Skip to main content
Elsevier
View Cart
My account

Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

BooksJournals

    • Therapeutic Protein Drug Products

      • 1st Edition
      • January 2, 2012
      • Brian K Meyer
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 1 8 3
      • Paperback
        9 7 8 0 0 8 1 0 1 6 5 8 9
      • eBook
        9 7 8 1 9 0 8 8 1 8 1 0 2
      Therapeutic protein drug products provides a comprehensive overview of therapeutic protein drug products, with an emphasis on formulation beginning in the laboratory, followed by manufacturing and administration in the clinic. A list of many commercial therapeutic drug products are described and include the product name, dosages, active concentration, buffer, excipients, Ph, container type and route of administration. The laboratory formulation sections focus on the most common buffers, excipients, and Ph ranges that are commonly tested in addition to systematic approaches. A brief section on biophysical and analytical analysis is also provided. Properties of therapeutic protein formulations are described and include opalescence, phase separation, color, and subvisible particles. An emphasis is placed on material and process testing to ensure success during manufacturing. The drug product manufacturing process, which includes the process of compounding to filling, is also covered. Methods of delivery in the clinic are addressed, as well as delivery strategies. Finally, a perspective on the regulatory requirements for therapeutic protein formulations is discussed.

    • Actinomycetes in Biotechnology

      • 1st Edition
      • December 2, 2012
      • Bozzano G Luisa
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 1 2 4 9
      • eBook
        9 7 8 0 0 8 0 9 8 4 3 3 9
      The actinomycetes are a group of bacteria well known as producers of antibiotics. With the advent of molecular biology they have become important to biotechnologists in the search for new antibiotics, vitamins, enzyme inhibitors, etc. They also play an important role in the biodegradation of wastes, and their wide (natural) distribution in soil, composts, water and elsewhere in the environment makes them important to the agricultural and waste industries. This research book presents a broad view of the current interest in actinomycetes, ranging from isolation/screening of actinomycetes, discovery of new antibiotics, a substantial contribution on genetic manipulation to actinomycetes in agriculture, forestry, and the threat of actinomycetes as pollutants in the environment.The chapters, which have been written by experts, are intended to provide a balanced view of the opportunities and problems in an expanding field of interest.

    • A Comprehensive Guide to Toxicology in Preclinical Drug Development

      • 1st Edition
      • October 18, 2012
      • Ali S. Faqi
      • English
      • Hardback
        9 7 8 0 1 2 3 8 7 8 1 5 1
      • Paperback
        9 7 8 0 1 2 8 1 0 0 5 3 0
      • eBook
        9 7 8 0 1 2 3 8 7 8 1 6 8
      A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing.

    • Lead Compounds from Medicinal Plants for the Treatment of Cancer

      • 1st Edition
      • October 22, 2012
      • Christophe Wiart
      • English
      • Hardback
        9 7 8 0 1 2 3 9 8 3 7 1 8
      • eBook
        9 7 8 0 1 2 3 9 8 3 8 2 4
      Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today’s most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development.

    • Nonclinical Study Contracting and Monitoring

      • 1st Edition
      • December 31, 2012
      • William F. Salminen + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 7 8 2 9 5
      • eBook
        9 7 8 0 1 2 3 9 7 8 3 1 8
      Nonclinical Study Contracting and Monitoring: A Practical Guide offers a systematic and straightforward handbook for obtaining high quality preclinical Good Laboratory Practice (GLP) studies. This book is full of real-world examples, processes, procedures, useful templates, checklists and sample reports to provide readers with a better understanding of exactly what happens during all stages of a GLP study and the critical aspects of GLP study design and conduct. Designed for both the novice and experienced scientist, this book covers the GLP regulations and how they impact preclinical studies, the differences between GLP, non-GLP and peer-reviewed studies, preclinical GLP study design, laboratory selection, contracts and business ethics, how to obtain test material for the study, animal sourcing and release for study, preparation of a draft report and much more. By illustrating the overall big picture and tying it together with the individual steps, this book is an essential resource to help scientists ensure a high quality GLP study that passes both scientific and regulatory scrutiny.

    • Profiles of Drug Substances, Excipients and Related Methodology

      • 1st Edition
      • Volume 36
      • June 16, 2011
      • Harry G. Brittain
      • English
      • Hardback
        9 7 8 0 1 2 3 8 7 6 6 7 6
      • Paperback
        9 7 8 0 3 2 3 1 6 4 4 4 3
      • eBook
        9 7 8 0 1 2 3 8 7 7 0 2 4
      Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

    • The Brain as a Drug Target

      • 1st Edition
      • Volume 98
      • January 12, 2011
      • Shafiqur Rahman
      • English
      • Hardback
        9 7 8 0 1 2 3 8 5 5 0 6 0
      • eBook
        9 7 8 0 1 2 3 8 5 5 0 7 7
      The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.

    • Pharmacy Management Software for Pharmacy Technicians: A Worktext

      • 2nd Edition
      • September 16, 2011
      • DAA Enterprises, Inc.
      • English
      • eBook
        9 7 8 0 3 2 3 5 8 4 2 3 4
      • eBook
        9 7 8 0 3 2 3 2 6 3 4 6 7
      Gain a head start on your career as a pharmacy technician with Pharmacy Management Software for Pharmacy Technicians, 2nd Edition. This innovative software/worktext package incorporates the full version of real pharmacy management software to give you hands-on training performing the day-to-day tasks of a pharmacy technician just as you will on the job. Easy-to-follow, step-by-step instructions guide you through entering patient data, prescription/medicat... orders, and insurance information, reviewing inventory, and more, enabling you to acquire the skills and experience for professional success before you leave the classroom!

    • Practical Leadership for Biopharmaceutical Executives

      • 1st Edition
      • May 5, 2011
      • Jane Y Chin
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 0 6 0
      • Paperback
        9 7 8 0 0 8 1 0 1 7 3 3 3
      • eBook
        9 7 8 1 9 0 8 8 1 8 0 2 7
      The biohealthcare executive in upper-middle management confronts leadership challenges unique to their industry: they manage highly specialized knowledge workers and innovators, compete at the speed of technology, work in a highly regulated environment where "free speech" often does not apply due to patient safety and privacy concerns, and increasingly are leading virtual teams who may be located in different parts of the world. Practical leadership for biopharmaceutical executives is a guide that strips away the theory and meets head-on the practical leadership challenges these executives face on a daily basis, and provides these "innovator leaders" with the tools to lead effectively in the face of technological complexity.

    • An Introduction to Pharmaceutical Sciences

      • 1st Edition
      • July 25, 2011
      • Jiben Roy
      • English
      • Paperback
        9 7 8 1 9 0 7 5 6 8 5 2 7
      • eBook
        9 7 8 1 9 0 8 8 1 8 0 4 1
      This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry.

Related subjects

Drug delivery

Drug design

Drug dispensing

Drug manufacturing and packaging

Drug metabolism disposition

Pharmaceutical analysis

Pharmaceutical biotechnology

Pharmaceutical quality control

Pharmaceutical science general

Pharmaceutical technology

Pharmacoeconomics

Pharmacoepidemiology

Pharmacotherapy

Pharmacy

Pharmacy management