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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Pan-genomics: Applications, Challenges, and Future Prospects

      • 1st Edition
      • March 6, 2020
      • Debmalya Barh + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 0 7 6 2
      • eBook
        9 7 8 0 1 2 8 1 7 0 7 7 9
      Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics,” thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.

    • Emerging Technologies for Heart Diseases

      • 1st Edition
      • August 19, 2020
      • Udi Nussinovitch
      • English
      • Hardback
        9 7 8 0 1 2 8 1 3 7 0 4 8
      • eBook
        9 7 8 0 1 2 8 1 3 7 0 5 5
      The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options.

    • Ethical Considerations When Preparing a Clinical Research Protocol

      • 2nd Edition
      • June 11, 2020
      • Evan DeRenzo + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 3 8 6 9 3 5 7
      • eBook
        9 7 8 0 1 2 3 8 6 9 5 4 8
      Ethical Considerations When Preparing a Clinical Research Protocol, Second Edition, provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, how to design appropriate research studies, how to consent and assent documents, how to get protocols approved, special populations, confidentiality issues, and the reporting of adverse events. The book's valuable appendix includes a listing of web resources about research ethics, along with a glossary, making it an invaluable resource for scientists collaborating in clinical trials, physician investigators, clinical research fellows, and more.

    • Vibrational Spectroscopy in Protein Research

      • 1st Edition
      • May 19, 2020
      • Yukihiro Ozaki + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 6 1 0 7
      • eBook
        9 7 8 0 1 2 8 1 8 6 1 1 4
      Vibrational Spectroscopy in Protein Research offers a thorough discussion of vibrational spectroscopy in protein research, providing researchers with clear, practical guidance on methods employed, areas of application, and modes of analysis. With chapter contributions from international leaders in the field, the book addresses basic principles of vibrational spectroscopy in protein research, instrumentation and technologies available, sampling methods, quantitative analysis, origin of group frequencies, and qualitative interpretation. In addition to discussing vibrational spectroscopy for the analysis of purified proteins, chapter authors also examine its use in studying complex protein systems, including protein aggregates, fibrous proteins, membrane proteins and protein assemblies. Emphasis throughout the book is placed on applications in human tissue, cell development, and disease analysis, with chapters dedicated to studies of molecular changes that occur during disease progression, as well as identifying changes in tissues and cells in disease studies.

    • Protein Homeostasis Diseases

      • 1st Edition
      • February 13, 2020
      • Angel L. Pey
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 1 3 2 3
      • eBook
        9 7 8 0 1 2 8 1 9 1 3 3 0
      Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-functi... and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders.

    • Lignocellulosics

      • 1st Edition
      • March 14, 2020
      • Ilari Filpponen + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 0 7 7 5
      • eBook
        9 7 8 0 1 2 8 0 4 1 1 5 4
      Lignocellulosics: Renewable Feedstock for (Tailored) Functional Materials and Nanotechnology gives a comprehensive overview of recent advances in using lignocellulosic substrates in materials science and nanotechnology. The functionalization and processing of lignocellulosics are described via a number of examples that cover films, gels, sensors, pharmaceutics and energy storage. In addition to the research related to functional cellulose nanomaterials, there has been an increased interest in research on lignin and lignocellulosics. This book explains how utilizing biomaterials as a raw material allows ambitious reconstruction of smart materials that are green and multifunctional. As lignin as a valuable material has gained a lot of attention in the last few years, shifting from purely extraction and fundamental characterization, and now also focusing on the preparation of exciting materials, such as nanoparticles, readers will find this to be a comprehensive resource on the topic.

    • Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System

      • 2nd Edition
      • September 29, 2020
      • Z Jin + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 5 3 1 4
      • eBook
        9 7 8 0 1 2 8 2 2 7 6 2 6
      Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System: Biomaterials and Tissues, Second Edition reviews how a wide range of materials are modeled and applied. Chapters cover basic concepts for modeling of biomechanics and biotribology, the fundamentals of computational modeling of biomechanics in the musculoskeletal system, finite element modeling in the musculoskeletal system, computational modeling from a cells and tissues perspective, and computational modeling of the biomechanics and biotribology interactions, looking at complex joint structures. This book is a comprehensive resource for professionals in the biomedical market, materials scientists and biomechanical engineers, and academics in related fields. This important new edition provides an up-to-date overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application, including new content on novel technologies, biomorphic hydroxyapatite and more.

    • YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

      • 1st Edition
      • October 20, 2020
      • Benjamin Bonavida
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 9 0 9 6
      • eBook
        9 7 8 0 1 2 8 2 2 6 3 6 0
      YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic underlying mechanisms by which YY1 regulates its pro-cancerous activities. In addition, it also describes the role of YY1 in the regulation of tumor cell resistance to conventional chemo and immunotherapies and the important role of inhibiting YY1 in cancer. This book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in understanding further the role of YY1 in cancer.

    • Experimental Hydrodynamics of Fast-Floating Aquatic Animals

      • 1st Edition
      • June 12, 2020
      • Viktor V. Babenko
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 0 2 5 3
      • eBook
        9 7 8 0 1 2 8 2 2 6 2 8 5
      Experimental Hydrodynamics of Fast-Floating Aquatic Animals presents the latest research on the physiological, morphological and evolutionary factors in aquatic animal locomotion. Beginning with an overview on how to conduct experiments on swimming aquatic animals, assessing hydrodynamic forces, resistance and geometric parameters of animal bodies, the book then details how aquatic animals, such as fast-moving dolphins, can achieve high speeds without over-expelling their energy resources. It provides insights into investigations on how animals, including dolphins, sharks and swordfish can maneuver through water at high speeds, offering a natural model for improving human and technological underwater locomotion. This book is essential for researchers and practicing biologists interested in the study of aquatic animal locomotive physiology and its application to human technology. Advanced undergraduate and graduate students will also find this a helpful academic resource for further understanding animal hydrodynamics.

    • Personalized Computational Hemodynamics

      • 1st Edition
      • April 16, 2020
      • Yuri Vassilevski + 4 more
      • English
      • Paperback
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      • eBook
        9 7 8 0 1 2 8 1 5 6 5 4 4
      Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies.

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Biochemistry biophysics

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