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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Adolescent Psychosis

    Clinical and Scientific Perspectives
    • 1st Edition
    • Ingrid Agartz + 1 more
    • English
    Adolescent Psychosis: Clinical and Scientific Perspectives presents new methodologies and novel scientific findings, with a comprehensive orientation into the genetics, phenomenology, nosology, and long-term outcome of adolescent early-onset psychosis research. This volume discusses recent epidemiological studies, along with co-morbid aspects associated with other neurodevelopmental syndromes and somatic diseases. The book also provides suggestions for future research using a translational perspective, from genes to the clinic to and relevant phenotypes, biomarkers, treatment options and etiological aspects. Topics discussed bring together expert researchers in the field to represent different perspectives and future possibilities.

  • Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders

    • 1st Edition
    • Volume 168
    • English
    Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinson’s disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders.

  • Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

    • 1st Edition
    • Elena L. Paley
    • English
    Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer’s disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold’s reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book.

  • Tratamiento integral del ictus

    • 7th Edition
    • James C. Grotta + 7 more
    • Spanish
    Título derivado del libro de referencia internacional sobre el abordaje integral del ictus, Grotta, que recoge todos los temas relacionados con el tratamiento clínico de esta patología excluyendo así toda la parte vinculada al tratamiento quirúrgico. Esta obra incluiría los diferentes enfoques terapéuticos de esta patología recogiendo en su índice un total de 12 capítulos. Considerando que el abordaje del ictus tiene un enfoque totalmente transversal, el objetivo que se persigue con este derivado es que cualquier profesional NO neurólogo tenga a su disposición el contenido esencial para la asistencia de un paciente que ha sufrido un accidente cerebrovascular. Este derivado, al igual que la obra de referencia, está escrito por los mayores expertos de mundo en la materia e incorpora los resultados de las investigaciones más recientes realizadas en cuanto al manejo de la patología. Igualmente, la parte de terapia farmacológica está completamente actualizada incluyendo los últimos hallazgos en esta área.

  • Encyclopedia of Sleep and Circadian Rhythms

    • 2nd Edition
    • Clete Kushida
    • English
    Encyclopedia of Sleep and Circadian Rhythms, Second Edition, Six Volume Set is the most comprehensive work on sleep and circadian rhythms. This completely revised new edition, comprised of contributions from 450 renowned authorities in the field, covers what is new and known in the field. In addition to thorough coverage of the basics (physiology, sleep disorders etc.), this new edition includes a thorough examination of circadian rhythms that manage the sleep-wake cycle. Although this area is highly intertwined with sleep, it is a scientific discipline in and of itself, and will broaden the appeal of this work to health care providers and scientists. Other sections of interest explore consumer wearable devices to track sleep and circadian rhythms, artificial intelligence algorithms to detect sleep and abnormal sleep-related conditions, and new technology to treat sleep and circadian rhythm disorders. This book will be an ideal and primary reference resource for students, trainees, technologists, basic/clinical scientists, physicians, advanced practice providers, psychologists, nurses, and other medical and research personnel who want to explore any topic within the sleep and circadian rhythm field.

  • Neuropalliative Care

    Part II
    • 1st Edition
    • Volume 191
    • English
    Neuropalliative Care, Part Two, Volume 191 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.

  • Primer on the Autonomic Nervous System

    • 4th Edition
    • Italo Biaggioni + 5 more
    • English
    Primer on the Autonomic Nervous System, Fourth Edition provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book's 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored.

