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Elsevier

Books in Life sciences

  • Reproductive Immunogenetics: A Molecular and Clinical Overview, Vol. 3

    Immunogenetic Factors and Signaling Pathways in Recurrent Pregnancy Loss
    • 1st Edition
    • Shafat Ali + 2 more
    • English
    Immunogenetics: A Molecular and Clinical Overview, Vol. 3, Immune Cells and Immunotherapeutics in Recurrent Miscarriage provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In fifteen chapters, the book describes the roles of both helper cells, nature killer cells, lymphoid cells, regulatory cells and macrophages in recurrent pregnancy loss. In addition, it describes clinical outcomes of several therapies and gives insight into new treatments. This new release is a valuable resource for health professionals, scientists and researchers, and all those who wish to broaden their knowledge in the allied field.

  • Cell Migration in Development

    • 1st Edition
    • Volume 164
    • English
    Cell Migration in Development, Volume 163 highlights new advances in the field, with chapters written by an international board of authors who update on high-profile topics such as. Single-cell migration in development - lessons from germ-cells, Lipid/membrane regulation during cell migration and invasion, Remodeling of the extracellular matrix and cell-matrix adhesion during collective cell migration, From cessation of neural crest migration to onset of gangliogenesis, Collective migration in confined spaces: the case of trunk neural crest, From single to collective: the mechanisms underlying cell migration in early development, Direct and indirect roles of Nodal signaling in developmental cell migration.

  • Non-coding RNA

    • 1st Edition
    • Volume 214
    • English
    Non-coding RNA, Volume 214 in the Progress in Molecular Biology and Translational Science series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as An introduction to non-coding RNAs, Non-coding RNAs in Eutherians and Livestocks, Artificial intelligence and machine learning heuristics for discovery of ncRNAs in humans, Non-coding RNAs in Plants, Epigenetic and experimental approaches influencing ncRNAs, Noncoding RNAs in bacteria, Dissecting ncRNA pathways and omics integration, Structural prediction of potent ncRNAs, Artificial intelligence and machine learning heuristics for discovery of ncRNAs in humans, Tools and Databases for non-coding RNAs, and Physiogenomics and genetic landscape of ncRNAs.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 130
    • English
    Advances in Applied Microbiology, Volume 130 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • The Mastery of Bile Duct Injury

    • 1st Edition
    • Qalandar H. A. Kasnazani
    • English
    The Mastery of Bile Duct Injury is a comprehensive medical reference that explores the various aspects of biliary injuries, encompassing anatomy, causes, classifications, clinical management, and surgical procedures, with a particular focus on complications arising from laparoscopic cholecystectomy. It not only provides a meticulous dissection of biliary injuries but also navigates through the labyrinth of diagnostic modalities and therapeutic approaches, illuminating the path toward enhanced patient care, surgical precision, and the future of research in this area.Through its detailed examination, this authoritative reference serves as an invaluable resource for the complexities of biliary pathology empowering readers to navigate the challenges inherent in hepatobiliary surgery. Beginning with the historical evolution of cholelithiasis and extending to the impact of laparoscopic cholecystectomy, this book provides detailed insights into the intrahepatic and extrahepatic biliary systems, offering a foundation for understanding the complexities of biliary injuries encountered during surgical procedures.By addressing classification, management, and prevention strategies, this book serves as an invaluable resource for optimizing patient outcomes and minimizing complications in hepatobiliary surgeries. In a field where staying current with best practices is essential, The Mastery of Bile Duct Injury emerges as a vital reference, catering to the needs of surgeons, clinicians, and researchers alike. Its interdisciplinary approach and thorough examination of topics make it an indispensable resource for anyone involved in hepatobiliary surgery or seeking a deeper understanding of biliary injuries.

  • Bioinformatics Essentials

    Core Principles and Techniques
    • 1st Edition
    • Syed Mudasir Ahmad + 2 more
    • English
    Encompassing the foundational principles to advanced methodologies, Bioinformatics Essentials: Core Principles and Techniques offers a panoramic view of bioinformatics. It embarks on a journey that spans genes and genomes, sequence analysis, comparative genomics, functional genomics, and the exciting domain of protein structures and drug design. Spread over 3 parts and 7 chapters, the book describes the basic concepts in bioinformatics, genomic analysis, and ligand-based and structure-based drug designs. Each chapter is imbued with real-world context, demonstrating the practical implications of bioinformatics. Case studies, examples, and hands-on guides bridge the gap between theory and application, enabling readers to translate knowledge into tangible results. It fosters a holistic understanding of bioinformatics as an interdisciplinary field, acknowledges the evolving nature of bioinformatics, and prepares the readers for the future. Discussions on emerging trends, cutting-edge tools, and potential directions in the field of bioinformatics equip readers to stay at the forefront of advancements. Insights from both biology and computational science converge to provide a well-rounded perspective on the complex biological systems. While designed as a comprehensive guide for learners, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within bioinformatics.

