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Elsevier

Academic Press

  • The Resistance of Cervical Cancer to Chemotherapy and its Reversal

    • 1st Edition
    • Volume 9
    • S. Muthusami
    • English
    The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers.In 10 chapters, this book first provides an introduction and history of cervical cancer; next, it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists, and clinicians interested in building a comprehensive understanding of the field.

  • Innovations in the Blue Economy

    Sustainable Practices in Marine Macro- and Microalgae Cultivation
    • 1st Edition
    • José Carlos Magalhães Pires
    • English
    Innovations in the Blue Economy: Sustainable Practices in Marine Macro- and Microalgae Cultivation explores the latest technologies, advancements, and ongoing research surrounding the sustainable cultivation of microalgae and seaweed. Cultivation strategies, challenges, applications, products, and regulatory considerations are covered through an interdisciplinary lens to provide readers with a holistic understanding. Written by a globally diverse network of experts, the book is systematically structured to be accessible to readers across multiple sectors. Chapters describe the biology, diversity, and vital ecological roles of various microalgal and seaweed species and explore differing cultivation systems, emphasizing the critical aspects of site selection and ecosystem compatibility. Cultivation strategies are also described and illustrated through applied case studies that showcase successful large-scale cultivation initiatives. Final chapters consider regulatory landscapes and multifaceted hurdles to sustainable industry scale-up and provide innovative solutions and research gaps for industry consideration. This is an essential read for algal aquaculturists, bioengineers, and students of marine biology and biotechnology.

  • Performance Evaluation and Attribution Volume One

    Asset Pricing and Models
    • 2nd Edition
    • Russ Wermers + 2 more
    • English
    This Second Edition of Performance Evaluation and Attribution Volume One: Asset Pricing and Models, presents an updated, comprehensive exploration of portfolio performance evaluation. Based on the authors’ Performance Evaluation and Attribution of Security Portfolios (2012), this volume of the second edition adds four new chapters and updated content throughout in its practical approach to measuring manager skills and using recent statistical techniques to solve investment problems. Added are new factor models, including the newly developed q-factor model, new examples, and new work on qualitative considerations that can be used in identifying skilled fund managers. This highly detailed new edition combines academic rigor with insights and guidance for real-world applications of diverse approaches to identifying skilled professional portfolio managers

  • Advancing Early Diagnosis in Chronic Diseases

    Tools, Techniques, and Technologies
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Advancing Early Diagnosis in Chronic Diseases: Tools, Techniques, and Technologies explores the transformative potential of early detection strategies and technologies in reshaping chronic disease outcomes. Addressing the urgent need for innovative approaches for managing conditions such as cardiovascular diseases, diabetes, cancer, neurodegenerative disorders, and pediatric, chronic conditions, this book underscores the importance of timely interventions to reduce disease burden. The book provides a comprehensive overview of cutting-edge tools, including predictive biomarkers, artificial intelligence, genomic and proteomic screening, wearable health devices, digital twins, and point-of-care testing. Readers will gain insights into how these advancements revolutionize early diagnosis and personalized treatment.Written by experts from interdisciplinary fields, the book bridges the gap between scientific discovery and clinical application, addressing challenges such as knowledge gaps, integration barriers, and accessibility of diagnostic innovations. It covers a broad spectrum of chronic conditions, including metabolic, inflammatory, respiratory, renal, hepatic, and neurodegenerative diseases, with added focus on pediatric patients and early detection in childhood disorders.

  • Clinical Diseases, Production, and Management of Cattle

    • 1st Edition
    • Tanmoy Rana
    • English
    Clinical Diseases, Production, and Management of Cattle is an essential reference that extensively covers the health, care, and management of cattle. This comprehensive guide begins with general considerations of cattle care and production, progresses into specific practices for calf care, and culminates in a broad examination of cattle diseases—from common to rare, mild to severe. The book includes preventative measures, diagnostic procedures, and treatments for diseases. It is an invaluable resource for industry professionals, animal agriculture researchers, and veterinarians looking to deepen their understanding of cattle health and disease prevention.

  • Mathematical Concepts and Methods in Modern Biology

    Using Modern Discrete Models
    • 2nd Edition
    • Raina Robeva
    • English
    Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models, Second Edition presents an updated, quantitative framework for analyzing, predicting, and modulating complex biological systems. Structured around project-based learning and problem-solving, it integrates essential mathematical concepts and methods in the context of key biological questions. Topics include gene regulatory and neuronal networks, CpG islands, plant population growth, interacting populations, phylogenetics, and phylogenomics. Modeling tools span discrete dynamical systems (including deterministic and stochastic Boolean networks), ordinary differential equations, projection matrices, agent-based modeling, polynomial ideals, Gröbner bases, tropical algebra, and other algebraic approaches. Computation is supported by a range of software tools, including some developed for this book, as well as open source, freely available, and proprietary platforms. Updated code examples and step-by-step instructions illustrate software use, making this a valuable resource for health professionals, scientists, researchers, and students in related fields.

  • Epigenetic Regulations in Gastrointestinal Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 1 more
    • English
    Epigenetic Regulations in Gastrointestinal Cancers offers a comprehensive exploration of the genomic and epigenomic alterations that underpin the aggressive nature of gastrointestinal (GI) cancers. . By synthesizing the latest research and insights into the role of the tumor microenvironment and cellular signaling pathways, this book aims to elucidate the multifaceted nature of GI cancer neoplasia and propose innovative therapeutic strategies. Addressing critical challenges in GI cancer research and treatment, this book serves as a vital resource for researchers and clinicians striving to bridge the gap between basic research and clinical application. It tackles the complexities of GI cancer mechanisms by integrating knowledge from diverse fields, thereby providing a holistic understanding essential for effective therapeutic development. Through real-world case studies and expert contributions, the book highlights successful treatment regimens that leverage epigenetic insights, thereby fostering dialogue among multidisciplinary teams and promoting collaborative approaches to cancer care. Moreover, the book emphasizes the importance of staying abreast of rapid advancements in the field of cancer research. With contributions from leading experts and an accompanying online platform featuring interactive resources, readers will have access to the latest insights and developments in GI cancer research. By identifying specific epigenetic targets and innovative strategies for overcoming treatment resistance, this book aspires to enhance patient outcomes in GI cancers and contribute to the ongoing evolution of personalized medicine in oncology.

  • Cell Shape and Position during Development

    • 1st Edition
    • Volume 166
    • English
    Cell Shape and Position during Development, Volume 166 provides a comprehensive overview of the fundamental roles that cell morphology and spatial organization play in the development of multicellular organisms. This volume brings together leading experts in developmental biology, cell biology, and biophysics to explore how cells acquire specific shapes. Chapters in this new release include Cell shape changes during sperm-egg interactions, Cell shape and position during organ development, Regulation of shape and position during asymmetric cell division, Cell shape dynamics during mouse peri-implantation development and embryo dormancy, Shaping the intestine: the role of cell morphology and spatial dynamics in development, and more.Additional sections Intermediate filaments in cell shape and position, Regulation of adult stem cell behavior by cytoskeletal dynamics and cell shape, Shape changes in gastrulation, and more.

  • Digital Twins of Advanced Materials Processing

    • 1st Edition
    • Tarasankar DebRoy + 1 more
    • English
    Digital twins represent an emerging technology of immense potential across various industries. Their significance is particularly pronounced within Industry 4.0 and smart manufacturing paradigms, which strive to elevate efficiency and quality through seamless digital integration. By amassing and scrutinizing extensive data streams, digital twins empower data-centric decision-making—a pivotal asset in contemporary industry. Digital Twins of Advanced Materials Processing bridges the gap in comprehensive resources concerning advanced materials processing, a domain characterized by rapid evolution. It provides pragmatic remedies and real-world case studies, catering to tangible implementation needs. Moreover, digital twins hold the capacity to amplify efficiency and innovation within materials processing—a perspective deeply explored within this book, rendering it invaluable for professionals, researchers, and students alike. The prospects of employing digital twins in materials processing span diverse horizons: refining materials innovation, streamlining processes, enabling data-driven maintenance, enhancing product quality, and unearthing insights rooted in data. The book also undertakes the challenge of addressing key issues encompassing data amalgamation and integrity, model validation and calibration, software and data safeguarding, scalability, and cost considerations.

  • Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments

    • 1st Edition
    • Tuan Anh Nguyen + 2 more
    • English
    Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments provides a balanced exploration of the dual roles of nanotechnologies in oncology. Structured in four parts, the book begins with foundational knowledge of nanovaccines and nanomedicines, detailing their applications in cancer care and highlighting their precision in targeting cancer cells while reducing systemic toxicity. Importantly, the book addresses potential drawbacks, discussing side effects and safety concerns associated with these innovations. The final section emphasizes ethical, regulatory, and safety challenges, underscoring the need for careful oversight as nanotechnologies advance.For the academic audience, this book serves as a vital resource, offering insights that equip researchers and healthcare professionals to make informed decisions regarding clinical applications. Its focus on both benefits and risks, alongside forward-looking perspectives, ensures that readers are well-prepared for future developments in the field of nanomedicine and cancer therapy.

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