Fundamentals of Space Medicine and Clinical Technology
- 1st Edition - December 16, 2025
- Latest edition
- Editors: Ethan Waisberg, Joshua Ong, Andrew G. Lee
- Language: English
Fundamentals of Space Medicine and Clinical Technology is a comprehensive guide that delves into the advanced technologies utilized in space medicine today. The book is struct… Read more
Fundamentals of Space Medicine and Clinical Technology is a comprehensive guide that delves into the advanced technologies utilized in space medicine today. The book is structured into three sections: an introduction to the physiology of space medicine, a detailed overview of various space medicine technologies, and the application of these technologies on Earth. Authored by leading experts in the field, it aims to bridge the gap between space medicine physiology and technological advancements, offering valuable insights. Additionally, the book serves as a useful resource for doctors, engineers, commercial industries, and governments, highlighting the significance of translational applications of space medicine technologies.
This is a pivotal read for anyone interested in the intersection of space exploration and medical science.
This is a pivotal read for anyone interested in the intersection of space exploration and medical science.
- Introduces readers to space medicine physiology
- Presents a variety of space medicine technologies
- Includes translational applications of the technologies
Researchers and professionals in the space medicine industry, including doctors, engineers, commercial industries and governments
Section 1: Physiological changes in space
1. Cardiac changes in space
Keval Dipan Patel and Benjamin D. Levine
2. Skeletal muscle adaptations to spaceflight: mechanisms and countermeasures
Khaled Y. Kamal, Marina Trombetta-Lima, Kenneth Lam, Kacey Davis, Brianna Jorgensen, Cole Thomsen, Alhassan Abdalla, John M. Lawler and Joshua T. Selsby
3. Neurological adaptations to spaceflight
Anurag Sakharkar, JangKeun Kim, Bader H. Shirah and Christopher E. Mason
4. Immune dysfunction
Odette Laneuville
5. Spaceflight-associated neuro-ocular syndrome
Yannie Guo, Joshua Ong, Ethan Waisberg and Andrew G. Lee
6. Viral evolution in the cosmos
Nidia S. Trovao, Alexander G. Lucaci, Nikhil Pradeep, Meher Sethi, Lisa M. Bono, Ruth Subhash Singh, Kevin B. Clark, Victoria Zaksas, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Kevin Zambrano, Rashid Karim, Corey A. Theriot, Guliz Otkiran, Dirk Neefs, Gaetano Isola, Gianluca Tartaglia, Michael Schotsaert, Sana Tamim, Saswati Das, Michael Fasullo, Nilufar Ali, Denis Fargette, Nicholas J.B. Brereton, Afshin Beheshti, Joseph W. Guarnieri and Eve Syrkin Wurtele
7. Astronaut multi-omics
JangKeun Kim, Anurag Sakharkar, Jeremy Wain Hirschberg, Nathan Schanzer, Zachary Feinstein, Erik W. LeRoy, Marissa Burke, Kübra Can Kurt, Krista Ryon, Shray Parimoo, Aaron Berliner, Theodore M. Nelson and Christopher E. Mason
8. Metabolic and endocrine changes in spaceflight
Kevin Sean O’Leary, Zeynep Melis Güner, Begüm Mathyk and Feyza Erenler
9. Reproduction and obstetrics in space
Jessica D’Urbano and Sumbal Mushtaq
10. Immunometabolism in space
Nima Gharahdaghi and Arian Laurence
11. Effects of altered gravity on the liver
Ben Cools and Mathieu Vinken
12. Dermatologic conditions in space
Matilde Miranda, Malay Shah and Christopher Hai Nam Nguyen
13. Circadian rhythm changes in space
Kuniaki Otsuka, Germaine Cornelissen, Larry A. Beaty and Chiaki Mukai
14. Ocular surface, anterior segment, and lens in spaceflight
Ryung Lee, Joshua Ong, Ethan Waisberg, John Berdahl and Andrew G. Lee
15. MicroRNAs in space: biomarkers for health risk assessment and targets for countermeasures
David Geng, Bidisha Pal, Nikhil Pradeep, John Hajj, Tânia Amorim, Victoria Zaksas, Param Sharma, Srinivasulu Yerukala Sathipati, Amrita Sahu, Kanhaiya Singh, Ana Lúcia Leitão, Joel S. Greenberger, Francisco J. Enguita and Afshin Beheshti
16. Gut microbiota and intervention of probiotics in spaceflight
Nikhil Pradeep, Stefan J. Green and Adit Chaudhary
Section 2: Space medicine technology and countermeasures
18. Spacesuits and extravehicular activity
Logan Kluis, Brad Holschuh and Ana Diaz-Artiles
19. Ultrasound in space
Paul Bradley McBeth and Randy W.J. Moore
20. Hybrid training system in space flight
Naoto Shiba, Hiroo Matsuse and Hiroshi Tajima
21. Regenerative medicine in space