  • Cheese

    Chemistry, Physics and Microbiology
    • 5th Edition
    • Paul L.H. McSweeney + 3 more
    • English
    Cheese: Chemistry, Physics and Microbiology, Fifth Edition provides a comprehensive overview of the chemical, biochemical, microbiological, and physico-chemical aspects of cheese, taking the reader from the rennet and acid coagulation of milk to the role of cheese and related foods in addressing public health issues. This updated revision, the most comprehensive work on the science of cheese, addresses the basic definition of cheese, along with the diverse factors that affect its quality. Understanding these fermented milk-based food products is vital to a global audience.Divided in two volumes, this book contains by far the most comprehensive coverage of the scientific aspects of this important dairy product, covering all aspects of cheese manufacture and ripening from the standpoint of basic science (vol 1). In addition, coverage is included of all major families of cheese (vol 2).

  • Role of Antioxidants in Mitigating Plant Stress

    • 1st Edition
    • Azamal Husen
    • English
    Role of Antioxidants in Mitigating Plant Stress explores the fundamental roles and mechanistic approaches of antioxidant stress tolerance strategies. With chapters addressing both enzymatic and non-enzymatic antioxidants, it provides a clear guide for understanding plant responses. Presenting current understanding of these components, the book features their role, molecular properties, and reaction mechanisms to various environmental conditions. This book provides an important reference for researchers and advanced level students seeking to improve plant health.Plants are regularly exposed to various kinds of abiotic and biotic stresses in their natural environmental conditions. These stresses have significant influence on agriculture worldwide and thus, lead to massive economic losses as well as food insecurity. Research has identified many of the effects of, and mitigation techniques for, various stresses that impact plant systems. Strategies for strengthening the antioxidant defense system can increase yields and protect crop plants from a variety of stresses.

  • Learning and Memory: A Comprehensive Reference

    • 3rd Edition
    • John T. Wixted
    • English
    Learning and Memory: A Comprehensive Reference, Third Edition, Four Volume Set is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition includes chapters that reflect the rapidly evolving state-of-the-art for research in this area, from the molecular mechanisms of consolidation and forgetting to the cognitive mechanisms of eyewitness memory. No other reference work comes close to providing so much depth, hence this is a valuable tool for all academics and researchers in the field of neuroscience, psychology, psychiatry, neurobiology and neurology.

  • Mitochondria and Neurotoxicity

    • 1st Edition
    • Volume 13
    • English
    Mitochondria and Neurotoxicity, Volume Thirteen in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Introduction to mitochondrial toxicity: form, function, and signaling, Respirometry parameters as indicators of neurotoxicity, Pesticide exposure and hippocampal neurogenesis: Role of ER stress and mitochondria, Gene Therapy Approaches to Abrogate Pathogenic Mechanisms in Parkinson’s disease, Mitochondrial dysfunction induced by trichloroethylene in Parkinson’s disease, and Gut-brain axis inflammation induced by mitochondrial toxicants.

  • Psychedelics in Psychiatry

    • 1st Edition
    • Volume 181
    • English
    Psychedelics in Psychiatry, Volume 181, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new volume include History of psychedelic drug science and molecular pharmacology, Pharmacological mechanisms and neuroplastic potential of non-psychedelic agents, Anti-inflammatory activity, Translational approaches for investigating the effects of psychedelics on cognitive and affective behaviors in rodents, Clinical pharmacology, Human neuroimaging fMRI, and more.Other chapters in this new release include Effects of psychedelics on human oscillatory brain activity, Molecular neuroimaging of psychedelic drug effects, Neurobiology of sub-psychedelic doses, Depression and related disorders, Addictions, Trauma disorders, Neurological disorders, and Challenges to the developing field of psychedelic medicine - political and ethical considerations and commercialization of therapy.

  • Cerebral Metastases: Translational Advances, Evaluation and Management

    • 1st Edition
    • Volume 165
    • English
    Cerebral Metastases: Translational Advances, Evaluation and Management, Volume 165 in this ongoing series, highlights new advances in the field, with this new volume covering many interesting topics, including Molecular Drivers in CNS metastasis, Role of the tumor microenvironment in CNS metastatic disease, Advanced Imaging to improve early diagnosis and evaluate treatment response, Liquid biopsy in early detection of CNS metastasis, Precision medicine approaches to CNS metastatic disease, IMRT/conventional RT, Single and hypofractionated SRS, Brachytherapy for recurrent metastases, LITT for treatment of active brain metastasis and radiation necrosis, and much more.Other topics covered include Minimally-invasive surgical approaches in the management of brain metastases.

  • Artificial Intelligence Innovations for Biomedical Engineering and Healthcare

    • 1st Edition
    • Alma Y Alanis + 3 more
    • English
    Artificial Intelligence Innovations for Biomedical Engineering and Healthcare bridges the evolving domains of artificial intelligence and biomedical engineering and healthcare. In an era where data-driven insights and precision medicine are essential in healthcare, this book explores emerging trends and showcases AI's potential in transforming patient care, diagnosis, and the treatment of chronic diseases. It simplifies the relationship between artificial intelligence and biomedical engineering, elucidating how these technologies are revolutionizing self-care. The book goes on to examine how advanced technologies, including complex networks and AI-driven diagnostics are reshaping the healthcare landscape.From decoding complex networks to revealing AI's role in treating chronic diseases, this book serves as a guide to understanding how innovation is reshaping the healthcare landscape.

  • Advances in Probiotic Delivery Systems

    Strategies for Enhanced Viability, Targeted Delivery and Efficacy
    • 1st Edition
    • Tanmay Sarkar + 2 more
    • English
    Advances in Probiotic Delivery Systems: Strategies for Enhanced Viability, Targeted Delivery and Efficacy covers the complex world of probiotics, offering a comprehensive exploration of innovative delivery mechanisms designed to overcome challenges of stability and efficacy. From oral administration to alternative delivery routes, each chapter provides insights into cutting-edge formulation strategies, encapsulation techniques, and emerging technologies, equipping readers with the knowledge to explore the full potential of probiotics for health and wellness. Bridging the gap between theory and practice in probiotic delivery systems, this book delivers insights into the most effective delivery strategies.Despite the growing interest in probiotics and their potential health benefits, challenges such as poor stability and limited efficacy hinder their widespread application. This book fills this critical gap by providing readers with a thorough understanding of the underlying principles, latest advancements, and practical solutions in probiotic delivery. By consolidating the expertise of leading researchers and practitioners, the book empowers professionals across various industries to develop and implement effective probiotic formulations that make a difference in health outcomes.

  • Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology

    • 1st Edition
    • Muhammad Ishfaq
    • English
    Computational Methods in Medicinal Chemistry, Pharmacology, and Toxicology is a comprehensive resource that offers an advanced overview of computational techniques employed in drug discovery, design, and toxicity prediction. The book discusses various topics, including molecular modeling, virtual screening, machine learning, and network pharmacology. It serves as an essential guide for researchers, practitioners, and students in pharmacology, toxicology, medicinal chemistry, bioinformatics, and systems biology fields, showcasing practical applications and future perspectives on new technologies. In addition to covering computational approaches, the book provides real-world examples of drug discovery, candidate optimization, and safety assessment.Other sections explore computer applications in pharmacology and toxicology and discusses the importance of these methods in advancing medicinal research.

  • Lignin-Degrading Enzymes

    • 1st Edition
    • Volume 716
    • English
    Lignin-Degrading Enzymes volume 716 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • 3D Bioprinting in Cancer Applications

    • 1st Edition
    • Fahima Dilnawaz + 3 more
    • English
    3D Bioprinting in Cancer Applications is an all-encompassing guide covering both fundamentals concerning biofabrication principles and intricate protocols for precise construction of biomimetric 3D systems supporting advanced cell culture development that faithfully recapitulates human disease hallmarks, with a special focus on cancer. This title fills the void left by existing publications overlooking essential aspects associated with combining multimodal medical imaging alongside precision cancer treatment options. In 12 chapters 3D Bioprinting in Cancer Applications leads the reader from an introduction to bioprinting technologies for cancer models, to models for immunotherapy and tumour-immune interaction, to biomimetrics 3D models to the applications of all these models in 3D bioprinted cancer models . 3D Bioprinting in Cancer Applications uniquely combines distinct modalities under a unified framework suitable not only for seasoned veterans but also newly minted trainees encountering these sophisticated practices for the first time.

  • Encyclopedia of the Neurological Sciences

    • 3rd Edition
    • John D. England
    • English
    Major advances in neurobiology and the clinical neurosciences have occurred in the past decade. Encyclopedia of the Neurological Sciences, Third Edition, Seven Volume Set, will cover and review all major areas of neuroscience and will be one of the few publications that can provide a complete overview of the neurological sciences in an easily accessible electronic format. All 21 sections and approx. 500 chapters will contain extensive supplemental links to useful references. Of special note are the new and paradigm shifting developments in genetics, immunology, molecular neurobiology, neuro-diagnostic tools and therapies for neurological disorders. This new edition will provide a thorough and easily accessible update in all areas of the neurological sciences. The sections and chapters will be written by internationally recognized experts from around the world and will be a valuable resource for all researchers, students and established scientists in the fields of neurology, psychiatry, and neurosurgery.

  • Farmacología humana

    • 7th Edition
    • Jesús Flórez Beledo + 2 more
    • Spanish
    La séptima edición de "Farmacología humana", obra de referencia de la especialidad en habla hispana, ofrece un texto exhaustivo y plenamente actualizado, guiado por la claridad expositiva y combinando el conocimiento teórico con la práctica clínica. Se han mantenido y reforzado los capítulos que abordan los principios básicos de la ciencia farmacológica y se han reflejado todas las novedades acontecidas desde la última edición y se ha incluido un nuevo capítulo dedicado a las "Terapias antoneoplásicas dirigidas". Otra novedad a destacar es la incorporación de nuevos colaboradores que junto con los ya tradicionales aúnan experiencia y frescura a esta magnífica obra.

  • Developmental Dyscalculia

    From Brain Mechanisms to Educational Applications
    • 1st Edition
    • Yarden Gliksman + 2 more
    • English
    Developmental Dyscalculia: From Brain Mechanisms to Educational Applications presents research with a domain-general approach. It examines issues in the fields of numerical and non-numerical cognitive domains, neuro- mechanisms, and pedagogic issues to pave the way to a bridge between lab research, daily life, and curriculum applications, with a goal of finding a pathway to early diagnosis and interventions of developmental dyscalculia. It will be of interest to researchers with interests in cognitive neuroscience and education, to contribute fruitful discussions between education and neuro-cognition. 

