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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • Progress in Chemical Toxicology

      • 1st Edition
      • October 22, 2013
      • Abraham Stolman
      • English
      • Hardback
        9 7 8 0 1 2 5 3 6 5 0 5 5
      • Paperback
        9 7 8 1 4 8 3 2 0 5 8 1 6
      • eBook
        9 7 8 1 4 8 3 2 1 9 2 4 0
      Progress in Chemical Toxicology, Volume 5 covers topics on the improved isolation and detection procedures and quantitation methods for volatile poisons, stimulants, hallucinogenic drugs, and marihuana. The book discusses the absorption, distribution, and excretion of drugs and poisons and their metabolites; the system for the toxicological analysis of drugs in biological specimens; and the isolation and analysis of phenothiazines. The text also describes the use of fluorescence in toxicology and the toxicology of new synthetic organic polymers used in containers for food, pharmaceutical compounds, and drinkable water. Some microcrystal tests for drugs and advances in polarography as applied to toxicological analysis are also considered. Biochemists, toxicologists, and scientists involved in the study of narcotics will find the book invaluable.

    • Nitrogen and Phosphorus Solvents

      • 2nd Edition
      • Volume 2
      • October 22, 2013
      • D.R. Buhler + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 9 0 2 0 1
      This particular volume, Nitrogen and Phosphorus Solvents, is the second in a comprehensive and up-to-date series. The introduction of new nitrogen- and phosphorus- containing solvents used in industry has been accompanied by an explosion of knowledge about their properties, toxicity and metabolism. Even a relatively simple compound such as N-methylformamide undergoes a complex metabolic transformation in mammals. Such information, and other considerations contained in this volume will supply researchers and students with an excellent information source on modern mechanistic toxicology, while helping to provide a sound scientific basis for accurate health risk assessment.

    • Essays in Toxicology

      • 1st Edition
      • October 22, 2013
      • Wayland J. Hayes
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 0 1 0
      • eBook
        9 7 8 1 4 8 3 2 1 6 4 4 7
      Essays in Toxicology, Volume 4 covers three essays on habituating drugs, on the kinetics of the active-site-directed irreversible inhibition, and the hidden effects of trace elements. The first essay examines certain dependence-producing drugs; the mechanism of tolerance to barbiturates by changes in drugs metabolism; the distribution of barbiturates to the central nervous system; and the urinary excretion of barbiturates. The formation of morphine from heroin and codeine, and the dealkylation to form normorphine and to reduce naloxone to another compound is also considered in the first essay. The second essay discusses the time-course of enzyme inhibition at single-inhibitor concentrations and the effect of various inhibitor concentrations on the rate constants governing inhibition. The third essay is about the recondite toxicity of trace elements, taking into consideration the effects of these trace elements on body weight, survival, and longevity, clues to mechanisms of toxicity, and the production of chronic diseases simulating human disorders. Toxicologists, oncologists, biochemists, and pharmacologists will find the book invaluable.

    • Drugs and Driving

      • 1st Edition
      • October 22, 2013
      • Herbert Moskowitz
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 2 0 3 3
      • eBook
        9 7 8 1 4 8 3 1 8 7 8 4 6
      Drugs and Driving is a compendium of papers from a symposium of the same title presented at the U.S. Transportation Research Board. This collection reviews the effects of five classes of drugs on driving (amphetamines, tranquilizers, barbiturates, narcotics, cannabis), the other studies being made on drugs and driving, as well as some countermeasure programs against drunk driving. The papers report that amphetamines can induce risky driving behavior, tranquilizers can increase traffic accident risks, barbiturates can degrade driving skills especially when the drug is combined with alcohol, while marijuana use can impair important driving skills. Another paper evaluates drug use and driving risk among high school students in Toronto: results show that the total effect of infrequent use of drugs on accidents is small compared to alcohol use. A study of out-patients in Finland notes that the combined used of alcohol and drugs tend to increase accident frequency. One paper refutes that Alcohol Safety Action Programs in the United States are ineffective. This collection can be helpful for sociologist, psychologists, psychiatrists, traffic safety officers, and heads of urban safety and traffic divisions.

