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Vestibular Schwannomas
- 1st Edition, Volume TBD - June 1, 2026
- Editors: Simon Lloyd, Omar Pathmanaban, Gareth Evans
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 3 4 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 9 9 7 - 4
Vestibular schwannomas are the most common tumors of the cerebellopontine angle (CPA), the junction between the cerebellum and the brainstem. They constitute around 8% of intracran… Read more
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Request a sales quoteVestibular schwannomas are the most common tumors of the cerebellopontine angle (CPA), the junction between the cerebellum and the brainstem. They constitute around 8% of intracranial tumors. They are benign and arise from the vestibular nerve within the internal auditory canal growing from the canal into the CPA eventually causing brainstem compression. Their incidence is around 2.5 per 100,000. Around 70% of tumors do not grow following diagnosis but those that do or those that are already large at presentation are usually treated either with stereotactic radiosurgery or microsurgical resection.
Vestibular schwannomas have been extensively investigated over the years with nearly 10,000 peer reviewed papers relating to them on Pubmed. Despite this plethora of data there are very few books that assimilate the literature to provide a comprehensive, readable and contemporary overview of their management. This book aims to meet these requirements covering both sporadic and neurofibromatosis type 2 vestibular schwannomas.
The chapters within the book will cover all aspects of the diagnosis and management of vestibular schwannomas. Opening chapters provide a historical back drop, followed by current state of the art of molecular biology, histopathology and genomics relating to vestibular schwannomas. A comprehensive section related to the assessment of patients with vestibular schwannomas will highlight the multidisciplinary approach to the management of these tumors. This will set out some of the cutting edge research currently being undertaken in prediction of tumor growth using novel biological and radiological markers. The next section focuses on the treatment of vestibular schwannomas. This will make up the largest proportion of the book and will cover all treatment modalities from observation through to stereotactic radiosurgery and microsurgical resection. Lastly will be a section focusing on rehabilitation of neurological deficit arising as a result of the disease or its treatment.
- Consolidates best practice on diagnosis and treatment of vestibular schwannomas
- Includes both sporadic and neurofibromatosis type 2 vestibular schwannomas
- Covers stereotaxic radiosurgery and microsurgical resection
- Discusses molecular biology, histopathology and genomics
- Presents rehabilitation for neurological deficits resulting from schwannomas and treatment
Clinical neurologists
Introduction
1.History of VS management
Basic Science
2, Anatomy and histopathology of vestibular schwannomas
3.Molecular biology and disease models of vestibular schwannomas: State of the art
4. Vestibular schwannoma micro-environment
5. Genomics of vestibular schwannoma
Assessment
6. Clinical evaluation of patients with a VS
7. Radiology and Differential diagnosis of cerebellopontine angle tumours
8. The MDT approach to managing VS
9. Natural history and epidemiology of vestibular schwannomas
Treatment
10. Watch wait and rescan for vestibular schwannomas
11. Medical therapy for vestibular schwannomas
12. Translab approach to vestibular schwannomas
13. Retrosigmoid approach to vestibular schwannomas
14. Middle fossa approach to vestibular schwannomas
15. Outcomes of rescue surgery following failed primary treatment
16. Vestibular Schwannoma Microsurgical Technique
17. Outcomes following VS surgery
18. Hearing preservation surgery
19. How to deal with complications following VS surgery
20. Neuroanaesthesia and peri-operative care of vestibular schwannoma surgery
Stereotactic radiosurgery for vestibular schwannomas
21. Radiobiology of radiotherapy treatments in vestibular schwannoma
22. Radiotherapy modalities in vestibular schwannoma treatment
23. Outcomes and complications of radiotherapy in vestibular schwannomas
General Considerations
24. Decision making in sporadic VS
25. Decision making in NF2
26. Quality of life after treatment of vestibular schwannomas
27. The role of the specialist nurse in skull base disease
28. Managing vestibular schwannoma in the developing world
Rehabilitation
29. Managing trigeminal neuralgia in VS
30. Hearing rehab in patients with a VS
31. Rehabilitation of facial palsy in patients with vestibular schwannoma
32. Managing dizziness in patients with vestibular schwannomas
