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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Cellular and Animal Models in Human Genomics Research

      • 1st Edition
      • July 30, 2019
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 5 7 3 7
      • eBook
        9 7 8 0 1 2 8 1 6 5 7 4 4
      Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth.

    • Self-assessment Questions for Clinical Molecular Genetics

      • 1st Edition
      • May 28, 2019
      • Haiying Meng
      • English
      • Paperback
        9 7 8 0 1 2 8 0 9 9 6 7 4
      • eBook
        9 7 8 0 1 2 8 0 9 9 6 8 1
      Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge.

    • GPCRs

      • 1st Edition
      • September 11, 2019
      • Beata Jastrzebska + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 2 2 8 6
      • eBook
        9 7 8 0 1 2 8 1 6 7 2 8 1
      GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth.

    • Clinical Genome Sequencing

      • 1st Edition
      • March 30, 2019
      • Aad Tibben + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 3 3 3 5 4
      • eBook
        9 7 8 0 1 2 8 1 3 3 3 6 1
      Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.

    • Global Perspectives on Childhood Obesity

      • 2nd Edition
      • February 6, 2019
      • Debasis Bagchi
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 8 4 0 4
      • eBook
        9 7 8 0 1 2 8 1 2 8 4 1 1
      Global Perspectives on Childhood Obesity: Current Status, Consequences and Prevention, Second Edition examines the current childhood obesity epidemic, outlines the consequences of this crisis, and develops strategies to forestall and prevent it. This book provides a thorough investigation of the causes of childhood obesity and, more importantly, offers specific prevention strategies that can be used by medical and mental health professionals, policymakers, community organizers, and individuals. New chapters on BMI and cardiovascular disease, exercise, neurotransmitters, neurocognition, nutrigenomics and combined prevention strategies are included, making this a solid introduction on the childhood obesity crisis. Researchers, practitioners, and advanced students in public health, health policy, and health economics, as well those working in medicine, pharmacy, nutrition, school health, physiology, and neuroscience related to obesity will find this to be a comprehensive resource.

    • Computational Modeling in Bioengineering and Bioinformatics

      • 1st Edition
      • October 1, 2019
      • Nenad Filipovic
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 5 8 3 3
      • eBook
        9 7 8 0 1 2 8 1 9 5 8 4 0
      Computational Modeling in Bioengineering and Bioinformatics promotes complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, and in the environment, public health, drug design, and so on. It provides a common platform by bridging these two very important and complementary disciplines into an interactive and attractive forum. Chapters cover biomechanics and bioimaging, biomedical decision support system, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, biomedical image processing, analysis and visualization, high performance computing and sports bioengineering. The book's chapters are the result of many international projects in the area of bioengineering and bioinformatics done at the Research and Development Center for Bioengineering BioIRC and by the Faculty of Engineering at the University of Kragujevac, Serbia.

    • Reproducibility in Biomedical Research

      • 1st Edition
      • March 14, 2019
      • Erwin B. Montgomery Jr.
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 4 4 3 2
      • eBook
        9 7 8 0 1 2 8 1 7 6 7 2 6
      Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproducibility, including logic, distinguishing productive from unproductive irreproducibility, the scientific method, and the use of statistics. In multiple examples and six detailed case studies, the book demonstrates the misuse of logic resulting in unproductive irreproducibility, allowing researchers to develop their own logic and planning abilities. Biomedical researchers, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine will find the arguments and explorations a valuable addition to their libraries.

    • Nontuberculous Mycobacteria (NTM)

      • 1st Edition
      • January 10, 2019
      • Ali Akbar Velayati + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 6 9 2 7
      • eBook
        9 7 8 0 1 2 8 1 4 6 9 3 4
      Nontuberculous Mycobacteria (NTM): Microbiological, Clinical and Geographical Distribution is a complete reference that stimulates a greater understanding of NTM infections. Sections cover microbiologic and molecular diagnostic tools, drug susceptibility tests, human genetic susceptibility, prevalence and incidence studies, clinical and radiological presentations, and clinical trials for antibiotic therapy. With the incidence rate of NTM infections increasing globally during the last decade, significant mortality and morbidity must be addressed. This important reference will provide research scientists, clinical microbiologists, hospital diagnostic technicians, and post graduate medical and science students with information on the epidemiology, prevalence, microbiology and clinical aspects of NTM.

    • Nocturia

      • 1st Edition
      • August 28, 2019
      • King C. Lee + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 0 9 7 1
      • eBook
        9 7 8 0 1 2 8 2 0 3 0 6 4
      Nocturia: Etiology, Pathology, Risk Factors, Treatment and Emerging Therapy includes the background, prevalence, etiology, risk factors, adverse effects and morbidity, as well as current and emerging treatments related to nocturia. Often considered a normal part of aging, nocturia can often be overlooked as a risk factor associated with serious outcomes such as mortality, morbidity, negative economic implications and decreased quality of life. This book provides comprehensive information on all aspects of nocturia as well as how the emerging therapies can provide safe, effective and low-cost treatment. This is an important reference for researchers, urologists and clinicians interested in improving diagnosis and treatment of nocturia.

    • 250 examens de laboratoire

      • 13th Edition
      • May 3, 2019
      • René Caquet
      • French
      • eBook
        9 7 8 2 2 9 4 7 6 4 6 4 6
      Les examens de laboratoire, parfois qualifiés d’examens «complémentaires» alors qu’ils sont indispensables, recherchent bactéries et virus, reconnaissent les cellules anormales, détectent les anticorps, évaluent le fonctionnement des organes, scrutent le milieu intérieur, examinent les gènes.Comment s’en passer ?Ce livre, élaboré par un clinicien, offre aux professionnels de santé un instrument de pratique quotidienne. Ouvrage de référence, il expose tout ce qu’il faut savoir pour prescrire des analyses médicales et interpréter les résultats.Les examens de laboratoire sont présentés sous forme de fiches, classées par ordre alphabétique, qui suivent un plan récurrent : mode et précautions de prélèvement, valeurs normales et cliniques (valeurs pathologiques), objectifs de l’examen et interprétation.Cet ouvrage décrit le raisonnement qui permet de déduire d’un résultat biologique les meilleures conclusions diagnostiques ou thérapeutiques possibles, en interprétant les résultats à la lumière de la clinique, de la littérature scientifique et des données de santé publique.Cette 13e édition est entièrement actualisée, notamment en fonction des publications récentes, des recommandations des sociétés savantes (VIH, allergies, auto-immunité...) et en accord avec la nomenclature de la Sécurité sociale.De nouveaux examens liés à l’actualité médicale (caryotype onco-hématologique, hématocrite, hépatite E…) sont ajoutés.L’ouvrage s’accorde volontairement à la pratique des généralistes, spécialistes et biologistes. Les examens plus rares (biologie moléculaire…) sont traités en accord avec la demande.

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