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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • Preclinical Psychopharmacology

      • 1st Edition
      • January 22, 2016
      • D.G. Grahame-Smith
      • English
      • Hardback
        9 7 8 0 4 4 4 9 0 3 5 0 1
      • Paperback
        9 7 8 1 4 8 3 2 4 9 8 5 8
      • eBook
        9 7 8 1 4 8 3 2 7 5 3 3 8
      Psychopharmacology, Volume 2: Preclinical Psychopharmacology presents the mechanism of action of antidepressant drugs and neuroleptics. This book discusses the significance of the interaction between various neurotransmitter system in both biochemical and functional consequences of repeated drug administration. Organized into 12 chapters, this volume begins with an overview of the effects of antidepressant drugs on norepinephrine metabolism. This text then discusses the different aspects of monoamine oxidase and its inhibitors. Other chapters consider the mechanism of action of lithium, which requires consideration of some of the general characteristics of periodic behavior. This book discusses as well the preclinical aspects of tranquilizers, particularly those dealing with benzodiazepines and non-benzodiazepines acting through the benzodiazepine receptor. The final chapter deals with the various behavioral and electrophysiological effects of cocaine in animals, which presumably reflect both local anesthetic properties and action on monoamine mechanisms. This book is a valuable resource for neuropharmacologists and practicing psychiatrists.

    • Biochemical Immunological Pharmacology

      • 1st Edition
      • February 6, 2016
      • H. Yoshida + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 6 0 7 5
      • eBook
        9 7 8 1 4 8 3 1 4 8 4 9 6
      Advances in Pharmacology & Therapeutics II, Volume 4: Biochemical Immunological Pharmacology covers papers on the developments in pharmacology and therapeutics. The book contains invited lectures on the effect of drugs on immunological control mechanisms; the pharmacology of specific, pure and potent serotonin 5-HT2 or S2-antagonists; and the pharmacology of phospholipases A2 isolated from snake venoms. The text also contains papers on leukotrienes; the guanine nucleotide-binding regulatory component of adenylate cyclase; and the pharmacological and toxicological implications of multiple cytochromes P-450. The impact of the emerging biotechnologies on pharmacology; the action of antipsychotics on LSD-induced neurochemical and behavioral effects in rats; and the effect of histamine and related compounds on the immune response are also considered. The book also presents papers on inflammation; prostacyclin; prostaglandins; and chemical hazards to humans.

    • Genetic Toxicology Testing

      • 1st Edition
      • May 26, 2016
      • Ray Proudlock
      • English
      • Paperback
        9 7 8 0 1 2 8 0 0 7 6 4 8
      • eBook
        9 7 8 0 1 2 8 0 1 0 0 6 8
      Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own.

    • Abstracts

      • 1st Edition
      • April 19, 2016
      • J. R. Boissier + 2 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 5 7 2 5 2
      Abstracts contains the abstracts of work presented at the 7th International Congress of Pharmacology: invited lectures, symposia, methodological seminars, and free communications. The abstracts are organized in chronological order of presentation at the Congress. Some abstracts focus on chemistry and biochemistry of pituitary endorphins and their precursors; the biosynthesis and release of the enkephalins; enkephalin dynamics and neuronal localization; and physiological and pathophysiological relevance of the opiate receptors and their endogenous ligands. Other papers center on the mechanism of muscarinic receptor action; regulation of cholinergic receptor metabolism in skeletal muscle; the role of vitamin E in ozone-induced pulmonary toxicity; alcohol and electrophysiology of the central nervous system; and pharmacokinetic aspects of drug-alcohol interaction.

    • Atlas of Histology of the Juvenile Rat

      • 1st Edition
      • May 4, 2016
      • George A Parker + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 6 8 2 3
      • eBook
        9 7 8 0 1 2 8 0 2 6 9 6 0
      Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42.

