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Elsevier

Academic Press

  • Replacement Therapies in Adrenal Insufficiency

    • 1st Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Replacement Therapies in Adrenal Insufficiency provides a thorough understanding of the conditions which result in adrenal insufficiency. Never before has one source of information combined all updates on current causes and mechanisms of adrenal sufficiency to allow for quick reference and subsequent treatment decisions. Scientific data on this broad condition includes specific disease coverage of Addison’s disease, hypopituitarism, congenital adrenal hypoplasia and adrenalectomy. Practical points in diagnosis, dosing, drug interactions, replacement therapies and emergency situations are also provided as guidance for overall management.

  • Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds

    From Laboratory to Industry
    • 1st Edition
    • Yongjun Wei + 2 more
    • English
    Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limits their application in drugs and other industries. While the biosynthesis of some complex bioactive compounds is possible, the scale-up and chemical process technology still needs further application in commercial production of the plant-derived bioactive compounds.Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds: From Laboratory to Industry summarizes recent commercial microbial production strategies for plant-derived bioactive compounds. This comprehensive summary will be of great interest to scientists and researchers, as well as engineers who work on the microbial production of plant-derived bioactive compounds in the industry.

  • Functional Foods and Chronic Disease

    Role of Sensory, Chemistry and Nutrition
    • 1st Edition
    • Michel Aliani + 1 more
    • English
    Functional Foods and Chronic Disease: Role of Sensory, Chemistry and Nutrition explores the range of functional foods that are effective against a wide range of chronic diseases and addresses the impact of functional food bioactive compounds on organoleptic properties. Beginning with an introduction that details the key sensory and advanced instrumental methods essential for addressing the common problems associated with designing functional foods, the book also addresses the impact of aging and chronic diseases on sensory acuity as well as the effectiveness of functional foods in treating a wide range of chronic diseases. Sections highlight the need for acceptable functional foods for individuals suffering from a wide range of chronic diseases and contain practical recommendations for their development. Food scientists, nutritionists, dietitians, food product developers, food supplement producers, food ingredient developers, natural product scientists, herbalists, and pharmacists, as well as students studying related areas, will benefit from this important resource.

  • Enhancement of Brain Functions Prompted by Physical Activity Vol 1

    • 1st Edition
    • Volume 283
    • English
    The goal for this special edition of Progress in Brain Research extends beyond merely probing the yet-to-be-uncovered links between physical exercise and cognitive improvement. We aim to advance our knowledge, pushing the envelope of what is currently understood. We are particularly focused on how purposefully structured physical activities, carefully chosen participant groups, and specific cognitive areas can optimize the cognitive and mental health benefits derived from physical exercise. The inaugural volume of this series introduces 3 review articles and 7 original pieces of research, encompassing both behavioral experiments and neuroimaging studies. Our focus is on experimental research that sheds light on the immediate and long-term impact of physical exercise on cognition as well as expert opinions and systematic reviews that compile current findings and suggest avenues for upcoming research.

  • Encyclopedia of Fish Physiology

    • 2nd Edition
    • Sarah L. Alderman + 1 more
    • English
    Encyclopedia of Fish Physiology, Second Edition is a comprehensive, introductory-level reference work that aims to unite readers in the wonders of this discipline. Chapters highlight where physiological systems and processes are conserved across vertebrate groups, which supports the use of fish as a vertebrate model for investigating fundamental problems in physiology and knowledge transfer to the medical field. Other chapters highlight unique specializations and adaptations that allow fish to survive in challenging environments, leading to a deeper appreciation of the natural world. Final sections demonstrate the consequences of perturbing physiological systems and how this knowledge can empower conservation strategies to protect fish. Much has changed in the field of fish physiology since publication of the previous, Prose award winning, edition. For example, we understand better the impacts of global climate change on the physiological systems of fish, and we have gained a deeper mechanistic understanding of physiological processes through technological advancements such as gene editing with CRISPR, whole genome sequencing, and quantitative ‘omic` approaches. The new edition greatly expands the closing thematic section focused on applying fish physiology to real world challenges with topics including ocean acidification, declining habitat quality due to human activities, and the use of zebrafish in biomedical studies on tissue regeneration, neurological disorders and cancer.

  • CRISPRized Horticulture Crops

    Genome Modified Plants and Microbes in Food and Agriculture
    • 1st Edition
    • Kamel A. Abd-Elsalam + 2 more
    • English
    CRISPRized Horticultural Crops: Genome Modified Plants and Microbes in Food and Agriculture summarizes applications of CRISPR/Cas systems and its advanced variants e.g., CRISPR/Cpf1, base editing and prime editing, for precise editing of horticultural crops. The book discusses vector transformations methods, epi-genome, deep learning, synthetic biology, and precision breeding for improving yield and quality related attributes in horticultural crops. With coverage of the relevant technologies and their applications, the book also includes bioinformatics and large-scale databases and their potential application in fruits, vegetables and ornamental plants and sections on regulatory concerns related to CRISPR edited crops. Horticultural crops, including fruit, vegetable and ornamental plants are an important component of agriculture production systems and play an important role in sustaining human life.

