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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Hyaluronan Signaling and Turnover

      • 1st Edition
      • Volume 123
      • July 23, 2014
      • Melanie Simpson + 1 more
      • English
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover.
    • Immunopathology of Insulin

      • 1st Edition
      • May 20, 2014
      • K. Federlin
      • F. Gross + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 9 7 6 1
      • eBook
        9 7 8 1 4 8 3 1 6 2 1 8 8
      Monographs on Endocrinology, Volume 6: Immunopathology of Insulin provides information pertinent to the fundamental aspects of immunopathology of insulin. This book covers a variety of topics, including cell mediated immunity, biological effects of insulin, insulin allergy, insulin immunology, and humoral insulin antibodies. Organized into six chapters, this volume begins with an overview of the causal relationship between delayed hypersensitivity and antibody production. This text then explains the molecular localization of the most important immunologic components of the insulin molecule. Other chapters consider the clinical observation of allergic reactions of insulin antibodies in the tissue and the in vitro method of standard serology. This book discusses as well methods used for demonstration of insulin antibodies in humans and experimental animals. The final chapter deals with the investigations concerned with the various kinds of immune reactions, which follow the injection of insulin. This book is a valuable resource for endocrinologists, immunologists, and diabetologists.
    • The Role of Chromosomes in Development

      • 1st Edition
      • June 5, 2014
      • Michael Locke
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 4 2 1 0
      • eBook
        9 7 8 1 4 8 3 2 6 3 6 5 6
      The Role of Chromosomes in Development is a collection of papers that deals with structural patterns and functional organization of chromosomes. Some papers discuss chromosomal proteins, DNA replication sequences in higher animals, and the implications of localized DNA synthesis in polytene chromosomes. Several papers describe chromosomal RNA, nuclear RNA fractions, genetic control, and the regulation of developmental pathways. One paper concerns the "bithorax" series that controls the development of certain body segments of the fly in a polarized and coordinated manner reminiscent of the genes in the operons of microorganisms. The bithorax genes evidently exploit and amplify a gradient arising from an anteroposterior gradient during mitotic division rates. The bithorax genes produces a whole set of new substances that repress certain systems of cellular differentiation, letting other systems to emerge and develop. Another paper investigates the hypothesis of diploid subnuclei as the architectural subunit of the ciliate macronucleus, as well as the hypothesis of "allelic repression" as the basis for certain examples of subnuclear differentiation. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology.
    • Laboratory Methods in Enzymology: Protein Part B

      • 1st Edition
      • Volume 539
      • February 24, 2014
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 1 2 0 0
      • eBook
        9 7 8 0 1 2 4 2 0 1 7 9 8
      Laboratory Methods in Enzymology: Protein Part B brings together a number of core protocols concentrating on protein, carefully written and edited by experts.
    • Advances in Cancer Research

      • 1st Edition
      • Volume 121
      • May 29, 2014
      • Kenneth D. Tew + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 2 4 9 0
      • eBook
        9 7 8 0 1 2 8 0 0 3 1 7 6
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.
    • Nuclear Pore Complexes and Nucleocytoplasmic Transport - Methods

      • 1st Edition
      • Volume 122
      • May 20, 2014
      • English
      • Hardback
        9 7 8 0 1 2 4 1 7 1 6 0 2
      • eBook
        9 7 8 0 1 2 4 1 7 1 7 8 7
      Volume 122 of Methods in Cell Biology describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (including mammalian cells, Xenopus, C. elegans, yeast). The volume enables investigators to analyze nuclear pore complex structure, assembly, and dynamics; to evaluate protein and RNA trafficking through the nuclear envelope; and to design in vivo or in vitro assays appropriate to their research needs. Beyond the study of nuclear pores and transport as such, these protocols will also be helpful to scientists characterizing gene regulation, signal transduction, cell cycle, viral infections, or aging. The NPC being one of the largest multiprotein complexes in the cell, some protocols will also be of interest for people currently characterizing other macromolecular assemblies. This book is thus designed for laboratory use by graduate students, technicians, and researchers in many molecular and cellular disciplines.
    • Micropatterning in Cell Biology, Part A

      • 1st Edition
      • Volume 119
      • January 16, 2014
      • English
      • Hardback
        9 7 8 0 1 2 4 1 6 7 4 2 1
      • eBook
        9 7 8 0 1 2 4 1 6 7 4 6 9
      This new volume of Methods in Cell Biology looks at micropatterning in cell biology and includes chapters on protein photo-patterning on PEG with benzophenone, laser-directed cell printing and dip pen nanolithography. The cutting-edge material in this comprehensive collection is intended to guide researchers for years to come.
    • Advances in Genetics

      • 1st Edition
      • Volume 87
      • October 9, 2014
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 1 4 9 3
      • eBook
        9 7 8 0 1 2 8 0 0 3 6 9 5
      The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Volume 87 presents an eclectic mix of articles of use to all human and molecular geneticists on topics including: gene transfer, fruiting body development and the genetics of Alzheimer’s disease; and more.
    • Pathobiology of Human Disease

      • 1st Edition
      • August 1, 2014
      • Linda M. McManus + 1 more
      • English
      • eBook
        9 7 8 0 1 2 3 8 6 4 5 7 4
      Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students.
    • The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

      • 1st Edition
      • Volume 546
      • November 4, 2014
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 1 8 5 0
      • eBook
        9 7 8 0 1 2 8 0 1 3 3 4 2
      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells.