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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • Renal Disease in Cancer Patients

      • 1st Edition
      • September 2, 2013
      • Kevin W. Finkel + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 1 5 9 4 8 8
      • eBook
        9 7 8 0 1 2 3 9 8 2 5 3 7
      Renal Disease in Cancer Patients is a translational reference detailing the nephrological problems unique to patients with cancer in an organized and authoritative fashion. This book provides a common language for nephrologists, oncologists, hematologists, and other clinicians who treat cancer patients, to discuss the development of renal diseases in the context of cancer and options for their optimum diagnosis, management, and treatment. With the advent of better supportive care and the era of personalized medicine, patients with cancer are living longer, and oncologists and nephrologists now recognize the serious consequences of renal disease among these patients. Designed especially with this new need in mind, Renal Disease in Cancer Patients presents the various renal diseases affecting cancer patients in a single, authoritative volume. The book covers topics in radiation nephritis, obstructive nephropathy, drug nephropathy, graft-versus-host disease, and more.

    • Advances in Molecular Toxicology

      • 1st Edition
      • Volume 7
      • August 7, 2013
      • English
      • Hardback
        9 7 8 0 4 4 4 6 2 6 4 5 5
      • Paperback
        9 7 8 0 4 4 4 6 3 8 4 1 0
      • eBook
        9 7 8 0 4 4 4 6 2 6 5 5 4
      Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of progress on the molecular level and on advances in technological approaches employed.

    • Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics

      • 1st Edition
      • June 27, 2013
      • Lisa M. Plitnick + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 8 1 0 6
      • eBook
        9 7 8 0 1 2 3 9 4 8 2 3 6
      Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products. This book compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory documents. Each section discusses a different type of biologic, as well as early characterization strategies, principles of study design, preclinical pharmacokinetics and pharmacodynamics and preclinical assays. An edited book that is authored by leading experts in the field, this comprehensive reference provides critical insights to all researchers involved in early through late stage biologics.

    • Computational Toxicology

      • 1st Edition
      • June 4, 2013
      • Bruce A. Fowler
      • English
      • Hardback
        9 7 8 0 1 2 3 9 6 4 6 1 8
      • eBook
        9 7 8 0 1 2 3 9 6 5 0 8 0
      Computational Toxicology: Methods and Applications for Risk Assessment is an essential reference on the translation of computational toxicology data into information that can be used for more informed risk assessment decision-making. This book is authored by leading international investigators who have real-world experience in relating computational toxicology methods to risk assessment. Key topics of interest include QSAR modeling, chemical mixtures, applications to metabolomic and metabonomic data sets, toxicogenomic analyses, applications to REACH informational strategies and much more. The examples provided in this book are based on cutting-edge technologies and set out to stimulate the further development of this promising field to offer rapid, better and more cost-effective answers to major public health concerns.

    • Persistent Organic Pollutants and Toxic Metals in Foods

      • 1st Edition
      • May 15, 2013
      • Martin Rose + 1 more
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 2 4 5 8
      • eBook
        9 7 8 0 8 5 7 0 9 8 9 1 7
      Persistent organic pollutants (POPs) and toxic elements, such as dioxins, flame retardants, lead and mercury, are substances of major concern for the food industry, the regulator and the public. They persist in the environment, accumulate in food chains and may adversely affect human health if ingested over certain levels or with prolonged exposure. Persistent organic pollutants and toxic metals in foods explores the scientific and regulatory challenges of ensuring that our food is safe to eat.Part one provides an overview of regulatory efforts to screen, monitor and control persistent organic pollutants and heavy metals in foods and includes case studies detailing regulatory responses to food contamination incidents. Part two moves on to highlight particular POPs, toxic metals and metalloids in foods, including dioxins and polychlorinated biphenyls (PCBs), mercury, polycyclic aromatic hydrocarbons (PAHs) and phthalates.Persisten... organic pollutants and toxic metals in foods is a standard reference for those in the food industry responsible for food safety, laboratories testing for food chemical safety, regulatory authorities responsible for ensuring the safety of food, and researchers in industry and academia interested in the science supporting food chemical safety.

    • Haschek and Rousseaux's Handbook of Toxicologic Pathology

      • 3rd Edition
      • May 1, 2013
      • Brad Bolon + 4 more
      • English
      • Hardback
        9 7 8 0 1 2 4 1 5 7 5 9 0
      • eBook
        9 7 8 0 1 2 4 1 5 7 6 5 1
      Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more.