Cynthia Viera-Catota, Sebastián Chile-Miranda, Diego Villavicencio, Alissen Haro-Vinueza, Abigail Benavides-Almeida, Quentin Perrier, Brian Billings, Sampada Koirala, Camila Pazmiño, Michella Dirani, Camila Lopez, Flavio Salazar, Auki Guaillas, Kunal Mitra and Andrés Caicedo
22. Digital clinicians in spaceflight and off-Earth habitation
Kevin B. Clark
23. Bone health countermeasures
Tânia Amorim, Jenna Goulart, Kristen Koltun, Afshin Beheshti, Jeffrey Willey and Mary L. Bouxsein
24. Precision medicine in human spaceflight: applying systems thinking to principles, concepts, and methods of assessment
Michael A. Schmidt, Julian C. Schmidt and Caleb M. Schmidt
25. Virtual and augmented reality in space
Jawshan Ara and Prithul Sarker
26. Artificial intelligence in space
Jay M. Jaber, Ciana Sorrels and Shubh Desai
27. Advanced technologies in deep space exploration and clinical applications
Rahul Kumar, Ethan Waisberg and Joshua Ong
28. Organoid research in space for human health
Katarzyna M. Piekarz
29. Open science in space medicine: perspectives following the White House Office of Science and Technology Policy Open Science Sessions for early career researchers
Ethan Waisberg, Joshua Ong and Andrew G. Lee
30. Eye tracking during spaceflight: current technology and future directions for spaceflight-associated neuro-ocular syndrome
Maria Rivolta, Joshua Ong, Ethan Waisberg, Nasif Zaman, Lynn Stanwyck, Prithul Sarker, Alireza Tavakkoli and Andrew G. Lee
31. Short-arm centrifuge artificial gravity for space station
Kazuhito Shimada
32. LASER body mass measurement device
Kazuhito Shimada
33. Space station atmosphere lint mitigation
Kazuhito Shimada
34. Health impacts of radiation in space and countermeasures
Alexia Tasoula, Floriane Poignant, Joseph W. Guarnieri, Hansjorg Schwertz and Gregory A. Nelson
35. Advancing surgical autonomy in space: microgravity-optimized procedures, technologies, and countermeasures for the International Space Station
Rahul Kumar, Ethan Waisberg and Joshua Ong
1. Cardiac changes in space
Keval Dipan Patel and Benjamin D. Levine
2. Skeletal muscle adaptations to spaceflight: mechanisms and countermeasures
Khaled Y. Kamal, Marina Trombetta-Lima, Kenneth Lam, Kacey Davis, Brianna Jorgensen, Cole Thomsen, Alhassan Abdalla, John M. Lawler and Joshua T. Selsby
3. Neurological adaptations to spaceflight
Anurag Sakharkar, JangKeun Kim, Bader H. Shirah and Christopher E. Mason
4. Immune dysfunction
Odette Laneuville
5. Spaceflight-associated neuro-ocular syndrome
Yannie Guo, Joshua Ong, Ethan Waisberg and Andrew G. Lee
6. Viral evolution in the cosmos
Nidia S. Trovao, Alexander G. Lucaci, Nikhil Pradeep, Meher Sethi, Lisa M. Bono, Ruth Subhash Singh, Kevin B. Clark, Victoria Zaksas, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Kevin Zambrano, Rashid Karim, Corey A. Theriot, Guliz Otkiran, Dirk Neefs, Gaetano Isola, Gianluca Tartaglia, Michael Schotsaert, Sana Tamim, Saswati Das, Michael Fasullo, Nilufar Ali, Denis Fargette, Nicholas J.B. Brereton, Afshin Beheshti, Joseph W. Guarnieri and Eve Syrkin Wurtele
7. Astronaut multi-omics
JangKeun Kim, Anurag Sakharkar, Jeremy Wain Hirschberg, Nathan Schanzer, Zachary Feinstein, Erik W. LeRoy, Marissa Burke, Kübra Can Kurt, Krista Ryon, Shray Parimoo, Aaron Berliner, Theodore M. Nelson and Christopher E. Mason
8. Metabolic and endocrine changes in spaceflight
Kevin Sean O’Leary, Zeynep Melis Güner, Begüm Mathyk and Feyza Erenler
9. Reproduction and obstetrics in space
Jessica D’Urbano and Sumbal Mushtaq
10. Immunometabolism in space
Nima Gharahdaghi and Arian Laurence
11. Effects of altered gravity on the liver
Ben Cools and Mathieu Vinken
12. Dermatologic conditions in space
Matilde Miranda, Malay Shah and Christopher Hai Nam Nguyen
13. Circadian rhythm changes in space
Kuniaki Otsuka, Germaine Cornelissen, Larry A. Beaty and Chiaki Mukai
14. Ocular surface, anterior segment, and lens in spaceflight
Ryung Lee, Joshua Ong, Ethan Waisberg, John Berdahl and Andrew G. Lee
15. MicroRNAs in space: biomarkers for health risk assessment and targets for countermeasures
David Geng, Bidisha Pal, Nikhil Pradeep, John Hajj, Tânia Amorim, Victoria Zaksas, Param Sharma, Srinivasulu Yerukala Sathipati, Amrita Sahu, Kanhaiya Singh, Ana Lúcia Leitão, Joel S. Greenberger, Francisco J. Enguita and Afshin Beheshti
16. Gut microbiota and intervention of probiotics in spaceflight
Nikhil Pradeep, Stefan J. Green and Adit Chaudhary
Section 2: Space medicine technology and countermeasures
18. Spacesuits and extravehicular activity
Logan Kluis, Brad Holschuh and Ana Diaz-Artiles