    • The Evaluation of Toxicological Data for the Protection of Public Health

      • 1st Edition
      • July 29, 2016
      • W. J. Hunter + 1 more
      • English
      • Paperback
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      • eBook
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      The Evaluation of Toxicological Data for the Protection of Public Health: Proceedings of the International Colloquium, Luxembourg, December 1976 focuses on the review of toxicological tests and methods used in toxicological evaluation of chemicals and reconsideration of these procedures in identifying decision-making processes involved in the protection of public health. The selection first discusses reviews of toxicological tests, including introductory remarks and comments on acute toxicity; problems associated with the testing of environmental mutagens; and the testing of carcinogenic potentials. The publication also examines the uncertainties related to the evaluation of the health hazards of environmental chemicals from toxicological data and epidemiological monitoring of indices of chemical hazards. The book takes a look at safety factors and their application in toxicological evaluation; ecotoxicological approaches for the protection of environment and health; and use of biological materials as environmental pollution gauges. The text also discusses acute toxicity, teratogenic effects of pollutants, and examples of ecotoxicological research. The selection is a dependable source of data for readers interested in the evaluation of toxicological data relative to the protection of public health.

    • Pharmacology of Oriental Plants

      • 1st Edition
      • April 20, 2016
      • K. K. Chen + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 6 9 5 9 0
      • eBook
        9 7 8 1 4 8 3 1 8 5 4 0 8
      Pharmacology of Oriental Plants is a collection of papers that details the advancement in research of the pharmacological properties of oriental plants. The topics included in the text cover the chemical behavior and mode of action of plants. Several studies also tackle the medicinal properties of plants that undergo a specific process. The book will be of great use to pharmacologists, botanists, biochemists, horticulturists, and physicians. Advocates of natural and alternative medicine will also find the text interesting.

    • Alcohol, Drugs, Genes and the Clinical Laboratory

      • 1st Edition
      • October 17, 2016
      • Amitava Dasgupta
      • English
      • Paperback
        9 7 8 0 1 2 8 0 5 4 5 5 0
      • eBook
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      Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials.

    • Molecular Biological Markers for Toxicology and Risk Assessment

      • 1st Edition
      • June 8, 2016
      • Bruce A. Fowler
      • English
      • Hardback
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      • Paperback
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      • eBook
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      Molecular Biological Markers for Toxicology and Risk Assessment provides an introduction to the exciting field of biomarkers and their use in toxicology and risk assessment. In recent years, new classes of molecular biomarkers capable of detecting early manifestations of ongoing chemical-induced cell injury and cell death have been developed as a result of advances in analytical chemistry, molecular biology, and computational modeling. The interplay between these emergent tools of science has resulted in new insights into initial mechanisms of chemical-induced toxicity and carcinogenicity. Molecular Biological Markers for Toxicology and Risk Assessment guides the reader through a broad range of molecular biological markers, including the "omic" biomarkers, and provides an examination of the various elements in the evolution of these modern tools. It then explores possible ways in which these markers may be applied to advance the field of chemical risk assessment. Since molecular biomarkers and related technologies are inherently complex, the book concludes with a section on risk communication in order that readers may appreciate both the strengths and limitations of molecular biological marker approaches to risk assessment practice.

    • Basic Pharmacology

      • 3rd Edition
      • May 11, 2015
      • R W Foster
      • English
      • eBook
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      Basic Pharmacology, Third Edition aims to present accounts of drug actions and their mechanisms in a compact, inexpensive, and updated form, and explain the basis of the therapeutic exploitation of drugs. This book is divided into sections that follow a particular theme and is introduced by the relevant pharmacological general principles. In each section, the major groups of drugs related to the theme are discussed with detailed expositions of the important “type” substances. Drugs of lesser importance are placed in proper context. A list of abbreviations that are referenced throughout the book is provided after the introduction. An index is also included at the end. This edition is designed to help students taking pharmacology, including medical students of subjects affiliated to medicine, to appreciate the rationale underlying the uses of drugs in therapeutics.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation