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Elsevier

Books in Life sciences

  • Managing Quality of Fruit and Vegetables

    • 1st Edition
    • Umezuruike Linus Opara
    • English
    Managing Quality of Fruit and Vegetables covers the application of proven and novel industrial approaches to quality management of fresh produce that have become common practice among local and global fresh produce chains while also covering the latest postharvest technologies for maintaining quality and safety. In addition, it addresses the impacts of emerging global challenges, such as climate change, the role of fruit and vegetables on nutrition security, and the development of future postharvest technologies to maintain quality and safety. Both academics and post-graduate students studying fresh produce supply chains and industry professionals will find this book extremely useful.Split into three broad themes, the book brings to light the latest developments on the biochemical and physiological basis for the quality of fruit and vegetables, the industrial approaches to quality management of fruit and vegetables, and the latest advances in postharvest technologies for controlling and maintaining quality.

  • Biological Emerging Risks in Foods

    • 1st Edition
    • Volume 86
    • English
    Biological Emerging Risks in Foods, Volume 86, addresses the emerging biological risks in food from a global context. Specific sections in this new release include discussions on parasites in foods as an emerging issue and antimicrobial resistance in the food chain. Specific chapters cover Norovirus: the burden of the unknown, Hepatitis E virus: a new foodborne zoonotic concern, Parasites in foods: from a neglected position to an emerging issue, Antimicrobial resistance in the food chain: an emerging global concern, Salmonella in foods: a reemerging problem, Listeria monocytogenes in foods, and Campylobacter in the food chain.

  • Fundamentals of Congenital Minimally Invasive Cardiac Surgery

    • 1st Edition
    • Vladimiro Vida + 1 more
    • English
    Fundamentals of Congenital Minimally Invasive Cardiac Surgery is a first of its kind, fully-illustrated guide that is solely dedicated to the most diffused congenital minimally invasive cardiac surgery procedures. It provides detailed, step-by-step descriptions of surgical maneuvers to underline each aspect of the procedures along with full color drawings and operative pictures to enhance understanding. Each chapter fully describes the preoperative setting, the needed materials and the required technical skills that make specific congenital heart defects amenable to minimally invasive surgical treatment. This is the perfect go-to reference for pediatric and congenital cardiac surgeons, and is also a must-have guide for residents in cardiac surgery who are looking to review the technical aspects and outcomes of utilizing a minimally invasive approach for cardiac surgery.

  • The Sourcebook for Clinical Research

    A Practical Guide for Study Conduct
    • 1st Edition
    • Jeff Nelligan + 1 more
    • English
    A single trial is complex, with numerous regulations, administrative processes, medical procedures, deadlines and specific protocol instructions to follow. And yet, there has existed no single-volume, comprehensive clinical research reference manual for investigators, medical institutions, and national and international research personnel to keep on the shelf as a ready reference to navigate through trial complexities and ensure compliance with U.S. Federal Regulations and ICH GCP until The Sourcebook for Clinical Research. An actionable, step-by-step guide through beginning to advanced topics in clinical research with forms, templates and checklists to download from a companion website, so that study teams will be compliant and will find all the necessary tools within this book. Additionally, the authors developed Display Posters for Adverse Events Plus Reporting and Medicare Coverage Analysis that can be purchased separately here: https://www.elsevier... Moreover, The Sourcebook for Clinical Research contains clear information and guidance on the newest changes in the industry to keep seasoned investigators and staff current and compliant, in addition to providing detailed information regarding the most complex topics. This book serves as a quick, actionable, off-the-shelf resource to keep by your side at the medical clinic.

  • Mitochondria and Longevity

    • 1st Edition
    • Volume 340
    • English
    Mitochondria and Longevity, Volume 340, the latest release in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics with this release focusing on topics such as Mitochondria metabolism and aging, Mitohormesis, Mitochondrial dynamics in the aging stem cell compartment, Mitochondrial proteostasis and aging, Mitochondrial DNA mutations and aging, Mitochondrial sirtuins, NAD+, NADH and aging, Mitophagy and aging, Mitochondria, calcium transport and aging.

