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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Handbook of Mutagenicity Test Procedures

      • 2nd Edition
      • December 2, 2012
      • B.J. Kilbey + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 7 1 9 2
      • eBook
        9 7 8 0 4 4 4 6 0 0 9 8 1
      The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.

    • Idiotypes

      • 1st Edition
      • December 2, 2012
      • Morris Reichin
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 3 3 6 1
      • eBook
        9 7 8 0 3 2 3 1 5 1 3 7 5
      Idiotypes documents the proceedings of an International Conference on Idiotypes held in Oklahoma City, Oklahoma, at the Oklahoma Medical Research Foundation, October 20-23, 1985. The aims of the conference were to gather active investigators in the study of idiotypes; to assess progress in the field; and to explore directions for future research. The papers presented at the conference cover a wide range of subjects. Several papers deal with defining protein and DNA sequences which determine idiotypes. Evidence points to germ line genes encoding the V region structures which underlie idiotypy. Another subtheme which concerns several contributions is the occurrence of dominant idiotypes in induced immune responses (e.g., arsonate and lysozyme) and autoimmunity (e.g., thyroglobulin and rheumatoid factors). The presence of such dominant idiotypes is discussed from several viewpoints, but the recurrent theme is that such dominance is a manifestation of a selection process inherent in the idiotypic network. Two papers deal with idiotypic structures in T cells: on the one hand, identifying idiotypes on T helper cells and, on the other, I-J and Iat related structures which tightly govern cellular interactions in the evolution of an immune response. Network interactions through autoanti-idiotypic responses are shown to be associated with the effects on the specificity of both induced and naturally occurring immune responses. Autoanti-idiotypic responses are also shown to be correlated with the regulation of the anti-DNA response in human systemic lupus erythematosus. These data pointed to a role of the idiotype network in immune regulation.

    • Photosynthesis, Photorespiration, And Plant Productivity

      • 1st Edition
      • December 2, 2012
      • Israel Zelitch
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 6 0 8 9
      • eBook
        9 7 8 0 3 2 3 1 5 4 1 1 6
      Photosynthesis, Photorespiration, and Plant Productivity provides a basis for understanding the main factors concerned with regulating plant productivity in plant communities. The book describes photosynthesis and other processes that affect the productivity of plants from the standpoint of enzyme chemistry, chloroplasts, leaf cells, and single leaves. Comprised of nine chapters, the book covers the biochemical and photochemical aspects of photosynthesis; respiration associated with photosynthetic tissues; and photosynthesis and plant productivity in single leaves and in stands. It provides illustrated and diagrammatic discussion and presents the concepts in outlined form to help readers understand the concepts efficiently. Moreover, this book explores the rates of enzymatic reactions and the detailed structure and function of chloroplasts and other organelles and their variability. It explains the mechanism of photosynthetic electron transport and phosphorylation and the importance of diffusive resistances to carbon dioxide assimilation, especially the role of stomata. It also discusses the importance of dark respiration in diminishing productivity; the differences in net photosynthesis that occur between many species and varieties; and the influence of climate to photosynthetic reactions. The book is an excellent reference for teachers, as well as undergraduate and graduate students in biology, plant physiology, and agriculture. Research professionals working on the disciplines of plant production and food supply will also find this book invaluable.

    • Neurobiology of Social Communication In Primates

      • 1st Edition
      • December 2, 2012
      • Horest Steklis
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 7 1 4 7
      • eBook
        9 7 8 0 3 2 3 1 5 5 2 0 5
      Neurobiology of Social Communication in Primates: An Evolutionary Perspective presents evidence on the neural basis of communicative behavior in primates, reevaluating the relationship between human language and animal communication in view of the linguistic abilities of chimpanzees. This book consists of 10 chapters. Chapter 1 discusses some of the persistent problems in evolutionary neurobiology of primate communication. The effects of brain lesions and stimulation on vocalization in New and Old World monkeys, relation between species differences in peripheral vocal structures and species contrasts in vocal performance, and anatomy and physiology of the nonhuman primate auditory system are reviewed in Chapters 2 to 4. Chapters 5 to 7 examine the effects of electrical brain stimulation on human verbal communication and facial expression, clinical data pertaining to language pathologies, and neural mechanisms of manual and oral control. The last three chapters summarize the materials presented in earlier chapters. This publication is recommended for neuroscientists, behavioral biologists, neurologists, psychiatrists, and students interested in the evolutionary heritage of human speech and language.

