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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • How Synthetic Drugs Work

      • 1st Edition
      • September 6, 2022
      • Imran Kazmi + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 8 5 5 0
      • eBook
        9 7 8 0 3 2 3 9 1 3 6 8 3
      How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs.

    • Tailor-Made Polysaccharides in Drug Delivery

      • 1st Edition
      • September 2, 2022
      • Amit Kumar Nayak + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 2 8 6 8
      • eBook
        9 7 8 0 1 2 8 2 1 2 8 7 5
      Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.

    • A Pharmacology Primer

      • 6th Edition
      • August 14, 2022
      • Terry P. Kenakin
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 2 8 9 3
      • eBook
        9 7 8 0 3 2 3 9 9 2 9 0 9
      A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. With full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics.

    • Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary

      • 1st Edition
      • Volume 95
      • August 9, 2022
      • English
      • Hardback
        9 7 8 0 3 2 3 9 1 1 0 9 2
      • eBook
        9 7 8 0 3 2 3 9 1 1 1 0 8
      Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary, Volume 95 highlights the extensive contributions by worldwide researchers in the cytochrome P450 (P450) field over the past six decades, and since the first article on P450 was published in 1962. Chapters in this new release include Multiple conformations of cytochromes P450 and the relevance to predicting SAR, Pharmacogenetics of the cytochromes P450 and relevance to drug metabolism, Cytochromes P450 drug metabolism within the brain, Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of woodrats with different dietary preferences, and more. Additional section cover Atypical kinetics of cytochrome P450 enzymes in drug metabolism, Biosynthesis using cytochrome P450 Enzymes: focus on synthesis of drug metabolites, Use of engineered cytochrome P450s for accelerating drug discovery and development, Assessing cytochrome P450 function using genetically engineered mouse models, Use of the biologicals with sustainable reproducibility for phenotyping study of cytochrome P450 enzymes involved in the biotransformation of test compounds and calculating the fraction unbound parameter, for anticipating drug Interactions, and much more. Research on many forms of P450s has been extended into different fields, from molecules to in vivo situations because pharmacologists and toxicologists appreciate and are attracted to the potential therapeutics. The purpose of this volume is to collect a comprehensive description of major progress to date, to discuss possible future directions, and to invite young researchers to join this important and exciting world of P450.

    • Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

      • 1st Edition
      • July 25, 2022
      • Sunny Ohia + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 2 9 1 7
      • eBook
        9 7 8 0 1 2 8 1 9 2 9 2 4
      Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-adminis... drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.

    • Applications of Nanovesicular Drug Delivery

      • 1st Edition
      • July 22, 2022
      • Amit Kumar Nayak + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 8 6 5 7
      • eBook
        9 7 8 0 3 2 3 9 1 9 5 3 1
      Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles. This volume will discuss target-specific drug application, such as ocular, transdermal, nasal, intravenous and oral delivery. This title is a valuable resource for academics, pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailored-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

    • Systems of Nanovesicular Drug Delivery

      • 1st Edition
      • July 16, 2022
      • Amit Kumar Nayak + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 8 6 4 0
      • eBook
        9 7 8 0 3 2 3 9 1 4 2 2 2
      Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles. This volume discusses cubosomes, proniosomes and niosomes, dendrimerosomes and other new and effective approaches for drug delivery. It will be a valuable title and resource for academics and pharmaceutical scientists, including industrial pharmacists, analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailor-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

    • Allgemeine und spezielle Pharmakologie und Toxikologie

      • 13th Edition
      • July 7, 2022
      • Klaus Aktories + 3 more
      • German
      • Hardback
        9 7 8 3 4 3 7 4 2 6 2 2 3
      • eBook
        9 7 8 3 4 3 7 0 5 8 1 2 7
      Wer mit „Aktories" lernt, versteht Das Standardwerk der Pharmakologie und Toxikologie in überarbeiteter 13. Auflage: das gesamte Wissen auf über 1.000 Seiten. Bewährt als erstklassiges Lehrbuch für Medizin- und Pharmaziestudierende... begehrt als Nachschlagewerk für Medizinier*innen und Pharmakolog*innen. Das gesamte Wissen der Pharmakologie und Toxikologie wird Ihnen hier verständlich und anschaulich erklärt und bringt Ihnen Sichherheit beim Lernen: Arzneimittelwirkunge... im Gesamtzusammenhang begreifen: Wirkmechanismen und pathophysiologische Bezüge in jedem Kapitel Zusammenhänge verstehen: Ausführliches Kapitel zur allgemeinen Pharmakologie und Toxikologie erleichtert Ihnen das Verständnis der speziellen pharmakologischen Zusammenhänge Praktische Relevanz: Empfehlungen zu Therapie und Dosierungen finden Sie in farbig hervorgehobenen Kästen Neu in der 13. Auflage: Hoch aktuelle Darstellung der Biologika (= das Gebiet der Pharmakologie, das am schnellsten wächst): signifikante Neuentwicklungen für die Tumortherapie, der Therapie rheumatischer Erkrankungen und anderer Autoimmunerkrankunge... der Therapie allergischer Erkrankungen und der Therapie der Psoriasis (Schuppenflechte) Bemerkenswerte Erkenntnisse bei der Einführung der SGLT-2-Inhibitoren (Sodium-Glucose-Like... 2) in der Diabetes-Typ2-Therap... Darstellung der vielfältigen Zusammenhänge von molekular-pharmakolo... Wirkungen der Arzneimittel und ihrer therapeutischen Anwendung (inklusive der mRNA-Technologie) Neue Arzneimittelentwickl... Ergänzung der IMPP-Arzneistofflist... (Markierung im Fließtext + eigenes Register)

    • Brenner and Stevens’ Pharmacology

      • 6th Edition
      • June 27, 2022
      • Craig W. Stevens
      • English
      • Paperback
        9 7 8 0 3 2 3 7 5 8 9 8 7
      More detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens’ Pharmacology, 6th Edition, focuses on the essential principles you need to know in a concise, easy-to-understand manner. Authored by Craig W. Stevens, PhD, this highly illustrated introductory text helps you learn and retain key information in pharmacology—taking you from course exams and the USMLE Step 1 right through to clinical practice. New and extensively revised content keeps you up to date with the latest pharmacologic mechanisms and applications.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 61
      • June 17, 2022
      • David R. Witty + 1 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 8 9 0 3 9
      • eBook
        9 7 8 0 3 2 3 9 8 9 0 4 6
      Progress in Medicinal Chemistry, Volume 61 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.

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