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Academic Press

  • Phospholipases in Physiology and Pathology

    • 1st Edition
    • Sajal Chakraborti
    • English
    Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases.

  • Handbook of Child and Adolescent Psychology Treatment Modules

    Personalized Care in Behavior and Emotion
    • 1st Edition
    • Lara Jean Farrell + 2 more
    • English
    Handbook of Child and Adolescent Psychology Treatment Modules: Personalized Care in Behavior and Emotion provides clinicians with modularized treatment strategies for commonly occurring child and youth mental health disorders. Divided into two sections, the first part of the book translates basic science into clinical practice, reviewing predictors, mediators and moderators of change, and an overview of evidence for best practices in treating disorders. The second section guides clinicians on how to implement treatment strategies. Chapters instruct what therapy is, how to introduce it to clients, step-by-step implementation, worksheets for use in practice, homework to send home with clients, and more.

  • Coherent Electron Microscopy: Designing Faster and Brighter Electron Sources

    • 1st Edition
    • Volume 227
    • Peter W. Hawkes + 1 more
    • English
    Coherent Electron Microscopy: Designing Faster and Brighter Electron Sources, Volume 227 in the Advances in Imaging and Electron Physics series, merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. Chapters in this new release cover Characterization of nanomaterials properties using FE-TEM, Cold field-emission electron sources: From higher brightness to ultrafast beams, Every electron counts: Towards the development of aberration optimized and aberration corrected electron sources, and more. The series features articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science, digital image processing, electromagnetic wave propagation, electron microscopy and the computing methods used in all these domains.

  • The Transgender Athlete

    A Guide for Sports Medicine Providers
    • 1st Edition
    • Amy M. West
    • English
    The Transgender Athlete: A Guide for Sports Medicine Providers presents sports medicine practitioners insights into the unique issues and concerns of transgender athletes in order to help them understand rules regarding transgender athlete participation and learn how to better provide competent care to transgender athletes. There are over 1.4 million transgender adults in the United States. Transgender individuals undergo gender-affirming treatments including sex hormone therapy and gender-affirming surgery. An increasing number of transgender people are participating in sports and presenting to sports medicine clinics with injuries, yet there is little research about this athlete population. It is important that sports medicine providers understand the types of hormone treatments and surgeries and how these changes affect the musculoskeletal health of transgender people. Additionally, transgender people may require specific considerations when interacting with medical providers. Furthermore, sports medicine providers are often consulted to formulate transgender athlete inclusion policy. These policies are continuously changing, as new evidence becomes available, which may be difficult to understand without knowledge of the gender transition process.

  • Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

    • 2nd Edition
    • Sorin Hostiuc
    • English
    **Selected for 2025 Doody’s Core Titles® in Medical Ethics**The Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy. This second edition of Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers a thorough, timely discussion of ethical issues raised by the latest genetic and genomic technologies applied in human reproductive and prenatal medicine, providing practical recommendations, guidelines, and algorithms to support ethical clinical practice. Here, international experts consider the ethics of technologies from preconception carrier screening to genetic engineering, CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction, and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Throughout the book, contributors adopt a global, holistic perspective on applied challenges and the moral questions around the implementation of genetic reproductive technologies. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors, and graduate and medical students.This fully updated second edition examines new developments in the field, tackling ethical aspects of organoid development, recent advances in pharmacogenomics, direct-to-consumer genetic testing, and genetic engineering.

  • Translational Sports Medicine

    • 1st Edition
    • Jeffrey A. Bakal + 3 more
    • English
    Translational Sports Medicine covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. This title is an indispensable tool in grant writing and funding efforts with its practical, straightforward approach that will help aspiring investigators navigate challenging considerations in study design and implementation. It provides valuable discussions of the critical appraisal of published studies in translational sports medicine, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or sports medicine clinician who has ever had a good clinical idea but not the knowledge of how to test it. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational sports medicine, and know what is needed in collaboration.

