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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Cell-based Cancer Immunotherapy

      • 1st Edition
      • Volume 183
      • March 5, 2024
      • English
      Cell-based Cancer Immunotherapy, Volume 183 provides the latest progress concerning research on anticancer cellular immunotherapies and their immunological, translation, or clinical aspects. Topics covered in this volume include Methods behind clinical DC vaccine products against glioblastoma, Fully closed and automated isolation of natural blood dendritic cells for cancer immunotherapy, Methods behind Oncolytic virus-based DC vaccines in cancer: towards a multiphase combined treatment strategy for Glioblastoma (GBM) patients, Identification of TCR repertoire patterns linked with anti-cancer immunotherapy, Training of epitope-TCR prediction models with healthy donor-derived cancer-specific T cells, Methods behind neoantigen predictions for anticancer vaccines, Methods behind CD137L-DC-EBV-VAX anticancer vaccine, and much more. Additional sections cover Gold Standard Assessment of Immunogenic Cell Death Induced by Photodynamic Therapy: From In Vitro to Tumor Mouse Models and Anti-Cancer Vaccination Strategies, Methods behind TCR analyses for colorectal cancer-associated TILs, The use of xCELLigence, Incucyte, and/or Cr/LDH/maker-release assays, Humanized mouse models for anti-cancer therapy, In vitro re-challenge of CAR T cells, Methods behind adoptively transferred tumor draining lymphocytes​ for anticancer immunotherapy, and A murine glioblastoma platform to test cellular therapies with the standard of care.

    • Safe Major Hepatectomy after Preoperative Liver Regeneration

      • 1st Edition
      • January 16, 2024
      • Yoshihiro Sakamoto + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 6 9 8 3
      • eBook
        9 7 8 0 3 2 3 9 9 6 9 9 0
      Safe Major Hepatectomy After Preoperative Liver Regeneration: Preoperative PVE, Two-Stage Hepatectomy, ALPPS and Hepatic Vein Deprivation provides both history and recent topics of major hepatectomy after liver regeneration—as well as the basic background of liver regeneration—allowin... liver surgeons, general surgeons, and hepatologists to increase the safety of major hepatectomy in patients suffering from advanced liver disease. This reference provides importance guidance to cutting edge topics, including the molecular mechanism of liver regeneration after preoperative portal vein embolization (PVE), two-stage hepatectomy, associating liver partition and portal vein occlusion for staged hepatectomy (ALPPS) and results of hepatic vein occlusion.The mortality rate after major hepatectomies is high worldwide and there is a need to establish a strategy for safe major hepatectomies, and hepatectomy after preoperative liver regeneration is a key process to prevent posthepatectomy liver failure (PHLF).

    • Protocols in Biochemistry and Clinical Biochemistry

      • 2nd Edition
      • October 16, 2024
      • Buddhi Prakash Jain + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 9 4 5 1
      • eBook
        9 7 8 0 4 4 3 1 3 9 4 6 8
      Protocols in Biochemistry and Clinical Biochemistry, second edition, offers clear, applied instruction in fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose, and cholesterol levels, among other diagnostics. Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods, and troubleshooting, all to support a range of study types and clinical diagnostics. This fully revised edition has been expanded and enriched to feature 100 protocols, as well as chapter key term definitions and worked examples. All-new protocols added to this edition include identification of lipids by TLC, lipid per oxidation measurement by thiobarbituric acid assays, determination of serum amylase, catalase activity assay, superoxide dismutase assay, qualitative analysis of plant secondary metabolites, qualitative analysis of photochemicals, quantitative estimation of secondary metabolites, estimation of chlorophyll contents, and starch determination, among others. Each protocol is written to help researchers and clinicians easily reproduce lab methods and ensure accurate test results.