  • Handbook of Cognitive Behavioral Therapy by Disorder

    Case Studies and Application for Adults
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Pregnancy, childbirth, childhood, adolescence, and aging can be beset with adverse changes in psychobiology and behavior. Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging will better readers’ understanding of a variety of conditions and the applicability of CBT therapy as a treatment. Featuring chapters on postnatal anxiety and depression, insomnia, and dysmorphia, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues affecting individuals at the start and end of their lives. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

  • Handbook of Lifespan Cognitive Behavioral Therapy

    Childhood, Adolescence, Pregnancy, Adulthood, and Aging
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Mental illness and the variety of conditions, disorders, and phobias associated with it impact not only the individual but also the family unit, the community, and society at large. Handbook of Cognitive Behavioral Therapy by Disorder: Case Studies and Application for Adults will better readers’ understanding of a variety of these conditions in adults specifically and the applicability of CBT therapy as a treatment. Featuring chapters on schizophrenia, bipolar disorder, dysmorphia, depression, and anxiety, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues in adults. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

  • Determinants of Addiction

    Neurobiological, Behavioral, Cognitive, and Sociocultural Factors
    • 1st Edition
    • Justin R. Yates
    • English
    Why can two people use a drug and one person becomes addicted while the other does not? Determinants of Addiction: Neurobiological, Behavioral, Cognitive, and Sociocultural Factors unravels the complexities underlying addiction to understand how individual factors at the genetic, cellular, anatomical, cognitive–behavioral... and sociocultural level can influence susceptibility to substance use disorders. The first section reviews the neurobiological determinants of addiction and examines how drugs hijack the reward pathway and alter numerous neurotransmitter systems such as dopamine. The second section covers the behavioral–cognitive determinants of addiction such a conditioning, memory processes, and decision-making. The final section examines individual differences in addiction vulnerability, with a focus on personality factors, sociocultural factors, sex/gender, and stress. The book references commonly used drugs such as nicotine, ethanol (alcohol), opioids, and cocaine.

  • Spinal Interneurons

    Plasticity after Spinal Cord Injury
    • 1st Edition
    • Lyandysha Viktorovna Zholudeva + 1 more
    • English
    The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons that process information within local circuits, and have an incredible ability for neuroplasticity, whether due to persistent activity, neural injury, or in response to disease. Although, by definition, their axons are restricted to the same structure as the soma (in this case the spinal cord), spinal interneurons are capable of sprouting and rewiring entire neural circuits, and contribute to some restoration of disrupted neural communication after injury to the spinal cord (i.e., “bypassing” the lesion site). Spinal Interneurons provides a focused overview of how scientists classify interneurons in general, the techniques used to identify subsets of interneurons, their roles in specific neural circuits, and the scientific evidence for their neuroplasticity. Understanding the capacity for neuroplasticity and identity of specific spinal interneurons that are optimal for recovery, may help determine cellular candidates for developing therapies. Spinal Interneurons provides neuroscientists, clinicians, and trainees a reference book exclusively concentrating on spinal interneurons, the techniques and experiments employed to identify and study these cells as part of normal and compromised neural circuits, and highlights the therapeutic potential of these cells by presenting the relevant pre-clinical and clinical work to date. People in industry will also benefit from this book, which compiles the latest in therapeutic strategies for targeting spinal interneurons, what considerations there are for the development and use of treatments, and how such treatments can not only be translated to the clinic, but how existing treatments should be appropriately reverse-translated to the bench.

  • Neurocircuitry of Addiction

    • 1st Edition
    • Nicholas W. Gilpin
    • English
    People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction.

  • Principles of Cognitive Rehabilitation

    • 1st Edition
    • Vahid Nejati
    • English
    Principles of Cognitive Rehabilitation is designed to familiarize readers with the deep-rooted principles of cognitive rehabilitation and cognitive training. Presenting a new comprehensive framework in cognitive rehabilitation for therapeutic, educational, and research purposes, this volume introduces five components that are introduced for cognitive rehabilitation, including primary principles, patient, practitioner, program, and process (5Ps). Detailing the developmental stages of a program will help readers understand the logistics of cognitive interventions and also help them to design and evaluate their own therapeutic interventions.

