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Elsevier

Academic Press

  • Cancer Biomarkers and Oncoviruses

    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Cancer Biomarkers and Oncoviruses examines the extensive clinical applications of biomarkers in cancer research, with a particular focus on oncoviruses. The book explores key topics such as cancer risk assessment, screening, and early detection. It further covers accurate diagnosis, patient prognosis, prediction of response to therapy, and cancer surveillance and monitoring. In 47 detailed chapters, Cancer Biomarkers and Oncoviruses presents the molecular biology and pathogenesis of viral oncology, the mechanisms of viral oncogenesis in humans, signaling pathways, and therapeutic options such as vaccines. It also discusses the future of cancer therapy involving oncoviruses.The present book also covers critical analyses of cost savings in healthcare, respiratory biomarkers in viral infections, and lessons learned from the COVID-19 pandemic, focusing on pandemic preparedness, early detection, surveillance, and response strategies. These discussions aim to provide valuable insights into how lessons from the pandemic can be applied to improve healthcare systems and response strategies for both viral infections and cancer, helping inform future health management practices.This book is an invaluable resource for health professionals, scientists, researchers, health practitioners, students, and anyone seeking to deepen their understanding in the field of cancer and virology. It offers valuable state-of-the-art insights, incorporating the latest research and cutting-edge developments in the field.

  • Strategic Disconnections in Retrosynthetic Analysis from Pattern Recognition

    An Applied Approach
    • 1st Edition
    • Claudio Trombini
    • English
    Strategic Disconnections in Retrosynthetic Analysis from Pattern Recognition: An Applied Approach introduces retrosynthetic analysis through strategic disconnection methods. It prioritizes disconnections of general structures characterized by specific functionalization patterns or structural motifs like stereogenic centers or bicyclic frameworks. Numerous examples from carefully selected literature illustrate each strategic disconnection, organized by functional or structural pattern, selected disconnection, and polar, radical, or concerted reaction pathways. Developing a deep understanding of these examples enhances 3D visualization skills, critical reasoning, and expertise in synthetic strategies.The book offers insights into advancements in organic synthesis over the last 50 years, with cases of varying complexity from curated literature. Readers can focus on examples that align with their interests or lab work, each case referenced for easy access to primary information. It is ideal for graduate and postdoc students in organic chemistry and synthesis and researchers in industry. Advanced undergraduate students with a solid organic chemistry foundation may also find it beneficial.

  • Insights into Migraine Treatments

    Towards Personalized Medicine
    • 1st Edition
    • Massimo Filippi + 1 more
    • English
    Insights into Migraine Treatments offers a comprehensive overview to guide the selection of the most appropriate therapy for each patient within the landscape of migraine care. It explores the full spectrum of available treatments and their mechanisms of action, while addressing the challenges of individualized therapeutic decision-making. By presenting essential data on efficacy, safety, and biomarkers of treatment response, this book serves as a practical resource for tailoring interventions to patient-specific needs. With its solution-oriented approach, it is a valuable reference for clinicians and researchers striving to advance migraine management.Covering topics from the clinical characteristics of migraine to acute therapies, pharmacological and nonpharmacological preventive strategies, and clinical, neuroimaging, and neurophysiological biomarkers, this book is designed to meet the complex and evolving needs of migraine patients.

  • Animal Models of Neurological Conditions

    A Reference Guide for Neuroscience Researchers and Trainees
    • 1st Edition
    • Jacob Raber
    • English
    Animal Models of Neurological Conditions informs about novel animal models and their unique strengths and limitations in the research of neurological conditions. It demonstrates the importance of animal models’ abilities to replicate only aspects of a given neurological condition and highlights the value of these animal models in increasing human brain function in afflicted patients. This book, comprised of thirteen chapters discusses various animal models and research methods for mental health, neurodevelopmental disorders, addiction, age-related neurodegenerative conditions, and viruses affecting brain function. Although developed with neuroscience researchers and trainees involved in pre-clinical and clinical research in mind, neurologists and other treatment professionals caring for patients with neurological conditions will also find value in this detailed resource.This is an invaluable resource for neuroscience researchers, trainees, and healthcare professionals.

  • Neuromonitoring Techniques

    Quick Guide for Clinicians and Residents
    • 2nd Edition
    • Hemanshu Prabhakar
    • English
    Neuromonitoring Techniques: Quick Guide for Clinicians and Residents, Second Edition continues to be the comprehensive resource designed to equip healthcare professionals with essential knowledge for effective patient care. This revised edition introduces new chapters that delve into cutting-edge areas of neuromonitoring, including Clinical Neuromonitoring, providing insights into real-world applications, Electroencephalogram... unraveling the intricacies of brain activity monitoring, and Brain Ultrasound, exploring the latest advancements in non-invasive imaging techniques. From the fundamentals in the Introduction to Neuromonitoring Techniques to advanced topics such as Cognitive Function Monitoring and Functional Neuroimaging, each chapter is precisely crafted to offer a quick yet thorough understanding of the respective techniques. Whether you are a seasoned clinician seeking to stay abreast of the latest advancements or a resident looking to build a strong foundation, this revised edition provides an accessible guide to the diverse realm of neuromonitoring.

