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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Electrocardiography of Channelopathies

      • 1st Edition
      • November 27, 2024
      • Manlio F. Márquez-Murillo
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 3 4 4 0
      • eBook
        9 7 8 0 4 4 3 2 2 3 4 5 7
      Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist introduces readers to the inherited arrhythmia syndromes that are a leading cause of sudden cardiac death. As the ECG is the cornerstone of identifying inherited arrhythmia syndromes, this cutting-edge book is a critical resource to guide cardiologists in using the technology for optimum diagnosis and treatment of their patients. It clearly delineates the differences between each syndrome to improve accuracy and health outcomes. Its easy portability belies a vast knowledge base for use by clinicians in the moment as well as by researchers in the laboratory.This book illuminates diseases such as Short and Long QT Syndromes, Andersen-Tawil Syndrome, Brugada Syndrome, Polymorphic Ventricular Tachycardia, and Early Repolarization syndrome. Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist will no doubt become a go-to reference for experienced clinicians seeking confirmation of their diagnoses, as well as those newer to the field seeking guidance in ECG interpretation.

    • International and Life Course Aspects of COVID-19

      • 1st Edition
      • June 13, 2024
      • Rajkumar Rajendram + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 5 6 4 8 2
      • eBook
        9 7 8 0 3 2 3 9 5 6 4 9 9
      International and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.

    • Cellular Senescence and Aging

      • 1st Edition
      • Volume 181
      • January 12, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 8 9 6 1
      • eBook
        9 7 8 0 4 4 3 1 8 8 9 7 8
      Cellular Senescence and Aging, Volume 181 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as assessing polyglutamine tract aggregation in the nematode Caenorhabditis elegans, Generation of glial cell-derived neurotrophic factor (gdnf) morphants in zebrafish larvae by cerebroventricular microinjection of vivo morpholino, Methods for detection of mitochondrial reactive oxygen species in senescent cells, Assessment of cell cycle progression and mitotic slippage by videomicroscopy, The original colorimetric method to detect cellular senescence, and more.Additional sections cover Assessing microbiota composition in the context of aging, Assessing chronological aging in Saccharomyces cerevisiae, Image processing and supervised machine learning for retinal microglia characterization in senescence, Measuring telomerase activity using TRAP assays, High throughput assessment of cellular senescence, Detection of radiation-induced senescence by the Debacq-Chainiaux protocol: Improvements and upgrade in the detection of positive events, Dynamic and scalable assessment of the senescence-associate... secretory phenotype (SASP), Flow cytometry-assisted quantification of cell cycle arrest in cancer cells treated with CDK4/6 inhibitors, and more.

    • Strategies for Overcoming Chemotherapy Resistance in Cervical Cancer

      • 1st Edition
      • Volume 21
      • January 23, 2024
      • Zodwa Dlamini
      • English
      • Hardback
        9 7 8 0 4 4 3 2 8 9 8 5 9
      • eBook
        9 7 8 0 4 4 3 2 8 9 8 6 6
      Strategies for Overcoming Chemotherapy Resistance in Cervical Cancer: From Molecular Insights to Precision Solutions, Volume 21 highlights different strategies to reverse chemotherapy resistance in cervical cancer. The book puts a strong focus on strategies to reverse chemotherapy resistance as well as strategies for early detection of the resistance, enhancing precision oncology in terms of patient care and maximizing patient management. The book also looks at virally induced resistance to chemotherapy and recommends combination therapies that can maximize the reversal of this resistance.In 10 chapters, the book not only gives an overview of cervical cancer and chemotherapy as treatment, but also investigates resistance to chemotherapy and treatment for resistance. It defines treatment mechanisms, options, and limitations to beat chemotherapy resistance and the reversal of the resistance mechanisms. It gives insights into future directions of cervical cancer treatment using epigenetic silencing, chemotherapy splicing, the involvement of MicroRNAs to chemotherapy resistance, and the application of Artificial Intelligence.

    • Epigenetic Regulation of Cancer-Part C

      • 1st Edition
      • Volume 387
      • August 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 4 4 6 2
      • eBook
        9 7 8 0 4 4 3 2 1 5 4 7 6
      Epigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic biomarkers in breast cancer, Contribution of epigenetics to virus-driven cancer, Cancer metabolism and epigenetics, Technologies for epigenome editing, Epigenetics and cancer stemness, Epigenetic modifications in obesity-associated cancers, Epigenetics in cf microRNA in blood of solid tumors, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, and more.Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.

