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Books in Life sciences

  • Brain-Computer Interfacing for Assistive Robotics

    Electroencephalograms, Recurrent Quantum Neural Networks, and User-Centric Graphical Interfaces
    • 1st Edition
    • Vaibhav Gandhi
    • English
    Brain-computer interface (BCI) technology provides a means of communication that allows individuals with severely impaired movement to communicate with assistive devices using the electroencephalogram (EEG) or other brain signals. The practicality of a BCI has been possible due to advances in multi-disciplinary areas of research related to cognitive neuroscience, brain-imaging techniques and human-computer interfaces. However, two major challenges remain in making BCI for assistive robotics practical for day-to-day use: the inherent lower bandwidth of BCI, and how to best handle the unknown embedded noise within the raw EEG. Brain-Computer Interfacing for Assistive Robotics is a result of research focusing on these important aspects of BCI for real-time assistive robotic application. It details the fundamental issues related to non-stationary EEG signal processing (filtering) and the need of an alternative approach for the same. Additionally, the book also discusses techniques for overcoming lower bandwidth of BCIs by designing novel use-centric graphical user interfaces. A detailed investigation into both these approaches is discussed.
  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 5 - Role in Human Diseases
    • 1st Edition
    • M. A. Hayat
    • English
    Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections. Volume 5 comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders. In spite of the increasing importance of autophagy in the various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases remains poorly understood. This book is an asset to newcomers as a concise overview of the diverse disease implications of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy’s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer’s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis.Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders.Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation.Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.
  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 312
    • Kwang W. Jeon
    • English
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.
  • Practical Predictive Analytics and Decisioning Systems for Medicine

    Informatics Accuracy and Cost-Effectiveness for Healthcare Administration and Delivery Including Medical Research
    • 1st Edition
    • Gary D. Miner + 7 more
    • English
    With the advent of electronic medical records years ago and the increasing capabilities of computers, our healthcare systems are sitting on growing mountains of data. Not only does the data grow from patient volume but the type of data we store is also growing exponentially. Practical Predictive Analytics and Decisioning Systems for Medicine provides research tools to analyze these large amounts of data and addresses some of the most pressing issues and challenges where data integrity is compromised: patient safety, patient communication, and patient information. Through the use of predictive analytic models and applications, this book is an invaluable resource to predict more accurate outcomes to help improve quality care in the healthcare and medical industries in the most cost–efficient manner.Practical Predictive Analytics and Decisioning Systems for Medicine provides the basics of predictive analytics for those new to the area and focuses on general philosophy and activities in the healthcare and medical system. It explains why predictive models are important, and how they can be applied to the predictive analysis process in order to solve real industry problems. Researchers need this valuable resource to improve data analysis skills and make more accurate and cost-effective decisions.
  • Advances in Fermented Foods and Beverages

    Improving Quality, Technologies and Health Benefits
    • 1st Edition
    • Wilhelm Holzapfel
    • English
    Fermentation is used in a wide range of food and beverage applications, and the technology for enhancing this process is continually evolving. This book reviews the use of fermentation in foods and beverages and key aspects of fermented food production. Part one covers the health benefits of fermented foods. Part two includes chapters on fermentation microbiology, while part three looks at ways of controlling and monitoring the quality and safety of fermented foods. Part four covers advances in fermentation technology. Finally, part five covers particular fermented food products.
  • Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders

    • 1st Edition
    • Volume 71
    • English
    This new volume of Advances in Pharmacology presents pharmacology of the blood brain barrier, focusing on targeting CNS disorders. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
  • Z Score Neurofeedback

    Clinical Applications
    • 1st Edition
    • Robert W. Thatcher + 1 more
    • English
    Neurofeedback is utilized by over 10,000 clinicians worldwide with new techniques and uses being found regularly. Z Score Neurofeedback is a new technique using a normative database to identify and target a specific individual’s area of dysregulation allowing for faster and more effective treatment. The book describes how to perform z Score Neurofeedback, as well as research indicating its effectiveness for a variety of disorders including pain, depression, anxiety, substance abuse, PTSD, ADHD, TBI, headache, frontal lobe disorders, or for cognitive enhancement. Suitable for clinicians as well as researchers this book is a one stop shop for those looking to understand and use this new technique.
  • The Endocannabinoidome