  • An Introduction to Synoptic-Dynamic Meteorology

    • 1st Edition
    • Gabriel Williams
    • English
    An Introduction to Synoptic-Dynamic Meteorology offers a systematic exploration of synoptic meteorology, beginning with the basics of atmospheric pressure and atmospheric motion. It progresses into weather instrumentation and observation, analysis of these observations, surface fronts, and fundamental and inertial atmospheric forces. Subsequent chapters focus on balance in synoptic-scale flow, upper-tropospheric jet streams, and troughs and ridges. Concluding chapters address lower-Tropospheric Processes and Midlatitude Cyclones. This textbook serves as a bridge between introductory and upper-division atmospheric dynamics courses. Supplementary resources include a solutions manual and PowerPoint slides for instructors and Python notebooks with worked examples for both students and instructors.This book is essential for sophomore-level meteorology students, advanced researchers in atmospheric science, and professionals such as meteorologists, weather forecasters, and climate scientists. It is also beneficial for environmental consultants, aviation professionals, hydrologists, oceanographers, energy sector experts, and emergency management officials, making it a versatile resource in navigating the complexities of atmospheric science.

  • Organic Laboratory Experiments of the Future

    Doing Chemistry in Water
    • 1st Edition
    • Bruce H. Lipshutz + 1 more
    • English
    This lab manual offers students the opportunity to learn organic chemistry through a green chemistry lens, resulting in a more sustainable, future-looking course. Lipshutz and Muchalski’s Organic Laboratory Experiments of the Future: Doing Chemistry in Water approaches the subject with experiments, diagrams, and illustrations shaped by student feedback and honed through years of research and laboratory experience.Organic Laboratory Experiments of the Future: Doing Chemistry in Water includes material on reactions run in water, including but not limited to: ppm Pd-catalyzed couplings, SNAr reactions, nitro group reductions, enzyme-catalyzed reactions, catalytic hydrogenation of olefins, olefin metathesis, reductive aminations, and chemoenzymatic sequences. This lab manual is ideal for courses in organic chemistry, biochemistry, sustainable and green chemistry, and environmentally-resp... lab courses.

  • The Marmoset Brain in Stereotaxic Coordinates

    • 2nd Edition
    • George Paxinos + 3 more
    • English
    The first edition of The Marmoset Brain in Stereotaxic Coordinates (2012) was fundamental in the rapid establishment of this species as the preferred non-human primate in neuroscience research, with the atlas delineations having been adopted by all major projects using marmosets. Now, the second edition gives us the opportunity to capture 14 years of progress and introduce major enhancements:What is new in the 2nd Edition?For the first time sagittal and horizontal planes are included based on the computational average of 20 brains.For the first time cortical layers are identified.For the first time major divisions of the white matter are identified on the basis of Marmoset Brain Mapping Project (https://marmosetbra... (Liu et al., 2020).Cortical and subcortical delineations are thoroughly updated to reflect advances over the last 14 years.

  • Genetic Testing in Breast Cancer

    Innovations in Diagnosis and Treatment
    • 1st Edition
    • Manzoor Ahmad Mir
    • English
    Genetic Testing in Breast Cancer: Innovations in Diagnosis and Treatment addresses the urgent need for novel, minimally invasive diagnostic techniques to accurately identify breast cancer early and monitor treatment efficacy, focusing particularly on triple-negative breast cancer (TNBC). This comprehensive volume analyzes the latest research and developments in genetic testing, covering strategies like next-generation sequencing and the Sanger method. It highlights their potential to revolutionize early diagnosis and personalized treatment plans. The book also discusses challenges and opportunities, providing insights into hereditary mutations, genetic counseling, and clinical practice integration.Serving as a valuable resource for students, researchers, oncologists, pharmacologists, and healthcare professionals, it includes preclinical and clinical case studies that illustrate the practical applications of genetic testing for various breast cancer subtypes, including TNBC and HER2-positive breast cancer. The editors aim to advance treatment and improve patient outcomes through cutting-edge genetic testing techniques.

  • Reconstructive Transplantation and Regenerative Surgery

    The New Frontier
    • 1st Edition
    • Volume 3
    • Vijay Gorantla + 2 more
    • English
    Reconstructive Transplantation and Regenerative Surgery: The New Frontier is the third volume in the Regenerative and Transplant Medicine Series. This volume captures a decade of transformative progress at the intersection of reconstructive transplantation, regenerative medicine, and tissue engineering—fields that have begun to converge into a bold new frontier: regenerative surgery. Coedited by internationally recognized leaders in the field, this authoritative work explores cutting-edge advances that are redefining the possibilities for patients with complex tissue loss and functional deficits.Through comprehensive and original chapters written by global experts, this book charts the latest innovations in vascularized composite allotransplantation (VCA), graft immunomodulation, neurogeneration and diagnostics, ischemia mitigation and tissue preservation, and tissue engineering and biomaterials.Compreh... in scope and visionary in approach, Reconstructive Transplantation and Regenerative Surgery: The New Frontier is an essential resource for surgeons, researchers, biomedical engineers, and clinicians.

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