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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Gene Transfer and Expression in Mammalian Cells

      • 1st Edition
      • Volume 38
      • October 24, 2003
      • S.C. Makrides
      • English
      • Paperback
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      The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression in mammalian cells. Other applications in widespread use involve screening of libraries of chemical compounds in drug discovery, and the development of cell-based biosensors.This book presents a state-of-the-art comprehensive coverage of the technical aspects of gene expression in mammalian cells, written by experienced scientists working at the forefront of the field.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 89
      • October 21, 2003
      • George F. Vande Woude
      • English
      • Hardback
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      The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics, including Mdm2 - a regulator of cell growth and death; the systematic progression of human cancer; seizing of T-cells by human T-cell leukemia/lymphoma virus type II; host cell dependent expression of latent Epstein-Barr virus genomes; and gene expression profiling of renal cell carcinoma and its implications in diagnosis prognosis and therapeutics.

    • Current Topics in Developmental Biology

      • 1st Edition
      • Volume 56
      • October 17, 2003
      • Gerald P. Schatten
      • English
      • Hardback
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      Together with other volumes in this series, Volume 56 of Current Topics in Developmental Biology presents thoughtful and forward-looking articles on developmental biology and developmental medicine. Reviews include: Selfishness in moderation: evolutionary success of the yeast plasmid Nongenomic actions of androgen in sertoli cells Regulation of chromatin structure and gene activity by Poly(ADP-ribose) polymerases Centromeres and Kinetochores, Who Needs 'Em? The Role of Non-centromeric Chromatin in Spindle Assembly Modeling Cardiogenesis: The Challenges and Promises of 3D Reconstruction Plasmid and Chromosome Traffic Control: How ParA and ParB Drive Partition The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.

    • Antiviral Nucleosides

      • 1st Edition
      • October 15, 2003
      • C.K. Chu
      • English
      • Paperback
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      • Up-to-date review on the chemistry and biology of nucleosides• Modern synthetic methodology• Comprehensive coverage of antiviral nucleosidesThis book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis.

    • Recognition of Carbohydrates in Biological Systems, Part B: Specific Applications

      • 1st Edition
      • Volume 363
      • October 10, 2003
      • English
      • Hardback
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      Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume, Recognition of Carbohydrates in Biological Systems, Part B: Specific Applications, and its companion, Volume 362, present state-of-the-art methodologies, as well as the most recent biological observations in this area.

    • Biotechnology Annual Review

      • 1st Edition
      • Volume 9
      • October 9, 2003
      • M.R. El-Gewely
      • English
      • Paperback
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      It is an exciting time to follow the new developments in the field of biotechnology and its wider applications in the different areas. The whole genomes of over 1000 viruses and over 100 microbes can now be found in Entrez Genome. The genomes represent both completely sequenced organisms and those for which sequencing is still in progress. The three main domains of life - bacteria, archaea, and eukaryota - are represented, as well as many viruses and organelles. The exponential increase of the sequence data lead to the development of the new "Bioinformatics" field in order to attempt making sense, at least biological sense, out of all the new and fast data.It will take also other techniques such as "functional genomics" to link the gap between a specific phenotype or a treatment and a gene sequence. Functional genomics tools are therefore important for the accurate molecular diagnosis/prognosis, target discovery validation needed for drug development and novel targets for antibiotics development. Functional genomics are also important for the confirmation of therapy in pharmacogenomics studies. Biotechnology is in many respects shaping our life and affecting our means of production and the creation of jobs. Progress in the applications of biotechnology depends on a wide base of basic as well as applied sciences. The output of biotechnology has already proved itself in many diverse fields from health tobiomining and from agriculture to enzyme "breeding". It is therefore difficult to follow all of the current as well as the potential applications of biotechnology.The objective of the Biotechnology Annual Review series is to attempt to provide readers with the needed indepth knowledge, by reviewing specific topics in biotechnology in each issue. The philosophy behind this series is to encourage good reviews to make it easier for readers to keep in touch with progress and applications of biotechnology. Reviews on topics related to regulatory affairs, social impact of biotechnology, biodiversity, biosafety, public acceptance and patent issues are also encouraged.

    • Pediatric Bone

      • 1st Edition
      • September 23, 2003
      • Francis H. Glorieux + 2 more
      • English
      • eBook
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      Pediatric Bone is the first book to be published to deal exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone which are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to the causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in children

    • Essential Medical Physiology

      • 3rd Edition
      • September 18, 2003
      • Leonard R. Johnson
      • English
      • Hardback
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      Essential Medical Physiology, Third Edition, deals with the principal subjects covered in a modern medical school physiology course. This thoroughly revised version includes chapters on general physiology as well as cardiovascular, respiratory, renal, gastrointestinal, endocrine, central nervous system, and integrative physiology. It contains clinical notes, chapter outlines with page numbers, 2-color figures throughout, and new chapters on Exercise, Diabetic Ketoacidosis, and Maternal Adaptations in Pregnancy. Among the contributors to this indispensible textbook are leading physiologists Leonard R. Johnson, Stanley G. Schultz, H. Maurice Goodman, John H. Byrne, Norman W. Weisbrodt, James M. Downey, D. Neil Granger, Frank L. Powell, Jr., James A. Schafer, and Dianna A. Johnson. This text is recommended for medical, graduate, and advanced undergraduate students studying physiology, physicians, and clinical specialists as well as anyone interested in basic human physiology.

    • International Review of Cytology

      • 1st Edition
      • Volume 227
      • September 15, 2003
      • Kwang W. Jeon
      • English
      • eBook
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      The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Contributors to this volume areViatcheslav M. Mikhailov, Y.C. Wong, XH Wang, PMT Ling, Armin Hallmann, and Carlos G. Dotti.

    • Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases

      • 1st Edition
      • Volume 30
      • September 12, 2003
      • A. Kuksis
      • English
      • Paperback
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      This book offers a wide ranging and review of cutting edge developments along with tried and tested methods for isolation, resolution and quantification of inositol phospholipids and inositol polyphosphates in both cells and tissues. It includes detailed and rigorous methodology for identification of molecular species of inositol phospholipids, including their phosphates and glycans, with numerous examples of specific applications. Wherever available, both chromatographic and mass spectrometricevidenc... is presented for specific phospholipid involvement in the biochemical transformations accompanying metabolic signalling events and, where possible, controversies have been resolved on basis of analytical ambiguity. The review of the lipidanalyses extends to products of phosphatidylinositol kinases, phosphatases and lipases. A general review chapter is included on metabolic signalling with special emphasis on the lipid products of 3-kinases. In view of the general lack of commercially available standards for inositol phospholipids and inositol phosphates, the book concludes with a chapter on the preparation and collection of chromatographic and mass spectrometric proof of their purity and identity.This book complements recent books and reviews on the mechanisms metabolic signalling, receptor binding and the polypeptide structure of the proteins involved in the various signalling pathways. It also complements those texts that deal exclusively with the chemical synthesis of the phosphatidylinositol... and their polyphosphates and glycans.

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