    The World of Endocannabinoids and Related Mediators
    • 1st Edition
    • Vincenzo Di Marzo + 1 more
    • English
    The Endocannabinoidome: The World of Endocannabinoids and Related Mediators is dedicated to the latest research and studies on endocannabinoids and cannabinoid receptors to illustrate their important role in the discovery of new, endocannabinoid-rela... lipid mediators. Written by leading experts across different disciplines, this book focuses on the biochemical and anlayticial aspects of novel lipid signals, their pharmacological activities and their potential utilization for the development of new and effective therapeutic strategies. The first book of its kind, The Endocannabinoidome is a meaningful reference for all those involved in experimental efforts to further the development of this field.
  • History of Toxicology and Environmental Health

    Toxicology in Antiquity II
    • 1st Edition
    • Philip Wexler
    • English
    This volume, Toxicology in Antiquity II, continues to tell the story of the roots of toxicology in ancient times. Readers learn that before scientific research methods were developed, toxicology thrived as a very practical discipline. Toxicologists are particularly proud of the rich and storied history of their field and there are few resources available that cover the discipline from a historical perspective. People living in ancient civilizations readily learned to distinguish safe from hazardous substances, how to avoid these hazardous substances and how to use them to inflict harm on enemies. Volume II explores the use of poison as weapons in war and assassinations, early instances of air pollution, the use of hallucinogens and entheogens, and the role of the snake in ancient toxicology.
  • Drugs During Pregnancy and Lactation

    Treatment Options and Risk Assessment
    • 3rd Edition
    • Christof Schaefer + 2 more
    • English
    Drugs During Pregnancy and Lactation, Third Edition is a quick and reliable reference for all those working in disciplines related to fertility, pregnancy, lactation, child health and human genetics who prescribe or deliver medicinal products, and to those who evaluate health and safety risks. Each chapter contains twofold information regarding drugs that are appropriate for prescription during pregnancy and an assessment of the risk of a drug when exposure during pregnancy has already occurred. Thoroughly updated with current regulations, references to the latest pharmacological data, and new medicinal products, this edition is a comprehensive resource covering latest knowledge and findings related to drugs during lactation and pregnancy.
  • Crop Physiology

    Applications for Genetic Improvement and Agronomy
    • 2nd Edition
    • Victor O. Sadras + 1 more
    • English
    From climate change to farming systems to genetic modification of organisms, Crop Physiology, Second Edition provides a practical tool for understanding the relationships and challenges of successful cropping. With a focus on genetic improvement and agronomy, this book addresses the challenges of environmentally sound production of bulk and quality food, fodder, fiber, and energy which are of ongoing international concern. The second edition of Crop Physiology continues to provide a unique analysis of these topics while reflecting important changes and advances in the relevant science and implementation systems. Contemporary agriculture confronts the challenge of increasing demand in terms of quantitative and qualitative production targets. These targets have to be achieved against the background of soil and water scarcity, worldwide and regional shifts in the patterns of land use driven by both climate change and the need to develop crop-based sources of energy, and the environmental and social aspects of agricultural sustainability.
  • Modulation of Sleep by Obesity, Diabetes, Age, and Diet

    • 1st Edition
    • Ronald Ross Watson
    • English
    Sleep disorder is a rampant problem in the US, with over 40 million Americans currently diagnosed according to the NIH. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes. This volume focuses on the interaction between sleep and these factors, with special attention being paid to the potential for neurological modulation of sleep via diet. The volume aid readers in understanding the role each of these factors plays in sleep architecture and its regulation by circadian biology and neurology.
  • Molecular Medical Microbiology

    • 2nd Edition
    • Yi-Wei Tang + 4 more
    • English
    The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource.This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging.Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more.
  • Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease

    Prevention and Therapy
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Nutritional supplement research concerning brain health and neurological disease is becoming an important focus. While nutritional supplements are very popular for general health and well being, the effectiveness of common supplements and their impact on general brain health and for the treatment or prevention of neurological disease is not clearly understood. This comprehensive introduction to bioactive nutraceuticals for brain and neurological provides a foundation review for research neuroscientists, clinical neurologists, pharmacology researchers and nutrition scientists on what we know now about these supplements and the brain and where focused research is still necessary.
  • Handbook of Food Allergen Detection and Control

