Fundamentals of Brain Organoids for Neurological Diseases
- 1st Edition - October 10, 2025
- Latest edition
- Editors: Balachandar Vellingiri, Mahalaxmi Balachandar
- Language: English
Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological… Read more
Description
Description
Key features
Key features
- Presents the steps involved in the generation of brain organoids from HiPSCs onwards
- Summarizes the importance of organoids in understanding various neurodevelopmental disorders
- Reviews the ongoing clinical trials using brain organoids
- Discusses ethical considerations when conducting organoid research
Readership
Readership
Table of contents
Table of contents
1. An overview on organoids - Past, present and future scenario of organoids
Section II Neurodevelopmental disorder
2. A brief introduction about neurodevelopmental disorders
3. Use of brain organoids for autism
4. Role of brain organoids in Rett Syndrome
5. Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches
6. Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders
Section III Neurodegenerative diseases
7. An overview of neurodegenerative diseases
8. Use of brain organoids for Parkinson’s disease and Alzheimer’s disease
9. Application of brain organoids in Huntington’s disease
10. Ongoing clinical trials on use of brain organoids for neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc.)
Section IV Methods involved in organoids development
11. How human-induced pluripotent stem cells are derived into organoids
12. Elements required and days involved in organoid generation
Section V – Application and advancement of Brain organoids
13. Brain organoids – Challenges while constructing organoids
14. Existing drug targeting and research using brain organoids
Section VI - Ethical consideration while conducting organoids research
15. Ethical consideration while conducting organoids research
Section VII - Future perspective and concluding remarks
16. Future directions and conclusion
Product details
Product details
- Edition: 1
- Latest edition
- Published: October 20, 2025
- Language: English
About the editors
About the editors
BV
Balachandar Vellingiri
Dr. Balachandar Vellingiri currently is investigating various neurological diseases and developing human induced pluripotent stem cells (HiPSCs). Exploring the cutting-edge molecular, cellular, and translational neuroscience approaches, he aims to unravel disease mechanisms, identify therapeutic targets, and develop innovative interventions to slow or reverse neurological diseases. His expertise is on several techniques such as molecular cytogenetics, pathway analysis, and techniques in developing HiPSCs and Brain organoids, especially for neurological diseases.
MB
Mahalaxmi Balachandar
Dr. Mahalaxmi Balachandar is a researcher, currently involved in handling neurological disorder patients and conducting genetic and epigenetic studies. Her expertise is in handling bone marrow derived mesenchymal stem cells (BM-MSCs) as a promising therapeutic agent for LHON disease.