33. Managing tinnitus in patients with vestibular scwhannomas
- No. of pages: 500
- Language: English
- Edition: 1
- Volume: TBD
- Published: June 1, 2026
- Imprint: Elsevier
- Hardback ISBN: 9780128245347
- eBook ISBN: 9780323859974
SL
Simon Lloyd
Professor Lloyd is a Consultant Skull Base and Auditory Implant Surgeon at the Manchester Royal Infirmary, Royal Manchester Children’s Hospital and Salford Royal Hospital. He is Professor of Otology and Skull Base Surgery at the University of Manchester and his research interests include the natural history of vestibular schwannomas and neurofibromatosis type 2. He is widely published in his field and is frequently invited to speak both nationally and internationally. He holds a number of high profile positions including secretary to the British Society of Otology and secretary to the British Skull Base Society. He sits on the Royal Society of Medicine Otology section council and is a member of the European Academy of Otology and Neuro-Otology and the Politzer Society. He has recently been awarded the Dalby Prize by the Royal Society of Medicine. This prize recognises the individual that has made the greatest contribution to otological research over the last 5 years. He is also the director of the UKs leading advanced otology course and skull base course. He has been deputy editor of the Mediterranean Journal of Advanced Otology and is on the editorial board of Cochlear Implants International. He has published over 50 peer reviewed papers and 14 book chapters. He has also edited two books. He regularly reviews submissions to peer reviewed medical journals including the Lancet, Otology and Neurotology, Cochlear Implants International and Clinical Otolaryngology amongst others. He is an examiner for the Intercollegiate FRCS(ORL-HNS) examinations.
Affiliations and expertise
Dept Otolaryngology Head and Neck Surgery
Manchester Royal Infirmary
UKOP
Omar Pathmanaban
Dr Pathmanaban is a Consultant Neurosurgeon, whose special interest is in surgical and multi-modal management of diseases of the skull base. He is one of the UKs leading endoscopic skull base surgeons and is referred complex cases from across the UK and internationally. He trained in London, Manchester, Oxford, Toronto and he won the Marjorie Newsome visiting fellowship at the Barrow Neurological Institute, USA. Amongst his many awards, are the Norman Dott Gold Medal for the most outstanding performance amongst graduating Neurosurgeons in the UK and Ireland and 1st prize at the 12th European Skull Base Society Congress. He is the specialty training lead for the next generation of Neurosurgeons training in Manchester and is faculty on several advanced skull base training courses in the UK, as well as co-director of the Manchester Endoscopic Skull Base Surgery Course, which attracts surgeons from across the globe. He has a PhD in molecular and cellular Neuro-Oncology and is director of the Surgical Neuro-Oncology Manchester (SNO-Man) Laboratory, where he works as part of a team focused on translational tumour microenvironment research, including a programme of work on inflammatory biomarkers and therapeutic targets in vestibular Schwannoma. He sits on the Clinical Neurosciences Council of The Royal Society of Medicine and is on the panel of question writers for The Joint Committee on Intercollegiate Examinations in Neurosurgery.
Affiliations and expertise
Dept Neurosurgery
Manchester Ctr Clin Neurosci
Salford Royal Hospital
UKGE
Gareth Evans
Professor Evans is Professor of Medical Genetics at the University of Manchester. He is one of the world’s leading experts on breast cancer genetics and Neurofibromatosis type 2. He is an NIHR Senior Investigator and has published over 760 peer reviewed research publications; 276 as first or senior author. He has published over 126 reviews and chapters and has had a book published by Oxford University Press on familial cancer. He has an ISI web of knowledge H-index of 100 and a google scholar H-index of 139 having only published his first article in 1990. In the last 5 years he has raised over £35 million in grants for multicentre and local studies – approximately £31 million to Manchester. He is Chief Investigator on two (£1.59 & £1 million) NIHR program grant (2009-2014 and 2016-2020) on breast cancer risk prediction and also has an NIHR RfPB grant as CI (2011). He has led a successful bid for a Nationally funded NF2 service (£7.5 million pa) that started in 2010. He is theme lead and cancer lead on the All Manchester NIHR Biomedical Research Centre worth £28.5 Million (2016-2020). He also leads the NICE Familial Breast Cancer Guideline Development Group.
Affiliations and expertise
Professor of Medical Genetics, Academic Unit of Medical Genetics, St. Mary's Hospital, Manchester, UK.