  • Neuroinflammation

    • 2nd Edition
    • Alireza Minagar
    • English
    Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.

  • Neuroepigenetics and Mental Illness

    • 1st Edition
    • Volume 158
    • Bart P.F. Rutten
    • English
    Neuroepigenetics and Mental Illness, Volume 158, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series seeks to provide readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, with this release focusing on Neuroepigenetics in mental illness, Neuroepigenetics of development and neurodevelopmental disorder, Neuroepigenetics of aging and age-related neurodegenerative disorders, Neuroepigenetics of prenatal psychological stress, Neuroepigenetics of the HPA axis, Neuroepigenetics of the serotonergic system, and more.

  • Advances in Agronomy

    • 1st Edition
    • Volume 151
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 151, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Dosage Form Design Considerations

    Volume I
    • 1st Edition
    • English
    Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

  • Sphingolipids in Cancer

    • 1st Edition
    • Volume 140
    • English
    Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more.

  • Wearable Technology in Medicine and Health Care

    • 1st Edition
    • Raymond K. Y. Tong
    • English
    Wearable Technology in Medicine and Health Care provides readers with the most current research and information on the clinical and biomedical applications of wearable technology. Wearable devices provide applicability and convenience beyond many other means of technical interface and can include varying applications, such as personal entertainment, social communications and personalized health and fitness. The book covers the rapidly expanding development of wearable systems, thus enabling clinical and medical applications, such as disease management and rehabilitation. Final chapters discuss the challenges inherent to these rapidly evolving technologies.

  • Modern Techniques for Food Authentication

    • 2nd Edition
    • Da-Wen Sun
    • English
    Modern Techniques for Food Authentication, Second Edition presents a comprehensive review of the novel techniques available to authenticate food products, including various spectroscopic technologies, methods based on isotopic analysis and chromatography, and other techniques based on DNA, enzymatic analysis and electrophoresis. This new edition pinpoints research and development trends for those working in research, development and operations in the food industry, giving them readily accessible information on modern food authentication techniques to ensure a safe and authentic food supply. It will also serve as an essential reference source to undergraduate and postgraduate students, and for researchers in universities and research institutions.

  • Dosage Form Design Parameters

    Volume II
    • 1st Edition
    • English
    Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

  • Prostate Cancer

    A Case Report
    • 1st Edition
    • Gilles Plourde
    • English
    Prostate Cancer: A Case Report discusses the prevention, treatment modalities, and side effects of the medications used to treat prostate cancer. The book presents the most appropriate information, allowing patient empowerment to make informed decisions on their choice of treatments. Through the analysis of a real case report, the book also discusses the main complication associated with prostate cancer—bone metastasis—and provides information on treatment modalities for lung and liver metastasis. Diet, physical activities and the management of stress are also discussed, as is palliative care and the use of palliative sedation when other treatment modalities have failed. Cannabis, the pros and cons of euthanasia, and concerns raised by society are also covered. Esteemed author Dr. Plourde has more than 12 years’ experience working on drug safety, especially for biologic products involved in the treatment of various cancers. For more than 4 years he has suffered from prostate cancer with metastasis to the lungs and bones. During this time he has learned a lot on prostate cancer from the medical literature and from discussions with various specialists. The case report presented in this book represents his own medical history. Prostate Cancer: A Case Report provides the most relevant and up to date information on the various aspects involved in the screening, diagnosis and treatment of prostate cancer.

  • Manejo de la retinopatía diabética

    • 1st Edition
    • Caroline R. Baumal + 1 more
    • Spanish
    La obra analiza los factores de riesgo y la clasificación de la retinopatía diabética, además de estudiar cada modalidad de tratamiento. El título aborda los hot topic con las evidencias más recientes que guiarán al lector a través de cada opción terapéutica. Los casos clínicos que se presentan sirven para mostrar diversos aspectos del tratamiento de la retinopatía diabética complicada. Los autores han elaborado un práctico manual de ayuda para la selección de los fármacos más adecuados y que permitan obtener los mejores resultados para el paciente.

  • Darwin’s Pangenesis and Its Rediscovery Part A

    • 1st Edition
    • Volume 101
    • English
    Darwin’s Pangenesis and Its Rediscovery Part A highlights the findings of Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation that strengthened his theory of evolution and explained many phenomena of life. Now, new advances and the discovery of circulating cell-free DNA, mobile RNAs, prions and extracellular vesicles are providing new breakthroughs, thus increasing evidence on the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis suggests. Sections of note in this volume include the rationale, criticisms, influence and recent molecular evidence of Darwin's Pangenesis, as well as its relation to the inheritance of acquired characters, which is often included under the blanket term "transgenerational epigenetic inheritance."

  • Microfluidics in Cell Biology: Part A: Microfluidics for Multicellular Systems

    • 1st Edition
    • Volume 146
    • English
    Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids... Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chi... for pharmacokinetic analysis, Cancer immunotherapy on chips, and more.

  • Emergent Neuroimaging: A Patient Focused Approach, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 28-3
    • Diego B. Nunez
    • English
    This issue of Neuroimaging Clinics of North America focuses on Emergent Neuroimaging: A Patient Focused Approach, and is edited by Dr. Diego B. Nunez. Articles will include: The adult patient with acute neurologic deficit: an update on imaging trends; The patient with thunderclap headache; Imaging considerations in the patient with intracerebral hemorrhage; Emergent neuroimaging in the oncologic and immunosuppressed patient; Emergent neuroimaging during pregnancy and puerperium; Imaging the unconscious “found down” patient in the ED; Neurological emergencies in the pediatric patient including accidental and non-accidental trauma; Head and neck injuries: special considerations in the elderly patient; Current challenges in the use of CT and MRI in suspected cervical spine trauma; Radiation considerations in emergent neuroimaging; Blunt cranio-cervical trauma: Does the patient have a cerebral vascular injury?; New and emerging patient-centered CT imaging and image-guided treatment paradigms for maxillofacial trauma; Acute neurological syndromes beyond stroke: The role of emergent MRI; and more!

  • The Immune System and Mental Health

    • 1st Edition
    • Hymie Anisman + 2 more
    • English
    The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored.

  • Management of High Altitude Pathophysiology

    • 1st Edition
    • Kshipra Misra + 2 more
    • English
    Management of High Altitude Pathophysiology presents a comprehensive overview on the various therapeutic practices and ongoing research relating to the development of more potent and novel formulations for managing high altitude pathophysiology. It provides a detailed application of both herbal and non-herbal therapeutic agents, including their nanoformulations. This important reference provides benefits to the medical and herbal scientific communities, doctors treating patients with high altitude complications, individuals travelling to high altitudes for recreation or work, and scientists working on future drug development.

  • Dehydroepiandrosterone

    • 1st Edition
    • Volume 108
    • Gerald Litwack
    • English
    Dehydroepiandrostero... Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics such as Dehydroepiandrostero... Research: Past, Current and Future, Astrocyte Neuroprotection and Dehydroepiandrostero... Mutation of HSD3B2 Gene and Fate of Dehydroepiandrostero... Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrostero... Promotes Beneficial Effects on Human Health, Dehydroepiandrostero... and Cardiovascular Disease, Dehydroepiandrostero... and Experimental Osteoarthritis, The Role of Dehydroepiandrostero... (DHEA) in Skeletal Muscle, Mechanism of Action of Dehydroepiandrostero... and more.

  • Current Trends and Future Developments on (Bio-) Membranes

    Carbon Dioxide Separation/Capture by Using Membranes
    • 1st Edition
    • Angelo Basile + 1 more
    • English
    Current Trends and Future Developments on (Bio-) Membranes: Carbon Dioxide Separation/Capture by Using Membranes explores the unique property of membranes to separate gases with different physical and chemical properties. The book covers both polymeric and inorganic materials for CO2 separation and explains their mechanism of action, allowing for the development and most appropriate and efficient processes. It also lists the advantages of using membranes instead of other separation techniques, i.e., their low operating costs and low energy consumption. This book offers a unique opportunity for scientists working in the field of membrane technology for CO2 separation and capture.

  • The Value of BCG and TNF in Autoimmunity

    • 2nd Edition
    • Denise Faustman
    • English
    The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new prevention and treatment trials in autoimmunity and allergy, along with a new understanding of the genetics of BCGs.

  • Integrated Analytical Approaches for Pesticide Management

    • 1st Edition
    • Britt Maestroni + 1 more
    • English
    Integrated Analytical Approaches for Pesticide Management provides proven laboratory practices/examples and methods necessary to control pesticides in food and water in various environments. The book presents insights into good laboratory practices and examples of methods used in individual specialist laboratories, thus enabling stakeholders in the agri-food industry to appreciate the importance of proven, reliable data and the associated quality assurance approaches for end product testing for toxic levels of contaminant residues in food. The book is written in a rigorous, but simple, way to make sure that a broad range of readers can appreciate its technical content. The book's practical nature and generic guidelines distinguish it from others in the marketplace.

  • Transformative Paleobotany

    Papers to Commemorate the Life and Legacy of Thomas N. Taylor
    • 1st Edition
    • Michael Krings + 3 more
    • English
    Transformative Paleobotany: Papers to Commemorate the Life and Legacy of Thomas N. Taylor features the broadest possible spectrum of topics analyzing the structure, function and evolution of fossil plants, microorganisms, and organismal interactions in fossil ecosystems (e.g., plant paleobiography, paleoecology, early evolution of land plants, fossil fungi and microbial interactions with plants, systematics and phylogeny of major plant and fungal lineages, biostratigraphy, evolution of organismal interactions, ultrastructure, Antarctic paleobotany). The book includes the latest research from top scientists who have made transformative contributions. Sections are richly illustrated, well concepted, and characterize and summarize the most up-to-date understanding of this respective and important field of study.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 79
    • English
    Advances in Marine Biology, Volume 79, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. This latest release includes a review of patterns of multiple paternity across sea turtle rookeries, parasites and pathogens in seabirds, progress in marine genomics and bioinformatics, the rise of sea turtle research and conservation, and the potential impacts of offshore oil and gas activities on deep-sea sponges and the habitats they form.

  • Reproductomics

    The -Omics Revolution and Its Impact on Human Reproductive Medicine
    • 1st Edition
    • José A. Horcajadas + 1 more
    • English
    Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

  • Biscuit, Cookie and Cracker Production

    Process, Production and Packaging Equipment
    • 1st Edition
    • Iain Davidson
    • English
    Biscuit, Cookie, and Cracker Production: Process, Production, and Packaging Equipment is a practical reference that brings a complete description of the process and equipment necessary for automated food production in the food/biscuit industry. The book describes the existing and emerging technologies in biscuit making and production, bringing a valuable asset to R&D personnel and students in food technology and engineering areas. Full of clear illustrations, photos and text describing types of biscuits, cookies and crackers, ingredients, test bakery equipment, dough piece forming, biscuit baking ovens, biscuit cooling and handling, and processing and packaging, this book presents a timely resource on the topic.

  • Coronary Microvascular Obstruction in Acute Myocardial Infarction

    From Mechanisms to Treatment
    • 1st Edition
    • Giampaolo Niccoli + 1 more
    • English
    Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO.

  • Plasma Medical Science

    • 1st Edition
    • Shinya Toyokuni + 3 more
    • English
    Plasma Medical Science describes the progress that has been made in the field over the past five years, illustrating what readers must know to be successful. As non-thermal, atmospheric pressure plasma has been applied for a wide variety of medical fields, including wound healing, blood coagulation, and cancer therapy, this book is a timely resource on the topics discussed.

  • Pediatric Food Preferences and Eating Behaviors

    • 1st Edition
    • Julie C. Lumeng + 1 more
    • English
    Pediatric Food Preferences and Eating Behaviors reviews scientific works that investigate why children eat the way they do and whether eating behaviors are modifiable. The book begins with an introduction and historical perspective, and then delves into the development of flavor preferences, the role of repeated exposure and other types of learning, the effects of modeling eating behavior, picky eating, food neophobia, and food selectivity. Other sections discuss appetite regulation, the role of reward pathways, genetic contributions to eating behaviors, environmental influences, cognitive aspects, the development of loss of control eating, and food cognitions and nutrition knowledge. Written by leading researchers in the field, each chapter presents basic concepts and definitions, methodological issues pertaining to measurement, and the current state of scientific knowledge as well as directions for future research.

