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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • International Review of Cytology

      • 1st Edition
      • Volume 254
      • December 12, 2006
      • Kwang W. Jeon
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 6 3 8 5
      • eBook
        9 7 8 0 0 8 0 4 6 9 6 3 8
      International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

    • The Handbook of Metabonomics and Metabolomics

      • 1st Edition
      • December 11, 2006
      • John C. Lindon + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 2 8 4 1 4
      • eBook
        9 7 8 0 0 8 0 4 6 8 0 0 6
      Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

    • Cellular Transplantation

      • 1st Edition
      • December 11, 2006
      • Craig Halberstadt + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 6 9 4 1 5 7
      • eBook
        9 7 8 0 0 8 0 4 6 9 0 4 1
      There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices.

    • Annual Reports in Medicinal Chemistry

      • 1st Edition
      • Volume 41
      • December 8, 2006
      • English
      • Paperback
        9 7 8 0 1 2 0 4 0 5 4 1 1
      • eBook
        9 7 8 0 0 8 0 4 6 7 4 1 2
      Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

    • Fibrous Proteins: Amyloids, Prions and Beta Proteins

      • 1st Edition
      • Volume 73
      • December 8, 2006
      • John M. Squire + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 1 3 8 7
      • Hardback
        9 7 8 0 1 2 0 3 4 2 7 3 0
      • eBook
        9 7 8 0 0 8 0 4 6 8 9 5 2
      Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial. Fibrous proteins act as molecular scaffolds in cells providing the supporting structures of our skeletons, bones, tendons, cartilage, and skin. They define the mechanical properties of our internal hollow organs such as the intestines, heart, and blood vessels. This volume covers such topics as Beta-Structures in Fibrous Proteins; B-Silks: Enhancing and Controlling Aggregation; Beta-Rolls, Beta-Helices and Other Beta-Solenoid Proteins; Natural Triple B-Stranded Fibrous Folds; Structure, Function and Amyloidogenesis of Fungal Prions: Filament Polymorphism and Prion Variants; X-Ray Fiber and powder Diffraction of PRP Prion Peptides; From the Polymorphism of Amyloid Fibrils to Their Assembly Mechanism and Cytotoxicity; Structural Models of Amyloid-like Fibrils.

    • Progress in Heterocyclic Chemistry

      • 1st Edition
      • Volume 18
      • December 4, 2006
      • Gordon Gribble + 1 more
      • English
      • Paperback
        9 7 8 0 0 8 0 9 7 3 3 6 4
      • Hardback
        9 7 8 0 0 8 0 4 5 0 2 5 4
      • eBook
        9 7 8 0 0 8 0 4 6 7 5 7 3
      The eighteenth annual volume of Progress in Heterocyclic Chemistry, covers the literature published during 2005 on most of the important heterocyclic ring systems. This volume opens with two specialized reviews. The first, by Heui-Yeon Kim and Cheon-Gyu Cho covers 'The Diels-Alder cycloadditions of 3,5-dibromo-2-pyrone and its derivatives'. The second, by Jean-Luc Girardet and Stanley Lang discusses 'Recent developments in the chemistry of nucleosides'. The remaining chapters examine the 2005 literature on the common heterocycles in order of increasing ring size and the heteroatoms present. References are incorporated into the text using the journal codes adopted by Comprehensive Heterocyclic Chemistry, and are listed in full at the end of each chapter. Included in the index are systematic heterocyclic ring system names.

    • Molecular Biology and Genomics

      • 1st Edition
      • December 4, 2006
      • Cornel Mulhardt
      • English
      • Paperback
        9 7 8 0 1 2 0 8 8 5 4 6 6
      • eBook
        9 7 8 0 0 8 0 4 6 7 6 6 5
      Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.

    • Outcome Prediction in Cancer

      • 1st Edition
      • November 28, 2006
      • Azzam F.G. Taktak + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 2 8 5 5 1
      • eBook
        9 7 8 0 0 8 0 4 6 8 0 3 7
      This book is organized into 4 sections, each looking at the question of outcome prediction in cancer from a different angle. The first section describes the clinical problem and some of the predicaments that clinicians face in dealing with cancer. Amongst issues discussed in this section are the TNM staging, accepted methods for survival analysis and competing risks. The second section describes the biological and genetic markers and the rôle of bioinformatics. Understanding of the genetic and environmental basis of cancers will help in identifying high-risk populations and developing effective prevention and early detection strategies. The third section provides technical details of mathematical analysis behind survival prediction backed up by examples from various types of cancers. The fourth section describes a number of machine learning methods which have been applied to decision support in cancer. The final section describes how information is shared within the scientific and medical communities and with the general population using information technology and the World Wide Web.

    • Adult Stem Cells

      • 1st Edition
      • Volume 419
      • November 22, 2006
      • English
      • Hardback
        9 7 8 0 1 2 3 7 3 6 5 0 5
      • eBook
        9 7 8 0 0 8 0 4 6 9 1 6 4
      This is the second of three planned volumes in the Methods in Enzymology series on the topic of stem cells. This volume is a unique anthology of stem cell techniques focusing on adult stem cells, and written by experts from the top laboratories in the world. The contributors not only have hands-on experience in the field but often have developed the original approaches that they share with great attention to detail. The chapters provide a brief review of each field followed by a “cookbook” and handy illustrations. The collection of protocols includes the isolation and maintenance of stem cells from various species using “conventional” and novel methods, such as derivation of ES cells from single blastomeres, differentiation of stem cells into specific tissue types, isolation and maintenance of somatic stem cells, stem cell-specific techniques and approaches to tissue engineering using stem cell derivatives. The reader will find that some of the topics are covered by more than one group of authors and complement each other. Comprehensive step-by-step protocols and informative illustrations can be easily followed by even the least experienced researchers in the field, and allow the setup and troubleshooting of these state-of-the-art technologies in other laboratories.

    • Embryonic Stem Cells

      • 1st Edition
      • Volume 418
      • November 22, 2006
      • English
      • eBook
        9 7 8 0 0 8 0 4 7 1 1 2 9
      This is the first of three planned volumes in the Methods in Enzymology series on the topic of stem cells. This volume is a unique anthology of stem cell techniques written by experts from the top laboratories in the world. The contributors not only have hands-on experience in the field but often have developed the original approaches that they share with great attention to detail. The chapters provide a brief review of each field followed by a “cookbook” and handy illustrations. The collection of protocols includes the isolation and maintenance of stem cells from various species using “conventional” and novel methods, such as derivation of ES cells from single blastomeres, differentiation of stem cells into specific tissue types, isolation and maintenance of somatic stem cells, stem cell-specific techniques and approaches to tissue engineering using stem cell derivatives. The reader will find that some of the topics are covered by more than one group of authors and complement each other. Comprehensive step-by-step protocols and informative illustrations can be easily followed by even the least experienced researchers in the field, and allow the setup and troubleshooting of these state-of-the-art technologies in other laboratories.

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