    • Drug-Induced Liver Disease

      • 3rd Edition
      • April 18, 2013
      • Neil Kaplowitz + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 8 7 8 1 7 5
      • eBook
        9 7 8 0 1 2 3 8 7 8 1 8 2
      This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the pharmaceutical industry and government settings. This book contains 4 new chapters on key topics in the area and provides a current and extensive review of the latest developments concerning the toxicology, pharmacology, genetics and immunology of drug-induced liver disease.

    • Nonclinical Study Contracting and Monitoring

      • 1st Edition
      • December 31, 2012
      • William F. Salminen + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 7 8 2 9 5
      • eBook
        9 7 8 0 1 2 3 9 7 8 3 1 8
      Nonclinical Study Contracting and Monitoring: A Practical Guide offers a systematic and straightforward handbook for obtaining high quality preclinical Good Laboratory Practice (GLP) studies. This book is full of real-world examples, processes, procedures, useful templates, checklists and sample reports to provide readers with a better understanding of exactly what happens during all stages of a GLP study and the critical aspects of GLP study design and conduct. Designed for both the novice and experienced scientist, this book covers the GLP regulations and how they impact preclinical studies, the differences between GLP, non-GLP and peer-reviewed studies, preclinical GLP study design, laboratory selection, contracts and business ethics, how to obtain test material for the study, animal sourcing and release for study, preparation of a draft report and much more. By illustrating the overall big picture and tying it together with the individual steps, this book is an essential resource to help scientists ensure a high quality GLP study that passes both scientific and regulatory scrutiny.

    • Agricultural and Industrial Applications Environmental Interactions

      • 1st Edition
      • December 2, 2012
      • Dewayne Torgeson
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 8 7 8
      • eBook
        9 7 8 0 3 2 3 1 4 3 0 2 8
      Fungicides, Volume I: Agricultural and Industrial Applications, Environmental Interactions discusses the application, use, and environmental interactions of fungicides. This book is organized into 15 chapters that cover the commercial development of fungicide and the organism's interaction with the environment. After discussing the history of fungicides, the book presents data on world fungicide usage and how this usage is influenced by epidemiology. It then describes procedures and approaches for commercial fungicide development; practical tests and laboratory techniques for agricultural fungicide toxicity; and significance of fungicide formulation that is determined by a variety of factors, including cost and biological efficiency. The following chapters discuss technological evolution, both in chemical fungicides and in the machinery for their application for soil and seed treatment. The application of foliar and postharvest fungicides and the use of other fungicides as industrial and wood preservatives is also tackled. The last four chapters are concerned with the various interactions between fungicides and the environment which may cause them to be more or less effective. The book will be useful to researchers, advanced students, and professional workers in the fungicide field of study who are concerned with the synthesis and development of better fungicides or their mode of action.

    • Pyrethrum

      • 1st Edition
      • December 2, 2012
      • John Casida
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 6 8 6 7
      • Hardback
        9 7 8 0 1 2 1 6 2 9 5 0 2
      • eBook
        9 7 8 0 3 2 3 1 5 4 9 0 1
      Pyrethrum: the Natural Insecticide covers the papers presented at the 1972 ""International Symposium on Recent Advances with Pyrethrum the Natural Insecticide"" held in conjunction with the American Institute of Biological Sciences Silver Anniversary Meeting at the University of Minnesota, Minneapolis. It deals with all aspects of pyrethrum, including its history, production, chemistry, biochemistry, toxicology, pharmacology, and agricultural applications. The introductory part addresses the early history of pyrethrum, its recognition as a modern insecticide, and its worldwide production. The chemistry and biochemistry parts discuss the composition, isolation, structure, synthesis, biosynthesis, metabolism, and action on enzyme systems of natural pyrethrins extracted from pyrethrum flower. The book also examines the toxicology of pyrethrum and its constituents to mammals, fish, and wildlife, as well as tests for possible teratogenic, carcinogenic, mutagenic, and allergenic activities. Finally, it discusses the domestic and agricultural applications of pyrethrum. Considering its desirable features, researchers find pyrethrum unsurpassed by any type of synthetic organic insecticide and even by the best synthetic analogs or pyrethroids.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation