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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Knobil and Neill's Physiology of Reproduction

      • 4th Edition
      • November 15, 2014
      • Tony M. Plant + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 1 7 5 3
      • eBook
        9 7 8 0 1 2 3 9 7 7 6 9 4
      The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context.

    • Conformation in Biology and Drug Design

      • 1st Edition
      • May 10, 2014
      • Sidney Udenfriend + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 4 5 7 4
      • eBook
        9 7 8 1 4 8 3 2 1 8 0 0 7
      The Peptides: Analysis, Synthesis, Biology, Volume 7: Conformation in Biology and Drug Design focuses on the analysis of peptides, emphasizing the use of physical methods in peptide conformational analysis and the relationship of conformational properties of peptides to biological properties. This book consists of nine chapters. Chapter 1 provides a brief overview of the perspective on the application of physical methods to peptide conformational analysis. The use of circular dichroism (CD) spectroscopy to examine the conformational properties of peptides in solution is elaborated in Chapter 2, while the use of fluorescence spectroscopy to examine the special relationships of aromatic side-chain groups to one another is discussed in Chapter 3. In Chapter 4, the use of various theoretical methods to calculate the conformations of peptides is described. The methods used to stimulate peptide conformations and dynamics are outlined in Chapter 5. The last four chapters examine various aspects of the use of nuclear magnetic resonance (NMR) in peptide conformational analysis. This volume is suitable for biologists, specialists, and researchers interested in peptides and proteins.

    • Electroporation-Based Therapies for Cancer

      • 1st Edition
      • July 25, 2014
      • Raji Sundararajan
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 5 2 7 8
      • Hardback
        9 7 8 1 9 0 7 5 6 8 1 5 2
      • eBook
        9 7 8 1 9 0 8 8 1 8 2 9 4
      Electroporation-Base... Therapies for Cancer reviews electroporation-base... clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-med... enhanced drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these patients for palliative and other care with enhanced quality of life. This book features discussions by interdisciplinary authors—including practicing oncological surgeons, medical professionals, and academic and other researchers—of the basics and clinical medical applications of electroporation.

    • Stem Cell Biology and Tissue Engineering in Dental Sciences

      • 1st Edition
      • November 5, 2014
      • Ajaykumar Vishwakarma + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 1 2 0 9
      • Hardback
        9 7 8 0 1 2 3 9 7 1 5 7 9
      • eBook
        9 7 8 0 1 2 3 9 7 7 7 8 6
      Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration.

    • Mammalian Protein Metabolism

      • 1st Edition
      • May 12, 2014
      • H. N. Munro + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 7 2 9 1 7
      Mammalian Protein Metabolism, Volume II focuses on the processes, methodologies, and reactions involved in mammalian protein metabolism, including toxicities, amino acid imbalance, and digestion and absorption. The selection first offers information on the nutritive value of dietary proteins, amino acid toxicities and imbalances, and protein requirements. Discussions focus on the protein requirements of adults, infants, and children, amino acid requirements, protein requirements in pregnancy, amino acid imbalance, mixed diets, and nutritive value and maintenance. The text then ponders on protein metabolism and requirements in pregnancy and lactation and protein metabolism and requirements in the newborn. The publication examines protein metabolism and requirements in the elderly; anomalies of amino acid metabolism; and physical injury and its effects on protein metabolism. Topics include general disturbance of protein metabolism following physical injury, nature of inflammatory reaction, acquired disturbances of amino acid metabolism, plasma proteins, nitrogen balance, digestion and absorption, and protein withdrawal. The text then elaborates on protein metabolism and tumor growth, experimental protein-calorie deficiency, and the clinical aspects of protein malnutrition. The selection is a dependable source of data for researchers interested in mammalian protein metabolism.

    • Mechanisms of Toxicity and Metabolism

      • 1st Edition
      • May 18, 2014
      • N. T. Kärki
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 3 2 7 2
      • eBook
        9 7 8 1 4 8 3 1 4 5 6 9 3
      Mechanisms of Toxicity and Metabolism is the sixth volume of the proceedings of the Sixth International Congress of Pharmacology, organized by the Finnish Pharmacological Society and held in Helsinki, Finland, on July 20-25, 1975. Contributors focus on the findings concerning the mechanisms of toxicity and metabolism and the developments in pharmacology and related areas of research. This volume has 24 chapters divided into four sections. After discussing the developmental aspects of drug metabolism and enzyme inhibitors of microbial origin, this book turns its attention to the interrelationships among various enzyme systems and physiological processes that are known to affect the distribution and metabolism of drugs. This text also highlights the reaction mechanisms of cytochrome P-450; the link between microsomal drug oxidation and glucuronidation; and the pharmacokinetics of the first pass effect. The reader is then introduced to the toxicity of food additives and the toxicity and metabolism of plasticizers and plastics. This volume concludes with a chapter that evaluates some of the biochemical and pharmacologic effects of di-2-ethylhexyl phthalate (DEHP). This book will appeal to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.

    • An Introduction to Biochemistry

      • 2nd Edition
      • May 12, 2014
      • William Robert Fearon
      • English
      • eBook
        9 7 8 1 4 8 3 2 2 5 3 9 5
      An Introduction to Biochemistry, Second Edition provides information pertinent to the fundamental aspects of biochemistry. This book presents several analytical methods, including the citrulline reaction for proteins and the diffusion test for acetone. Organized into two parts encompassing 25 chapters, this edition begins with an overview of the general composition of the organism and the chemical characteristics of the chief organic and inorganic compounds that enter into its structure. This text then examines the chemical composition of the tissues and physiological systems. Other chapters consider the occurrence and identification of several pathological constituents of urine, which presents features of biochemical interest. This book discusses as well the significance and analytical reactions of the bile acids and esters. The final chapter deals with the internal environment, which in the higher animal is represented by the blood and the cerebrospinal and other tissue fluids. This book is a valuable resource for biochemists.

    • Molecular Genetics of Sex Determination

      • 1st Edition
      • July 23, 2014
      • Stephen S. Wachtel
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 4 6 0 8
      • eBook
        9 7 8 1 4 8 3 2 9 5 5 8 9
      In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation. With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students.

    • Bone Cancer

      • 2nd Edition
      • August 27, 2014
      • Dominique Heymann
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 1 6 4 3
      • Hardback
        9 7 8 0 1 2 4 1 6 7 2 1 6
      • eBook
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      Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases – from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.

    • Year Book of Endocrinology 2014

      • 1st Edition
      • August 8, 2014
      • Matthias Schott
      • English
      • Hardback
        9 7 8 0 3 2 3 2 6 4 9 5 2
      • eBook
        9 7 8 0 3 2 3 2 6 4 9 6 9
      The Year Book of Endocrinology brings you abstracts of the articles that reported the year's breakthrough developments in endocrinology carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Diabetes, Lipoproteins and Ahterosclerosis, Obesity, Thyroid, Calcium and Bone Metabolism, Adrenal Cortex, and Neuroendocrinology are represented highlighting the most current and relevant articles in the field.

Related subjects

Biochemistry biophysics

Biotechnology

Endocrinology

Life sciences general

Molecular biology cellular biology and genetics

Physiology