    • 1st Edition
    • Simon Flanagan
    • English
    Allergens in food and their detection, management and elimination constitute a key issue for food manufacturers, especially in terms of safety. This book reviews current and emerging technologies for detecting and reducing allergens, as well as issues such as traceability, regulation and consumer attitudes. Following an introductory chapter by a distinguished expert, part one covers allergen management throughout the food chain. Part two details current and emerging methods of allergen detection in food, and part three covers methods for reducing and eliminating allergens in food. Finally, part four focuses on the control and detection of individual food allergens and the risks each one presents in food manufacture.
  • Thorp and Covich's Freshwater Invertebrates

    Ecology and General Biology
    • 4th Edition
    • James H. Thorp + 1 more
    • English
    Readers familiar with the first three editions of Ecology and Classification of North American Freshwater Invertebrates (edited by J.H. Thorp and A.P. Covich) will welcome the comprehensive revision and expansion of that trusted professional reference manual and educational textbook from a single North American tome into a developing multi-volume series covering inland water invertebrates of the world. The series entitled Thorp and Covich’s Freshwater Invertebrates (edited by J.H. Thorp) begins with the current Volume I: Ecology and General Biology (edited by J.H. Thorp and D.C. Rogers), which is designed as a companion volume for the remaining books in the series. Those following volumes provide taxonomic coverage for specific zoogeographic regions of the world, starting with Keys to Nearctic Fauna (Vol. II) and Keys to Palaearctic Fauna (Vol. III). Volume I maintains the ecological and general biological focus of the previous editions but now expands coverage globally in all chapters, includes more taxonomic groups (e.g., chapters on individual insect orders), and covers additional functional topics such as invasive species, economic impacts, and functional ecology. As in previous editions, the 4th edition of Ecology and Classification of North American Freshwater Invertebrates is designed for use by professionals in universities, government agencies, and private companies as well as by undergraduate and graduate students.
  • The Parathyroids

    Basic and Clinical Concepts
    • 3rd Edition
    • John P. Bilezikian + 5 more
    • English
    The third edition of The Parathyroids, led by a new stellar editorial team, has been thoroughly updated to reflect the considerable advances in just about every aspect of PTH biology over the past decade. It continues to be the authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium. This translational resource is invaluable to graduate students, fellows, researchers, and research clinicians in the fields of endocrinology, bone biology, osteology, and rheumatology.
  • Biophysical Characterization of Proteins in Developing Biopharmaceuticals

    • 1st Edition
    • Damian J. Houde + 1 more
    • English
    Biophysical Characterization of Proteins in Developing Biopharmaceuticals is concerned with the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure this book takes the reader on a journey on how to best achieve this goal using the key relevant and practical methods commonly employed in the biopharmaceutical industry today as well as up and coming promising methods that are now gaining increasing attention. As a general resource guide this book has been written with the intent to help today’s industrial scientists working in the biopharmaceutical industry or the scientists of tomorrow who are planning a career in this industry on how to successfully implement these biophysical methodologies. In so doing a keen focus is placed on understanding the capability of these methodologies in terms of what information they can deliver. Aspects of how to best acquire this biophysical information on these very complex drug molecules, while avoiding potential pitfalls, in order to make concise, well informed productive decisions about their development are key points that are also covered.
  • Signaling Pathways in Plants

    • 1st Edition
    • Volume 35
    • English
    This special issue of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This volume discusses signaling pathways in plants.
  • bHLH Transcription Factors in Development and Disease

    • 1st Edition
    • Volume 110
    • English
    This new volume of Current Topics in Developmental Biology provides a comprehensive set of reviews on bHLH transcription factors. bHLH factors are vastly recognized for their diverse roles in developmental processes and their dysfunction underlies various human pathologies. Each chapter is authoritatively written by a leading expert in the field and discusses every possible aspect of this huge and diverse field.
  • Heat Treatment for Insect Control