  • Plant-Based Milk Alternatives and Human Health

    Current Trends, Nutrition, and Public Health Implications
    • 1st Edition
    • Hassan Vatanparast
    • English
    Plant-Based Milk Alternatives and Human Health: Current Trends, Nutrition, and Public Health Implications covers plant-based milk alternatives and their impact on human health and nutrition. The book includes information on global national dietary recommendations, consumption trends, and public health concerns, and draws economic and health comparisons between conventional dairy milk and plant-based milk alternatives. Additional topics included are the history and commercialization of plant-based milks, their role in ethical issues, their influence on social well-being, and their impact on agriculture, business, and economics. Finally, the authors present projections for the future role and impact of plant-based milk alternatives in a global setting.This reference will be of particular interest to researchers in nutrition, food and beverage science, and public health who focus on dairy milk and milk alternatives, beverage companies and product developers in the non-dairy milk space, as well as governmental organizations that provide health recommendations.

  • Psychopharmacologie pratique

    Transposer les résultats des essais fondés sur les preuves dans la pratique clinique
    • 1st Edition
    • Joseph F. Goldberg + 2 more
    • French
    Aujourd’hui, la polypharmacologie est un outil majeur pour le traitement des patients souffrant de formes graves et chroniques de troubles de l’humeur, d’anxiété, de psychose ou de troubles du comportement.Dans l’esprit des travaux et écrits de Stephen M. Stahl, cet ouvrage offre une vue d’ensemble novatrice sur les connaissances en psychopharmacologie et les stratégies de prises de décision, en intégrant les résultats d’essais fondés sur les preuves aux données de la clinique, avec des exemples et des situations cliniques réelles. Il aborde la manière dont les prescripteurs peuvent mettre en place une « psychopharmacologie sur mesure », adaptée aux besoins spécifiques de chaque patient, en conservant l’approche et l’état d’esprit d’un praticien.Quelle que soit leur expérience, les professionnels pourront ainsi affiner et améliorer leurs prescriptions et leurs prises en charge, en ciblant les manifestations des circuits neuronaux dysfonctionnels et les dimensions psychopathologiques, au-delà des diagnostics psychiatriques conventionnels.Prése... sous une forme dynamique, pratique et en couleurs, avec des tableaux de synthèse, des encadrés et des vignettes cliniques concrètes, cet ouvrage est un guide précieux d’aide à la décision pour tous les praticiens qui prescrivent des psychotropes. Joseph F. GoldbergProfesseur de psychiatrie clinique,Icahn School of Medicine at Mount Sinai, New YorkStephen M. StahlProfesseur de psychiatrie et de neurologie,Universit... of California Riverside and University of California San DiegoMarc-Antoine Crocq (traducteur)Psychiat... des adolescents du Haut-Rhin, CAMUHA,Université de Haute-Alsace, Mulhouse

  • Rice Cultivation Under Abiotic Stress

    Challenges and Opportunities
    • 1st Edition
    • Sudhakar Srivastava + 2 more
    • English
    Rice Cultivation under Abiotic Stresses: Challenges and Opportunities provides a unique look at three key factors in optimized rice yield – cultivation practices, understanding abiotic stress response, and mitigation strategies – enabling the reader to better understand the cause, effect, and means of protecting rice crop yield. It is a uniquely comprehensive resource for advancing the sustainable and optimal production of rice that will be a valuable resource for researchers and advanced students in Agriculture, Agronomy, Botany, Plant Physiology, and Environmental Science.Rice is the primary source of energy for over half of the world’s people. It can play a vital role against mal and under nutrition, but as climate and other abiotic challenges continue to impact yield, steps need to be taken to ensure production.

  • Le Métabolisme humain et sa régulation
    • 1st Edition
    • Rhys D. Evans + 2 more
    • French
    La collection « Elsevier Monographies » permet aux praticiens d’approfondir et d’actualiser leurs connaissances, en exposant les données fondamentales actuelles et leurs applications dans la pratique clinique. Traduit de la 4e édition anglaise, cet ouvrage offre un exposé complet et actualisé du métabolisme humain et de sa régulation. Les auteurs explicitent des concepts difficiles avec des termes clairs et concis afin de fournir un guide accessible et utile sur ce sujet. Cet ouvrage complet couvre un large éventail de thèmes, tels que la balance énergétique, la régulation du poids corporel, l’exercice et la façon dont l’organisme fait face à des situations extrêmes, et montre comment les mécanismes de régulation du métabolisme permettent à l’organisme de s’adapter à de nombreuses situations différentes.Incluant les connaissances les plus récentes, l’ouvrage est largement illustré pour faciliter la compréhension des mécanismes de régulation par lesquels toutes les cellules contrôlent les processus métaboliques nécessaires à la vie, avec la mise en regard des voies du métabolisme et des principales maladies métaboliques. L’ouvrage comprend des résumés des chapitres et des informations complémentaires pour approfondir les notions ainsi que des questions interactives en ligne.Ce guide indispensable est donc un outil précieux pour les scientifiques, les praticiens et les étudiants des sciences de la santé, notamment en médecine, en pharmacie, en biochimie, en nutrition, en diététique… POINTS CLÉSRégulation et intégration du métabolismeSpécialis... métabolique des organes et des tissusPhysiopatholog... du métabolisme Keith N. Frayn est professeur émérite, spécialiste en médecine métabolique dans le département de médecine Radcliffe, à l’Université d’Oxford (Royaume-Uni).Rhys D. Evans est maître de conférences en biochimie métabolique dans le département de Physiologie, anatomie et génétique de l’Université d’Oxford (Royaume-Uni) et médecin consultant en anesthésie et soins intensifs au NHS Trust – Hôpitaux Universitaires d’Oxford, hôpital John Radcliffe à Oxford (Royaume-Uni).Éric Raynaud de Mauverger est biologiste médical et Professeur des Universités-Praticie... Hospitalier à l’Université et au CHU de Montpellier (France).

