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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

    • Advances in Molecular Toxicology

      • 1st Edition
      • Volume 7
      • August 7, 2013
      • English
      • Hardback
        9 7 8 0 4 4 4 6 2 6 4 5 5
      • Paperback
        9 7 8 0 4 4 4 6 3 8 4 1 0
      • eBook
        9 7 8 0 4 4 4 6 2 6 5 5 4
      Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of progress on the molecular level and on advances in technological approaches employed.
    • Annual Review of Chronopharmacology

      • 1st Edition
      • October 22, 2013
      • A. Reinberg + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 5 2 1 8
      • eBook
        9 7 8 1 4 8 3 1 9 1 0 2 7
      Annual Review of Chronopharmacology, Volume 2 presents a scholarly means of rapidly communicating findings and developments in chronopharmacology, which is considered a quickly emerging field. This text first discusses aspects and statistical procedures in chronobiology and chronopharmacology. This book then explains circadian and circannual changes in nephrotoxic effects of heavy metals and antibiotics; chronotoxicology and chronopharmacology with emphasis on carcinostatic agents; and chronopharmacology of cardiovascular medications. The chronopharmacology and chronotherapy of asthma are also tackled. This book concludes by explaining the chronopharmacology of antidepressant drugs and of the inflammatory process. This publication will be invaluable to those interested in the field of chronopharmacology.
    • Routes of Drug Administration

      • 1st Edition
      • October 22, 2013
      • A. T. Florence + 1 more
      • English
      • Paperback
        9 7 8 0 7 2 3 6 0 9 2 2 3
      • eBook
        9 7 8 1 4 8 3 1 8 3 6 1 9
      Routes of Drug Administration covers topics about parenteral and enteral routes of drug administration. The book discusses the anatomy and physiology of administration sites; the formulation and design of delivery systems; and other relevant aspects of biopharmaceutics. The text describes pulmonary delivery, nasal, buccal, and transdermal routes of administration for systemic delivery, as well as a number of systems for more localized therapy with antibiotics. Innovative methods of antibiotic administration, such as continuous and intermittent infusion, endotracheal installation, aerosol delivery, antibiotic-impregnat... catheters, antibiotic-containin... bone cement, and beads, are also considered. Senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences and practitioners in these fields, as well as other professionals concerned with the preparation and administration of medicines and the monitoring of drug therapy will find the book useful.
    • Biological Response Mediators and Modulators

      • 1st Edition
      • October 22, 2013
      • J. Thomas August
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 8 2 2
      • eBook
        9 7 8 1 4 8 3 2 1 6 2 5 6
      Biological Response Mediators and Modulators explains that the behavior of a cell depends upon the absorption of the ligand, the quantity of functional receptors existing for ligand recognition and binding, and the transduction of the signal through successive intercellular events. The book presents such model systems as the low-density lipoprotein (LDL) receptor, the epidermal growth factor receptor, and the insulin receptor. The LDL receptor is a model for a class of surface receptors that facilitate the cellular application of macromolecules through the process of receptor-mediated endocytosis. The book discusses the general characteristics of receptor-mediated endocytosis. Another topic of interest is the property of growth-related cell surface receptors. The section that follows describes the function of these receptors as tyrosine-specific protein kinases, which is related to the protein yields of some viral oncogenes. The amount of receptors in a cell depends upon the rates of synthesis and inactivation. The book will provide valuable insights for scientists, cytologists, students, and researchers in the field of chemistry.
    • Ions-Cyclic Nucleotides-Cholinergy

      • 1st Edition
      • October 22, 2013
      • J.C. Stoclet
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 2 7 6 7
      • eBook
        9 7 8 1 4 8 3 1 8 8 5 7 7
      Advances in Pharmacology and Therapeutics, Volume 3: Ions – Cyclic Nucleotides – Cholinergy covers the proceedings of the Seventh International Congress of Pharmacology, held in Paris in 1978. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into. This text presents in its latter part papers on chemical structure and cholinergic activity. This volume will be valuable to students and experts in the field of pharmacology, therapeutics, and related fields.
    • Experiments with Drugs

      • 1st Edition
      • October 22, 2013
      • H. J. Eysenck
      • English
      • Hardback
        9 7 8 1 4 8 3 1 9 8 7 1 2
      • Paperback
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      • eBook
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      Experiments With Drugs: Studies in the Relation between Personality, Learning Theory and Drug Action provides a report of a series of experiments, conducted to test the effects of certain groups of drugs, depressants and stimulants, on human behavior. The book presents a number of experiments, together with the theoretical rationale underlying their development. The text begins with a chapter that sets the stage for the exposition of the various concepts and findings on drug effects on behavior. Subsequent chapters deal with particular subjects such as personality and drug effects; the effects of stimulant and depressant drugs on visual and auditory masking; excitation-inhibitio... and the theory of neurosis; interaction effects of drugs; and the influence of stimulant and depressant drugs on the central nervous system. Psychologists, biochemists, and researchers in the field of psychopharmacology will find the book useful and incisive.
    • Current Concepts in Drug Metabolism and Toxicology

      • 1st Edition
      • Volume 63
      • June 12, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 8 3 3 9 8
      • Paperback
        9 7 8 0 3 2 3 2 8 2 2 1 5
      • eBook
        9 7 8 0 1 2 3 9 8 3 5 9 6
      This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
    • Handbook of Mutagenicity Test Procedures

      • 2nd Edition
      • December 2, 2012
      • B.J. Kilbey + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 7 1 9 2
      • eBook
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      The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.
    • Advances in Molecular Toxicology

      • 1st Edition
      • Volume 6
      • August 1, 2012
      • English
      • Paperback
        9 7 8 0 4 4 4 6 0 2 3 4 3
      • Hardback
        9 7 8 0 4 4 4 5 9 3 8 9 4
      • eBook
        9 7 8 0 4 4 4 5 9 4 0 2 0
      Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of both progress on the molecular level and on advances in technological approaches employed.
    • Agricultural and Industrial Applications Environmental Interactions

      • 1st Edition
      • December 2, 2012
      • Dewayne Torgeson
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 8 7 8
      • eBook
        9 7 8 0 3 2 3 1 4 3 0 2 8
      Fungicides, Volume I: Agricultural and Industrial Applications, Environmental Interactions discusses the application, use, and environmental interactions of fungicides. This book is organized into 15 chapters that cover the commercial development of fungicide and the organism's interaction with the environment. After discussing the history of fungicides, the book presents data on world fungicide usage and how this usage is influenced by epidemiology. It then describes procedures and approaches for commercial fungicide development; practical tests and laboratory techniques for agricultural fungicide toxicity; and significance of fungicide formulation that is determined by a variety of factors, including cost and biological efficiency. The following chapters discuss technological evolution, both in chemical fungicides and in the machinery for their application for soil and seed treatment. The application of foliar and postharvest fungicides and the use of other fungicides as industrial and wood preservatives is also tackled. The last four chapters are concerned with the various interactions between fungicides and the environment which may cause them to be more or less effective. The book will be useful to researchers, advanced students, and professional workers in the fungicide field of study who are concerned with the synthesis and development of better fungicides or their mode of action.