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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Cell Biology and Immunology of Leukocyte Function

      • 1st Edition
      • December 2, 2012
      • Efraim Racker
      • English
      • Hardback
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      Cell Biology and Immunology of Leukocyte Function is a collection of papers presented at the 12th International Leukocyte Culture Conference, held in Beersheba, Israel on June 1978. This book is organized into seven parts encompassing 111 chapters. The contributors cover the different aspects of cell biology and immunology and the unique leukocyte function. Part I describes the mechanism of lymphocyte activation, the structure and function of the plasma membrane, and the macromolecular synthesis during lymphocyte activation. This part also deals with the interaction of lymphocytes with mitogenic lectins, the comparison of the mitogenic and nonmitogenic lectin binding, and the role of macrophages in the response of lymphocytes to lectins. Part II explores the thymic factors and the development of characteristic markers, antigens, and receptors. This part particularly emphasizes lymphocyte differentiation. Parts III and IV examine the genetic control and intercellular interactions involved in leukocyte function and the parameters of the immune response under in vitro conditions. Chapters on cytotoxicity, the mechanisms of phagocytic killing, autoimmunity, and the responses of leukocytes to tumor cells are included in these parts. Part V discusses the interactions of viruses and leukocytes and provides data on the physical mapping and analysis of sarcoma and leukemia viruses, while Part VI considers the application of leukocyte culture to problems of clinical medicine. Part VII involves the study of radiation effects, with an emphasis on the application of total lymphoid irradiation to the induction of transplantation tolerance. This part also looks into the role of the DNA repair process. Cell biologists, immunologists, and biomedical scientists and researchers will greatly benefit from this book.
    • Advances in Physiology, Biochemistry, and Function V4

      • 1st Edition
      • December 2, 2012
      • A.D. Johnson
      • English
      • Paperback
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      • Hardback
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      The Testis: Advances in Physiology, Biochemistry, and Function, Volume IV, provides an overview of the state of knowledge in the physiology, biochemistry, and function of the testis. This volume updates those areas of greatest research activity and introduces in a more complete manner those topics which have developed as subject areas in themselves. It includes a chapter on testicular steroidogenesis, which updates and expands the chapter appearing in Volume II. In addition, chapters on the role of FSH in the testis, the specialized (largely endocrine) functions of the Sertoli cells, and the entire account of the tubular hormone inhibin have all been extensions of material in the original chapter on testicular endocrinology. Similarly, separate chapters on blood flow in the testis, fluid secretion, and the blood-testis barrier all report data on subjects largely unsuspected when Volumes I-III were published. Neither the first three volumes nor is the present one intended primarily for the nonprofessional biologist or the popular reader. The coverage should be most useful and informative to professional biologists. It is anticipated that this volume will also be of interest to advanced students of animal biology as an authoritative, comprehensive, and convenient review of significant recent information concerning the testis.
    • Growth, Nutrition, and Metabolism of Cells In Culture V2

      • 1st Edition
      • December 2, 2012
      • George Rothblat
      • English
      • Paperback
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      Growth, Nutrition, and Metabolism of Cells in Culture, Volume 2, summarizes the state of knowledge of the growth, nutrition, and metabolism of various types of cell cultures. The chapters are both detailed and comprehensive enough for the specialist and broad enough to provide a general background for the nonspecialist. The present volume deals with specialized mammalian, plant, and invertebrate cell systems and techniques. The book begins by tracing the history of the development of tissue culture. This is followed by separate chapters on the use of perfusion systems in cell and tissue culture; and the cultivation of muscle tissue, nerve tissue, and hematopoietic cells. Subsequent chapters discuss the use of cell culture to study mechanisms of hormone action; the cultivation of mammalian embryos; cultivation of cells from poikilothermie vertebrates; and the cultivation of arthropod cells and plant cells. This book will be valuable resource for investigators who routinely use cell culture techniques, as well as students and individuals in associated areas of cell and molecular biology.
    • Molecular Mechanisms of Protein Biosynthesis

      • 1st Edition
      • December 2, 2012
      • Herbert Weissbach
      • English
      • Paperback
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      • eBook
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      Molecular Mechanisms of Protein Biosynthesis is a collection of papers dealing with cell-free systems at the molecular level, including transfer RNA; the initiation, elongation, and termination processes; ribosome structure and function; mRNA translation; and DNA-directed in vitro protein synthesis. A couple of papers review tRNA, aminoacyl-tRNA synthetases, and aspects of ribosome structure. One paper discusses affinity labeling in the study of binding and catalytic sites of large complex and heterogeneous systems such as the ribosome. The investigator should be aware of the chemically reactive or photoactivatible analogue reacting specifically with one or more ribosomal components. This reaction should be determined if it is dependent on the correct binding of the affinity label at the functional site. Another paper describes the series of reactions in protein synthesis as the process by which the ribosome moves relative to the messenger RNA. Other papers discuss messenger RNA and its translation, DNA-dependent cell-free protein synthesis, as well as the genetics of the translational apparatus. The collection will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.
    • Prostaglandin synthesis

      • 1st Edition
      • December 2, 2012
      • Jasjit Bindra
      • English
      • Paperback
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      Prostaglandin Synthesis reviews the developments in the preparation and isolation of prostaglandins by synthesis, with emphasis on the more promising and significant approaches. It includes a nomenclature of prostaglandins and considers prostaglandin analogs as well as their structure-activity relationships, prostaglandin interconversions, isomeric prostaglandins, and deoxyprostaglandins. Organized into 21 chapters, this book begins with an overview of prostaglandin biosynthesis and the potential clinical utility of prostaglandins. It then discusses the discovery of prostaglandins and the isolation of prostaglandins E and F, format for structural presentation of prostaglandins, closure of the cyclopentane ring from acyclic precursors, and conjugate addition of organometallic derivatives to alpha-substituted cyclopentenones. It explains the cyclohexane and bicyclohexane precursors, Corey's synthesis of bicyclohexane precursors, bicyclooctane and bicyclononane precursors, and approaches to synthesis of A, B, C, and D prostaglandins. This book is a valuable resource for biochemists and others working in the field of prostaglandin biosynthesis.
    • Basic sleep Mechanisms