  • Microbiome in Neurological Disease

    • 1st Edition
    • Volume 167
    • English
    Microbiome in Neurological Disease, Volume 167 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Section in this new release cover Intersections of the microbiome and early neurodevelopment, Microbiome influences on neuro-immune interactions, The genomes of Parkinson’s disease, Experimental contributions of the microbiome to Parkinson’s disease, The foundations of microbiome contributions to Alzheimer’s disease, Immunologic pathways by which the gut microbiota influences Alzheimer’s disease, Role of the gut microbiome in Huntington’s Disease, and much more.

  • Handbook of Animal Models in Neurological Disorders

    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Handbook of Animal Models in Neurological Disorders will better readers’ understanding of a large variety of animal models and their applicability in studying a number of neurological disorders. Featuring sections on brain injury, stroke and neuroinflammation, this volume discusses in detail the utility, success and pitfalls of multiple models for each condition. Multiple disorders are covered, ranging from neurodegenerative diseases like Alzheimer’s, Parkinson’s, and ALS, to multiple sclerosis, headache, migraine, and others. With expert authors, this book has applicability for anyone pursuing neuroscience or biomedical research working to better understand, study and ultimately treat neurological dysfunction.

  • Central Nervous System Infections, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 33-1
    • Tchoyoson Lim
    • English
    In this issue of Neuroimaging Clinics, guest editor Dr. Tchoyoson Lim Choie Cheio brings his considerable expertise to the topic of Central Nervous System Infections. Infections can involve any part of the CNS and often, multiple parts of the CNS are involved at the same time. The imaging surrounding them is constantly evolving, and in this issue, key international experts provide a thorough update of the imaging of these common and pervasive infections.

  • Outpatient Neurology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 41-1
    • Doris Kung + 1 more
    • English
    In this issue of Neurologic Clinics, guest editors Drs. Doris Kung and Everton A. Edmondson bring their considerable expertise to Outpatient Neurology. Top experts in the field cover key topics such as neck pain; how to read neurophysiology reports for the non-neurophysiologis... trigeminal neuralgia; epilepsy: choosing the best AED for your patient; insomnia: differential diagnosis and treatment options; dementia: management of psychiatric symptoms; and more.

  • Current Challenges in Cell Therapy for Neurodegenerative Diseases

    • 1st Edition
    • Volume 166
    • English
    Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington’s disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington’s Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more. Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson’s and Huntington’s disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovatio... in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease.

  • Neuroimaging in Parkinson’s Disease and Related Disorders

    • 1st Edition
    • Marios Politis + 2 more
    • English
    Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson’s and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders. Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s disease and related disorders.

  • Epilepsy, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 40-4
    • Steven C. Schachter
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Steven C. Schachter brings his considerable expertise to the topic of Epilepsy. Top experts in the field cover key topics such as telemedicine and epilepsy care; wearable technologies and mobile apps in the evaluation and treatment of epilepsy; effects of maternal use of AEDs on child development; sleep and epilepsy; dietary treatments for epilepsy; and more.

  • Posttraumatic Epilepsy

    Basic and Clinical Aspects
    • 1st Edition
    • Carrie R. Jonak + 2 more
    • English
    Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on the recent basic and clinical science developments in the field of posttraumatic epilepsy. This book provides a clear understanding of the history of studies and epidemiology of posttraumatic epilepsy after head injury. The book also considers the neuropathology of posttraumatic epilepsy and clinical trials of antiepileptogenic agents evaluated after traumatic brain injury. The book covers the basic science of animal models of traumatic brain injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors explore potential mechanisms and novel therapeutic approaches to prevent posttraumatic epilepsy. The book is written for basic and clinical researchers in neuroscience as well as for clinicians treating patients with epilepsy.

