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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • RNA Methodologies

      • 4th Edition
      • August 31, 2009
      • Robert E. Farrell Jr.
      • English
      • eBook
        9 7 8 0 0 8 0 8 8 4 9 5 0
      This is the fourth edition of the successful laboratory guide which has translated the rich story of riboneucleic acid for over fifteen years. RNA Methodologies 4e presents the latest collection of tested laboratory protocols for the isolation and characterization of eukaryotic and prokaryotic RNA with greater emphasis on transcript profiling, including quantification issues and elucidation of alternative transcription start sites. Collectively the chapters work together providing analysis with clear take-home lessons to assist researchers to understand RNA and to optimize time at the bench. The abundant use of flow charts, tables and graphs are especially helpful in the planning and implementation phases of a project and facilitate learning. 30% new material in this edition includes the addition of RNA isolation protocols including RNA isolation from tissue, expansion of PCR optimization analysis and RNA interference sections, the introduction of a new chapter dealing with the molecular biology of plants, and an expanded glossary.

    • Essential Zebrafish Methods: Cell and Developmental Biology

      • 1st Edition
      • August 27, 2009
      • Monte Westerfield + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 3 7 4 5 9 9 6
      • eBook
        9 7 8 0 0 8 0 9 2 3 4 3 7
      Due to its prolific reproduction and the external development of the transparent embryo, the zebrafish is the prime model for genetic and developmental studies, as well as research in genomics. While genetically distant from humans, nonetheless the vertebrate zebrafish has comparable organs and tissues that make it the model organism for study of vertebrate development.This book, one of two new volumes in the Reliable Lab Solutions series dealing with zebrafish, brings together a robust and up-to-date collection of time-tested methods presented by the world’s leading scientists. Culled from previously published chapters in Methods in Cell Biology and updated by the original authors where relevant, it provides a comprehensive collection of protocols describing the most widely used techniques relevant to the study of the cellular and developmental biology of zebrafish. The methods in this volume were hand-selected by the editors, whose goal was to a provide a handy and cost-effective collection of fail-safe methods, tips, and “tricks of the trade” to both experienced researchers and more junior members in the lab.

    • Bone Repair Biomaterials

      • 1st Edition
      • August 26, 2009
      • J. A. Planell
      • English
      • Hardback
        9 7 8 1 8 4 5 6 9 3 8 5 5
      • eBook
        9 7 8 1 8 4 5 6 9 6 6 1 0
      Bone repair is a fundamental part of the rapidly expanding medical care sector and has benefited from many recent technological developments. With an increasing number of technologies available, it is vital that the correct technique is selected for specific clinical procedures. This unique book will provide a comprehensive review of the materials science, engineering principles and recent advances in this important area.The first part of the book reviews the fundamentals of bone repair and regeneration. Chapters in the second part discuss the science and properties of biomaterials used for bone repair such as metals, ceramics, polymers and composites. The final section of the book discusses clinical applications and considerations with chapters on such topics as orthopaedic surgery, tissue engineering, implant retrieval and ethics of bone repair biomaterials.With its distinguished editors and team of international contributors, Bone repair biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia.

    • Molecular Diagnostics

      • 2nd Edition
      • August 21, 2009
      • George P. Patrinos + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 5 3 7 8
      • eBook
        9 7 8 0 0 8 0 9 2 3 1 8 5
      The 2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics and professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as academic institutions and hospital libraries.

    • Bone Cancer

      • 1st Edition
      • August 20, 2009
      • Dominique Heymann
      • English
      • eBook
        9 7 8 0 0 8 0 9 5 3 8 8 5
      The epidemiological and clinical importance of bone metastasis has long been recognized, but the past decade has seen an explosion in the fields of bone biology and bone cancer research. This period of time has been marked by a number of key discoveries that have led to the opening up of entirely new areas for investigation as well as new therapies which combine surgery and biological therapeutic approaches.Bone is a common site of cancer metastases - cancer cells commonly develop in bone and spread to other organ systems through the bloodstream. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on a patient's quality of life and are a main cause of patient mortality. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for the medical and cancer research communities. This book provides, all in one resource, the most recent data on bone cancer development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.

    • Foundations of Regenerative Medicine

      • 1st Edition
      • August 14, 2009
      • Anthony Atala
      • English
      • eBook
        9 7 8 0 1 2 3 7 8 5 6 2 6
      The interdisciplinary field of regenerative medicine holds the promise of repairing and replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Derived from the fields of tissue engineering, cell and developmental biology, biomaterials science, nanotechnology, physics, chemistry, physiology, molecular biology, biochemistry, bioengineering, and surgery, regenerative medicine is one of the most influential topics of biological research today.Derived from the successful Principles of Regenerative Medicine, this volume brings together the latest information on the advances in technology and medicine and the replacement of tissues and organs damaged by disease. Chapters focus on the fundamental principles of regenerative therapies that have crossover with a broad range of disciplines. From the molecular basis to therapeutic applications, this volume is an essential source for students, researchers, and technicians in tissue engineering, stem cells, nuclear transfer (therapeutic cloning), cell, tissue, and organ transplantation, nanotechnology, bioengineering, and medicine to gain a comprehensive understanding of the nature and prospects for this important field.

    • Fundamentals of Osteoporosis

      • 1st Edition
      • August 14, 2009
      • Robert Marcus + 3 more
      • English
      • eBook
        9 7 8 0 1 2 3 7 5 1 0 8 9
      Fundamentals of Osteoporosis offers a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work. Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, and histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery.

    • Advances in Planar Lipid Bilayers and Liposomes

      • 1st Edition
      • Volume 9
      • August 7, 2009
      • A. Leitmannova Liu
      • English
      • Paperback
        9 7 8 0 3 2 3 1 6 4 0 7 8
      • Hardback
        9 7 8 0 1 2 3 7 4 8 2 2 5
      • eBook
        9 7 8 0 0 8 0 8 8 8 6 5 1
      Advances in Planar Lipid Bilayers and Liposomes, Volume 9, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group. Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide.

    • G Protein-Coupled Receptors in Health and Disease, Part A

      • 1st Edition
      • Volume 88
      • August 5, 2009
      • English
      • eBook
        9 7 8 0 0 8 0 9 1 1 9 5 3
      G protein-coupled receptors (GPCRs) transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiological functions. It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly or indirectly. Because the current drugs target only a small portion of the GPCRs, opportunities for targeting the remaining GPCRs is enormous. This volume reviews the latest developments in this rapidly advancing field.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 102
      • July 30, 2009
      • George F. Vande Woude + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 1 6 3 6 0 6
      • Hardback
        9 7 8 0 1 2 3 7 4 4 3 7 1
      • eBook
        9 7 8 0 0 8 0 9 2 2 3 3 1
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including tumor dormancy, micro RNA, tumor angiogenesis, cancer in mouse models, liposome based chemo and autoimmunotherapy, signaling in angiogenesis, targeted cancer therapy, and regulatory t-cells.

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