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Elsevier

Academic Press

  • Drug Repurposing in Cancer Therapy

    Approaches and Applications
    • 1st Edition
    • Kenneth K.W. To + 1 more
    • English
    Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.

  • Statistics and Probability in Forensic Anthropology

    • 1st Edition
    • Zuzana Obertová + 2 more
    • English
    Statistics and Probability in Forensic Anthropology provides a practical guide for forensic scientists, primarily anthropologists and pathologists, on how to design studies, how to choose and apply statistical approaches, and how to interpret statistical outcomes in the forensic practice. As with other forensic, medical and biological disciplines, statistics have become increasingly important in forensic anthropology and legal medicine, but there is not a single book, which specifically addresses the needs of forensic anthropologists in relation to the research undertaken in the field and the interpretation of research outcomes and case findings within the setting of legal proceedings. The book includes the application of both frequentist and Bayesian statistics in relation to topics relevant for the research and the interpretation of findings in forensic anthropology, as well as general chapters on study design and statistical approaches addressing measurement errors and reliability. Scientific terminology understandable to students and advanced practitioners of forensic anthropology, pathology and related disciplines is used throughout. Additionally, Statistics and Probability in Forensic Anthropology facilitates sufficient understanding of the statistical procedures and data interpretation based on statistical outcomes and models, which helps the reader confidently present their work within the forensic context, either in the form of case reports for legal purposes or as research publications for the scientific community.

  • Nanotechnology for Oral Drug Delivery

    From Concept to Applications
    • 1st Edition
    • João Pedro Martins + 1 more
    • English
    Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies.

  • Hormones and Synapse

    • 1st Edition
    • Volume 114
    • Gerald Litwack
    • English
    Hormones and Synapse, Volume 114 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including how growth hormone promotes synaptogenesis, sex hormones and proteins involved in brain plasticity, corticotropin releasing factor modulates excitatory synaptic transmission, bisphenol a and memory: a role for dendritic spines, brain insulin resistance impairs hippocampal synaptic plasticity, estradiol induces synaptic rearrangements, stress and remodeling of hippocampal spine synapses, neurotrophin-3 modulates synaptic transmission, nongenomic neurosteroid modulation of hippocampal dendritic spines, neural sex steroids and hippocampal synaptic plasticity, origin of chemical synapses, neural sex steroids and hippocampal synaptic plasticity, and much more.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 148
    • English
    Advances in Cancer Research, Volume 148, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

  • Transmutations, Singular and Fractional Differential Equations with Applications to Mathematical Physics

    • 1st Edition
    • Elina Shishkina + 1 more
    • English
    Transmutations, Singular and Fractional Differential Equations with Applications to Mathematical Physics connects difficult problems with similar more simple ones. The book's strategy works for differential and integral equations and systems and for many theoretical and applied problems in mathematics, mathematical physics, probability and statistics, applied computer science and numerical methods. In addition to being exposed to recent advances, readers learn to use transmutation methods not only as practical tools, but also as vehicles that deliver theoretical insights.

  • Up and Running with AutoCAD 2021

    2D and 3D Drawing, Design and Modeling
    • 1st Edition
    • Elliot J. Gindis + 1 more
    • English
    Up and Running with AutoCAD 2021: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instruction, examples and insightful explanations. The book emphasizes core concepts and practical application of AutoCAD in engineering, architecture and design. Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written with the user in mind by a long-time AutoCAD professional and instructor.

  • Policy Implications of Autonomous Vehicles

    • 1st Edition
    • Volume 5
    • English
    Policy Implications of Autonomous Vehicles, Volume Five in the Advances in Transport Policy and Planning series systematically reviews policy relevant implications of AVs and the associated possible policy responses, and discusses future avenues for policy making and research. It comprises 13 chapters discussing: (a) short-term implications of AVs for traffic flow, human-automated bus systems interaction, cyber-security and safety, cybersecurity certification and auditing, non-commuting journeys; (b) long-term implications of AVs for carbon dioxide (CO2) emissions and energy, health and well-being, data protection, ethics, governance; (c) implications of AVs for the maritime industry and urban deliveries; and (d) overall synthesis and conclusions.

  • Advances in Agronomy

    • 1st Edition
    • Volume 163
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 163, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Our Wired Nerves

    The Human Nerve Connectome
    • 1st Edition
    • Douglas W Zochodne
    • English
    The nervous system is a complex, sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: the central nervous system consisting of the brain and spinal cord and the peripheral nervous system. This consists of all other neural elements, including the peripheral nerves and the autonomic nerves. Peripheral nerves are the essential connections between the brain and spinal cord and the body. Without nerves there is no movement or sensation. Our Wired Nerves: The Human Nerve Connectome, reviews the essential anatomy and physiology of the peripheral nerve. It introduces the reader to what neuropathies are, how pain arises from damaged nerves and how nerves might be regenerated, including new and exciting ideas over how to coax their regrowth. Written by Dr. Douglas Zochodne leading expert in the field, and first book to focus on the Peripheral nerves it will surely be an essential reference for researchers and clinicians alike.

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