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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Updates on Osteoporosis Diagnosis and Therapy, An Issue of Endocrinology and Metabolism Clinics of North America

      • 1st Edition
      • Volume 53-4
      • October 26, 2024
      • Pauline M. Camacho
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 6 7 8 4
      • eBook
        9 7 8 0 4 4 3 3 1 6 7 9 1
      In this issue of Endocrinology and Metabolism Clinics of North America, guest editor Dr. Pauline Camacho brings her considerable expertise to the topic of Updates on Osteoporosis. Top experts in the field cover the latest updates in therapies, management, and guidelines for osteoporosis, in addition to updates on FRAX tools, promising agents, and anabolic agents.

    • Advances in Applied Microbiology

      • 1st Edition
      • Volume 128
      • July 25, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 5 8 4
      • eBook
        9 7 8 0 4 4 3 2 9 5 5 9 1
      Advances in Applied Microbiology, Volume 128 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

    • Targeting Signaling Pathways in Solid Tumors Part C

      • 1st Edition
      • Volume 389
      • October 11, 2024
      • English
      Targeting Signaling Pathways in Solid Tumors, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled

    • Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies

      • 1st Edition
      • May 24, 2024
      • Patricia Ordonez de Pablos
      • English
      Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies: Shaping Digital Future provides insight to the potential of advanced information technologies to build stronger healthcare systems, better quality healthcare services, and more resilient societies. The book covers two important regions: Gulf Region (Bahrein, Kuwait, Oman, Qatar, and UAE) and Asia, and explores how these countries develop policies for healthy aging and how digital tools can serve these goals. This book delivers a collection of relevant, innovative research works on digital healthcare, with four main goals: (1) to cover two geographical regions (Asia and Gulf Region) with important advances in digital healthcare; (2) to present case studies in the field of IT and digital health during the pandemic and analyze the lessons from these studies; (3) to evaluate the latest advances in the field of digital healthcare (especially Artificial Intelligence [AI], Big Data, Blockchain, and 5G); and (4) to discuss implications for main stakeholders (patients, doctors, IT experts, directors, and policy managers) and recommendations for policy makers in these two regions and elsewhere.

    • Terpene Synthases

      • 1st Edition
      • Volume 699
      • June 28, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 8 0 8 6
      • eBook
        9 7 8 0 4 4 3 2 3 8 0 9 3
      Terpene Synthases, Volume 700 in the Methods in Enzymology series, continues the legacy of this highly respected laboratory standard with its first dedicated collection on this important family of enzymes. Terpene synthases are a diverse set of enzymes that use exquisite mechanisms to form complex (poly)cyclic hydrocarbon skeletons. Chapters in this new volume include Structural analysis by X-ray crystallography and cryo-EM, Understanding mechanisms using stable isotopes, substrate analogs, or computational tools, Engineering fusion enzymes, Ancestral terpene cyclases, as well as the Sequence, structure, and function of non-canonical terpene synthases.

    • G4 biology

      • 1st Edition
      • Volume 695
      • March 21, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 7 7 4 6
      • eBook
        9 7 8 0 4 4 3 2 1 7 7 5 3
      G4 Biology, Volume 695 in the Methods in Enzymology series, highlights high value topics such as Assays to measure G4 resolution by DNA helicases, In gel staining methods of G4 DNA and RNA structures, Methods to probe the folding pathways of four-stranded intercalated cytosine-rich motifs at single base-pair resolution, Analyzing the effect of transcription coupled R-loop formation on G4 formation, Integrated Structural Biology for the study of higher-order G4 structures, Advancing the Study of Protein-G4 Interactions in DNA Repair: Insights from Biolayer Interferometry and Circular Dichroism Spectroscopy, Immunofluorescence microscopy (IF) of G-quadruplex and R-loops, and more.Additional chapters delve into Production of the anti-G-quadruplex antibody BG4 for efficient ChIP-seq and CUT&Tag analysis: from plasmid quality control to validation, Utility of intercalator displacement assays for screening of ligands for i-motif DNA structures, Potentiometric titrations to study ligand interactions with DNA i-motifs, Towards Profiling of the G-Quadruplex Targeting Drugs in the Living Human Cells Using NMR Spectroscopy, and Identification of bona fide G4-binding proteins, Observing Pif1 opening dsDNA and G4 in real time by manipulation under magnetic tweezers, and in vivo detection of DNA secondary structures using Permanganate/S1 Footprinting with direct adapter ligation and sequencing (PDAL-Seq).