  • Athlete Mental Health and Performance Optimization

    The Optimum Performance Program for Sports (TOPPS)
    • 1st Edition
    • Brad Donohue + 1 more
    • English
    Athlete Mental Health and Performance Optimization: The Optimum Performance Program for Sports (TOPPS)introduces TOPPS, which provides structured protocols to assist with recruitment, engagement, screening, assessment and performance optimization. The book presents step-by-step instructional guidelines, real-world case examples, screening and assessment questionnaires, scoring instructions, intervention handouts and worksheets that complement intervention. TOPPS has demonstrated significantly improved relationships with teammates and coaches, decreased substance use and psychiatric symptoms, and decreased factors interfering with sport performance. These results have been sustained in follow-up and has been shown to have improved outcomes regardless of mental health diagnostic severity. The Book's first three chapters introduce performance optimization orientation, theories and evidence supporting TOPPS, general assessment and intervention approaches, psychometrically-val... measures and strategies used to address culture, methods of establishing a culture of optimization and requisite infrastructure within the respective system, and therapeutic style, techniques and implementation strategies. Remaining chapters show how to implement TOPPS.

  • Neuroimaging Anatomy, Part 2: Head, Neck, and Spine, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 32-4
    • Tarik F. Massoud
    • English
    In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 2: Head, Neck, and Spine. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part two of a two-part series on neuroimaging anatomy that focuses on the head, neck, and spine. Each article addresses a specific area such as the orbits, sinonasal cavity, temporal bone, pharynx, larynx, and spinal cord.

  • Nanomedicine-Based Approaches for the Treatment of Dementia

    • 1st Edition
    • Umesh Gupta + 1 more
    • English
    Nanomedicine-Based Approaches for the Treatment of Dementia explores a wide range of promising approaches for the diagnosis and treatment of dementia. The book begins with introductory sections on dementia and brain ailments that are followed by further chapters that discuss detailed information about challenges of drug delivery across the blood-brain barrier as well as the current status. This book helps readers design and develop novel drug delivery systems and devices for the treatment of dementia that take advantage of recent advances in nanomedical technologies. Numerous drug delivery systems have been developed recently for dementia. Unfortunately, most of them are ineffective since dementia is not a single disease. It is an umbrella term for several neurodegenerative conditions which alter brain functions. Due to this, there is an urgent need for innovative technologies/nano drug delivery systems to improve the targeting and delivery of therapeutic as well as diagnostic agents specifically for treating dementia.

  • Cerebrospinal Fluid and Subarachnoid Space

    Volume 2: Pathology and Disorders
    • 1st Edition
    • R. Shane Tubbs + 4 more
    • English
    Cerebrospinal Fluid and Arachnoid Space Volume 2: Pathology and Disorders is the first book devoted to the comprehensive clinical anatomy of the cerebrospinal fluid for neurosurgeons, neurologists, and neuroscientists. Knowledge of the cerebrospinal fluid (CSF) and the subarachnoid space is necessary for almost all fields of medicine. The book covers a wide swath of topics related to CSF with a focus on topics relevant to neuroscience specialists including researchers, neurologists, neurosurgeons, and neuroradiologists. Topics span from neuroanatomy, neurophysiology, CSF in different disease states and more. Various fresh and fixed cadaveric photographs helps readers obtain a better understanding of anatomy and complications related to CSF.

  • Cerebrospinal Fluid and Subarachnoid Space

    Volume 1: Clinical Anatomy and Physiology
    • 1st Edition
    • R. Shane Tubbs + 4 more
    • English
    Cerebrospinal Fluid and Subarachnoid Space: Volume 1: Clinical Anatomy and Physiology is the first book devoted to the comprehensive clinical anatomy of the cerebrospinal fluid for neurosurgeons, neurologists, and neuroscientists. Knowledge of the cerebrospinal fluid (CSF) and the subarachnoid space is necessary for almost all fields of medicine. The book covers a wide swath of topics related to CSF with a focus on topics relevant to neuroscience specialists including researchers, neurologists, neurosurgeons, and neuroradiologists. Topics span from neuroanatomy, neurophysiology, CSF in different disease states and more. Various fresh and fixed cadaveric photographs helps readers obtain a better understanding of anatomy and complications related to CSF.

