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Academic Press

  • Fundamentals and Therapeutic Applications of Liposomes

    • 1st Edition
    • December 4, 2025
    • Prashant Kesharwani
    • English
    Fundamentals and Therapeutic Applications of Liposomes provides an in-depth exploration of liposomal delivery systems for therapeutic purposes. This comprehensive book covers the synthesis and scaling up of liposomes for clinical use, examining their diverse applications in cancer therapy, immunotherapy, gene delivery, wound healing, viral disease, and neurological disorders. It also summarizes the regulatory aspects associated with clinical translation and industrial production. The book addresses the toxicity, safety, and environmental considerations of using liposomes for therapeutics, making it a useful resource for researchers, academics, and R&D groups interested in the development, production, and application of liposomes in various therapeutic settings.

  • Stem Cells and Tissue Regeneration

    Bridging Research and Clinical Practice
    • 1st Edition
    • December 4, 2025
    • Wen Zeng + 2 more
    • English
    Stem Cells and Tissue Regeneration: Bridging Research and Clinical Practice delves into the latest advancements in the dynamic field of tissue regeneration. This comprehensive book begins with an introduction that reviews stem cell classifications, characteristics, functions, and their integral relationship with tissue regeneration. This first section offers readers a solid foundation and understanding of the book’s scope and significance in contemporary research and clinical applications. Subsequent chapters explore each major organ, including skeletal muscle regeneration and vascular organoids.Additional... the book presents innovative strategies and methods for research, culminating in a forward-looking perspective on the future of tissue regeneration. Authored by experts, it serves as a vital resource for researchers, clinicians, and surgeons involved in tissue repair.

  • Drug Metabolism in Diseases

    Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development
    • 2nd Edition
    • December 4, 2025
    • Wen Xie
    • English
    Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development, Second Edition provides essential knowledge for pharmaceutical scientists and biologists to understand the interplay between diseases and physiological conditions, impacting drug metabolism and its implications in personalized treatment. Expanded with six new chapters since the first edition, this updated book covers the latest scientific findings. Other important points include the book’s comprehensive reference on mutual effects between drug metabolism and diseases, implications in precision medicine, and therapeutic development. Pharmaceutical scientists, drug metabolism researchers, and research physicians will benefit from the expert insights provided.

  • Endotoxin in Critical Illness

    • 1st Edition
    • December 4, 2025
    • John Kellum + 1 more
    • English
    Endotoxin in Critical Illness intricately explores the theme of endotoxin and sepsis through the lenses of basic, clinical, and translational science. This work consolidates and synthesizes novel clinical insights and groundbreaking scientific discoveries into one comprehensive resource on endotoxic septic shock and sheds light on cutting-edge approaches in treatment. Beginning with a historical journey, the book traces the evolution of understanding from ancient concepts to modern molecular insights. It covers the physiological aspects of endotoxin sensitivity, tolerance, and human response variation. The crucial role of the gut microbiome in critical illness serves as a translational link between foundational science and clinical implications, and the complex language of bacterial communication is introduced, merging basic science with potential translational applications. In the clinical arena, chapters cover the critical role of endotoxin in septic shock, trauma, and its relevance in COVID-19, providing a translational bridge between laboratory findings and real-world clinical scenarios. The historical context of anti-endotoxin drug development is revisited, emphasizing the translational challenges faced in bridging basic science discoveries to clinical applications. The discussion on quantifying endotoxin concentration as well as the exploration of therapeutic rationale and clinical experiences with endotoxin removal therapy serve as a culmination of basic understanding translated into practical applications. The book concludes by contemplating the complexity of sepsis and acknowledging the challenges in achieving personalized medicine and underscoring the dynamic nature of the translational journey. In essence, this comprehensive exploration provides clinicians, researchers, and scientists with a holistic understanding of endotoxin and sepsis and potential advancements in patient care.

  • Harnessing Endogenous Mechanisms for Targeted Drug Delivery

    • 1st Edition
    • December 4, 2025
    • Anisha A. D’Souza + 2 more
    • English
    Harnessing Endogenous Mechanisms for Targeted Drug Delivery presents a comprehensive exploration of the evolving landscape of targeted drug delivery, emphasizing the strategic utilization of the body's intrinsic biological pathways. This authoritative two-volume reference addresses the critical need for precision in therapeutic delivery, overcoming physiological, anatomical, and immunological barriers through innovative endogenous mechanisms. By integrating foundational concepts with advanced methodologies, the work underscores the transition from traditional passive and active targeting to sophisticated endogenous strategies that enhance drug specificity and efficacy.The text systematically examines the multifaceted challenges inherent in drug delivery, including detailed analyses of in vivo barriers such as the blood-tumor barrier, blood-brain barrier, ocular, pulmonary, and gastrointestinal obstacles, as well as cellular and intracellular impediments. It further elucidates endogenous stimuli-responsive systems, nutrient transporter exploitation, glyco-targeting, and stealth peptide modifications. Comprehensive coverage extends to drug conjugates, protein corona phenomena, and cell-based delivery platforms encompassing stem cells, leukocytes, erythrocytes, and platelets. The series also addresses extracellular vesicles, viral vectors, and plant virus-based carriers, culminating in critical discussions on manufacturing complexities, regulatory considerations, and clinical translation challenges.This definitive resource is indispensable for graduate students, postdoctoral researchers, and professionals in academia and industry engaged in targeted drug delivery research and development. By providing an in-depth understanding of endogenous targeting mechanisms and their translational potential, the book fosters innovation and supports the advancement of precision therapeutics with the goal of improving patient outcomes.

