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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Biomechatronics

      • 2nd Edition
      • September 4, 2024
      • Marko B. Popovic
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 8 6 2 1
      • eBook
        9 7 8 0 4 4 3 1 3 8 6 3 8
      Biomechatronics is rapidly becoming one of the most influential and innovative research directions defining the 21st century. The second edition Biomechatronics provides a complete and up-to-date account of this advanced subject at the university textbook level. This new edition introduces two new chapters – Animals Biomechatronics and Plants Biomechatronics – highlighting the importance of the rapidly growing world population and associated challenges with food production. Each chapter is co-authored by top experts led by Professor Marko B. Popovic, researcher and educator at the forefront of advancements in this fascinating field. Starting with an introduction to the historical background of Biomechatronics, this book covers recent breakthroughs in artificial organs and tissues, prosthetic limbs, neural interfaces, orthotic systems, wearable systems for physical augmentation, physical therapy and rehabilitation, robotic surgery, natural and synthetic actuators, sensors, and control systems. A number of practice prompts and solutions are provided at the end of the book. The second edition of Biomechatronics is a result of dedicated work of a team of more than 30 contributors from all across the globe including top researchers and educators in the United States (Popovic, Lamkin-Kennard, Herr, Sinyukov, Troy, Goodworth, Johnson, Kaipa, Onal, Bowers, Djuric, Fischer, Ji, Jovanovic, Luo, Padir, Tetreault), Japan (Tashiro, Iraminda, Ohta, Terasawa), Sweden (Boyraz), Turkey (Arslan, Karabulut, Ortes), Germany (Beckerle and Wiliwacher), New Zealand (Liarokapis), Switzerland (Dobrev), and Serbia (Lazarevic).

    • The Evolution of Immunotherapy Against Tumors

      • 1st Edition
      • August 27, 2024
      • Domenico Ribatti
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 7 9 8 2
      • eBook
        9 7 8 0 4 4 3 2 1 7 9 9 9
      The Evolution of Immunotherapy Against Tumors: An Historical Approach summarizes the literature concerning the development of the theory of immune surveillance against tumors. It discusses the evidence for and against this theory, along with the concept of immunoediting. Finally, current approaches in anti-tumor immunotherapy will be analyzed.The immune system plays a major role in the surveillance against tumors. To avoid attack from the immune system, tumor cells develop different strategies to escape immune surveillance. Evidence of immune surveillance comes from both animal models and clinical observations. Mice with a wide variety of immunodeficiencies have a high rate of tumor incidence and are more susceptible to transplanted or chemical carcinogen-induced tumors. Immunosuppressed patients have a high incidence of tumors. However, many patients develop cancer even in the presence of an apparently normal immune system. This indicates that tumor cells can escape immune surveillance.

    • Small Lungs and Obstructed Airways

      • 1st Edition
      • October 21, 2024
      • Peter Burney
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 9 2 2 2
      • eBook
        9 7 8 0 4 4 3 1 3 9 2 1 5
      Small Lungs and Obstructed Airways: Reassessing Chronic Obstructive Pulmonary Disease proposes an alternative perspective to current explanations for the distribution of chronic lung disease. The book considers the link between chronic respiratory disease and associated mortality with smaller lungs rather than obstructed airways and explores other factors contributing to poor lung health besides the current emphasis on the roles of air pollution, occupational exposures, and cardio-metabolic disease. It presents the findings of the Burden of Obstructive Lung Disease (BOLD) study, sharing new views on the prevalence of obstructive lung disease and risk factors across various global regions. Sections cover decreased lung function, including the prevalent views on the impact of both household and external air pollution, occupational exposure, and the prenatal and postnatal/childhood environment in the etiology of impaired lung function and COPD. The book then moves on to discussions on the impact poverty and nutrition has on lung health, sharing the findings of the BOLD study regarding its effect on lung function and risk of COPD in lower-income countries. The book closes with a chapter outlining the clinical and public health implications of the findings discussed in the book.

    • Genetics and Epigenetics of Genitourinary Diseases

      • 1st Edition
      • August 27, 2024
      • Seyed Mohammad Kazem Aghamir
      • English
      • Paperback
        9 7 8 0 4 4 3 2 7 3 0 2 5
      • eBook
        9 7 8 0 4 4 3 2 7 3 0 3 2
      Genetics and Epigenetics of Genitourinary Diseases aims to provide a comprehensive collection of data on genetics and epigenetics in almost all genitourinary diseases for researchers, clinicians, and graduate students.This book discusses several genetic and epigenetic changes like DNA methylation, mutations, single nucleotide polymorphisms, DNA rearrangements, chromosomal remodeling, microsatellite instability, and chromosomal instability (CIN) in genitourinary cancers.This book is split into 18 chapters, beginning with the importance of genetics and epigenetics in genitourinary diseases. It then goes on to cover the genetics and epigenetics of various diseases and tumors. Certain chapters present novel techniques of next-generation sequencing (NGS). Furthermore, RNA-Seq is discussed as a sequencing technique that uses NGS to reveal the presence and quantity of RNA in a biological sample.This book is a valuable resource for researchers, practitioners, and students in genetics and epigenetics who want to broaden their understanding of the field.

    • Antioxidant Methods

      • 1st Edition
      • April 14, 2024
      • Francisco Avelino
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 5 9 1 9
      • eBook
        9 7 8 0 4 4 3 2 1 5 9 0 2
      Antioxidant Methods: A Guideline for Understanding and Determining AntioxidantCapacity summarizes the importance of antioxidants as a class of compounds withinnumerous areas of science and technology. The chapters elucidate diverse methodologiesfor assessing the antioxidant capacity of an antioxidant, while also exploring the correlationbetween its structural attributes and overall performance. Chapters include descriptions ofprotocols used to measure antioxidant capacity by different methods, highlighting experimentalsteps, bottlenecks, expected outcomes, advantages, limitations, and more.This is the perfect reference for biomedical science researchers looking for the right methodfor determining antioxidant capacity through the structure and functionalities of the compound,as well as the mechanisms involved in the antioxidant action.

    • Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies

      • 1st Edition
      • June 25, 2024
      • Wendy Fantl
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 1 3 3
      • eBook
        9 7 8 0 1 2 8 2 2 2 1 4 0
      Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies: ApplicationsHealthy tissues and organs rely on the precise coordination of diverse cell types, each responding to external and internal signals. Disease disrupts this coordination. Since proteins drive cellular function, analyzing their abundance and activation states in single cells helps identify key cell populations in health and disease. Bulk protein analyses mask critical differences between individual cells. Additionally, the arrangement of cells into neighborhoods through cell-cell interactions is essential for tissue function. Over the last decade, single-cell proteomic phenotyping combined with positional information has become crucial for understanding biology in health and disease. This has led to the development of multiple technology platforms, profoundly impacting fields including developmental biology, cancer biology, immunology, neuroscience, and drug discovery. This book focuses on the application of single-cell multiplex proteomic platforms to various biological systems. These platforms have proved to be essential in biomedical research, advancing our understanding of complex biological systems at the cellular level. Compelling studies where authors use these technologies to answer previously unanswerable questions are featured. Exploring this "Uncharted Biology" opens new avenues for scientific inquiry and clinical translation, covering areas including oncology, immunology, metabolomics, stem cell research, preclinical models, and translational research. The initial chapters discuss incorporating these technologies into core facilities and consortia, providing access for multiple users and integrating datasets from other omics technologies. The following chapters cover applications in diverse areas such as muscle stem cell function in skeletal muscle regeneration, metabolic regulome profiling, translational studies, developing predictive biomarkers for patients receiving immune checkpoint inhibitors, and pre-clinical studies of lung cancer. These applications demonstrate how advanced single cell proteomic technologies are reshaping our understanding of complex biological systems and enhancing clinical translation. Revealing Uncharted Biology with Single Cell Multiplex Proteomic Technologies: Applications highlights the transformative benefits of single-cell proteomics, offering insights into cellular mechanisms underlying health and disease and inspiring further exploration into "Uncharted Biology." It is an essential resource for researchers, clinicians, and students aiming to advance biomedical science and improve therapeutic outcomes.

    • Comprehensive Hematology and Stem Cell Research

      • 1st Edition
      • August 14, 2024
      • Nima Rezaei
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 7 1 7 2
      • eBook
        9 7 8 0 4 4 3 1 5 7 1 8 9
      **2025 PROSE Award Category Winner in Clinical Medicine**Comprehens... Hematology and Stem Cell Research is the first major reference to cover both stem cell research and therapy as well as the range of hematological disorders they are currently used to treat and may potentially be able to treat in the future. This five volume set includes fundamentals, such as the underlying mechanisms of the blood and immune system, highlighting blood disorders and cancers of the blood, including lymphoma, leukemia, and myeloma. Other sections cover stem cell research and therapy, from harvesting stem cells to their utilization in cancer treatments.Finally, the work looks to the future and explores newer stem cell research that may lead to future treatments. This book is an excellent resource for students at the graduate and post-graduate levels, academics, and researchers in the fields hematology, immunology and oncology.

    • Childhood Obesity

      • 1st Edition
      • September 13, 2024
      • Luis Moreno
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 9 7 5 7
      • eBook
        9 7 8 0 4 4 3 2 1 9 7 4 0
      Childhood Obesity: From Basic Knowledge to Effective Prevention brings together field experts, taking a multifactorial approach to understand the scope and various causes of the issue and offer the latest in treatment and prevention strategies and resources. Beginning with basic concepts and definitions, chapters progress to cover worldwide prevalence and trends, genetic and epigenetic origins, metabolic programming, and neuroendocrine control of appetite and satiety. Further, this book examines social determinants and lifestyle behaviors contributing to risk factors as well as complications associated with childhood obesity.Final chapters discuss multidisciplinary treatment, strategies for prevention, and current worldwide policies aimed to address obesity in children. This fundamental reference is a vital resource for both researchers and practicing clinicians in pediatric medicine.

    • Advances in Cytometry: Applications

      • 1st Edition
      • Volume 186
      • April 23, 2024
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 4 1 9 4
      • eBook
        9 7 8 0 3 2 3 9 9 4 2 0 0
      Advances in Cytometry: Applications, Volume 176 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

    • Deep Learning in Genetics and Genomics

      • 1st Edition
      • November 28, 2024
      • Khalid Raza
      • English
      • Paperback
        9 7 8 0 4 4 3 2 7 5 2 3 4
      • eBook
        9 7 8 0 4 4 3 2 7 5 2 4 1
      Deep Learning in Genetics and Genomics: Vol. 2 (Advanced Applications) delves into the Deep Learning methods and their applications in various fields of studies, including genetics and genomics, bioinformatics, health informatics and medical informatics generating the momentum of today's developments in the field. In 25 chapters this title covers advanced applications in the field which includes deep learning in predictive medicines), analysis of genetic and clinical features, transcriptomics and gene expression patterns analysis, clinical decision support in genetic diagnostics, deep learning in personalised genomics and gene editing, and understanding genetic discoveries through Explainable AI. Further, it also covers various deep learning-based case studies, making this book a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning based approaches. This volume is not only a valuable resource for health educators, clinicians, and healthcare professionals but also to graduate students of genetics, genomics, biology, biostatistics, biomedical sciences, bioinformatics, and interdisciplinary sciences.

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