  • Neurodivergence and Architecture

    • 1st Edition
    • Volume 5
    • English
    Neurodivergence and Architecture, Volume Five, the latest release in the Developments in Neuroethics and Bioethics series, focuses on the new and fascinating ethical and legal challenges posed by neurotechnology and its global regulation. Topics in this new release cover STS on architecture, Embodied Rhetoric/ Disability Studies, Autoethnography, Bioethics/Materialis... Feminism, Advocacy, Cultural Commentary: Being Autistic Together, An autistic perspective on built spaces, Empty spaces and refrigerator boxes: making autistic spaces, On the Losing Myself Project, Neither Use nor Ornament (NUNO) project, Madness and (Be)coming Out Within and Through Spaces of Confinement, and more.

  • Artificial Intelligence for Neurological Disorders

    • 1st Edition
    • Ajith Abraham + 3 more
    • English
    Artificial Intelligence for Neurological Disorders provides a comprehensive resource of state-of-the-art approaches for AI, big data analytics and machine learning-based neurological research. The book discusses many machine learning techniques to detect neurological diseases at the cellular level, as well as other applications such as image segmentation, classification and image indexing, neural networks and image processing methods. Chapters include AI techniques for the early detection of neurological disease and deep learning applications using brain imaging methods like EEG, MEG, fMRI, fNIRS and PET for seizure prediction or neuromuscular rehabilitation. The goal of this book is to provide readers with broad coverage of these methods to encourage an even wider adoption of AI, Machine Learning and Big Data Analytics for problem-solving and stimulating neurological research and therapy advances.

  • Covid-19 and Parkinsonism

    • 1st Edition
    • Volume 165
    • English
    Covid-19 and Parkinsonism, Volume 165 in the International Review in Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters that cover a variety of topics, including Parkinsonism associated with viral infections, Covid-19 and nervous system pathology: bench to bedside, Prevalence of Covid-19 in Parkinson’s Disease: acute settings and hospital, Covid-19 and Parkinson’s Disease: clinical features, long COVID, Smell deficits in Covid-19 and possible links with Parkinson’s Disease, Spotlight on non-motor symptoms and Covid-19, and a Summary of treatment paradigms in Parkinson’s Disease patients and Covid-19. Additional sections cover Covid-19 and Parkinson’s Disease: nursing care, vaccination, telemedicine services, impact on advanced therapies, Covid-19-induced parkinsonism: Real life phenoconversion cases, Loneliness and impact of lockdown on Parkinson’s Disease patients during the Covid-19 pandemic, Parkinson’s Disease and Covid-19: Impact of ethnicity and palliative care, and more.

  • Febrile Seizures

    New Concepts and Consequences
    • 2nd Edition
    • Tallie Z. Baram + 2 more
    • English
    Febrile seizures are the most common seizures in infants and children worldwide, This fact provides strong impetus to study and understand them and their consequences, and consider their treatment. These topics were the focus of the first edition of this book. The 20 years since the publication of this first edition have witnessed an explosion of new information about febrile seizures, meriting this new edition. Key advances have been made in the genetics and neurobiological underpinnings of febrile seizures and especially the very long fever-related seizures called febrile status epilepticus. The role of neuroinflammatory factors in the emergence of these seizures and their consequences, the demonstration of unique clinical and neuroradiological aspects of febrile status epilepticus, and the prospect of predictive (bio)markers to identify and characterize cognitive and epilepsy outcomes are exciting and important. In this edition, the authors and editors tackle these developments in chapters addressing the questions of parents, physicians, allied health care professionals and basic and translational scientists. 　

  • Collective Memory

    • 1st Edition
    • Volume 274
    • English
    Collective Memory, Volume 274 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of interesting topics, including Deriving testable hypotheses through an analogy between individual and collective memory and updated information on Collective future thinking: Current research and future directions.

