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Elsevier

Reproducibility in Biomedical Research

Epistemological and Statistical Problems

Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproduci… Read more

Description

Reproducibility in Biomedical Research: Epistemological and Statistical Problems explores the ideas and conundrums inherent in scientific research. It explores factors of reproducibility, including logic, distinguishing productive from unproductive irreproducibility, the scientific method, and the use of statistics. In multiple examples and six detailed case studies, the book demonstrates the misuse of logic resulting in unproductive irreproducibility, allowing researchers to develop their own logic and planning abilities. Biomedical researchers, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine will find the arguments and explorations a valuable addition to their libraries.

Key features

  • Considers the meaning and purpose of reproducibility to help design research
  • Reviews famous case studies of alleged irreproducibility to determine if these could be reproducible
  • Provides a theoretical aspect to practical issues surrounding research design and conduct

Readership

Researchers and advanced students in biomedical fields, clinicians, administrators of scientific institutions and funding agencies, journal editors, philosophers of science and medicine

Table of contents

1. Introduction2. Validity of Biomedical Science, Reproducibility and Irreproducibility3. The Logic of Certainty versus the Logic of Discovery4. The Logic of Probability and Statistics5. Causation, Process Metaphor, and Reductionism6. Case Studies in Clinical Biomedical Research7. Case Studies in Basic Biomedical Research8. Case Studies in Computational Biomedical Research9. Chaotic and Complex Systems, Statistics, and Far-from-Equilibrium Thermodynamics10. Epilogue

Product details

About the author

EM

Erwin B. Montgomery Jr.

Dr. Montgomery has been an academic neurologist for over 40 years pursuing teaching, clinical and basic research at major academic medical centers. He has authored over 120 peer reviewed journal articles (available on PubMed) and 8 books on medicine (4 on the subject of Deep Brain Stimulation). The last two have been “Reproducibility in Biomedical Research” (Academic Press, 2024) and “The Ethics of Everyday Medicine” (Academic Press, 2023).
Affiliations and expertise
Emeritus Professor, Department of Medicine (Neurology), McMaster University, Hamilton, ON, Canada

View book on ScienceDirect

Read Reproducibility in Biomedical Research on ScienceDirect