      • 1st Edition
      • December 2, 2012
      • Olga Petre-Quadens
      • English
      • Paperback
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      Basic Sleep Mechanisms is a collection of studies about the different mechanisms that facilitate the process of sleep. The studies, despite being made by experts of different subspecialties, are more purposed for general interest. The book is divided into four parts. Part I covers the concepts under the neurophysiological mechanisms of sleep, such as the sleep-wake cycle, pontine stimulations of sleep, and the role of different parts of the nervous system in sleep. Part II includes topics under the neurochemical aspects of sleep and the role of monoaminergic neurons in it. Part III discusses the different three states of the adult human body, the direction in its research, and its psychological aspect. Part IV explains the developmental aspects of sleep, especially in infants and children. The text is recommended for neurologists, doctors, and psychologists who want to know more about the study or to conduct their own study about sleep, the principles behind it, and its development.
    • The Hormones V4

      • 1st Edition
      • December 2, 2012
      • Mohhamad Reza Kiani
      • English
      • Paperback
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      The Hormones: Physiology, Chemistry and Applications, Volume IV covers the advances in understanding the nature and function of plant and non-mammalian animal hormones. This volume is divided into 11 chapters, and begins with an examination of the major characteristics of auxins, including the diversity of its action, chemical control, and systematic patterns. The subsequent chapters explore the chemistry and physiology of neurohormones and their role in insect growth. A chapter highlights the control of color of hormones and the actions of 5-hydroxytryptamine. The remaining chapters are devoted to the occurrence, physiological role, biochemistry, mode of action, metabolism, and biosynthesis of other hormones, such as gastrointestinal hormones, catecholamines, insulin, and glucagon. These chapters deal also with the general principles and application of immunoassay of protein hormones. Endocrinologists, physiologists, biochemists, and hormone researchers will find this book invaluable.
    • Biology of Memory

      • 1st Edition
      • December 2, 2012
      • Karl Pribram
      • English
      • Paperback
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      Biology of Memory investigates the biological basis of memory and covers topics ranging from short- and long-term post-perceptual memory to memory storage processes, memory microstructures, chemical transfer, and neuronal plasticity. The activity of neuronal networks in the thalamus of the monkey is also examined, along with integrative functions of the thalamocortical visual system of the cat. Comprised of 20 chapters, this book begins with an overview of the mechanisms that inhibit or interfere with short- and long-term memory, followed by a discussion on different retrieval mechanisms for short- and long-term memory. The reader is then introduced to the role of short- and long-term memory in the formation, retention, and utilization of associations, together with the link between memory and the medial temporal regions of the brain. Subsequent chapters focus on anatomical and chemical changes in the brain during primary learning; cellular models of learning and cellular mechanisms of plasticity in Aplysia; trace phenomena in single neurons of hippocampus and mammiliary bodies; and plasticity in single units in the mammalian brain. The book concludes with a description of Occam (Omnium-Gatherum Core Content Addressable Memory), a computer program for a content addressable memory in the central nervous system. This monograph will be useful to biologists, behavioral psychologists, neuropsychologists, neurophysiologists, biophysicists, and biochemists as well as computer scientists and mathematicians.
    • Pertussis Toxin

      • 1st Edition
      • December 2, 2012
      • Ronald Sekura
      • English
      • Paperback
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      Pertussis Toxin presents the proceeding of the Pertussis Toxin Conference, held in Bethesda, Maryland, on September 20–21, 1984. This book discusses the perspective of the pertussis toxin and the potential role of the toxin in the development of new acellular pertussis vaccines. Organized into 13 chapters, this text begins with an overview of the biological activities of pertussis vaccine, which enhanced the production of antibodies to antigens. This book then examines the interesting action of pertussis vaccine to stimulate antibody production, particularly as an effective adjuvant for the production of IgE isotype of antibodies. Other chapters consider the experimental approaches used in the study of the mechanisms by which hormones produce their physiological effect. The final chapter examines the several features of the Bordetella adenylate cyclase toxin, which suggest that the molecule may follow the A/B model proposed for a number of bacterial toxins. This book is a valuable resource for toxicologists, immunologists, bacteriologists, and pharmacologists.
    • Development, Anatomy, and Physiology

      • 1st Edition
      • December 2, 2012
      • A.D. Johnson
      • English
      • Paperback
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      • Hardback
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      The Testis, Volume I: Development, Anatomy, and Physiology focuses on the study of the testis. Particular concerns include embryology, morphology, physiology, cytology, and anatomy of this complex organ. Composed of contributions of authors that are divided into nine chapters, the book outlines the development of mammalian testis. Areas discussed include differentiation of the testis; genital glands and ducts; and postnatal development. The text highlights the relationship of this organ, along with the scrotum and epididymis, to the nervous system. The book discusses as well the supply of blood; secretion of fluid; and regulation of temperature of the testis. Concerns include testicular lymph and lymphatics; testicular fluid; and rete testis. The discussions proceed with an examination of the intertubular tissue of the testis. The selection ends with the discussions on the structure and functions of the testis. Noted are the presence of different cells and tissues that compose this organ and how these influence its functions. The selection is a good source of information for readers interested in studying the complex structure and functions of the testis.