    • Brain Messengers and the Pituitary

      • 1st Edition
      • December 2, 2012
      • Eugenio Muller
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 7 7 9
      • eBook
        9 7 8 0 3 2 3 1 4 2 9 2 2
      Brain Messengers and the Pituitary discusses the significant advances in neurotransmission and in understanding the physiology and pathophysiology of neuroendocrine control. This book is organized into seven chapters and begins with a discussion on the main biochemical and electrophysiological mechanisms underlying synaptic communication and the cotransmission and receptor plasticity. The following chapters describe the topographical localization and function of classical neurotransmitter and neuropeptide neurons. This book then presents the evidence on pituitary function control by the brain through specific hypophysiotropic regulatory hormones in relation to the secretion of adrenocorticotropic hormone and pro-opiomelanocortin... peptides, growth hormone, gonadotropins, prolactin, and thyroid-stimulating hormone. A chapter focuses on the neuroendocrine effects of an increasing number of neuropeptides. This text further deals with the role of pituitary gland as the target of central nervous system-derived and peripheral hormonal influences. The concluding chapters look into the experimental evidence linking brain neurotransmitters to the secretion of hypothalamic hormones and to anterior pituitary hormones or to neuroendocrine feedback regulation. These chapters also explore the evidence for neurotransmitter-neu... dysfunction as an etiology for specific neuroendocrine disorders and the potential of the neuropharmacologic approach to the diagnosis and therapy. Clinical neuroendocrinologist... and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.

    • Drugs and the Cell Cycle

      • 1st Edition
      • December 2, 2012
      • A Zimmerman
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 6 9 5 9
      • Hardback
        9 7 8 0 1 2 7 8 1 2 6 0 1
      • eBook
        9 7 8 0 3 2 3 1 5 5 0 1 4
      Drugs and the Cell Cycle provides an introduction to fundamental principles and studies on the mechanisms of drug action on proliferating cells. The book is intended to reduce the time lag between observation and practical application. Comprised of 10 chapters, the book describes the plant alkaloids, alkylating agents, mercurials, adrenergic agents, radiomimetics, narcotics, hallucinogens, mitogens, hepatotoxins, antiobiotics, and antimetabolites of various types. The text also emphasizes the drugs used in cancer chemotherapy, and the in vitro and in vivo cell systems of bacteria, protozoa, sea urchins, and mammals. The concepts are presented with comprehensive illustrations and tables to help readers obtain more efficient understanding and learning. The information and concepts presented in this volume will be of great interest to scientists and students in many disciplines, including physiology, pharmacology, and oncology, as well as cellular, molecular, and developmental biology. The book will also fill the gap between drug experimental observations and their potential relevance to man.

    • Biology of Halophytes

      • 1st Edition
      • December 2, 2012
      • Yoav Waisel
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 3 5 7 6
      • Hardback
        9 7 8 0 1 2 7 3 0 8 5 0 0
      • eBook
        9 7 8 0 3 2 3 1 5 1 5 8 0
      Biology of Halophytes is a monograph on the biological aspects of halophytes and their behavior under saline conditions. It explores the physioecological characteristics of halophytes, such as reproduction, growth, metabolism, water relations, mineral nutrition, salt transport, salt secretion, and salt resistance. It also provides ecological information on higher marine plants, particularly submerged angiosperms, mangroves, and high coast plants. Organized into 16 chapters, this volume begins with an overview of sources of salinity and the development and nature of salines and salt-affected soils. It proceeds with a discussion of the classification of halophytes, their mutual relationships, distribution, and sociology. It also summarizes autecological information on some terrestrial halophytes and introduces the reader to the formative effects of salinity, interrelationships between plants and spatial distribution within the community, ion transport and mineral nutrition, and regulation of salt content of shoots, before concluding with a short review on ecotypic differentiation in halophytes. This book will be a valuable resource for advanced students, as well as teachers of plant and environmental sciences.