    • Metabolomics of Bladder Cancer

      • 1st Edition
      • September 9, 2024
      • Vishwajeet Singh + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 8 8 1 9
      • eBook
        9 7 8 0 4 4 3 2 3 8 8 2 6
      Metabolomics of Bladder Cancer: An Emerging Application offers insights into the latest research methodologies and potential therapeutic applications. The book examines how applied research on the discovery of metabolomic biomarkers with prognostic and predictive value is needed to stratify patients into different risk groups, minimizing overtreatment and the risk of drug resistance development. In eight chapters, the book gives an in-depth analysis of recent findings in both fundamental and applied research, with a focus on the metabolomics approach and its potential for identifying major metabolic pathways that characterize various diseases and physiological states.It intuitively leads from the discovery of biomarkers for bladder cancer, to the metabolisms of glutamine and fatty acids and finalizes with a chapter on the metabolic effect of cancer therapy. Overall, this book is a comprehensive and insightful resource for researchers, clinicians, and academic professionals interested in the latest developments in bladder cancer research.

    • Biomechanics of the Aorta

      • 1st Edition
      • June 18, 2024
      • T. Christian Gasser + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 5 4 8 4 6
      • eBook
        9 7 8 0 3 2 3 9 5 4 8 5 3
      As biomechanics is fundamental to understanding the normal and pathological functions of the aorta, Biomechanics of the Aorta presents a holistic analysis of aortic physiology, clinical imaging, tissue and blood flow modeling. It investigates a wide range of topics from basic sciences (vascular biology, continuum mechanics, image analysis) to essential knowledge for clinical applications, including diagnostics, aortic rupture prediction, as well as surgical planning. Expert chapter authors describe and present computational studies and experimental benches, to mimic, understand and propose the best treatment of aortic pathologies.Divided into five parts, the book begins with an introduction to the fundamental aspects of the anatomy, biology, and physiopathology of the aorta, and then proceeds to present concepts of imaging and tissue/rheology characterization, tissue modeling and rupture, and flow modeling and algorithms. The final part dives into applications and case studies including transcatheter aortic valve implantation, aortic aneurysm rupture prediction, aortic dissections, and pharmacological treatments.

    • Mononuclear Non-heme Iron Dependent Enzymes

      • 1st Edition
      • Volume 703
      • September 10, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 3 0 4 2
      • eBook
        9 7 8 0 4 4 3 3 1 3 0 5 9
      Mononuclear Non-heme Iron Dependent Enzymes, Volume 703 focuses on methods for studying, characterizing, and leveraging the chemistry of mononuclear non-heme iron dependent enzymes. Chapters in this new release include Photoreduction for Rieske oxygenase chemistry, Insights into the Mechanisms of Rieske Oxygenases from Studying the Unproductive Activation of Dioxygen, Non-heme iron and 2-oxoglutarate enzymes catalyze cyclopropane and azacyclopropane formations, Obtaining precise metrics of substrate positioning in Fe(II)/2OG dependent enzymes using Hyperfine Sublevel Correlation Spectroscopy, Xe-pressurization studies for revealing substrate-entrance tunnels, and much more.Additional chapters cover A tale of two dehydrogenases involved in NADH recycling, Rieske oxygenases and/or their partner reductase proteins, Expression, assay and inhibition of 9-cis-epoxycarotenoi... dioxygenase (NCED) from Solanum lycopersicum and Zea mays, Biocatalysis and non-heme iron enzymes, In vitro analysis of the three-component Rieske oxygenase cumene dioxygenase from Pseudomonas fluorescens IP01, Structure and function of carbazole 1,9a-dioxygenase, Characterization of a Mononuclear Nonheme Iron-dependent Mono-oxygenase OzmD in Oxazinomycin Biosynthesis, and much more.

    • Advances in Applied Microbiology

      • 1st Edition
      • Volume 127
      • May 21, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 5 6 0
      • eBook
        9 7 8 0 4 4 3 2 9 5 5 7 7
      Advances in Applied Microbiology, Volume 127 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

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