Skip to main content

Protein Homeostasis Diseases

Mechanisms and Novel Therapies

  • 1st Edition - February 13, 2020
  • Editor: Angel L. Pey
  • Language: English
  • Paperback ISBN:
    9 7 8 - 0 - 1 2 - 8 1 9 1 3 2 - 3
  • eBook ISBN:
    9 7 8 - 0 - 1 2 - 8 1 9 1 3 3 - 0

Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein h… Read more

Protein Homeostasis Diseases

Purchase options

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code needed.

Image of books

Institutional subscription on ScienceDirect

Request a sales quote

Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-function, and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders.