in the fields of protistology, microbial ecology, molecular microbiology, biogeography, mycology, biodiversity, and evolutionary biology, and will also interest the amateur naturalist and biologist.

  • Evolution since Coding

    Cradles, Halos, Barrels, and Wings
    • 1st Edition
    • Zachary F. Burton
    • English
    Evolution since Coding: Cradles, Halos, Barrels, and Wings describes genesis of metabolism, transcription, translation, cell structure, eukaryotic complexity, LUCA (the last universal common (cellular) ancestor), the great divergence of archaea and bacteria, LECA (the last eukaryotic common ancestor), extinction, and cancer in very simple ways. The work (almost) "synthesizes life from scratch" (since coding) and describes the tools for readers to check the author’s work. As a result, readers understand living systems and their evolution in a conceptual way and are empowered to utilize powerful but accessible tools in computer-based biology. The work serves as foundational reading for a variety of researchers, academics, and students in life sciences, for example in evolution/evolutiona... biology, biochemistry, genetics/molecular genetics, molecular biology, cell biology, and microbiology, as well as disciplines beyond biological science. Its approachable style makes the book accessible for introductory students and educated laypersons. Evolution since Coding is suitable to supplement college courses that mix computers, evolution, and biology from freshman to senior level.

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