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Academic Press

  • AI Technologies for Crop Breeding

    • 1st Edition
    • Jen-Tsung Chen
    • English
    AI Technologies for Crop Breeding offers the latest insights into the use of artificial intelligence models to improve plant health and production. Presenting applications of AI technologies in plant biology, biotechnology, and crop breeding, it explores practices for the mitigation of biotic and abiotic stressors as well as other plant growth challenges.AI-based technologies are expected to advance approaches to plant functional genomics and multiple omics, resulting in smarter and more efficient crop breeding for next-generation agriculture helping to address the challenges of the increasing human population and the globally changing climate. AI tools such as machine learning, particularly deep learning, have been applied to predict chief players in complicated biological networks, increasing the understanding of in-depth mechanisms of plant-pathogen and plant-environment interactions. Additionally, responses of plants facing stress can be modeled using AI technologies, and the resulting data are valuable not only to plant stress physiology but also for stress-resilient and disease-resistant crop breeding.This book introduces AI technologies for studying plant biology, focusing on machine learning and deep learning models for integrating multiple omics approaches and revealing the knowledge of plant functional genomes. Technological advancements and emerging applications of machine learning and deep learning in genomic selection, genome-wide association study (GWAS), phenotyping and constructing phenomics, and transcriptomics are also featured in this book.AI Technologies for Crop Breeding is an ideal reference for researchers, academics, and advanced-level students and professors in the fields of plant sciences, plant stress physiology, bioinformatics, systems biology, and crop breeding.

  • Advancements in the Treatment and Prevention of Breast Cancer

    • 1st Edition
    • Dileep Kumar
    • English
    Advancements in the Treatment and Prevention of Breast Cancer highlights the significance of early detection, risk assessment, and comprehensive care in mitigating the burden of breast cancer within communities. It not only offers insights into the genetic basis of breast cancer susceptibility, familial risk assessment, and emerging genetic testing technologies but also empowers patients and their families with knowledge about available treatment options, clinical trials, and support resources.In 14 chapters this book provides an in-depth analysis of translational research focusing on understanding the etiology of breast cancer, elucidating potential avenues for primary prevention strategies. It offers a comprehensive overview of recent breakthroughs in understanding the molecular mechanisms underlying breast cancer development and discussing novel targeted treatment approaches derived from these advances but also discusses strategies for minimizing treatment-related toxicity in breast cancer management, including supportive care measures and personalized treatment approaches. This book is a valuable resource for anyone interested in the latest developments in breast cancer care and provides clear explanations of complex scientific topics and will offer insights that can help improve patient care and outcomes.

  • Ketamine

    Fundamentals, Applications, Pharmacology, and Clinical Aspects
    • 1st Edition
    • Albert Dahan + 1 more
    • English
    Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.

  • Data-Driven Diagnostics and Disease Prediction with AI Optimization

    • 1st Edition
    • Shailendra Pratap Singh + 3 more
    • English
    Data-Driven Diagnostics and Disease Prediction with AI Optimization provides useful insights into model creation, data preparation, and ethical issues for healthcare applications. The book covers all the conventional and non-conventional methods related to this domain. It also discusses AI-based optimization techniques, Machine Learning models, and Advanced AI, offering practical insights, case studies, and optimization strategies to help data scientists and researchers efficiently employ AI in diagnostics and illness prediction in a world where precise diagnostics and early illness prediction may save lives and healthcare resources.

  • Artificial Metalloproteins

    • 1st Edition
    • Volume 720
    • English
    Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.

  • Elementary Real Analysis

    A Practical Introduction
    • 1st Edition
    • Thomas Bieske
    • English
    Elementary Real Analysis: A Practical Introduction provides a robust foundation for success in real analysis, presenting traditional material in an accessible, engaging manner with the support of clearly outlined learning objectives and exercises.Organized into two well-designed sections, the book begins with a comprehensive review of prerequisite knowledge. Section I includes chapters such as “Sets,” “Properties of Real Numbers,” “Properties of Integers,” and “Functions and Relations,” each accompanied by a wealth of exercises that encourage exploration and practice. These chapters lay the foundation for the second section which delves into advanced topics such as sequences, continuity, and differentiation, culminating in a synthesis of concepts that prepares students for further study of mathematical analysis. For easy reference, two appendices entitled “Mathematical Statements” and “Proof Methods” provide the reader with an accessible reference to the essential language and techniques of proof writing.Whether used in a classroom or for self-directed learning, Elementary Real Analysis: A Practical Introduction is a vital companion for students seeking an introduction to real analysis, bridging the gap between basic principles and advanced mathematical concepts with clarity and precision.

  • IoT Security

    Fundamentals and Key Enabling Technologies
    • 1st Edition
    • SK Hafizul Islam + 3 more
    • English
    IoT Security: Fundamentals and Key Enabling Technologies explores the complex interactions between Internet of Things (IoT) and the pressing need for effective cyber security solutions. Diving into real-world case studies to provide insights into implementing efficient security measures that safeguard against online dangers, this book comprehensively analyzes the challenges and possibilities presented by intelligent technologies fueling transformational change, emphasizing the crucial role cybersecurity plays in defending networks, data, and user privacy in an increasingly interconnected digital ecosystem.Coverage includes cryptographic methods, communication networks, device identity and access, data governance and privacy, as well as regulatory frameworks and standards for IoT security. Computer science researchers and engineers will benefit from this compilation of cutting-edge research and practical case studies, learning how to minimize risks for IoT and intelligent technologies.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 129
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Fungal and Protozoan Carbonic Anhydrases

    • 1st Edition
    • Volume 57
    • English
    Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.Additiona... chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.

  • Advanced Cancer Research Protocols

    • 1st Edition
    • Volume 198
    • English
    Advanced Cancer Research Protocols, Volume 198 is a comprehensive and cutting-edge resource dedicated to the latest methodologies and protocols in the field of cancer research. Topics in this new release include Introduction to Cancer Biology and Current Research Trends, Cell Culture Techniques for Cancer Research, Practical Approaches to Advanced Molecular Biology Techniques, High-throughput sequencing Technologies for Cancer Genomics, Epigenetic Analysis in Cancer Research, Proteomics and Metabolomics in Cancer Biomarker Discovery, In vivo Cancer Modeling Using Mouse Models, and much more.Other sections highlight advances in Advanced Imaging Techniques for Cancer Research, Cancer Stem Cell Analysis and Targeting, Immunotherapy and Cancer Vaccine Development, Gene Editing Techniques in Cancer Research, Single-Cell Analysis in Cancer Research, Liquid Biopsy and Circulating Tumor Cell Analysis, and Exploring the Tumor Microenvironment in Solid Cancer: From Biology to Therapy.

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