  • Neurotoxicity of Drugs of Abuse

    • 1st Edition
    • Volume 8
    • English
    Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system. The neurotoxicity potential of several agents including marijuana, fentanyl, and ketamine are carefully reviewed, and their short-term and chronic effects are categorized. Pharmacokinetic profiles as well as mechanisms of action for these and other drugs of abuse such as alcohol and nicotine are also evaluated. The implications of short and long-term abuse for agents such as PCP are also characterized. The reader will come away with a fuller understanding of the adverse effects of drugs of abuse on the nervous system.

  • Teleneurología

    Guía para implementar la telemedicina y la telepsicología en la práctica clínica
    • 1st Edition
    • Randall Wright
    • Spanish
    En el cambiante escenario médico actual, el número de profesionales que están incorporando la telemedicina a su práctica clínica es mayor que nunca. Teleneurología proporciona respuestas exhaustivas y prácticas a las numerosas preguntas que los médicos tienen sobre la implementación y la expansión de una consulta de teleneurología. Este libro, que abarca desde las perspectivas históricas hasta las posibilidades futuras en este campo en constante evolución, contiene la información necesaria para utilizar con éxito esta nueva y prometedora opción a la hora de proveer una asistencia y unos cuidados óptimos y adaptables a cada paciente.

  • Bradley y Daroff. Neurología clínica

    • 8th Edition
    • Joseph Jankovic + 3 more
    • Spanish
    La nueva edición de Bradley y Daroff. Neurología clínica es una práctica herramienta de consulta para neurólogos tanto en ejercicio como en formación. Proporciona, con un estilo claro y directo, información actualizada basada en la evidencia, reforzada por contenidos interactivos, así como algoritmos de tratamiento y numerosas imágenes, que le ayudarán a estar al día en esta especialidad rápidamente cambiante. Esta obra en dos volúmenes es ideal para la consulta diaria, ya que presenta los contenidos organizados por síntomas/signos de presentación y por entidades patológicas específicas, lo cual agiliza el acceso a la información y, por tanto, la toma de decisiones clínicas. Más de 150 colaboradores, dirigidos por Joseph Jankovic, John C. Mazziotta, Scott L. Pomeroy y Nancy J. Newman, proporcionan directrices actualizadas para diagnosticar y tratar eficazmente los distintos trastornos neurológicos.

  • Imagerie de l'orbite, du labyrinthe membraneux et de la base du crâne

    • 1st Edition
    • Francis Veillon + 1 more
    • French
    L’interprétation radiologique de la base du crâne est délicate car la structure anatomique de la région est singulièrement complexe.Ce nouveau volume de la collection des Syllabus de la Société française de radiologie propose un état de l’art de l’imagerie de l’orbite, du labyrinthe membraneux et de la base du crâne. Les connaissances à maîtriser pour réaliser les IRM et tomodensitométries de ces différentes régions sont détaillées. Pour chaque zone topographique sont abordées la radioanatomie et les pathologies de type infectieux, tumoral, malformatif et lésionnel. Sont également présentés la place des techniques avancées dans le diagnostic et la prise en charge des pathologies ophtalmiques, ainsi que les progrès en cours ou attendus grâce à l’intelligence artificielle dans l’étude des troubles cochléovestibulaires... plus de 500 clichés, cet ouvrage constitue la référence pédagogique actuelle sur le sujet. Il est indispensable pour les internes et radiologues qui interprètent cette région anatomique, ainsi que pour les neurologues, neurochirurgiens, ORL et ophtalmologues désireux de mieux demander et mieux comprendre les examens d’imagerie. LES AUTEURSFrancis Veillon est professeur des universités et praticien hospitalier au service d’imagerie médicale 2 à l’hôpital de Hautepierre, CHRU de Strasbourg.Augustin Lecler est maître de conférences des universités et praticien hospitalier au service de radiodiagnostic et imagerie médicale de l’hôpital Fondation Adolphe de Rothschild à Paris.Arnaud Attyé est praticien hospitalier au service de neuro-imagerie et d’IRM de l’hôpital Michallon du CHU Grenoble Alpes, laboratoire GeodAIsics à Grenoble.Anne-Laure Gaultier est praticien hospitalier au service d’imagerie de l’hôpital européen Georges Pompidou à Paris.

  • Phenotyping of Human iPSC-derived Neurons

    Patient-Driven Research
    • 1st Edition
    • Elizabeth D. Buttermore
    • English
    Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification.

  • Neuroinflammation in Vascular Dementia

    • 1st Edition
    • Gary Rosenberg
    • English
    Neuroinflammation in Vascular Dementia describes the molecular mechanisms that drive this transition to mixed pathology, along with the newer lifestyle and pharmacological approaches that can reduce the incidence of dementia. The book describes the practical aspects of neuroimaging methods, along with novel neuroimaging methods, using MRI, that are becoming important clinically. The author also discusses how the diagnosis of dementias will be greatly aided by biomarkers from neuroimaging, blood and CSF biochemistry and neuropsychological testing in the future. This information will be used in precision medicine to design treatment strategies based on the most likely causes of the disease. Dementia research has undergone dramatic growth driven by current and projected increases in the aging of the population, and thus leading to a larger number of patients with dementia by 2050. Hence, advances in neuroimaging, brain chemistry, and genetics have accelerated our understanding of diseases that lead to cognitive decline.

  • The Neurosurgical Consult Book

    • 1st Edition
    • Risheng Xu + 2 more
    • English
    Written by neurosurgery residents for neurosurgery residents and other providers, The Neurosurgical Consult Book focuses on the initial care and treatment of the neurosurgical consult patient, providing the key guidance you need when quick clinical management decisions are critical. You will learn to recognize the acuity of patient presentation and determine how to immediately triage the needs of the patient at an appropriate level of care. This portable, practical guide helps you quickly steer neurosurgical patients to medical stability and safety until a definitive treatment plan is implemented.

  • Neuropalliative Care

    PART I
    • 1st Edition
    • Volume 190
    • English
    Neuropalliative Care, Part One, Volume 190 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.

  • Neurologic Localization and Diagnosis

    • 1st Edition
    • Eli E. Zimmerman + 3 more
    • English
    Written for a wide range of neurology and non-neurology clinicians and residents, Neurologic Localization and Diagnosis: Differential Diagnosis by Complaint-Based Approach is a concise, easy-to-use guide to establishing a neurologic diagnosis. This unique learning resource uses an algorithmic, complaint-based approach to localizing the condition, developing a list of differential diagnoses, and focusing further evaluation on establishing the diagnosis. Leading neurologists provide up-to-date, practical guidance for neurology residents, medical students, and neurologists, as well as nurse practitioners, physician assistants, and non-neurology physicians.

  • Respiratory Neurobiology

    Physiology and Clinical Disorders, Part II
    • 1st Edition
    • Volume 189
    • English
    Respiratory Neurobiology: Physiology and Clinical Disorders, Part Two, Volume 189 is one of two volumes on the neurology of breathing. This volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases, while volume one focuses on the neurophysiology of breathing.

  • Handbook of Neuro-Oncology Neuroimaging

    • 3rd Edition
    • Herbert B. Newton
    • English
    With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology.

  • Genetics and Neurobiology of Down Syndrome

    • 1st Edition
    • Bani Bandana Ganguly
    • English
    Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development.

  • Autophagy Dysfunction in Alzheimer's Disease and Dementia

    • 1st Edition
    • Tadanori Hamano + 1 more
    • English
    Autophagy Dysfunction in Alzheimer’s Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer’s. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer’s and other neurodegenerative diseases.