  • Beneficial Microbes for Sustainable Agriculture under Stress Conditions

    Functional Traits and Regulation
    • 1st Edition
    • Tongmin Sa
    • English
    Beneficial Microbes for Sustainable Agriculture under Abiotic Stress: Functional Traits and Regulation highlights the potential for microbe-mediated stress phytotolerance to be improved by presenting multiple scenarios of application and results.In most research and studies, abiotic stress is applied singularly to specific plants inoculated with a bioinoculum or a microbial consortium to isolate specific plant-microbe responses. However, in reality, plants are continually exposed to a multitude of different stresses simultaneously occurring. This book presents microbial functional traits and microbe-mediated plant responses under both specific or combined stress conditions. Collectively, it provides insights into microbial functional traits and microbe-mediated plant responses in a wide range of conditions, providing foundational understanding of their potential benefits, and inspiring further research.The book also centers on specific microbial strains and groups which have been shown to effectively promote stress tolerance, and which could be utilized to boost agricultural production under stress conditions. Their potential utilization in stress affected lands not just improves crop production but could also be in line with sustainable agriculture.With the advancement of tools such as omics related technologies, emerging information on microbial functional traits and regulations on microbe-mediated phytotolerance will also allow us to develop relevant biotechnologies harnessing potentials of plant-microbe interactions under stress conditions. The information in this volume will be of interest to those working toward these next steps.

  • Nanotoxicology for Agricultural and Environmental Applications

    • 1st Edition
    • Mahendra Rai + 1 more
    • English
    Nanotoxicology for Agricultural and Environmental Applications provides an introduction to nanotechnology and its applications in agriculture and the environment. This reference, especially focused on the role of each physicochemical property of nanomaterials in toxicity, also presents a consolidated discussion on the management of the risks associated with nanoparticle use and rules and regulations made by various countries and organizations around the world.Structured into five parts, this book explores nanotoxicity concerning agriculture and food, its impact on the environment, risk management measures for avoiding exposure, and delves into the realm of nanotechnology regulations. Students, practitioners, and researchers working in plant science, agricultural science, nanoscience, and environmental chemistry alike will benefit from this necessary reference.

  • Myeloid-Derived Suppressor Cells

    • 1st Edition
    • Volume 184
    • English
    Myeloid-Derived Suppressor Cells, Volume 184 in the Methods in Cell Biology series includes comprehensive protocols to assess the role of myeloid-derived suppressor cells (MDSCs), an immature, heterogenous cell population from the myeloid lineage with a potent immunosuppressive activity in a variety of diseases. This volume includes interesting protocols that address the Detection of myeloid-derived suppressor cells by flow cytometry, Determination of murine myeloid-derived suppressor cells by flow cytometry, Isolation of Myeloid-Derived Suppressor Cells (MDSC) from Endometriotic Mice Model and their Immunomodulatory Functions, Simple protocol for measuring CD11b+ GR-1+ (Ly6C+/Ly6G+) myeloid cells from a minimum volume of mouse peripheral blood, and much more.Additional chapters cover Assessment of myeloid-derived suppressor cell differentiation ex vivo, Single clonal tracking on biomimetic microtextured platforms for real-time guided migration analysis of myeloid-derived suppressor cell dissemination characteristics ex vivo, Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes, Characterization of lysosomal acid lipase in Ly6G+ and CD11c+ myeloid-derived suppressor cells, In Vitro Osteoclastogenesis Assessment using Murine Myeloid-derived Suppressor Cells, Estimating Nitric Oxide (NO) from MDSCs by Griess Method, and In vitro generation of myeloid-derived suppressor cells (MDSCs) from hematopoietic progenitor cells (HPCs).

  • Modern Inference Based on Health-Related Markers

    Biomarkers and Statistical Decision Making
    • 1st Edition
    • Albert Vexler + 2 more
    • English
    Modern Inference Based on Health Related Markers: Biomarkers and Statistical Decision Making provides a compendium of biomarkers based methodologies for respective health related fields and health related marker-specific biostatistical techniques. The book introduces correct and efficient testing mechanisms, including procedures based on bootstrap and permutation methods with the aim of making these techniques assessable to practical researchers. In the biostatistical aspect, it describes how to correctly state testing problems, but it also includes novel results, which have appeared in current statistical publications.In addition, the book discusses also modern applied statistical developments that consider data-driven techniques, including empirical likelihood methods and other simple and efficient methods to derive statistical tools for use in health related studies.

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