  • Microbial Stress Survival

    • 1st Edition
    • December 4, 2025
    • Ashutosh Kumar
    • English
    Microbial Stress Survival explores the diversity of microbes, the microbe-host relationship, and the various strategies employed by microbes that enable them to adapt to stressful environments and persist in hostile conditions. The book aims to cover critical pathogen biology, microbial adaptation and survival strategies, and the impact of microbial resilience on therapeutic efforts. Topics include the modulation of host pathways by pathogens for their adaptation and survival; their drug tolerance and antimicrobial resistance; role of proteins in microbial stress survival; and evolutionary adaptative mechanisms of extremophiles. Microbial Stress Survival is an insightful resource for those interested in pathogen biology and the different adaptive features and resilience of microbes.

  • Redox Catalysis for Energy and the Environment

    • 1st Edition
    • Volume 77
    • December 3, 2025
    • English
    Redox Catalysis for Energy and The Environment, Volume 77 in the Advances in Catalysis series highlights new advances in the field, with this volume presenting engaging chapters written by an international board of authors. Topics covered include the development of earth-abundant molecular catalysts with redox-active ligands for artificial photosynthesis, the use of porous organic materials for photocatalytic degradation of water pollutants, supramolecular systems for chemical energy conversion, and dyadic systems for water-splitting catalysis. The volume also explores innovations in artificial photosynthesis extending beyond water splitting, aimed at applications in organic synthesis.

  • Diabetes and Neurodegeneration

    • 1st Edition
    • December 3, 2025
    • Debasis Bagchi + 2 more
    • English
    Diabetes and Neurodegeneration unlocks the complex interplay between diabetes and Neurodegeneration, reviewing the relationship between these two prevalent health challenges. This book begins with a simple guide to understanding high blood sugar, tracing the historical milestones of hyperglycemia, and unveiling the primary factors that contribute to diabetes development, from genetic predisposition to lifestyle hazards. The second section aims to bridge the gap between diabetes and dementia, presenting early clinical evidence, case studies, and susceptibility assessments that underscore the strong link between hyperglycemia and neurodegeneration. Biomarkers and pathways connecting these conditions are explored, including the role of Advanced Glycated End (AGE) products and their implications in protein misfolding and aggregation. The narrative extends to therapeutic strategies, evaluating the efficacy of antidiabetic drugs, targeting insulin resistance, and introducing novel interventions to arrest amyloid-associated pathogenesis. This comprehensive guide provides both clinicians and researchers with a thorough understanding of the intricate link between diabetes and neurodegeneration.

  • Photovoltaic Device Physics and Materials

    Solar Cell, Photovoltronic, and Sensor Structures
    • 3rd Edition
    • December 3, 2025
    • Stephen J. Fonash
    • English
    Photovoltaic Device Physics and Materials: Solar Cell, Energy Management, and Retinomorphic Structures, Third Edition reflects that the physics behind these three important photovoltaics applications is the same while the device structure, designs, and materials used to optimally implement this physics varies. These variations come from differences in the incoming spectra, the materials utilized, and differences in the concomitant light trapping required. The importance of the materials utilized requires extensive examination and exploration of emerging inorganics, including perovskites, organics, and 2-D materials.An additional consideration that is addressed is device planar extent, which varies with device application. This thoroughly revised and expanded text is a valuable resource for students and researchers looking to learn about photovoltaic or solar cell devices, as well as faculty, engineers, R&D, government and industry labs, and medical facilities.

  • One Planet, One Health, One Future

    Charting a Course for Global Wellness, Environmental Resilience, and Sustainable Food Systems
    • 1st Edition
    • December 3, 2025
    • Ranbir Chander Sobti + 4 more
    • English
    One Planet, One Health, One Future: Charting a Course for Global Wellness, Environmental Resilience, and Sustainable Food Systems provides a comprehensive synthesis of research findings, best practices, and emerging trends across the interconnected fields of health, environment, and agriculture, serving as a valuable reference for those seeking to deepen their understanding of interdisciplinary issues. Chapters explore topics such as precision public health, artificial intelligence in environmental monitoring, and regenerative agriculture practices. The book presents cutting-edge insights and innovative solutions that can inform and inspire the readers and contribute to advancing knowledge in their respective fields. Written by experts in diverse fields such as epidemiology, ecology, agronomy, and public health, the book offers multidimensional insights and perspectives for researchers, policymakers, and practitioners working at the intersection of public health, environmental science, and agricultural studies.

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