19. Ultrasound in space
Paul Bradley McBeth and Randy W.J. Moore
20. Hybrid training system in space flight
Naoto Shiba, Hiroo Matsuse and Hiroshi Tajima
21. Regenerative medicine in space
Cynthia Viera-Catota, Sebastián Chile-Miranda, Diego Villavicencio, Alissen Haro-Vinueza, Abigail Benavides-Almeida, Quentin Perrier, Brian Billings, Sampada Koirala, Camila Pazmiño, Michella Dirani, Camila Lopez, Flavio Salazar, Auki Guaillas, Kunal Mitra and Andrés Caicedo
22. Digital clinicians in spaceflight and off-Earth habitation
Kevin B. Clark
23. Bone health countermeasures
Tânia Amorim, Jenna Goulart, Kristen Koltun, Afshin Beheshti, Jeffrey Willey and Mary L. Bouxsein
24. Precision medicine in human spaceflight: applying systems thinking to principles, concepts, and methods of assessment
Michael A. Schmidt, Julian C. Schmidt and Caleb M. Schmidt
25. Virtual and augmented reality in space
Jawshan Ara and Prithul Sarker
26. Artificial intelligence in space
Jay M. Jaber, Ciana Sorrels and Shubh Desai
27. Advanced technologies in deep space exploration and clinical applications
Rahul Kumar, Ethan Waisberg and Joshua Ong
28. Organoid research in space for human health
Katarzyna M. Piekarz
29. Open science in space medicine: perspectives following the White House Office of Science and Technology Policy Open Science Sessions for early career researchers
Ethan Waisberg, Joshua Ong and Andrew G. Lee
30. Eye tracking during spaceflight: current technology and future directions for spaceflight-associated neuro-ocular syndrome
Maria Rivolta, Joshua Ong, Ethan Waisberg, Nasif Zaman, Lynn Stanwyck, Prithul Sarker, Alireza Tavakkoli and Andrew G. Lee
31. Short-arm centrifuge artificial gravity for space station
Kazuhito Shimada
32. LASER body mass measurement device
Kazuhito Shimada
33. Space station atmosphere lint mitigation
Kazuhito Shimada
34. Health impacts of radiation in space and countermeasures
Alexia Tasoula, Floriane Poignant, Joseph W. Guarnieri, Hansjorg Schwertz and Gregory A. Nelson
35. Advancing surgical autonomy in space: microgravity-optimized procedures, technologies, and countermeasures for the International Space Station
Rahul Kumar, Ethan Waisberg and Joshua Ong
- Edition: 1
- Latest edition
- Published: December 16, 2025
- Language: English
EW
Ethan Waisberg
Dr. Ethan Waisberg is an Academic Foundation Doctor at the University of Cambridge, in the UK. He conducts research in Spaceflight Associate Neuro-Ocular Syndrome, is a member of of NASA's Artificial Intelligence and Machine Learning Working Group and has co-published leading papers in space medicine, neuro-ophthalmology, extended reality, and artificial intelligence.
Affiliations and expertise
Department of Clinical Neurosciences, University of Cambridge, Cambridge, United KingdomJO
Joshua Ong
Joshua Ong, MD is a resident physician with a passion for protecting astronaut health. He has conducted research on several space medicine research projects, including a project that launched into space. He has presented at the National Aeronautics and Space Administration (NASA) Human Research Program Investigators' Workshop and strives to continue his lifelong journey in ophthalmology and space medicine.
Affiliations and expertise
Department of Ophthalmology and Visual Sciences, University of Michigan Kellogg Eye Center, Ann Arbor, MI, United StatesAL
Andrew G. Lee
Dr. Lee began his academic career in 1994 as an Instructor in the Department of Ophthalmology, Neurology, and Neurosurgery at Baylor College of Medicine, becoming an Associate Professor in 1998. In 2000, he joined the University of Iowa as an Associate Professor and later became a full Professor. He serves on the editorial boards of 12 journals, including the American Journal of Ophthalmology, and is the Editor in Chief of the Journal of Academic Ophthalmology. A recipient of multiple awards from the American Academy of Ophthalmology, Dr. Lee has a strong interest in resident training and has published extensively on teaching methods in ophthalmology residency programs. In 2009, he joined Houston Methodist Hospital and Research Institute, where he currently serves as Chair of the Blanton Eye Institute and is a Professor at Weill Cornell Medical College.
Affiliations and expertise
Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, United States; Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medical College, New York, NY, United StatesRead Fundamentals of Space Medicine and Clinical Technology on ScienceDirect