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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

    • Protein Kinase Inhibitors in Research and Medicine

      • 1st Edition
      • Volume 548
      • July 1, 2013
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 9 1 8 6
      • eBook
        9 7 8 0 1 2 3 9 8 4 6 2 3
      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad kinome profiling of kinase inhibitors, and designing drug-resistant kinase alleles.
    • Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

      • 1st Edition
      • May 24, 2013
      • Mahendra Rai + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 8 5 3 9 2
      • eBook
        9 7 8 0 1 2 4 0 1 7 0 8 5
      Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery
    • Immunopharmacology

      • 1st Edition
      • Volume 66
      • February 18, 2013
      • David J Webb
      • English
      • Hardback
        9 7 8 0 1 2 4 0 4 7 1 7 4
      • Paperback
        9 7 8 0 3 2 3 2 8 2 8 0 2
      • eBook
        9 7 8 0 1 2 4 0 5 1 8 4 3
      This new volume of Advances in Pharmacology explores the current state of Alzheimer's disease research and therapeutics. Chapters cover such topics as the B cell targeted therapies, Lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
    • Pharmacogenomics

      • 1st Edition
      • February 12, 2013
      • Yui-Wing Francis Lam + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 1 9 1 8 2
      • eBook
        9 7 8 0 1 2 3 9 8 3 0 3 9
      Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference.
    • Drug Stability for Pharmaceutical Scientists

      • 1st Edition
      • January 30, 2013
      • Thorsteinn Loftsson
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 5 4 8 4
      • eBook
        9 7 8 0 1 2 4 1 1 5 6 2 0
      Drug Stability for Pharmaceutical Scientists is a clear and easy-to-follow guide on drug degradation in pharmaceutical formulation. This book features valuable content on both aqueous and solid drug solutions, the stability of proteins and peptides, acid-base catalyzed and solvent catalyzed reactions, how drug formulation can influence drug stability, the influence of external factors on reaction rates and much more. Full of examples of real-life formulation problems and step-by-step calculations, this book is the ideal resource for graduate students, as well as scientists in the pharmaceutical and related industries.
    • Nutritional Management of Renal Disease

      • 3rd Edition
      • December 17, 2012
      • Joel D. Kopple + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 1 9 3 4 2
      • eBook
        9 7 8 0 1 2 3 9 1 9 3 5 9
      This translational text offers in-depth reviews of the metabolic and nutritional disorders that are prevalent in patients with renal disease. Chapter topics address the growing epidemic of obesity and metabolic syndrome. Each chapter integrates basic and clinical approaches, from cell biology and genetics to diagnosis, patient management and treatment. Chapters in sections 4-7 include new illustrative case reports, and all chapters emphasize key concepts with chapter-ending summaries. New features also include the latest National Kidney Foundation Clinical Practice Guidelines on Nutrition in Chronic Renal Failure, the most recent scientific discoveries and the latest techniques for assessing nutritional status in renal disease, and literature reviews on patients who receive continuous veno-venous hemofiltration with or without dialysis.
    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 34
      • December 14, 2012
      • Jeffrey K Aronson
      • English
      • Hardback
        9 7 8 0 4 4 4 5 9 4 9 9 0
      • eBook
        9 7 8 0 4 4 4 5 9 5 0 3 4
      The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions. An international team of specialists has contributed to the informative Annual by critically interpreting it and by pointing to whatever is misleading.
    • Clinical Pharmacology During Pregnancy

      • 1st Edition
      • December 5, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 0 0 7 1
      • eBook
        9 7 8 0 1 2 3 8 6 0 0 8 8
      Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are covered, as are research issues, including clinical trial design and ethical considerations.
    • Biogenesis of Antibiotic Substances

      • 1st Edition
      • December 2, 2012
      • Zdenko Vanek
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 2 7 5 1
      • eBook
        9 7 8 0 3 2 3 1 5 5 8 3 0
      Biogenesis of Antibiotic Substances covers the proceedings of a panel discussion on ""Basic Research and Practical Aspects of Antibiotic Production"" held during the Antibiotic Congress in Prague. This book is organized into 25 chapters that cover the regulating mechanisms of primary antibiotic metabolite biosynthesis. This text describes the relationship between secondary metabolite production and synthesis of cell matter or cell wall. The opening chapters describe the parasexual cycle and some of the ways in which the cycle may be used for strain improvement, as well as the applications of refined techniques of genetic recombination and the principles of biochemical genetics to the field of antibiotics. The next chapter deals with cultural and fermentative characteristics of A-type isolates obtained from progenitor and representative member strains of the Wisconsin Family of Strains of Penicillium chrysogenum. Considerable chapters are devoted to the metabolite biosynthesis, such as geodoxin and related compounds; secondary metabolism of penicillins, gibberellins, and griseofulvin in fungi; and tetracycline metabolites. The book goes on examining the stereochemical aspects of macrolide antibiotics. It also describes the biosynthetic pathways involving ring cleavage of carbocyclic compounds, as well as the biosynthesis of different peptide antibiotics and of actinomycins and its relationship to protein synthesis. The production of phenazines is also explained. Other chapters consider other metabolites, such as those that decarboxylate, the malonate, and the 3-nitropropionic acid. A discussion on the role of carbohydrates and phosphate in the biosynthesis of different types of antibiotics is included. Lastly, microbiological assay procedures for antibiotic research and influencing factors are presented.
    • Spontaneous Animal Models of Human Disease

      • 1st Edition
      • Volume 2
      • December 2, 2012
      • Edwin J. Andrews + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 9 2 7 0
      • eBook
        9 7 8 0 3 2 3 1 3 8 2 8 4
      This two-volume work gathers together the diverse information presently available on spontaneous animal models of human disease. In addition to providing a comprehensive review of existing models, the book presents many previous unpublished new models.The scope of this work is limited to spontaneous models. Neoplasia, infectious diseases including parasitism, and nutritionally induced or other types of experimental models have not been included. The sixteen parts of the book are alphabetically arranged according to organ system with over 230 authors contributing to the overall effort. In addition to many illustrations, the book features an extensive bibliography.