    • Medical Geology of Africa

      • 1st Edition
      • June 14, 2024
      • Theophilus Clavell Davies
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 7 4 8 7
      • eBook
        9 7 8 0 1 2 8 1 8 7 4 9 4
      Medical Geology of Africa: A Research Primer explores the connection between geological materials and processes and human health in Africa. A synopsis on current state of knowledge is given for a selection of some of the more critical issues in African Medical Geology. Gaps in knowledge are exposed, and directions are given for navigating the most recent bibliography of the more pressing Medical Geology issues by future researchers. Guidelines for researching gaps in knowledge are prescribed and are intended for researchers eager to make urgently needed contributions towards an understanding of how judicious exploitation of the interphase between geology and health can help unravel environmental disease causality, especially of those (diseases) of unknown aetiology (DUA) which are so widespread on the African Continent.

    • Gallstone Formation, Diagnosis, Treatment and Prevention

      • 1st Edition
      • March 11, 2024
      • Rajani Sharma + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 6 0 9 8 1
      • eBook
        9 7 8 0 4 4 3 1 6 0 9 9 8
      Gallstone Formation, Diagnosis, Treatment, and Prevention describes the current scenario of gallstones and adopted treatment methods. It is a complete reference for researchers introducing new techniques to help prevent extreme treatments such as a cholecystectomy. This reference provides current knowledge and basic challenges of understanding gallstone formation, with all variations of composition, including complications of the treatment process. This content directs researchers to focus on gallstone mechanisms to design and develop new treatment methods. The book provides all possible factors for gallstone formation as well as preventative measures.

    • Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1

      • 1st Edition
      • Volume 2
      • July 24, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 4 5 6 3
      • eBook
        9 7 8 0 4 4 3 2 9 4 5 7 0
      Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1 deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examine their relationship with aging aim to target deteriorating redox signaling cascades, and will also focus on promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing will help adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress. However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity; it also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades. Redox-dependent second messengers are generated in subcellular locations according to specific rules and regulations. Their appearance depends on cellular needs in response to external and internal stimuli variations. A good understanding of the wound healing cascades, which deteriorate especially in advancing ages, is critical in developing the most appropriate approach. To understand the redox signaling mechanisms and healing cascades in wound healing, to pioneer new pharmacoactive drugs that can be developed based on these mechanisms, to reveal the deteriorating dynamics in the elderly patient group, and to propose new treatment methods suitable for the advanced age group.

    • Concepts and Methodology in Cancer Diagnostics

      • 1st Edition
      • November 5, 2024
      • Seema Nayak + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 5 9 3 1
      • eBook
        9 7 8 0 4 4 3 2 3 5 9 4 8
      Concepts and Methodology in Cancer Diagnostics: An Immunological, Biochemical and Molecular Approach provides an exclusive combination of all basics and recent techniques, methodology, and advancements in the field of cancer diagnostics. With a strong focus on the procedures and techniques involved in cancer diagnostics, content also gives insights into the molecular tests required for different tumors for the administration of targeted drugs and precision medicine. In 11 chapters. The book also introduces the methods and technologies based on DNA and RNA based biomarkers, biochemical and immunological markers, genetic signatures, epigenetic changes and exosomes in blood, and tissue and body fluids.Readers will find a compilation of imperative topics and lists of the necessary materials and reagents needed, step-by-step instructions, readily reproducible laboratory protocols, as well as tips on troubleshooting and known pitfalls. This book is a valuable resource for medical professionals and researchers who want to understand the concepts of validated protocols and methodologies in diagnosing cancer, its prognosis, and predictive value.

    • Machine Learning Models and Architectures for Biomedical Signal Processing

      • 1st Edition
      • November 5, 2024
      • Suman Lata Tripathi + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 1 5 8 3
      • eBook
        9 7 8 0 4 4 3 2 2 1 5 7 6
      Machine Learning Models and Architectures for Biomedical Signal Processing presents the fundamental concepts of machine learning techniques for bioinformatics in an interactive way. The book investigates how efficient machine and deep learning models can support high-speed processors with reconfigurable architectures like graphic processing units (GPUs), Field programmable gate arrays (FPGAs), or any hybrid system. This great resource will be of interest to researchers working to increase the efficiency of hardware and architecture design for biomedical signal processing and signal processing techniques.

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