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Elsevier

Academic Press

  • Advances in Cancer Research

    • 1st Edition
    • Volume 160
    • English
    Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more.

  • Stem Cell in Medicine

    • 1st Edition
    • Volume 199
    • English
    **Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.

  • ZIP Metal Ion Transporters

    • 1st Edition
    • Volume 687
    • English
    ZIP Metal Ion Transporters, Volume 684 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Biochemistry, Biophysics and Structural Biology, Structure determination of a bacterial ZIP in lipidic cubic phase, Cell-based metal transport assay for animal and plant ZIPs, Measurement of metal binding affinity and transport activity in ZIP transporters using spectroscopic methods, Considerations in production of the (prokaryotic) ZIP family transporters for structural and functional studies, Metal-protein interactions investigated using model systems: thermodynamic, spectroscopic and computational methods, and more. Additional chapters cover Getting Zinc Into and Out of Cells, In-silico modeling of ZIP9 (TBD), Cellular Function and Regulation, Methods to visualize zinc transporter proteins of the SLC39A family in cells, Assessing metal ion transporting activity of ZIPs: intracellular zinc and iron detection, In vitro studies for studying manganese transport and homeostasis, and much more.

  • Metalloenzymes

    From Bench to Bedside
    • 1st Edition
    • Claudiu T. Supuran + 1 more
    • English
    Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications.

  • Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal

    • 1st Edition
    • Volume 2
    • English
    Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal presents in-depth content written by international experts in the study of resistance to anti-CD20 antibodies and approaches for their reversal. Anti-CD20 antibodies are used to achieve B cell depletion and are developed to treat B cell proliferative disorders, including non-Hodgkin’s lymphoma and chronic lymphocytic leukemia. In the past two decades, anti-CD20 antibodies have revolutionized the treatment of all B cell malignancies, however, there are patients that fail to respond to initial therapy or relapse sooner. This book explores new and existing avenues surrounding Anti-CD20 antibodies. In recent years, several next-generation anti-CD20 therapies have been developed but predicting and reversing resistance is still a challenging task. These areas are being actively studied as they represent a potential to improve anti-CD20 therapies and are discussed thoroughly in the book. It is a valuable resource for researchers, students and member of the biomedical and medical fields who want to learn more about resistance to anti-CD20 antibodies and their reversal.

  • Optimal Operation of Active Distribution Networks

    Congestion Management, Voltage Control and Service Restoration
    • 1st Edition
    • Feifan Shen + 4 more
    • English
    Optimal Operation of Active Distribution Networks: Congestion Management, Voltage Control and Service Restoration provides researchers and practitioners with a clear and modern understanding of how to optimize the economic, secure and resilient operation of active distribution networks. The book provides case studies, modern implementations and supporting flowcharts and code, along with current research in congestion management, service restoration and voltage control of active distribution networks. Chapter provide an overview of the active distribution network concept, present key approaches for the congestion management of active distribution networks, and cover approaches in uncertainty, coordination of DLMP, scheduled re-profiling, and more. Other sections cover real-time congestion management and service restoration of active distribution networks.

  • Bone Cell Biomechanics, Mechanobiology and Bone Diseases

    • 1st Edition
    • Ai-Rong Qian + 1 more
    • English
    Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students.

  • Diffusion of Innovative Energy Services

    Consumers’ Acceptance and Willingness to Pay
    • 1st Edition
    • Anna Kowalska-Pyzalska
    • English
    Diffusion of Innovative Energy Services: Consumers’ Acceptance and Willingness to Pay consolidates research in the diffusion, adoption and acceptance of Innovative energy services (IES), including dynamic green electricity tariffs, small-scale energy generators, and smart metering information systems among residential electricity consumers. The book addresses consumer awareness, acceptance and engagement towards smart technologies, focusing on the ‘willingness to pay’ for IES. Chapters address findings from field experiments, pilot programs and simulation methods such as agent-based modeling. Case studies involve various countries and continents, with a focus on modern, pro-environmental and sustainable economies, where IES are offered. Policy recommendations, tools and interventions as well as behavioral strategies conclude the work.

  • Advances in Computers

    • 1st Edition
    • Volume 131
    • Ali Hurson
    • English
    Advances in Computers, Volume 131 is an eclectic volume inspired by recent issues of interest in research and development in computer science and computer engineering. Chapters in this new release include eHealth: enabling technologies, opportunities, and challenges, A Perspective on Cancer Data Management using Blockchain: Progress and Challenges, Cyber Risks on IoT Platforms and Zero Trust Solutions, A Lightweight Fingerprint Liveness Detection Method for Fingerprint Authentication System, and Collaborating Fog/Edge Computing with Industry 4.0 – Architecture, Challenges and Benefits, Raspberry Pi-s for Enterprise Cybersecurity Applications.

  • Artificial Intelligence

    • 1st Edition
    • Volume 49
    • English
    Artificial Intelligence, Volume 49 in the Handbook of Statistics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Chapters in this new release include AI Teacher-Student based Adaptive Structural Deep Learning Model and Its Estimating Uncertainty of Image Data, Machine-derived Intelligence: Computations Beyond the Null Hypothesis, Object oriented basis of artificial intelligence methodologies I in Judicial Systems in India, Artificial Intelligence in Systems Biology, Machine-Learning in Geometry and Physics, Innovation and Machine Learning: Crowdsourcing Open-Source Natural Language Processing (NLP) Algorithms to Advance Public Health Surveillance, and more. Other chapters cover Learning and identity testing of Markov chains, Data privacy for machine learning and statistics, and The interface between AI and Mathematics.

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