    • Phylogenomics

      • 1st Edition
      • May 17, 2024
      • Igor Mokrousov + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 8 8 6 4
      • eBook
        9 7 8 0 3 2 3 9 1 3 0 9 6
      Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

    • Non-Traumatic Acute Surgical Problems

      • 1st Edition
      • September 16, 2024
      • Constantine P. Spanos
      • English
      • Paperback
        9 7 8 0 4 4 3 3 3 8 3 3 5
      • eBook
        9 7 8 0 4 4 3 3 3 8 3 4 2
      Non-Traumatic Acute Surgical Problems: An Infographic Guide is curated to offer a comprehensive understanding of acute surgical challenges, excluding trauma. Tailored specifically for medical students navigating their surgical rotations and seasoned instructors in the field, this guide serves as an indispensable resource. Each chapter serves as a path through the intricacies of acute surgical conditions with clarity and depth. Contents provide insight into the complexities of acute cholecystopathy, appendicitis, and acute pancreatitis, providing invaluable insights into diagnosis and sophisticated management strategies. This book navigates through the labyrinth of gastrointestinal bleeding scenarios, encompassing upper, lower, and variceal bleeding, as well as formidable challenges like caustic ingestion and esophageal perforation. Contents further cover vascular emergencies, unraveling the mysteries of aortic dissection, peripheral arterial embolism, and hypercoagulability, while mastering essential principles for timely and effective intervention. Coverage includes the subtleties of urological emergencies such as renal colic, pyelonephritis, and testicular torsion, alongside gynecological conditions including ectopic pregnancy and pelvic inflammatory disease.With a wealth of information, thoughtfully structured in an accessible format, this book not only empowers but emboldens its readers. Equipped with knowledge, insight, and confidence, individuals traversing the realm of acute surgical problems are fortified to navigate the challenges of real-world clinical settings with unwavering competence and assurance.

    • Targeting Signaling Pathways in Solid Tumors Part B

      • 1st Edition
      • Volume 386
      • May 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 5 4 8 1
      • eBook
        9 7 8 0 4 4 3 2 3 5 4 9 8
      Targetting Signaling Pathways in Solid tumour Part B, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

    • Magnetic Tweezers for the Study of Protein Structure and Function

      • 1st Edition
      • Volume 694
      • March 14, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 2 2 2 9 0
      • eBook
        9 7 8 0 4 4 3 2 2 2 3 0 6
      Magnetic Tweezers for the Study of Protein Structure and Function, Volume 694 in the Methods in Enzymology serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Single membrane protein tethering for magnetic tweezer experiments, Membrane protein folding studies using a robust magnetic tweezer method, Magnetic tweezers in cell mechanics, and more.

    • Animal Models of Disease Part A

      • 1st Edition
      • Volume 185
      • March 29, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 2 2 3 8 2
      • eBook
        9 7 8 0 4 4 3 2 2 2 3 9 9
      Animal Models of Disease, Part A, Volume 185 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including New mouse model to study aneurysm development, Mouse Model of Secondary Cystic Echinococcosis, Modelling childhood cancer in Drosophila, Analysis of immunohistomorpholog... changes in the colonic mucosa in a high-saturated fat and high-cholesterol fed streptozotocin/nicot... diabetic rat model, Establishment of an orthotopic Glioblastoma mouse model for preclinical studies, Lateral Fluid Percussion Injury as a Model for Traumatic Brain Injury, Ovarian and colorectal peritoneal carcinomatosis in mouse models, and more.Other chapters cover Genetically engineered mouse model of hepatocellular carcinoma, Radiotherapy protocol in cancer mouse models, Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation, Methodology for the induction of myocardial infarction and cardiac function evaluation, Behavioral assessment of fine socio-sexual olfactory cues detection in a mouse model of neurodegeneration, Heat shock and thermotolerance in Caenorhabditis elegans: an overview of laboratory techniques, and Using the model cestode Taenia crassiceps for the study of cysticercosis.

    • Advances in Biomembranes and Lipid Self-Assembly

      • 1st Edition
      • Volume 39
      • June 20, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 6 3 4 5
      • eBook
        9 7 8 0 4 4 3 2 9 6 3 5 2
      Advances in Biomembranes and Lipid Self-Assembly, Volume 39 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 119
      • March 21, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 8 0 5
      • eBook
        9 7 8 0 4 4 3 2 9 5 8 1 2
      Advances in Clinical Chemistry, Volume 119, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. Topics covered in this new release include Advances in Endotoxin Analysis, SARS-CoV-2 detection and surveillance, Osteopontin in Cancer, Gastrointestinal Hormones: History, Biology, and Measurement, Natriuretic Peptide Testing Strategies in Heart Failure: a 2023 Update, and Defining Allowable Total Error Limits in the Clinical Laboratory.

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