  • Primer Design

    • 1st Edition
    • Volume 57
    • English
    Primer Design, Volume 57 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Methods on discriminating between bacterial strains, Primers to PCR and qPCR techniques, and more.

  • Innovations in Cardio-Oncology

    Artificial Intelligence, Digital Health, and Precision Medicine
    • 1st Edition
    • Sherry-Ann Brown
    • English
    Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine reviews the benefits of biomedical technologies and advancements in individualized medicine, with applications in cardio-oncology.Illu... of work involving machine learning and natural language processing help readers understand and maximize the benefits of artificial intelligence (AI) algorithms, with integration of AI and digital health technologies into the clinical workflow for personalized patient care, research, and provider and patient education.In 31 chapters, Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine introduces the emergent medical field at the interface of cardiology and oncology, “cardio-oncology”, and describes prevention, screening and surveillance, followed by several chapters on the role of the applications of digital health, telemedicine, and AI in cardio-oncology precision care. The book also highlights many medical society guidelines and evidence-based recommended pathways for equitable digital health deployment and utilization in cardio-oncology care. This book anticipates that AI algorithms and innovative health tools have the potential to address, and does not have to widen, the already existing healthcare disparities, including inequalities related to race, ethnicity, gender, socioeconomic level, health insurance status, linguistic and cultural barriers, systemic discrimination, and healthcare access.This book provides valuable practical guidance for healthcare professionals, scientists, learners, and patients to integrate digital health platforms into their clinical practice, research, and patient engagement models, fit for individual use and also for multi-stakeholder groups from academia, technology, and industry, with shared interests in applying Innovation (Digital Health, mHealth, Telemedicine, Telehealth, Informatics, Precision Health, Computational Medicine, Social Media, Artificial Intelligence including Machine Learning, Deep Learning, Natural Language Processing, and Neural Networks, & more) to Cardiology and Oncology clinical practice, research, and education.

  • Translational Pulmonology

    • 1st Edition
    • English
    Translational research is essential to the advancement of medicine. Translational Pulmonology is an instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in pulmonary diseases, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

  • Advances in DNA and mRNA-Based Strategies for Cancer Immunotherapy: Part A

    • 1st Edition
    • Volume 165
    • English
    Advances in DNA and mRNA-Based Strategies for Cancer Immunotherapy, Volume 165 in the Advances in Immunology series, presents current developments and comprehensive reviews in DNA and mRNA vaccines: Significant therapeutic approach against cancer management, Nanoparticles for mRNA-based cancer immunotherapy, Nucleic acid Delivery as a therapeutic approach in cancer immunotherapy, Plasmid DNA and mRNA: Delivery approaches and challenges, Viral & Non-viral Delivery of mRNA against Cancer Cell, Progress in Modifying and Delivering mRNA therapies for Cancer Immunotherapy, and more.Other chapters cover mRNA-Based Cancer Vaccines: A Novel Approach to Melanoma Treatment, Therapeutic mRNAs for cancer immunotherapy: from structure to delivery, Harnessing the immune system: Insights into cancer vaccines, Lipid Nanoparticle-Mediate... mRNA Delivery in Cancer Immunotherapy, Immunotherapy Perspectives in the Era of B-Cell Editing in Cancer Treatment, Personalized Precision: Revolutionizing Cancer Treatment with mRNA-Based Vaccines in Melanoma Therapy, Revolutionizing Cancer Treatment: Exploring Novel Immunotherapeutics, Checkpoints, bispecifics, and Vaccines in Development, and more.

  • Application of Adult Stem Cells in Regenerative Medicine

    • 1st Edition
    • Farshid Sefat + 1 more
    • English
    Application of Adult Stem Cells in Regenerative Medicine offers a comprehensive overview of tissue engineering using adult stem cells to treat various disorders throughout the human body. The book introduces readers to adult stem cells, tissue engineering, and their application in regenerative medicine. It covers many new and up-to-date techniques, providing a solid foundation for understanding the field. Written by global leaders, this resource is invaluable for anyone studying, researching, or working in the areas of adult stem cells, tissue engineering, or regenerative medicine.The book is divided into three parts. Part One provides an introduction to adult stem cells and their application in regenerative medicine. Part Two focuses on different body organ systems, including the nervous, respiratory, digestive, urinary, circulatory, endocrine, skeletal, reproductive, muscular, and ocular systems. Part Three concludes with a review of the future of adult stem cells in regenerative medicine. This structure ensures that readers gain a thorough understanding of the current state and future potential of adult stem cells in treating various disorders.