    Developments and Applications
    • 1st Edition
    • Dave Hammond
    • English
    Stored product insects and other pests represent a major hygiene and safety issue to many industries, from food production to building infestation, and issues for timber pallets and packaging. Beds bugs are rapidly becoming a public health issue in hotels, hostels and houses in many parts of the world. While fumigation has been one of the prevalent routes for pest control, there remain issues with the toxicity of the chemicals used and potential exposure to humans therefore heat treatment has proven to be a successful alternative when used correctly. It is well known that excessive heat is dangerous to life. There is a difference between the amount of heat required to kill microbes such as bacteria and viruses and that required to kill larger life forms such as insects or mammals. This book focuses on the use of heat to kill insects and mites in food production, storage and other facilities. Heat Treatment for Insect Control examines how controlled heat treatment kills all stages of pest insect life across species and without causing damage to surrounding structures or electronics. The advantages of heat treatment include no health & safety hazards, a completely controllable and environmentally friendly process, reduced treatment time of fumigation (hours verses days), as well as no factory shutdown or exclusion of staff from adjacent areas during treatment. Part I reviews the principles of heat treatment, with chapters covering the fundamentals, planning, best practice and costs of integrated pest management. Part II looks at heat treatment applications in food production, storage, food materials and fresh produce. Part III examines the other applications in clothing, small rooms, buildings, and transportation.
  • High Throughput Screening for Food Safety Assessment

    Biosensor Technologies, Hyperspectral Imaging and Practical Applications
    • 1st Edition
    • Arun K. Bhunia + 2 more
    • English
    Recent advances in array-based detectors and imaging technologies have provided high throughput systems that can operate within a substantially reduced timeframe and other techniques that can detect multiple contaminants at one time. These technologies are revolutionary in terms of food safety assessment in manufacturing, and will also have a significant impact on areas such as public health and food defence. This book summarizes the latest research and applications of sensor technologies for online and high throughput screening of food. The book first introduces high throughput screening strategies and technology platforms, and discusses key issues in sample collection and preparation. The subsequent chapters are then grouped into four sections: Part I reviews biorecognition techniques; Part II covers the use of optical biosensors and hyperspectral imaging in food safety assessment; Part III focuses on electrochemical and mass-based transducers; and finally Part IV deals with the application of these safety assessment technologies in specific food products, including meat and poultry, seafood, fruits and vegetables.
  • HIV and Endocrine Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 43-3
    • Paul Hruz
    • English
    This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Paul Hruz, is devoted to HIV and Endocrine Disorders. Articles in this issue include: Dyslipidemia and cardiovascular risk in HIV infection; Changes in nutritional concerns in HIV/AIDS; HIV Lipodystrophy: Lessons learned about adipose tissue and metabolic disorders; Hypogonadism in the HIV infected male; Gonadal function and reproductive health in women with HIV; Osteopenia, osteoporosis, and fracture risk with HIV infection and treatment; HIV-associated calcium and vitamin D abnormalities; Alterations in pancreatic islet function in HIV; Insulin resistance, glucose intolerance, and diabetes in HIV; Thyroid abnormalities in HIV; HPA axis/adrenal pathology in HIV; and Endocrinopathies in HIV-infected children.
  • Breathing, Emotion and Evolution

    • 1st Edition
    • Volume 212
    • English
    Respiration is one of the most basic motor activities crucial for survival of the individual. It is under total control of the central nervous system, which adjusts respiratory depth and frequency depending on the circumstances the individual finds itself. For this reason this volume not only reviews the basic control systems of respiration, located in the caudal brainstem, but also the higher brain regions, that change depth and frequency of respiration. Scientific knowledge of these systems is crucial for understanding the problems in the many patients suffering from respiratory failure.
  • Principles of Developmental Genetics

    • 2nd Edition
    • Sally A. Moody
    • English
    Providing expert coverage of all major events in early embryogenesis and the organogenesis of specific systems, and supplemented with representative clinical syndromes, Principles of Developmental Genetics, Second Edition discusses the processes of normal development in embryonic and prenatal animals, including humans. The new edition of this classic work supports clinical researchers developing future therapies with its all-new coverage of systems biology, stem cell biology, new technologies, and clinical disorders. A crystal-clear layout, exceptional full-color design, and bulleted summaries of major takeaways and clinical pathways assist comprehension and readability of the highly complex content.
  • Genetics of Epilepsy

    • 1st Edition
    • Volume 213
    • English
    The book chapters cover different aspects of epilepsy genetics, starting with the "classical" concept of epilepsies as ion channel disorders. The second part of the book gives credit to the fact that by now non-ion channel genes are recognized as equally important causes of epilepsy. The concluding chapters are designed to offer the reader insight into current methods in epilepsy research. Each chapter is self-contained and deals with a selected topic of interest.
  • Handbook of Cosmeceutical Excipients and their Safeties