    • High Pressure Liquid Chromatography

      • 1st Edition
      • December 2, 2012
      • Phyllis Brown
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 6 8 6 5
      • eBook
        9 7 8 0 3 2 3 1 6 0 0 5 6
      High Pressure Liquid Chromatography: Biochemical and Biomedical Applications covers basic information on high pressure liquid chromatography in a simple and concise manner. It describes high pressure liquid chromatography, encompassing the method’s history and advantages. The book explains the instrumentations, experimental methods, peak identification, quantitation, and applications of high pressure liquid chromatography. It also discusses the pitfalls likely to be encountered in utilizing such method. This reference serves as an introductory book for all those who are unfamiliar with high pressure liquid chromatography. This book can also be used as a reference for those who are currently using the technique. It can also aid in promoting the use of high pressure liquid chromatography in all biochemical and biomedical researches.

    • Extrachromosomal DNA

      • 1st Edition
      • December 2, 2012
      • Donald Cummings
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 2 1 9 0
      • eBook
        9 7 8 0 3 2 3 1 4 5 3 5 0
      Extrachromosomal DNA contains the proceedings of the 1979 ICN-UCLA Symposia on Molecular and Cellular Biology held in Keystone, Colorado. Contributors focus on extrachromosomal DNA, paying particular attention to the biogenesis of yeast mitochondria. They discuss topics based on the premise that the diversity and complexity of primitive mitochondrial and perhaps chloroplast DNA structure and replication have more in common with many viral systems than with either prokaryotic or eukaryotic systems. This is especially striking in the case of so-called split genes. This book is organized into nine sections encompassing 34 chapters and begins with an overview of extranuclear genetics and the evolution and regulation of mitochondrial biogenesis. The following chapters explore the genetic capacity and structure of chloroplast DNA, viral replication and function, and viral nucleic acids. The possibility of isolating mutants in some intervening sequences and analyzing their effect in loci of known genetic function is demonstrated. The reader is also introduced to the analysis of intervening genes and its importance in yeast mitochondria, as well as the sequencing of a variety of genes of known function. This book also considers the organization, function, and expression of extrachromosomal DNA in yeast, along with the genetics and biogenesis of mitochondrial DNA from higher eukaryotes, and then concludes with a description of the biological and structural characteristics of kinetoplast and Podospora mitochondrial DNA. This book will be of interest to researchers involved in mitochondrial, chloroplast, plasmid, and viral DNA function and replication.

    • The Plasma Proteins V5

      • 2nd Edition
      • December 2, 2012
      • Frank Putnam
      • English
      • Paperback
        9 7 8 0 1 2 3 9 4 1 8 2 4
      • eBook
        9 7 8 0 3 2 3 1 6 1 7 4 9
      The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume V explores the contribution of molecular biology and gene cloning approaches to the advancement of plasma protein structure, function, and genomic organization studies. This volume is composed of five chapters and begins with a discussion on the DNA sequences and chromosomal location of plasma protein genes, specifically the cloning and sequencing of immunoglobulin genes. These topics are followed by a discussion on the advances in relation to discovered genetic variants present either as normal phenotypes or in dyslipoproteinemic states associated with cardiovascular disease. A chapter highlights the application of molecular biology techniques to the study of gene structure and the translational and maturation steps of every major plasma apolipoprotein. Another chapter emphasizes the unique features of protein structure and the conformational changes that characterize the assembly of macromolecular complexes in plasma and on cell surfaces. The concluding chapter provides a comprehensive review of the integration of molecular biology, physiology, and pathology of plasma proteins and their response in inflammation. This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.

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