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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Astrocytes

    Pharmacology and Function
    • 1st Edition
    • December 2, 2012
    • Bozzano G Luisa
    • English
    Interest in the functional roles of astrocytes in the nervous system has grown significantly as it is recognized that these cells not only have their own pharmacology but also release neuro- and vaso-active factors. This book relates astrocyte pharmacology to cell function for the first time, making it an attractive text across the neuroscience community.

  • Adenosine in the Nervous System

    • 1st Edition
    • December 2, 2012
    • Richard E. Stone
    • English
    This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacol... and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.

  • Origins of Resistance to Toxic Agents

    • 1st Edition
    • December 2, 2012
    • M Sevag
    • English
    Origins of Resistance to Toxic Agents contains the proceedings of the Symposium held in Washington, D.C. on March 25-27, 1954. Contributors theoretically explore the origins of drug resistance and related problems, based on the concept that the development of resistance to various toxic agents is associated with alterations and/or loss in enzyme proteins, and can explain the mutational and other processes. This text is organized into five sections encompassing 25 chapters and begins with an overview of the evolutionary aspects of resistance to antibacterial agents, herbicides, and insecticides. The book then discusses spontaneous and induced mutations to drug resistance in Escherichia coli, along with the mechanism of drug resistance in protozoa and bacteria, the physiological aspects of insect resistance to insecticides, and the enzymatic detoxication of DDT. The next chapters focus on the origins of tolerance and addiction to drugs and the problem of alcoholism; biochemical effects of narcotics and alcohol administration; tolerance and physical dependence to narcotics; and resistance and dependence in cancer cells. The book concludes by analyzing the significance of protein configuration to the specificity of biological interaction. This book is a valuable source of information for physicians, biochemists, pharmacologists, entomologists, plant physiologists, students of cancer, and those who are interested in the theory of the evolution of living matter.

  • Spontaneous Animal Models of Human Disease

    • 1st Edition
    • Volume 2
    • December 2, 2012
    • Edwin J. Andrews + 2 more
    • English
    This two-volume work gathers together the diverse information presently available on spontaneous animal models of human disease. In addition to providing a comprehensive review of existing models, the book presents many previous unpublished new models.The scope of this work is limited to spontaneous models. Neoplasia, infectious diseases including parasitism, and nutritionally induced or other types of experimental models have not been included. The sixteen parts of the book are alphabetically arranged according to organ system with over 230 authors contributing to the overall effort. In addition to many illustrations, the book features an extensive bibliography.

  • T-Lymphocyte and Inflammatory Cell Research in Asthma

    • 1st Edition
    • December 2, 2012
    • G. Jolles + 2 more
    • English
    It is well established that asthma is an inflammatory disease of the airway mucosa and drugs like inhaled glucocorticoids are now commonly introduced early in therapy. A characteristic feature of this disease is the vast number of eosinophils in airway tissue, although many other migratory and resident inflammatory cells with the capacity to synthesize and release cytokines and putative asthma mediators are present in the inflamed mucosa. The cross-talk between lymphocytes and these cells and the role of cytokines in complex biological networks are currently areas of intense research.This volume gathers together chapters and discussions on the biology of immunocompetent and inflammatory cells, cellular interplay and communication, and on the relative importance of cells and mediators in disease.It should help contribute to further insights into the pathology of asthma and to the development of novel efficacious drugs for the treatment of asthma and related respiratory disorders.

  • Transforming Your STEM Career Through Leadership and Innovation

    Inspiration and Strategies for Women
    • 1st Edition
    • November 2, 2012
    • Pamela McCauley Bush
    • English
    Transforming Your STEM Career Through Leadership and Innovation offers valuable information on what it means to be a leader and innovator and encourages you to discover and develop these skills for yourself. This book integrates leadership and innovation principles with personal examples and profiles of inspirational women. By providing a clear process on how to build upon your personal strengths to realize leadership and innovation goals, this book will inspire you to pick up the mantle and meet the critical need for leadership and innovation in the STEM fields. This is a must-have guide that is relevant and valuable for women in all stages of their careers.

  • Lead Compounds from Medicinal Plants for the Treatment of Cancer

    • 1st Edition
    • October 22, 2012
    • Christophe Wiart
    • English
    Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today’s most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development.

  • Current Challenges in Personalized Cancer Medicine

    • 1st Edition
    • Volume 65
    • September 26, 2012
    • English
    For this volume of Advances in Pharmacology we have brought together some of the foremost basic science and clinical researchers to discuss some of the new frontiers in the development of targeted cancer therapy. Although still in its formative stages, the development of targeted cancer therapies has already shown incredible promise in a limited number of cancer types. As basic cancer research and drug development continues, we expect this number to grow and more patients to benefit from these exciting advances. Through better patient selection and novel strategies to manage resistance, a future can be envisaged in which cancer can be reduced to the level of a chronic, manageable disease.

  • Principles of Clinical Pharmacology

    • 3rd Edition
    • September 18, 2012
    • Shiew-Mei Huang + 2 more
    • English
    Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics

  • Practical Biostatistics

    A Friendly Step-by-Step Approach for Evidence-based Medicine
    • 1st Edition
    • July 26, 2012
    • Mendel Suchmacher + 1 more
    • English
    Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials.

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