    • 1st Edition
    • K Y Heng + 5 more
    • English
    Cosmeceuticals are the latest additions to the health industry and have an ever-expanding market. They are considered to be a marriage between cosmetics and drugs and are defined as preparations applied on the body that may modify the physiological functions of the skin. However, as more cosmeceuticals are being launched in the market and more types of drugs are incorporated into the formulation, the composition of cosmeceuticals is becoming more complex. Handbook of Cosmeceutical Excipients and their Safeties summarises the current evidence relating to cosmeceuticals’ side effects and highlights the important information that practitioners and consumers need to know, as well as ways to avoid the adverse effects of the excipients. Handbook of Cosmeceutical Excipients and their Safeties includes chapters covering topics such as the history of cosmeceuticals and the laws that regulate them, skin permeation, carcinogenicity as a systemic adverse effect and dermatitis as a topical adverse effect. It concludes with an appendix that gives brief information on the potency and permeability of common ingredients in cosmeceuticals. The appendix aims to highlight the maximum allowable quantity of each ingredient to ensure product safety for consumers. The appendix was prepared by compiling the ingredients of 257 products containing more than 500 compounds, collected from a hospital pharmacy in Singapore.
  • Soil Remediation and Plants

    Prospects and Challenges
    • 1st Edition
    • Khalid Hakeem + 3 more
    • English
    The soil is being contaminated continuously by a large number of pollutants. Among them, heavy metals are an exclusive group of toxicants because they are stable and difficult to disseminate into non-toxic forms. The ever-increasing concentrations of such pollutants in the soil are considered serious threats toward everyone’s health and the environment. Many techniques are used to clean, eliminate, obliterate or sequester these hazardous pollutants from the soil. However, these techniques can be costly, labor intensive, and often disquieting. Phytoremediation is a simple, cost effective, environmental friendly and fast-emerging new technology for eliminating toxic heavy metals and other related soil pollutants. Soil Remediation and Plants provides a common platform for biologists, agricultural engineers, environmental scientists, and chemists, working with a common aim of finding sustainable solutions to various environmental issues. The book provides an overview of ecosystem approaches and phytotechnologies and their cumulative significance in relation to solving various environmental problems.
  • Advances in Immunology

    • 1st Edition
    • Volume 124
    • Frederick W. Alt
    • English
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
  • Neuroimmune Signaling in Drug Actions and Addictions

    • 1st Edition
    • Volume 118
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Neuroimmune Signaling in Drug Actions and Addictions.
  • Adenosine Receptors in Neurology and Psychiatry

    • 1st Edition
    • Volume 119
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/developmen... in neurology and psychiatry areas.
  • Chesley's Hypertensive Disorders in Pregnancy

    • 4th Edition
    • Robert N. Taylor + 3 more
    • English
    Chesley’s Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial.The fourth edition of Chesley’s Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia.
  • The Biology of Thought

    A Neuronal Mechanism in the Generation of Thought - A New Molecular Model
    • 1st Edition
    • Krishnagopal Dharani
    • English
    The question of "what is thought" has intrigued society for ages, yet it is still a puzzle how the human brain can produce a myriad of thoughts and can store seemingly endless memories. All we know is that sensations received from the outside world imprint some sort of molecular signatures in neurons – or perhaps synapses – for future retrieval. What are these molecular signatures, and how are they made? How are thoughts generated and stored in neurons? The Biology of Thought explores these issues and proposes a new molecular model that sheds light on the basis of human thought. Step-by-step it describes a new hypothesis for how thought is produced at the micro-level in the brain – right at the neuron. Despite its many advances, the neurobiology field lacks a comprehensive explanation of the fundamental aspects of thought generation at the neuron level, and its relation to intelligence and memory. Derived from existing research in the field, this book attempts to lay biological foundations for this phenomenon through a novel mechanism termed the "Molecular-Grid Model" that may explain how biological electrochemical events occurring at the neuron interact to generate thoughts. The proposed molecular model is a testable hypothesis that hopes to change the way we understand critical brain function, and provides a starting point for major advances in this field that will be of interest to neuroscientists the world over.
  • Clinical Neuroendocrinology