  • Surfactants in Biopharmaceutical Development

    • 1st Edition
    • Atanas V. Koulov + 1 more
    • English
    Surfactants in Biopharmaceutical Development addresses the progress, challenges, and opportunities in surfactant research in the context of the development of biologic therapeutics. It has been widely recognized that surfactants provide protection to therapeutic proteins against interfacial stresses, which is the reason that nearly all therapeutic proteins in development and on the market today contain surfactants. Despite the fact that the very mechanism of protein stabilization by surfactants has not been completely understood, surfactants are universally regarded as critical functional excipients for biopharmaceuticals by the industry and by regulators.This book provides a broad range of important surfactant-related topics as they relate directly to biopharmaceutical development. The initial chapters of the book address fundamental topics, like synthesis of surfactants, mechanisms of protein stabilization by surfactants, as well as practical considerations for the use of surfactants in biomanufacturing. Later chapters provide overview of the state-of-the-art analytical technology and methods for quantification and characterization of surfactants, as well as a deep-dive in one of the hottest topics in biopharmaceutical development today – surfactant degradation and its impact to drug product quality and stability. The book concludes with forward-looking chapters on control strategies with a special focus on current regulatory aspects of paramount importance for biopharmaceutical companies and regulators.

  • Heat Exchange of Tubular Surfaces in a Bubbling Fluidized Bed

    • 1st Edition
    • Oleksandr Redko + 1 more
    • English
    Heat Exchange of Tubular Surfaces in a Bubbling Boiling Bed bridges the gap surrounding the study of a boiling bed of large particles with smooth and ribbed pipes, as well as pipe bundles. The book's authors combine results from experimental studies with their varied practical experience in fields of boiling bed applications across various disciplines such as chemical, pharmacological, metallurgical and power engineering industries. This book provides readers with a deep practical understanding of how to calculate the heat engineering parameters of ribbed pipe bundles in a boiling bed, along with the hydrodynamics of the boiling bed.Researchers and experts involved in the design, development and operation of boiling bed apparatus will follow step-by-step methods and procedures to gain knowledge of the hydrodynamic and heat exchange elements of the boiling bed which can be applied to their own settings. The effect of gas velocity, size and properties of the dispersed material, the geometric characteristics of the pipe bundle is also presented, alongside data on the effect of high temperature and high pressure of gas in a dispersed system on heat exchange intensity.

  • QSAR in Safety Evaluation and Risk Assessment

    • 1st Edition
    • Huixiao Hong
    • English
    QSAR in Safety Evaluation and Risk Assessment provides comprehensive coverage on QSAR methods, tools, data sources, and models focusing on applications in products safety evaluation and chemicals risk assessment.Organized into five parts, the book covers almost all aspects of QSAR modeling and application. Topics in the book include methods of QSAR, from both scientific and regulatory viewpoints; data sources available for facilitating QSAR models development; software tools for QSAR development; and QSAR models developed for assisting safety evaluation and risk assessment. Chapter contributors are authored by a lineup of active scientists in this field. The chapters not only provide professional level technical summarizations but also cover introductory descriptions for all aspects of QSAR for safety evaluation and risk assessment.

  • Unmanned Aerial Systems in Agriculture

    Eyes Above Fields
    • 1st Edition
    • Dionysis Bochtis + 2 more
    • English
    Unmanned Aerial Systems in Agriculture: Eyes Above Fields bridges the gap between knowledge of concept and real-world use and operations of UASs in agri-production. Based on a valuable combination of themes presented at the 13th European Federation for Information Technology in Agriculture, Food and the Environment (EFITA) and supplemented by targeted invited articles of key-scientists, this book presents a full-spectrum view of the use of unmanned aerial systems (UAS) for agricultural applications. It integrates dispersed knowledge in the field, providing a holistic approach regarding UAVs and other UAS and their use in sustainable decisions. The integrated approach of the book provides a fresh look on contemporary agriculture-related issues, following precision farming approaches, by educating on a range of different issues of remote sensing and its use in agriculture. Furthermore, the operational planning aspects for UAS in agriculture focus part of the book provides information that is missing from other resources.

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