    • Physiology and Toxicology of Male Reproduction

      • 1st Edition
      • October 22, 2013
      • James C. Lamb + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 3 4 4 4 0 2
      • Paperback
        9 7 8 1 4 8 3 2 4 2 2 5 5
      • eBook
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      Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.

    • Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

      • 1st Edition
      • October 22, 2013
      • T.E. Gram
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 7 6 2 1
      Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.

    • Male Reproductive Toxicology

      • 1st Edition
      • October 22, 2013
      • Robert E. Chapin + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 2 9 7 2
      • Hardback
        9 7 8 0 1 2 4 6 1 2 0 7 5
      • eBook
        9 7 8 1 4 8 3 2 7 0 9 5 1
      Methods in Toxicology, Volume 3: Male Reproductive Toxicology, Part A, deals with the male reproductive system and discusses methods that will help identify toxicant-induced changes at all levels in living organisms. It is important to realize that a toxic effect does not occur in a vacuum. All work in toxicology must be predicated on a demonstrated adverse effect in vivo. If good toxicology cannot exist in a vacuum, then there must be a structure. Thus, the book begins by presenting a few models as examples of the ways experiments could be grouped to define the toxicity of a chemical. This is followed by separate chapters on methods such as male mouse sexual behavior test; in vitro techniques for assessing pituitary secretory function; histological methods for preservation of the rat testis; procedures for assessing testicular sperm head counts in mice, rats, and dogs; and guidelines for conducting rodent dominant lethal tests. Subsequent chapters cover topics such as methods for the isolation and purification of Leydig cells from rat and mouse testes, and techniques used in semen analysis and fertility assessment in the rabbit.

    • Handbook of Nanosafety

      • 1st Edition
      • December 17, 2013
      • Ulla Vogel + 5 more
      • English
      • Hardback
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      • Paperback
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      • eBook
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      Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment.

    • Insecticides

      • 1st Edition
      • October 22, 2013
      • Gunter Zweig
      • English
      • Hardback
        9 7 8 1 4 8 3 1 9 6 7 4 9
      • Paperback
        9 7 8 1 4 8 3 2 0 8 3 4 3
      • eBook
        9 7 8 1 4 8 3 2 2 1 7 7 9
      Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume II: Insecticides contains detailed analytical procedures for analysis of 47 widely used insecticides. This volume is composed of 47 chapters that cover the history, biological and chemical properties, and physical constants of these insecticides. Each chapter presents first the general information, followed by intensive discussion of the methods of occurrence and residue analysis of the insecticide. Methods of analysis covered in each chapter include chemical methods, gas-liquid chromatography, colorimetry, and enzymatic techniques. Each chapter also provides analysis of phosphorus and acetylcholinesterase inhibition of the insecticide, which is classified into two groups, namely, organochlorine and organophosphorus. Agriculturists, analytical chemists, and toxicologists will find this book rewarding.

    • Principles of Epidemiology

      • 1st Edition
      • October 22, 2013
      • Lewis H. Roht + 2 more
      • English
      • Spiral-bound
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      • eBook
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      Principles of Epidemiology: A Self-Teaching Guide consists of a series of problem-solving exercises designed to introduce and guide readers toward an understanding of the principles and methods of epidemiology, rather than the epidemiology of specific diseases or subject areas such as ""infectious disease"" or ""chronic disease"" epidemiology. The guide has been formulated to be used by itself or as a supplement to standard textbooks. It illustrates and illuminates the principles and concepts of epidemiology and provides the reader an opportunity to practice the application of these principles in a logical sequence. The guide is divided into 14 exercises. Each exercise will help readers to understand principles or methods used by epidemiologist. Topics covered include the patterns of disease, populations at risk and risk assessment, screening for disease, investigation of an epidemic, etiology of disease, principles of causation, study design in epidemiologic investigation, data interpretation, and the uses and applications of epidemiology.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation