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Renal Disease in Cancer Patients
- 1st Edition - September 2, 2013
- Editors: Kevin W. Finkel, Scott C. Howard
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 4 1 5 9 4 8 - 8
- eBook ISBN:9 7 8 - 0 - 1 2 - 3 9 8 2 5 3 - 7
Renal Disease in Cancer Patients is a translational reference detailing the nephrological problems unique to patients with cancer in an organized and authoritative fashion.… Read more
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Request a sales quoteRenal Disease in Cancer Patients is a translational reference detailing the nephrological problems unique to patients with cancer in an organized and authoritative fashion. This book provides a common language for nephrologists, oncologists, hematologists, and other clinicians who treat cancer patients, to discuss the development of renal diseases in the context of cancer and options for their optimum diagnosis, management, and treatment.
With the advent of better supportive care and the era of personalized medicine, patients with cancer are living longer, and oncologists and nephrologists now recognize the serious consequences of renal disease among these patients. Designed especially with this new need in mind, Renal Disease in Cancer Patients presents the various renal diseases affecting cancer patients in a single, authoritative volume. The book covers topics in radiation nephritis, obstructive nephropathy, drug nephropathy, graft-versus-host disease, and more.
- Covers clinical description, diagnostics, management, and treatment throughout along with genetics, animal models, and pathology in specific chapters
- Summarizes all renal diseases unique to cancer patients in a single reference
- Provides a resource for oncologists and nephrologists, as well as general internal and family medicine practitioners, and physicians in training
Practicing clinicians, fellows, and residents in oncology, hematology, and nephrology
Dedication
Preface
Foreword
References
Acknowledgement
Contributors
Chapter 1. Introduction
References
Chapter 2. Acute Kidney Injury in Cancer Patients
Abstract
Introduction
Defining Acute Kidney Injury
Classification of Acute Kidney Injury
Conclusion
References
Chapter 3. Biomarkers in Oncology and Nephrology
Abstract
Acknowledgments
Introduction
Biomarkers in Oncology
Biomarkers in Nephrology
Summary
References
Chapter 4. Tumor Lysis Syndrome
Abstract
Acknowledgments
Introduction
Definition of Tumor Lysis Syndrome
Pathophysiology
Tumor Lysis Syndrome: One Syndrome or Several?
Epidemiology and Risk Factors
Risk Assessment
Grading of Tumor Lysis Syndrome Severity
Management
Sequelae of Tumor Lysis Syndrome
Prevention of Tumor Lysis Syndrome by Altering Initial Cancer Therapy
Summary
References
Chapter 5. Multiple Myeloma and Kidney Disease
Abstract
Introduction
Cast Nephropathy
Al Amyloidosis
LCDD
Bisphosphonates
Renal Transplant
References
Chapter 6. Kidney Disease in Patients Undergoing Hematopoietic Cell Transplantation
Abstract
Introduction
Current Practice of Hct
Evaluation of Kidney Disease During Hct
Acute Kidney Injury
Chronic Kidney Disease
Specific Kidney Diseases After Hct
Conclusion
References
Chapter 7. Radiation-associated Kidney Injury
Abstract
Introduction
Pathogenesis
Epidemiology
Modern Radiation and the Kidneys
Clinical Presentation
Diagnosis
Treatment
Prognosis
Summary
References
Chapter 8. Molecular-targeted Therapy for Renal Cell Carcinoma
Abstract
Introduction
Mechanisms of Action
Molecular-Targeted Drugs
Summary
References
Chapter 9. Renal Tumors in Children
Abstract
Renal Tumors in Children/Adolescents
Wilms Tumor
Non-Wilms Renal Tumors
Surveillance After Completion of Therapy
References
Chapter 10. Renal Effects of Leukemia and Lymphoma
Abstract
Introduction
Lymphoma
Cytotoxic Nephropathy/Hemophagocytic Syndrome
Leukemia
References
Chapter 11. Fluid and Electrolyte Abnormalities in Patients with Cancer
Abstract
Introduction
Sodium and Water
Hypoalbuminemia, Intravascular Volume Contraction and Hyponatremia
Clinical Outcomes in Cancer Patients with Hyponatremia
Potassium
Magnesium
Uric Acid
Phosphate
Calcium
Renal
Causes of Hypocalcemia
References
Chapter 12. Infections of the Kidney in Cancer Patients
Abstract
Introduction
Epidemiology
Bacterial Infections
Fungal Infections
Parasite Infections
Viral Infections
Summary
References
Chapter 13. Drug Nephropathies
Abstract
Introduction
Agents with Predominantly Tubular Toxicity
Agents With Predominantly Glomerular Toxicity
Agents Associated with Electrolyte Abnormalities
Conclusions
References
Chapter 14. Paraneoplastic Glomerulopathy
Abstract
General Features
Glomerular Lesions in Solid Tumors
The Hematologic Malignancies
Screening Recommendations for Paraneoplastic Glomerulonephritis
Management of Paraneoplastic Glomerulonephritis
References
Chapter 15. Pharmacokinetics of Anti-cancer Chemotherapy in Renal Insufficiency and Dialysis
Abstract
Introduction
Drug Properties that Influence Renal and Extracorporeal Elimination
Hemodialysis and Antineoplastic Agents
Cell Kinetic Theory of Chemotherapy
Classes of Antineoplastic Agents
Summary
References
Chapter 16. Cancer in Renal Transplant Patients
Abstract
Introduction
Incidence
Causes
Diagnosis and Treatment
Prevention
Conclusion
References
Index
Color Plates
- No. of pages: 312
- Language: English
- Edition: 1
- Published: September 2, 2013
- Imprint: Academic Press
- Hardback ISBN: 9780124159488
- eBook ISBN: 9780123982537
KF
Kevin W. Finkel
Affiliations and expertise
Professor and Clinical Vice-Chairman of Medicine; Director, Division of Renal Diseases & Hypertension; Chief, Section of Critical Care Nephrology, University of Texas Medical School, Houston, TX, USASH
Scott C. Howard
Affiliations and expertise
Associate Member, St. Jude Faculty, Medical Information Officer; Director of Clinical Trials, International Outreach Program, Division of Leukemia/Lymphoma, St. Jude’s Children’s Research Hospital, Memphis, TN, USARead Renal Disease in Cancer Patients on ScienceDirect