  • 3D Printing Applications in Cardiovascular Medicine

    • 1st Edition
    • James K Min + 3 more
    • English
    3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes.

  • Health Data Processing

    Systemic Approaches
    • 1st Edition
    • Marius Fieschi
    • English
    Health Data Processing: Systemic Approaches focuses on the design of health information systems and touches on the main themes of medical informatics and public health. The book is written for health professionals in practice or training, and is especially useful for decision-makers or future decision-makers in the field of health information systems. Users will find sections on the question of reusing data for other purposes, protection of individual liberties that this data and technologies make more acute, and the irruption of large masses of genetic data and its related problems. This book develops the methodological and conceptual aspects related to these issues.

  • Safety Risk Management for Medical Devices

    • 1st Edition
    • Bijan Elahi
    • English
    Safety Risk Management for Medical Devices demystifies risk management, providing clarity of thought and confidence to the practitioners of risk management as they do their work. Written with practicing engineers, safety management professionals, and students in mind, this book will help readers tackle the difficult questions, such as how to define risk acceptance criteria and how to determine when to stop risk reduction. This book delivers not only theory, but also practical guidance for applying the theory in daily risk management work. The reader is familiarized with the vocabulary of risk management and guided through a process to ensure compliance with the international standard ISO 14971—a requirement for all medical devices. This book outlines sensible, easily comprehensible, and state-of the-art methodologies that are rooted in current industry best practices. Opening chapters introduce the concept of risk, the legal basis for risk management, and the requirements for a compliant risk-management process. The next group of chapters discusses the connection between risk management and quality systems, usability engineering and biocompatibility. This book delves into the techniques of risk management, such as fault tree analysis and failure modes and effects analysis, and continues with risk estimation, risk control, and risk evaluation. Special topics such as software risk management, clinical investigations, and security are also discussed. The latter chapters address benefit-risk analysis, and production and postproduction monitoring. This book concludes with advice and wisdom for sensible, efficient, and successful safety risk management of medical devices.

  • Microalgae in Health and Disease Prevention

    • 1st Edition
    • Ira Levine + 1 more
    • English
    Microalgae in Health and Disease Prevention is a comprehensive reference that addresses the historical and potential use of microalgae, its extracts, secondary metabolites, and molecular constituents for enhancing human health and preventing diseases. Each chapter features an overview, and the book includes coverage of microalgae biology, harmful algae, the use of microalgae in alcohol and food, and as sources of macronutrients, micronutrients, vitamins, and minerals. The historical use of microalgae, in addition to its potential use as a nutraceutical and cosmeceutical, is also addressed. The book provides coverage of relevant, up-to-date research as assembled by a group of contributors who are dedicated to the advancement of microalgae use in health, diet and nutrition.

  • Encyclopedia of Reproduction

    • 2nd Edition
    • Michael K. Skinner
    • English
    Encyclopedia of Reproduction, Second Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field.

  • New Concepts in the Management of Septic Perianal Conditions

    • 1st Edition
    • Riyadh Mohammad Hasan + 1 more
    • English
    New Concepts in the Management of Septic Perianal Conditions provides a comprehensive review of the medically important basic and clinical aspects of perianal diseases in adults. This book presents current, medically important information in the rapidly changing field of anorectal diseases, including significant topics like perianal abscess and fistula. It provides an accurate source of clinically relevant information that is presented clearly and succinctly, making it perfect for the diagnosis, treatment and management of septic perianal conditions.

  • Mitosis and Meiosis Part B

    • 1st Edition
    • Volume 145
    • English
    Mitosis and Meiosis, Part B, Volume 145, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are chapters on Mitotic live cell imaging at different time scales, the characterization of mitotic spindle by multi-mode correlative microscopy, STED microscopy of mitosis, Correlating light microscopy with serial block face scanning electron microscopy to study mitotic spindle architecture, quantification of three-dimensional spindle architecture, Imaging based assays for mitotic chromosome condensation and dynamics, and more.

