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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Pore-Forming Toxins

      • 1st Edition
      • Volume 649
      • March 10, 2021
      • English
      • Hardback
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      • eBook
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      Pore Forming Toxins, Volume 649 in the Methods in Enzymology series continues the legacy of this premier serial with quality chapters authored by field leaders. Chapters in this new release include X-ray crystallography shines a light on pore-forming toxins, Giant unilamellar vesicles for studying activity of pore forming proteins, Combined applications of fluorescence spectroscopy and molecular dynamics simulations in studies of Diphtheria Toxin translocation domain, Biophysical approaches to study actinoporin-lipid interactions, Molecular basis for activation of Actinoporins by lipids, Engineered ClyA for detection of biological molecules, Pore-forming Toxins for the Size-Discrimination of Polymers and Biopolymers: Towards Biomolecules Sequencing, and much more.

    • Rare-earth element biochemistry: Methanol dehydrogenases and lanthanide biology

      • 1st Edition
      • Volume 650
      • April 15, 2021
      • English
      • Hardback
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      • eBook
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      Methods in Enzymology, Volume 650 continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Biophysical methods to study lanthanide-protein interactions, Genetically encoded sensors to study lanthanide biology, Spectrophotometric methods to determine the stability constants of lanthanide-macromole... complexes, Lanthanide-based probes for amino acid modifications, In vitro selection and application of lanthanide-dependent DNAzymes, LRET biosensors for imaging protein interactions in living cells, Synthetic Modeling of the Structure and Function of the Lanthanide-Dependent... MDH Cofactor, EPR spectroscopy of lanthanides, Macromolecular crystallography for f-element complex characterization, and much more.

    • Carcinogen-Driven Mouse Models of Oncogenesis

      • 1st Edition
      • Volume 163
      • March 26, 2021
      • English
      • Hardback
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      • eBook
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      Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthr... Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-i... fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more. Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-i... liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induc... lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.

    • Recombinant Protein Expression: Eukaryotic hosts

      • 1st Edition
      • Volume 660
      • November 4, 2021
      • English
      • Hardback
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      • eBook
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      Recombinant Protein Expression, Part B, Volume 660 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on Multiplexed analysis protein: Protein interactions of polypeptides translated in Leishmania cell-free system, MultiBac system and its applications, performance and recent, Production of antibodies in Shuffle, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to enhance transcription in yeast, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to deregulate transcription in yeast, Antibody or protein-based vaccine production in plants, Cell-free protein synthesis, Plant-based expression of biologic drugs, and much more. Additional sections cover the Use of native mass spectrometry to guide detergent-based rescue of non-native oligomerization by recombinant proteins, Advancing overexpression and purification of recombinant proteins by pilot optimization through tandem affinity-buffer exchange chromatography online with native mass spectrometry, Method for High-Efficiency Fed-batch cultures of recombinant Escherichia coli, Method to transfer Chinese hamster ovary (CHO) shake flask experiments to the ambr® 250, and Expression of recombinant antibodies in Leishmania tarentolae.

    • Monitoring Vesicular Trafficking in Cellular Responses to Stress - Part B

      • 1st Edition
      • Volume 165
      • July 24, 2021
      • English
      • Hardback
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      • eBook
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      Monitoring Vesicular Trafficking in Cellular Responses to Stress - Part B, Volume 165 in the Methods in Cell Biology series, highlights new advances in the field, with this new release presenting coverage of different topics, including A novel tool for detecting lysosomal membrane permeabilization by high-throughput fluorescence microscopy, Exploring selective autophagy in Drosophila, Assessment of EGFP-Q74 degradation for the measurement of autophagic flux, Multimodal assessment of autophagy in mammalian cells with a novel, LC3-based tandem reporter, Multiplex quantification of autophagic flux by imaging flow cytometry, Monitoring autophagic flux in Caenorhabditis elegans using p62/SQST-1 reporters, High throughput screening for autophagy, and much more.

    • Ion Channels: Channel Biochemistry, Reconstitution, and Function

      • 1st Edition
      • Volume 652
      • May 29, 2021
      • English
      • Hardback
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      • eBook
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      Ion Channels Part A, Volume 651 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of new developments on the topic. Each chapter is written by an international board of authors.

    • Advances in Genetics

      • 1st Edition
      • Volume 108
      • November 16, 2021
      • Dhavendra Kumar
      • English
      • Hardback
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      • eBook
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      Advances in Genetics, Volume 108 provides the latest information on genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, with this new release including chapters on Clinical applications of cancer genetics and genomics, Epigenetic mutations in childhood tumors- the paradigm of Wilms tumor, Preventive population genomics-the model of BRCA related cancers, Recent advances of PARP inhibitors in medical oncology, Role of single cell and liquid biopsy in cancer research and clinical applications. Other chapters cover Recent advances and clinical utility of prostate cancer genomics, Recent advances in lung cancer genomics- applications in targeted therapy, and more.

    • Androgens in Women: Too Much, Too Little, Just Right, An Issue of Endocrinology and Metabolism Clinics of North America

      • 1st Edition
      • Volume 50-1
      • January 29, 2021
      • Margaret E. Wierman
      • English
      • Hardback
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      • eBook
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      Guest edited by Dr. Margaret E. Wierman, this issue of Endocrinology and Metabolism Clinics will cover several key areas of interest related to Androgens in Women. This issue is one of four selected each year by our series Consulting Editor, Dr. Adriana Ioachimescu. Articles in this issue include but are not limited to: Hyperandrogenic Anovulation: Differential Diagnosis and Evaluation, Diagnosis of Polycystic Ovary Syndrome, Polycystic Ovary Syndrome: Ontogeny in Adolescence, Fertility Issues in Polycystic Ovarian Disease: A Systematic Approach, Management of Women with PCOS during Pregnancy, Genetics of PCOS, Cardiometabolic Risk in PCOS: Current Guidelines, Non Classical Congenital Adrenal Hyperplasia, Post-menopausal Hyperandrogenism: Evaluation and Treatment Strategies, Sexual Dysfunction in Women, Use of Testosterone in Postmenopausal women, Risks of Testosterone Therapy in Women, Non-Classic Congenital Adrenal Hyperplasia, and more.

    • Protein Kinases in Drug Discovery

      • 1st Edition
      • Volume 124
      • February 22, 2021
      • Rossen Donev
      • English
      • Hardback
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      • eBook
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      Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by chemically adding phosphate groups to them. New chapters in this release include Transport Proteins and AMPs: Implications in Human Disease, Protein kinase CK2 inhibition as a pharmacological strategy, Emerging role of Protein kinase in diabetes mellitus: From Mechanism to therapy, Dual Roles of ATP-binding site in Protein Kinases: Orthosteric inhibition and Allosteric Regulation, Pseudokinases in drug discovery and development: progress, challenges and future prospects, Comparison of knowledge-based vs. combinatorial peptide library approaches for the identification of protein kinase substrates, and more.

    • Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C

      • 1st Edition
      • Volume 183
      • October 14, 2021
      • English
      • Hardback
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      • eBook
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      Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more.

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