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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • A Quick Reference to Obstetric Anesthesia

    • 1st Edition
    • Adithya Devadas Bhat + 1 more
    • English
    A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patients. It covers the newest evidence on various critical topics in obstetric anesthesia, and the inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an “in the moment” tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, as well as numerous emerging topics that are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible information to facilitate real-time care of pregnant patients. Its approachable yet comprehensive knowledge base will be appreciated by anesthesia professionals at every level.

  • ATP

    From Neurotransmission to Cancer Therapy
    • 1st Edition
    • Ronald Sluyter + 5 more
    • English
    ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the “Molecular Mediators in Health and Disease” series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond.

  • Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis

    • 1st Edition
    • Jyotsna Kailashiya
    • English
    Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis is a groundbreaking resource that delves into the impact of filarial parasites on platelet functions in humans. This comprehensive work explores the intricate signaling and immunological pathways affected by these interactions, filling a significant gap in the existing literature. The book is particularly valuable for researchers, scientists, and clinicians involved in the management and study of lymphatic filariasis, commonly known as elephantiasis; and also human platelets. With limited prior information on the interplay between human platelets and filarial parasites, this text offers a fresh perspective that could enhance patient management strategies. By understanding these interactions, healthcare professionals may unlock new avenues for effective treatment and prevention of lymphatic filariasis. This book is essential for anyone looking to deepen their understanding of the disease and contribute to its potential elimination.

  • Diabetes, Aging, and Management Strategies

    Cellular Mechanisms for Healthy Aging
    • 1st Edition
    • Younis Ahmad Hajam + 2 more
    • English
    Diabetes, Aging, and Management Strategies: Cellular Mechanisms for Healthy Aging is a comprehensive guide that explores the complex interplay between diabetes and the aging process. The book dives deeply into the scientific mechanisms underlying diabetes and aging, offering insights into how aging accelerates disease processes and affects metabolic pathways, organ function, and overall health. With a focus on the biological, clinical, and practical aspects of diabetes in the elderly, this book provides actionable information on the pathophysiology of diabetes in aging individuals, evidence-based mitigation strategies, and effective management approaches.As populations worldwide grow older, the prevalence of diabetes continues to rise, presenting new challenges in understanding, managing, and mitigating the effects of this condition on older adults. This book is designed to support healthcare professionals, researchers, and policymakers in creating and implementing strategies that address the unique needs of this population.

  • Mathematical Concepts and Methods in Modern Biology

    Using Modern Discrete Models
    • 2nd Edition
    • Raina Robeva
    • English
    Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models, Second Edition presents an updated, quantitative framework for analyzing, predicting, and modulating complex biological systems. Structured around project-based learning and problem-solving, it integrates essential mathematical concepts and methods in the context of key biological questions. Topics include gene regulatory and neuronal networks, CpG islands, plant population growth, interacting populations, phylogenetics, and phylogenomics. Modeling tools span discrete dynamical systems (including deterministic and stochastic Boolean networks), ordinary differential equations, projection matrices, agent-based modeling, polynomial ideals, Gröbner bases, tropical algebra, and other algebraic approaches. Computation is supported by a range of software tools, including some developed for this book, as well as open source, freely available, and proprietary platforms. Updated code examples and step-by-step instructions illustrate software use, making this a valuable resource for health professionals, scientists, researchers, and students in related fields.

  • The Resistance of Cervical Cancer to Chemotherapy and its Reversal

    • 1st Edition
    • Volume 9
    • S. Muthusami
    • English
    The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers.In 10 chapters, this book first provides an introduction and history of cervical cancer; next, it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists, and clinicians interested in building a comprehensive understanding of the field.

  • Episodes in the History of Medical Science

    Discovery Meets Orthodoxy
    • 1st Edition
    • Anthony R. Rees
    • English
    Episodes in the History of Medical Science: Discovery Confronts Orthodoxy highlights key moments in history where scientific and medical advances faced acceptance and rejection by the prevailing orthodoxy. This book places present-day disease protection in context by exploring significant medical and scientific theories, their success stories, challenges, and the frequent resistance to new ideas. It shows how acceptance of scientific discoveries often lags due to conservatism within the scientific community and broader socio-political and cultural influences. The book examines the origins of medical theory and practice, from the revolutionary ideas of Hippocrates and Galen to the rise of Islamic Medicine and the scholasticism of the Middle Ages. It covers the arrival of syphilis in Europe and the ensuing medical debates, the historical battle against smallpox through variolation and vaccination, and the skepticism faced by groundbreaking discoveries in the 19th and 20th centuries. Key topics include the gene debate, the thalidomide tragedy, the antibody revolution, and the paradigm shift in understanding stomach ulcers. The narrative also addresses the modern era's anti-vaccinationism and vaccine hesitancy, emphasizing the ongoing tension between scientific integrity and public acceptance. Episodes in the History of Medical Science: Discovery Confronts Orthodoxy is a valuable resource for medical professionals, researchers, historians, and students. It underscores the importance of scientific and medical integrity, the pursuit of truth, and validated scientific communication. By providing historical insights and examples of perseverance in the face of skepticism, this book offers valuable lessons for improving public health and understanding the dynamic journey of medical science.

  • Biostatistical Methods and Applications

    Experiment Design, Analysis, and Presenting Findings
    • 1st Edition
    • Jitendra Kumar Chaudhary
    • English
    Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings provides students and researchers with the skills needed to apply biostatistical concepts and implement a wide range of analytical tools. The text is an accessible and intentionally curated resource that instructs readers in designing experiments, considering the results, and presenting statistical findings and views. In twenty-four chapters and additional appendices, the book starts with an introduction to the field of statistics and from there covers experiment design, data coding, and data collection methods. The book also delves into descriptive statistics, probability, statistical distributions, correlations, and regression. Common research techniques such as normality tests, sample size determination, missing data analysis, statistical inference, test of significance, and ANOVA are explained in a clear manner so that readers can successfully understand and apply these methods. Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings thoroughly explores fundamental topics in biostatistics to guide readers in conducting statistical analysis and interpretation by using the step-by-step procedures and diagrams in the book. This book covers current topics which are being used frequently in teaching and research areas, as well as specific statistical techniques including multivariate analysis, binary logistic regression, and non-parametric methods. This valuable first edition provides the necessary tools and conceptual foundations in quantitative reasoning to efficiently extract information from a vast sea of data, and to communicate research findings in order to support hypotheses and give credibility to research methodology and conclusions. With detailed explanations, illustrative examples and diagrams, and beneficial in-text exercises and solutions to support the study of biostatistics, this textbook will prove useful to students, researchers, and scientists who aim to increase their precision around methods and techniques in this field.

  • Encyclopedia of Endocrine Diseases

    • 3rd Edition
    • Ilpo Huhtaniemi
    • English
    The Encyclopedia of Endocrine Diseases, Third Edition, Five Volume Set is an essential one-stop reference exploring physiological, clinical diagnostic and therapeutic aspects of a wide range of endocrine and endocrine-related metabolic diseases. This edition incorporates ground-breaking research that has occurred in the last 8 years particularly in molecular mechanisms such as mutations, epigenetics and signaling, environmental effects on homeostasis, and the pathogenesis of common endocrine diseases including endocrine malignancies, obesity, and diabetes.Among the most complex constructs in the body, the endocrine system sends chemical signals to specific receptors in other parts of the body, eliciting intracellular signaling pathways as their biological effect. The endocrine system regulates numerous processes including metabolism, biological cycles, internal fluid volume, reproduction and growth to maintain body homeostasis. However, the ways in which endocrine functioning can go awry are numerous. Providing over 420 updated articles, this 5 volume edition of Encyclopedia of Endocrine Diseases explores the extensive spectrum of metabolic and endocrine disease, capturing new diagnosis techniques, treatment methods and understanding of endocrine pathogenesis.This text, unique in its vast coverage and clear layout, is not only an indispensable resource for clinical professionals and researchers in endocrinology, but also accessible to advanced and undergraduate students.

  • Genetics of Bone Biology and Skeletal Disease

    • 3rd Edition
    • Rajesh V. Thakker + 3 more
    • English
    Genetics of Bone Biology and Skeletal Disease, Third Edition is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid, and related disorders, and vitamin D and renal disorders.Sections cover bone biology and structure, joint and cartilage biology, principles of endocrine regulation, the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasia, rarer bone disorders, and much more.

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