  • Additive Manufacturing Solutions for Advanced Veterinary Practice

    Clinical Dentistry, Orthopedic, and Drug Delivery Methods
    • 1st Edition
    • Rupinder Singh + 2 more
    • English
    Additive Manufacturing Solutions for Advanced Veterinary Practices: Clinical Dentistry, Orthopedic, and Drug Delivery Methods highlights cost- and time-saving 3D printing methods and materials for application on a broad array of veterinary patients and procedures. Additive manufacturing of sensors, biodegradable dental implants, smart dental implants, joint implants, and drug-delivery materials are each covered, as are biomimetic, augmented reality, and virtual reality approaches. Varied additive manufacturing processes and techniques are covered, with each chapter including at least one case study that shows the material covered being put into practical use.

  • Sustainable Applications of Pomegranate Peels

    • 1st Edition
    • Mejdi Jeguirim + 1 more
    • English
    Sustainable Applications of Pomegranate Peels serves as an invaluable resource to enhance pomegranate farming and fruit processing industries while minimizing environmental impacts. The book delves into multiple sustainable applications, spanning biotechnological, agricultural, environmental, and energy sectors. It provides in-depth identification, quantification, and characterization of pomegranate wastes along with their potential in livestock breeding. Notably, it explores the use of bioactive compounds from by-products in food products, and details pomegranate's health benefits, including antioxidant and antimicrobial properties. This comprehensive guide is essential for researchers, decision-makers, and industry professionals.

  • The Neuroscience of Feelings

    Unveiling the Mind-Brain Alchemy
    • 1st Edition
    • Volume 293
    • English
    The Neuroscience of Feelings: Unveiling the Mind-Brain Alchemy focuses on exploring the complex interplay between emotions and brain function, covering topics such as how positive and negative feelings impact brain cell regeneration, the influence of emotions on decision-making, and the role of emotional trauma in brain health. The book aims to provide comprehensive insights into how different emotions shape neurological processes, contributing to mental and physical health.

  • Microbiome in Neurological Conditions: Biology, Mechanisms, and Diagnostic Approach

    • 1st Edition
    • Volume 180
    • English
    Microbiome in Neurological Conditions, Volume 180, the latest release in the International Review of Neurobiology series, highlights advances in the field, with this volume presenting insightful chapters written by an international board of authors. Chapters in this volume include Dysbiosis significantly elevates the probability of altered affective function in Alzheimer's Disease (AD), Intestinal Dysbiosis leads to reduction in Neurochemical production in Parkinson’s Disease (PD), Microbiota dysbiosis impact on the immune system dysregulation in Huntington's disease (HD), Altered microbiome influence on the enteric neuromuscular system in Amyotrophic Lateral Sclerosis (ALS), Oro-pharyngeal mucosal microbiome alterations causing immune system dysregulation in Schizophrenia, and much more.Other chapters cover Disruption in the human microbiome causing behavioral changes in Bipolar Disorder, The role of Microbiome in Gut-Brain-Axis dysbiosis causing Depression: from Mechanisms to Treatment, Microbial imprints: The role of secondary genomes in neurodevelopment and co-evolutionary dynamics, Abnormal microbiota due to perinatal antibiotic exposure as a possible risk factor for Attention-Deficit / Hyperactivity Disorder (ADHD), Microbiome-based dietary supplements for better development and a healthy brain, Bacterial meningitis as a significant catalyst for neuroinflammation, and more.

  • Encyclopedia of the Eye

    • 2nd Edition
    • Patricia D’Amore
    • English
    Encyclopedia of the Eye, Second Edition, Four Volume Set is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology, and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea, and lens. The book also covers the physiological and pathophysiologic processes that affect all eye tissues. Each chapter addresses one specific structure or process, reviews basic concepts, cross-references other chapters within the Encyclopedia, and provides citations of relevant primary publications.It is an invaluable resource for undergraduate students, graduate students, postdoctoral fellows, medical students, and residents seeking an introduction to an area of eye research. It will be particularly useful for visual scientists and practitioners who are investigating a new area, seeking deeper understanding of important research articles in fields adjacent to their own, and/or reviewing a grant or manuscript outside their immediate area of expertise.

  • Formation and Fate of Cell Organelles

    • 1st Edition
    • Katherine Brehme Warren
    • English
    Formation and Fate of Cell Organelles is a collection of papers that discusses the manner in which cellular structures arise from the component molecules, particularly on cytoplasmic inheritance, and the problem of spontaneous assembly. One paper describes the process how the phospholipid lecithin, assemble spontaneously into complex structures with great versatility when the lipid molecules are dispersed in an aqueous environment in vitro. Another paper discusses the resolution of the spindle fibers of the mitotic apparatus where the major protein in the apparatus is a 3.5 S particle, with a molecular weight of ca. 68,000. One paper investigates the degree of organization in the bacterial cell where inside the bacterial cell, the DNA act as its own method of compartmentation. Possibly, the DNA forms a coil which contains the mechanisms for the synthesis of the deoxy triphosphate into DNA. The coil leaves none of the mechanisms for the normal metabolism of the cell nor the mechanisms for the formation of RNA. Another paper examines cytoplasmic genes and organelle formation. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

  • Parkinson's Disease, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-2
    • Joseph Jankovic
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Joseph Jankovic brings his considerable expertise to the topic of Parkinson's Disease. Top experts cover key topics in the field, including James Parkinson and other historical aspects of Parkinson’s disease; precision medicine in Parkinson’s disease; prodromal Parkinson’s disease; biomarkers in Parkinson’s disease; disease-modifying therapies in Parkinson’s disease; and many more.