  • Sex and Gender Differences in Neurological Disease

    • 1st Edition
    • Volume 164
    • English
    International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Cannabis and the Developing Brain

    • 1st Edition
    • Miriam Melis + 1 more
    • English
    Marijuana is the most commonly used psychotropic drug in the United States, after alcohol. With the legalization and decriminalization of cannabis, momentum continues to build and propelled by the reduction of stigma associated to its consumption, there is growing concern regarding the long-term impact on brain function and behavior. Cannabis and the Developing Brain aims to provide comprehensive research on the effects of cannabis during neurodevelopment stages (i.e., perinatal and adolescent ages). This book introduces readers to vivo neural circuits, molecular and cellular mechanisms affected by cannabis exposure during three different temporal windows of brain vulnerability. Second, it offers a unique insight to shared neurobiological features of cannabinoid exposure during different developmental periods. Lastly, Cannabis and the Developing Brain determines the adverse impact of developmental cannabinoid exposure on specific cognition, emotion and behaviors.

  • L'Adulte avec un trouble dys-exécutif

    L'accompagner dans sa vie quotidienne, sociale et professionnelle
    • 1st Edition
    • Alain Moret
    • French
    Les recommandations pour la prise en charge du trouble dys-exécutif s’adressent à l’enfant, afin de faciliter son éducation et sa scolarité. Le trouble s’améliore parfois avec l’avancée en âge, mais il reste très présent à l’âge adulte. Se pose alors la question de l’autonomie au quotidien en termes de professionnalisation... d’insertion sociale et de citoyenneté pour laquelle l’entourage doit souvent développer ses propres outils car rien n’est formalisé pour accompagner l’adulte.L’ouvrage aborde les différentes situations rencontrées par l’adulte dys-exécutif, des plus anodines de la vie quotidienne aux plus personnelles ou aux plus décisives quant à son style de vie, et propose des solutions pratiques et des conseils d’adaptation ou d’aménagements pour y faire face.Plus que chez l’enfant, les stratégies proposées pour aider l’adulte dys-exécutif dans sa prise d’autonomie sont pensées pour ménager sa personnalité et son libre arbitre.La description des différentes situations intègre à la fois le vécu de l’adulte dys-exécutif et celui d’autrui, en mettant l’accent sur les quiproquos et des interprétations erronées en fonction du contexte qui peuvent générer incompréhension et perte d’estime de soi.L’ouvrage interroge chacun, qu’il soit parent ou professionnel, sur ce que signifie réellement l’inclusion dans un environnement qui n’a pas les clés pour appréhender correctement les interactions avec l’adulte dys-exécutif, la définition de son projet de vie et le respect de sa volonté.

  • Respiratory Neurobiology

    Physiology and Clinical Disorders, Part I
    • 1st Edition
    • Volume 188
    • English
    Respiratory Neurobiology: Physiology and Clinical Disorders, Part One, Volume 188 is one of two volumes on the neurology of breathing. This volume focuses on the neurophysiology of breathing, while the second volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases.

  • The Temporal Lobe

    • 1st Edition
    • Volume 187
    • English
    The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe. This volume summarizes research on the anatomy and function of the temporal lobe under both normal and pathological conditions. In addition, it discusses the interactions of the temporal lobe with other brain structures. The book highlights the role of the temporal lobe in language processing as well as vision, object, face recognition and processing. The book also discusses the temporal lobe's role in reading, speech and the processing of color, music, action and memory. Temporal lobe disorders, assessments and treatments are also covered, including encephalitis, Alzheimer’s, epilepsy, Korsakov’s syndrome, and more.

  • Imaging of Headache, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 40-3
    • Sangam Kanekar
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Sangam Kanekar brings his considerable expertise to the topic of Imaging of Headache. Top experts in the field cover key topics such as headache attributed to disorder of the cranium and base of the skull; role of CT and MRI in evaluation of headache due to paranasal sinus and teeth disorder; imaging of painful ophthalmologic disorders; role of MRI and CT in the evaluation of headache in pregnancy and postpartum period; assessment and imaging of pediatric and adolescent headache; and more.

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