  • Cancer Nanotechnology

    • 1st Edition
    • Volume 139
    • English
    Advances in Cancer Research, Volume 139, provides invaluable information on the exciting and fast-moving field of cancer research. Original reviews are presented on a variety of topics relating to the rapidly developing intersection between nanotechnology and cancer research, with unique sections in the new release focusing on Exosomes as a theranostic for lung cancer, Nanotechnology and cancer immunotherapy, Ultrasound imaging agents and delivery systems, Dendronized systems for the delivery of chemotherapeutics, Thermosensitive liposomes for image-guided drug delivery, Supramolecular Chemistry in Tumor Analysis and Drug Delivery, Gold nanoparticles for delivery of cancer therapeutics, and Single cell barcode microchip for cancer research and therapy.

  • Atlas of Hematopathology

    Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
    • 2nd Edition
    • Faramarz Naeim + 3 more
    • English
    Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches, Second Edition, will appeal to both a wide range of people undergoing training in a variety of medical fields and practicing non-hematopathologis... For clinicians, fellows and residents, correct diagnosis (and therefore correct treatment) of diseases depends on a strong understanding of the molecular basis for the disease, making this book a crucial resource. This atlas contains hundreds of high-quality color images that mirror the findings that fellows and clinicians encounter in practice. In addition, it provides information in a quick, simple and user-friendly manner, attracting both those in training and non- experts. Residents, fellows, practicing clinicians, and researchers in pathology, hematology and hematology/oncology will find this a useful resource.

  • Epigenetics and Psychiatric Disease

    • 1st Edition
    • Volume 157
    • English
    Epigenetics and Psychiatric Disease, Volume 157, the latest volume in the Progress in Molecular Biology and Translational Science series, includes recent developments on a variety of topics, including the Epigenetic landscapes of the adversity-exposed brain, Chromosomal conformations and epigenomic regulation in schizophrenia, Progress in the epigenetics of depression, the epigenetics of circadian rhythms in imprinted neurodevelopmental disorders, DNA methylation mediating substance abuse, mechanisms and therapeutic opportunities, DNA methylation in animals model of psychosis, Epigenetics of early life stress, Epigenetic drugs for mood disorders, and more.

  • The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World

    • 1st Edition
    • Donald W. Duszynski + 2 more
    • English
    The fundamental concept of The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World is to provide an up-to-date reference guide to the identification, taxonomy, and known biology of apicomplexan intestinal and tissue parasites of carnivores including, but not limited to, geographic distribution, prevalence, sporulation, prepatent and patent periods, site(s) of infection in the definitive and (if known) intermediate hosts, endogenous development, cross-transmission, pathology, phylogeny, and (if known) their treatments. These data will allow easy parasite recognition with a summation of virtually everything now known about the biology of each parasite species covered. The last (very modest) and only treatise published on this subject was in 1981 so this book fills a fundamental gap in our knowledge of what is now known, and what is not, about the coccidian parasites that infect and sometimes kill carnivores and/or their prey that can harbor intermediate stages, including many domestic and game animals.

  • Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders

    • 1st Edition
    • Elizabeth B. Torres
    • English
    Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book introduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided.

  • Analytical Methods for Food Safety by Mass Spectrometry

    Volume I Pesticides
    • 1st Edition
    • Guo-Fang Pang
    • English
    Analytical Methods for Food Safety by Mass Spectrometry, Volume One: Pesticides systematically introduces the Pesticide and Veterinary Drug Multiresidues Analytical Methods. Volume One includes discussions on 20 pesticide multiresidues chromatic-MS (GC-MS and LC-MS/MS) analytical techniques that have the capability of detecting over 800 pesticides and chemicals in 10 categories of agricultural products, including fruits, vegetables, grains, teas, Chinese medicinal herbs, edible fungus mushrooms, fruit and vegetable juices, animal tissues, aquatic products, raw milk and milk powders, and drinkable water. This book also includes chromatic-MS analytical parameters, linear equations and GPC chromatic behavior parameters for over 800 pesticides. This valuable book can be used as reference for not only university students, but also technical personnel of different specialties who are engaged with study and applications, such as food safety, agricultural environment protection, pesticide development, and utilization in scientific research units, institutions and quality inspection organizations.