  • Lung Cancer and Environmental Toxicants

    • 1st Edition
    • Kamal Dua + 4 more
    • English
    Lung Cancer and Environmental Toxicants aims to explore the intricate relationship between lung cancer and environmental toxicants, shedding light on a hidden link that demands urgent attention. This groundbreaking book addresses a critical gap in the current literature by introducing a pioneering exploration of the interplay between lung cancer and environmental toxicants. Previous articles have not coalesced into a comprehensive examination of the complex connection between lung cancer development and the diverse array of environmental toxicants. This book delves into the latest scientific research and clinical findings to offer a clear way forward for healthcare workers to assess and treat lung cancer patients who may have been exposed to these substances. "Lung Cancer and Environmental Toxicants" provides a precise view of the impact of environmental toxicants on lung cancer, covering various aspects including epidemiology, molecular mechanisms, exposure pathways, and preventive measures. This unique and timely work will pave the way for a deeper understanding of the underexplored factors contributing to lung cancer incidence, offering novel insights into the role of various toxic substances in disease causation. This significant title will catalyze new avenues of research and awareness in the fields of oncology, environmental health, and public policy.

  • Anti-Prostate Cancer Agents

    • 1st Edition
    • Qiao-Hong Chen
    • English
    Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications... This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents.This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degrader... So far, no book focusing on the topic has been published.

  • Biomarker Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Biomarker Landscape in Cancer Research examines the impact of early detection, predication of aggressiveness, and the determination of the best treatment for cancers. With a strong focus on the status, challenges, and prospects of biomarker measurements' tools and technology, the book also examines clinical translation-related knowledge and the prognosis of different organ related cancers. In 21 chapters, it describes current and new diagnostic tools in twenty different cancers and explores how innovations in the cancer diagnostic space could make cancer screening and early detection more straightforward.This book is a timely and valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Raising Genomics Literacy, Knowledge, and Awareness

    • 1st Edition
    • Azhar T. Rahma + 1 more
    • English
    Raising Genomics Literacy, Knowledge, and Awareness is a unique resource which describes the importance of genomic literacy for the effective and streamlined implementation of genomic medicine and pharmacogenomics globally. It provides evidence and expert opinion to decipher the role of genomic and pharmacogenomic literacy to illustrate the evidence, value, and need of raising genomics awareness and education among healthcare professionals, students, and the general public. This text can be used by researchers and graduate students pursuing research in this area.

  • Blindness and Visual Impairments

    • 1st Edition
    • Volume 292
    • English
    Blindness, Volume 292 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Temperature as a circadian timing cue in the visually impaired, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Measuring residual visual function after cerebral damage – a potential path for optimizing rehabilitation approaches, and Persistence of training-induced visual improvements after occipital stroke, amongst other topics.Other chapters in this release include Well-being, mental health, and sleep in children and young people with vision impairment: A narrative review, Changes to the brain due to visual impairment, Information Processing in People with Visual Impairments, Case studies of the migraine aura in the blind or partially sighted, HABEMO: an innovative haptic tool for investigating the bodily representation of mental states in individuals with visual impairments, and Affect in the dark: navigating the complex landscape of social cognition in blindness, and An overview of quality of life and visual outcomes in AMD.

  • Novel Genetic Pathways Associated to Energy Homeostasis Impairments

    • 1st Edition
    • Volume 113
    • English
    Novel Genetic Pathways Associated to Energy Homeostasis Impairments, Volume 113 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Advances in Metabolism: Energy Balance Circuitry, Advances in Metabolism: Diabetic Retinopathy, From Metabolomics to Energy Balance Physiology, Advances in Metabolism: Prader-Willi Syndrome, Neural Mechanisms and Health Implications of Food Cravings During Pregnancy, Advances in Metabolism: Diabetes, Advances in Metabolism: Cachexi, and Parkinson’s Disease and Metabolic Disorders: Understanding Their Shared Co-Morbidity Through the Autonomic Nervous System.

  • Circadian Rhythms in Health and Disease

    • 1st Edition
    • Volume 393
    • English
    Circadian Rhythms in Health and Disease, Volume 393 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Circadian Rhythms in Cardiac Health and Disease, Liver as a nexus of daily metabolic cross talk, Non-rhythmic modulators of the circadian system: A new class of circadian modulators, The emerging role of circadian rhythms in exosome-mediated cellular crosstalk, Circadian rhythms and muscle health, and Output circuits from the suprachiasmatic nucleus controlling diverse physiological functions.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 86
    • English
    Advances in Microbial Physiology, Volume 86, the latest release in this ongoing series, continues the tradition of topical, important, cutting-edge reviews in microbiology. The editors have always strived to view microbial physiology in the broadest sense. In this volume, chapters deal with Diversity in the physiology and metabolism of chlorophototrophic bacteria, Copper homeostasis in Streptococcus and Neisseria: known knowns and unknown knowns, A Lysis Less Ordinary: The Bacterial Type 10 Secretion System, Cytochrome bd-type oxidases and environmental stressors in microbial physiology, and Multiple roles for iron in microbial physiology: bacterial oxygen sensing by heme-based sensors.