    • 1st Edition
    • Volume 124
    • Eric Fliers + 2 more
    • English
    Clinical Neuroendocrinology, a volume in the Handbook of Clinical Neurology Series gives an overview of the current knowledge in the field of clinical neuroendocrinology. It focuses on the pathophysiology, diagnosis, and treatment of diseases of the hypothalamus and the pituitary gland. It integrates a large number of medical disciplines, including clinical endocrinology, pediatrics, neurosurgery, neuroradiology, clinical genetics, and radiotherapy. Psychological consequences of various disorders and therapies, as well as therapeutic controversies, are discussed. It is the first textbook in the field to address all these aspects by a range of international experts.
  • Dentine Hypersensitivity

    Developing a Person-centred Approach to Oral Health
    • 1st Edition
    • Peter Glenn Robinson
    • English
    Dentine Hypersensitivity: Developing a Person-Centred Approach to Oral Health provides a detailed and integrated account of interdisciplinary research into dentine hypersensitivity. The monograph will be of interest to all those working on person centred oral health related research because it provides not only an account of the findings of a series of studies into dentine hypersensitivity drawing on the research traditions of epidemiology, sociology psychology, and dental public health but an integrated study of the benefits of exploring a single oral condition from this range of disciplines.
  • Bone Cancer

    Primary Bone Cancers and Bone Metastases
    • 2nd Edition
    • Dominique Heymann
    • English
    Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases – from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.
  • Brain Transcriptome

    • 1st Edition
    • Volume 116
    • English
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome.
  • Primary Immunodeficiency Disorders

    A Historic and Scientific Perspective
    • 1st Edition
    • Amos Etzioni + 1 more
    • English
    Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way.
  • Cerebellar Conditioning and Learning

    • 1st Edition
    • Volume 117
    • English
    This volume of International Review of Neurobiology is on Cerebellar Conditioning and Learning. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field.
  • Méthodes en immunologie

    Des principes aux bonnes applications
    • 1st Edition
    • Collège des Enseignants d'Immunologie
    • French
    Cet ouvrage, rédigé sous l'égide de l'Assim, offre un tour d'horizon complet et synthétique de toutes les méthodes actuelles en immunologie. Il en recense les différentes pratiques, partant des principes de la méthode à leur application. Il s'articule en deux grandes parties : la première portant sur les techniques elles-mêmes ; la seconde dédiée à des domaines d'applications spécifiques et mobilisant parfois une grande diversité de techniques. Chacun des 14 chapitres est étayé d'illustrations et de tableaux synthétiques, et construit de telle sorte que le lecteur y retrouve: - une présentation générale de chaque technique ; - une description synoptique de la méthodologie ; - des recommandations spécifiques de mise en oeuvre ; - des indications sur le mode de présentation des résultats ; - des informations sur la validation des résultats ; - un point sur les avantages et les inconvénients propres à chaque technique ; - des exemples d'application pratiques.
  • Epigenetic Shaping of Sociosexual Interactions: From Plants to Humans

    • 1st Edition
    • Volume 86
    • English
    Epigenetic Shaping of Sociosexual Interactions: From Plants to Humans is the first attempt to interpret the higher social functions of organisms. This volume covers an extraordinarily wide range of biological research and provides a novel framework for understanding human-specific brain functions.
  • The Mitochondrion in Aging and Disease

    • 1st Edition
    • Volume 127
    • English
    Mitochondria, the "power plants" of eukaryotic cells, are best known for the generation of adenosine triphosphate (ATP), the universal cellular "energy currency" of the cell, and the synthesis of different essential components. Mitochondrial dysfunction is known to lead to various degenerative disorders, disease, and aging. The Mitochondrion in Aging and Disease works to unravel the processes leading to mitochondrial impairments and of pathways involved in mitochondrial quality control and their impact on health and aging will be addressed.
  • Insect Midgut and Insecticidal Proteins

    • 1st Edition
    • Volume 47
    • English
    This volume of Advances in Insect Physiology contains comprehensive interdisciplinary reviews on basic and practical aspects relevant to Insect Midgut and Insecticidal Proteins.
  • Imported Infectious Diseases

    The Impact in Developed Countries
    • 1st Edition
    • Fernando Cobo
    • English
    The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.
  • Translational Biology in Medicine

    • 1st Edition
    • M. Montano
    • English
    The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine.
  • Wearable Sensors

    Fundamentals, Implementation and Applications
    • 1st Edition
    • Edward Sazonov
    • English
    Written by industry experts, this book aims to provide you with an understanding of how to design and work with wearable sensors. Together these insights provide the first single source of information on wearable sensors that would be a valuable addition to the library of any engineer interested in this field.Wearable Sensors covers a wide variety of topics associated with the development and application of various wearable sensors. It also provides an overview and coherent summary of many aspects of current wearable sensor technology.Both industry professionals and academic researchers will benefit from this comprehensive reference which contains the most up-to-date information on the advancement of lightweight hardware, energy harvesting, signal processing, and wireless communications and networks. Practical problems with smart fabrics, biomonitoring and health informatics are all addressed, plus end user centric design, ethical and safety issues.
  • Bioimpedance and Bioelectricity Basics

    • 3rd Edition
    • Orjan G. Martinsen + 1 more
    • English
    Bioimpedance and Bioelectricity Basics, 3rd Edition paves an easier and more efficient way for people seeking basic knowledge about this discipline. This book's focus is on systems with galvanic contact with tissue, with specific detail on the geometry of the measuring system. Both authors are internationally recognized experts in the field. The highly effective, easily followed organization of the second edition has been retained, with a new discussion of state-of-the-art advances in data analysis, modelling, endogenic sources, tissue electrical properties, electrodes, instrumentation and measurements. This book provides the basic knowledge of electrochemistry, electronic engineering, physics, physiology, mathematics, and model thinking that is needed to understand this key area in biomedicine and biophysics.
  • Fossil Fungi

    • 1st Edition
    • Thomas N Taylor + 2 more
    • English
    Fungi are ubiquitous in the world and responsible for driving the evolution and governing the sustainability of ecosystems now and in the past. Fossil Fungi is the first encyclopedic book devoted exclusively to fossil fungi and their activities through geologic time. The book begins with the historical context of research on fossil fungi (paleomycology), followed by how fungi are formed and studied as fossils, and their age. The next six chapters focus on the major lineages of fungi, arranging them in phylogenetic order and placing the fossils within a systematic framework. For each fossil the age and provenance are provided. Each chapter provides a detailed introduction to the living members of the group and a discussion of the fossils that are believed to belong in this group. The extensive bibliography (~ 2700 entries) includes papers on both extant and fossil fungi. Additional chapters include lichens, fungal spores, and the interactions of fungi with plants, animals, and the geosphere. The final chapter includes a discussion of fossil bacteria and other organisms that are fungal-like in appearance, and known from the fossil record. The book includes more than 475 illustrations, almost all in color, of fossil fungi, line drawings, and portraits of people, as well as a glossary of more than 700 mycological and paleontological terms that will be useful to both biologists and geoscientists.
  • Emerging Technologies for Food Processing

    • 2nd Edition
    • Da-Wen Sun
    • English
    The second edition of Emerging Technologies in Food Processing presents essential, authoritative, and complete literature and research data from the past ten years. It is a complete resource offering the latest technological innovations in food processing today, and includes vital information in research and development for the food processing industry. It covers the latest advances in non-thermal processing including high pressure, pulsed electric fields, radiofrequency, high intensity pulsed light, ultrasound, irradiation, and addresses the newest hurdles in technology where extensive research has been carried out.
  • Sittig's Handbook of Pesticides and Agricultural Chemicals

    • 2nd Edition
    • Richard P. Pohanish
    • English
    This reference handbook provides fully updated chemical, regulatory, health, and safety information on nearly 800 pesticides and other agricultural chemicals. The clear, consistent and comprehensive presentation of information makes Sittig's an essential reference for a wide audience including first responders, environmental and industrial health/safety professionals, the food industry, the agricultural sector and toxicologists. Detailed profiles are provided for each substance listed, including: usage; crop-specific residue limits; hazard ratings for long-term human toxicity; and endocrine disruptor and reproductive toxicity information. Every chemical profile contains references and web links to source information from the EPA, OSHA, the World Health Organization (WHO), and other important advisory and lawmaking bodies. This work is focused on regulated chemicals. The substances covered include pesticides, insecticides, herbicides, fungicides, rodenticides and related agricultural chemicals used on foods grown and produced for both human and animal consumption. These products are organized with common names, chemical synonyms, trade names, chemical formulae, US EPA pesticide codes, EU regulations including Hazard Symbol and Risk Phrases, EINECS, RTECS, CAS, and other unique identifiers so that all who may have contact with, or interest in them can find needed information quickly.