  • Marine enzymes and specialized metabolism - Part B

    • 1st Edition
    • Volume 605
    • English
    Marine enzymes and specialized metabolism - Part B, Volume 605 in the Methods in Enzymology series, highlights experimental methods on diverse marine enzymes involved in the construction of bioactive natural product molecules. Unique sections in this new release include discussions on polysaccharide-degra... enzymes from marine gastropods, radical SAM epimerases from sponge microbes, DMS/P demethylase in bacteria, reconstitution of particulate methane monooxygenase into membrane mimetics, the structure and function of cyanobactin enzymes, marine cyanobacterial polyketide beta-branching enzymology, marine cyanobacterial PKS-NRPS enzymology and structural biology, biochemical profiling of DMSP lyases, and more.

  • Transfusion Medicine for Pathologists

    A Comprehensive Review for Board Preparation, Certification, and Clinical Practice
    • 1st Edition
    • Brian Castillo + 4 more
    • English
    Transfusion Medicine for Pathologists: A Comprehensive Review for Board Preparation, Certification, and Clinical Practice is a concise study guide designed to complement standard textbooks in the field of clinical pathology. Pathology residents and fellows of transfusion medicine will find this book useful as a preparation tool for their exams. In addition, the book is a valuable timesaver for busy residents looking for a focused and compact study guide on transfusion medicine that will also be ideal for practicing pathologists who cross-cover transfusion medicine in their clinical practice.

  • Fibroblast Growth Factors

    • 1st Edition
    • Xiaokun Li
    • English
    Fibroblast Growth Factors presents research and results from the leading global research group on FGF, providing up-to-date and comprehensive coverage of the field. The book describes the history, basic research and growth engineering technology involved with FGFs, while also introducing detailed research methods. It comprises eight chapters that detail successes and problems in relation to wound healing of engineered growth factors and considers injury repair and regeneration, non-mitogenic mutants, structure modification, pathology, physiology, pharmacology, development, FGF/FGFR inhibitors, bioengineering, and new drug development. It will serve as a key reference book for researchers working on FGFs.

  • Studies on Hepatitis Viruses

    Life Cycle, Structure, Functions, and Inhibition
    • 1st Edition
    • Satya Prakash Gupta
    • English
    Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology and medicinal chemistry.

  • Food Fortification in a Globalized World

    • 1st Edition
    • M.G.Venkatesh Mannar + 1 more
    • English
    Food Fortification in a Globalized World outlines experiences over the past 50 years—and future potential—for the application of food fortification across a variety of foods in the industrialized and developing world. The book captures recent science and applications trends in fortification, including emerging areas such as biofortification, nutraceuticals and new nutrient intake recommendations, standards, policy and regulation. The book proposes a balanced and effective food fortification strategy for nations to adopt. In covering the most technical scientific details in an approachable style, this work is accessible to a range of practitioners in industry, government, NGOs, academia and research. Food fortification has become an increasingly significant strategy to address gaps in micronutrient intakes in populations with measurable impact in both industrialized and developing countries. While the positive impacts are well recognized there are new concerns in some countries that excessive fortification of foods, outdated nutritional labeling rules and misleading marketing tactics used by food manufacturers may result in young children consuming harmful amounts of some vitamins and minerals.

  • Genomic Medicine in Emerging Economies

    Genomics for Every Nation
    • 1st Edition
    • George P. Patrinos + 1 more
    • English
    Originally thought to be available only to the world’s wealthiest nations, genomic medicine has developed into a broad range of clinical methods and technologies whose concrete applications are also revolutionizing health systems in many of the world’s resource-limited nations. Genomic Medicine in Emerging Economies: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has already transformed health systems and led to improved patient care in Indonesian, Chilean, Malaysian, Argentinian, Chinese, Sri Lankan, and Colombian populations among others. In addition to defining tools, diagnostics, and treatment pathways at the population-wide level for medical geneticists, genomic researchers, and public health workers to apply in their own work, this book offers an essential, case-study based approach needed to understand how genomic medicine can be used to improve disease-management in a diverse range of economic and social contexts.

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