  • Diabetes Mellitus

    Target Enzymes and Drugs
    • 1st Edition
    • Manisha Nidhar + 1 more
    • English
    Diabetes Mellitus: Target Enzymes and Drugs highlights the importance of different targets in lead drug discovery and the importance of the synthesis of lead analogues. The book discusses the role of target enzymes, receptors, and related drugs in diabetes mellitus that are necessary for research on improving solutions for diabetes care. This unique resource provides information about all enzymes or receptors involved in diabetes pathophysiology to help describe target enzymes and potent antidiabetic drugs to improve patient care.This type of research is needed for the understanding of the effects of drugs in order to improve future treatments and care of patients with diabetes.

  • The Living Laboratory for Precision Medicine

    Solutions for Clinical Implementation
    • 1st Edition
    • Dame Anna Dominiczak + 2 more
    • English
    The Living Laboratory for Precision Medicine: Solutions for Clinical Implementation provides a comprehensive resource on precision medicine through a convergence of innovation and solutions across multiple domains, including large population cohorts, artificial intelligence, genomics, phenomics, clinical trials, health economics and regulation exemplified by the living lab concept. This book is the first to look at precision medicine through the lens of last-mile solutions which make it broad in scope, practically relevant, and cutting-edge. The book explores the use of precision medicine to stimulate regional economic growth through a healthier population, savings on healthcare, and using innovation as a driver of economic development. The term precision medicine has been popularized by clinical, scientific, political, financial and technological interests as the biggest innovation to revolutionize healthcare. While over the past decade a few precision medicine-based solutions have come to fruition, the transformative leap in healthcare delivery and population benefit is yet to be realized. Current focus on precision medicine primarily focuses on patient stratification which constrains it to either a single disease area, a few sub-disciplines, or using a limited set of genomic technologies. While useful, experience over the last few years indicates precision medicine needs to be considered as a complex process with multiple feedback loops requiring significant interdisciplinary collaboration and innovation.

  • Carbohydrate Nutrition

    • 1st Edition
    • Bin Zhang + 1 more
    • English
    Carbohydrate Nutrition discusses the nutritional functionality of foods in addressing the current metabolic disease epidemic. It begins by introducing the sources and structures of various carbohydrates, including starch, human milk oligosaccharides, polyols, arabinoxylan, beta-glucan, and cellulose, along with their function in the small intestine and colon. The book offers a comprehensive examination of carbohydrates, covering their chemistry, classification, digestion and health implications. The importance of prebiotic carbohydrates, such as human milk oligosaccharides and dietary fibers like cellulose, arabinoxylans, and beta-glucan is also discussed.Each chapter is authored by leading experts in the field making Carbohydrate Nutrition is a valuable resource for nutrition researchers, food scientists, food chemists, and those studying related topics. Readers can apply these insights to the design and development of foods with improved carbohydrate nutrition.

  • Neuropathology of Aging and Alzheimer’s Disease

    • 1st Edition
    • Rudy J. Castellani
    • English
    Neuropathology of Aging and Alzheimer’s Disease takes a foundational approach to the topic by offering basic scientific information and the latest advancements in the field. The focus of this reference is on neuropathology and recent advances in tissue characterization in aging, and in Alzheimer’s Disease. Neuropathology has direct relevance to therapeutic constructs and allows for an in-depth understanding of disease pathogenesis. It is a synthesis of the salient issues with respect to pathology, pathogenesis, diagnosis, disease, normal aging, biomarker relevance, and prospects for therapeutic intervention.

  • Advances in Agronomy

    • 1st Edition
    • Volume 192
    • English
    Advances in Agronomy, Volume 192, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors. Chapters in this new release include The USDA Desert Soil-Geomorphology Project (1957-1972), Electrochemical transformations of nutrients in the soils vis-a-vis geochemistry of potentially and readily available nutrients under different soil moisture regimes: a review, Current approaches in the characterization and quantification of soil crusts, Soil fauna impacts on carbon cycling in managed grasslands: a review, Deciphering PGPR Mechanisms in Saline Soils: Enhancing Plant Productivity, and much more. Other chapters cover Interventions of microbial fuel cell technology for management of agricultural residues: Challenges and future perspectives.

  • Enzymes of Polyamine Metabolism

    • 1st Edition
    • Volume 715
    • English
    Enzymes of Polyamine Metabolism, Volume 715 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Convergence of MYC and the hypusine circuits in the control of metabolism, HDAC10 structure and enzymology, TR-FRET Assay for Profiling HDAC10 Inhibitors and PROTACs, Polyamine Transport Inhibitors: Methods and caveats associated with measuring polyamine uptake in mammalian cells, Evaluation of platinum drug toxicity resulting from polyamine catabolism, Measurements of acrolein adducts resulting from polyamine catabolism, Alterations in polyamine metabolism induced by the pathogen Helicobacter pylori: implications for gastric inflammation and carcinogenesis, and much more.Other sections delve into Molecular and biochemical analysis of eIF5A, Analysis of in vivo SMOX activity, Structure and role of ATP13A2 in polyamine transport, Analysis of Translational Regulation Using Polysome Profiling and Puromycin Incorporation, Targeting polyamine metabolism in an ex vivo prostatectomy model, Development and characterization of a Drosophila model of SRS, Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples, Gene replacement therapy to restore polyamine metabolism, Investigation of polyamine metabolism in bone homeostasis, Collection, preparation, and biobanking of clinical specimens for polyamine analysis, and many other topics.

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