
Neonatal Intensive Care for Extremely Preterm Infants
Japanese NICU Practices to Prevent Mortality and Morbidities
- 1st Edition - September 19, 2024
- Imprint: Academic Press
- Editors: Satoshi Kusuda, Hidehiko Nakanishi, Tetsuya Isayama
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 7 3 1 0 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 7 3 1 1 - 7
Neonatal Intensive Care for Extremely Preterm Infants: Japanese NICU Practices to Prevent Mortality and Morbidities presents the latest updates from top Japanese researchers at top… Read more

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Request a sales quoteNeonatal Intensive Care for Extremely Preterm Infants: Japanese NICU Practices to Prevent Mortality and Morbidities presents the latest updates from top Japanese researchers at top Japanese institutions who come together to share their knowledge and implementation strategies globally. Utilizing the same drugs and devices found in NICUs worldwide, this title reviews how Japanese NICUs use them most effectively to improve outcomes in highest-risk infants.
Chapters cover resuscitation and respiratory care, circulatory support, neurological care, fluid management, nutrition support, and infection control. Final chapters are devoted to sharing details of the Japanese NICU clinical environment as well as best practices for extremely preterm infant follow-up after NICU discharge. Researchers and clinicians worldwide will find this title to be an invaluable resource in improving outcomes for this most vulnerable population.
Chapters cover resuscitation and respiratory care, circulatory support, neurological care, fluid management, nutrition support, and infection control. Final chapters are devoted to sharing details of the Japanese NICU clinical environment as well as best practices for extremely preterm infant follow-up after NICU discharge. Researchers and clinicians worldwide will find this title to be an invaluable resource in improving outcomes for this most vulnerable population.
- Reviews Japanese intensive care best practices for extremely preterm infants
- Provides knowledge and guidance by top Japanese researchers from top institutions with the best outcomes in neonatal intensive care
- Offers strategies to prevent mortality and morbidities and improve patient outcomes
Scientific researchers, healthcare providers, and medical students of Neonatology, Pediatrics, and Obstetrics Parents of preterm infants
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Acknowledgments
- Chapter 1. Perinatal healthcare system
- 1.1. Perinatal healthcare system and its regionalization
- 1.2. Maternal and neonatal transport
- 1.3. Maternal and Child Health Handbook and medical check-ups for pregnant women
- 1.4. Health insurance system
- 1.5. Cost for NICU stay
- 1.6. Limit of viability and ethical issues
- Chapter 2. Physiology of extremely preterm infants
- 2.1. Terminology
- 2.2. Organ physiology of extremely preterm infants
- 2.3. Definition of live birth and limit of viability
- Chapter 3. Resuscitation
- 3.1. Prenatal counseling
- 3.2. Delivery room management
- 3.3. Placental transfusion
- 3.4. Target SpO2 and oxygen concentration
- Chapter 4. Respiratory care
- 4.1. Diagnosis
- 4.2. Monitoring and evaluation
- 4.3. Surfactant installation
- 4.4. Mechanical ventilation
- 4.5. High-frequency oscillatory ventilation (HFOV) management
- 4.6. Noninvasive respiratory support
- 4.7. Persistent pulmonary hypertension of the newborn (PPHN) management
- Chapter 5. Respiratory care for chronic lung disease
- 5.1. Diagnosis and classification
- 5.2. Prevention of CLD
- 5.3. Glucocorticoid use
- 5.4. General support
- Chapter 6. Circulatory support
- 6.1. General support
- 6.2. Echocardiography
- 6.3. Monitoring and evaluation (blood pressure, perfusion)
- 6.4. Volume expander
- 6.5. Pharmacological support
- 6.6. Management of anemia
- Chapter 7. Patent ductus arteriosus
- 7.1. Diagnosis
- 7.2. Prophylaxis
- 7.3. Pharmacological treatment
- 7.4. Surgical intervention
- 7.5. Device closure
- Chapter 8. Neurological diseases
- 8.1. Neuroimagings: Cranial ultrasound and brain MRI
- 8.2. Intraventricular hemorrhage and posthemorrhagic hydrocephalus
- 8.3. Periventricular leukomalacia
- Chapter 9. Fluid management
- 9.1. General management
- 9.2. Thermal and humidity support and fluid balance
- 9.3. Electrolyte and mineral control during fluid therapy
- 9.4. Hemodialysis
- Chapter 10. Nutritional support
- 10.1. Nutrition, growth, and requirements
- 10.2. Venous nutrition
- 10.3. Enteral feeding and use of breast milk
- 10.4. Probiotics
- 10.5. Diagnosis and management of necrotizing enterocolitis
- 10.6. Diagnosis and management of meconium-related ileus
- Chapter 11. Infection control
- 11.1. Diagnosis and general management
- 11.2. Bacterial infection and fungal infection
- 11.3. Viral infection and others
- Chapter 12. Working environment
- 12.1. Characteristics of perinatal medical center in Japan
- 12.2. Day-to-day management responsibilities
- 12.3. Overtime work of neonatal physicians
- Chapter 13. Nursing care
- 13.1. Minimal handling
- 13.2. Skincare
- 13.3. Glycerin enemas
- 13.4. Positioning
- 13.5. Pain management
- 13.6. Family involvement
- Chapter 14. Follow-up
- 14.1. System
- 14.2. Current outcomes from the NRNJ database [2003–17]
- Appendix 1: Birth weight reference
- Appendix 2: Postnatal growth
- Appendix 3: Clinical data references by gestational age
- Appendix 4: Drug Doses
- Index
- Edition: 1
- Published: September 19, 2024
- Imprint: Academic Press
- No. of pages: 290
- Language: English
- Paperback ISBN: 9780443273100
- eBook ISBN: 9780443273117
SK
Satoshi Kusuda
Satoshi Kusuda, MD, PhD is the director of the Neonatal Research Network of Japan (NRNJ). He graduated from medical school in Osaka, Osaka City University. After completing his residency in pediatrics, he started specialty training at Children’s Hospital in Osaka City and completed his internship at Osaka City General Hospital in neonatology. He has more than 30 years' experience working in NICUs. He is a Board member of the Japanese Society for Perinatal and Neonatal Medicine. His primary research interests include network databases and neonatal respiratory care. Today, the number of very preterm infants registered on the NRNJ database has increased to over 80 thousand and Dr. Kusuda has published more than 150 papers in peer-reviewed journals.
Affiliations and expertise
Director, Neonatal Research Network of Japan, JapanHN
Hidehiko Nakanishi
Hidehiko Nakanishi, MD, PhD is the Professor, Research and Development Center for New Medical Frontiers, Department of Advanced Medicine, Division of Neonatal Intensive Care Medicine, Kitasato University School of Medicine. After graduating Osaka City University Medical School, he started his residency at Osaka City General Hospital as a pediatrician then specialized in neonatology at the same hospital. In 2005, he moved to Anesthesia & Critical Care, Massachusetts General Hospital as a research fellow. Four years later, he moved to Tokyo Women’s Medical University to continue his specialty as a neonatologist and further his research on pulmonary physiology in infants. He became a Professor at Kitasato University in 2018. He has published 29 articles in international journals. He currently serves on the board of directors of the Japan Society for Neonatal Health and Development, the Japan Society of Perinatal and Neonatal Medicine, and the Neonatal Research Network of Japan.
Affiliations and expertise
Professor, Research and Development Center for New Medical Frontiers, Department of Advanced Medicine, Division of Neonatal Intensive Care Medicine, Kitasato University School of Medicine, Minamiku, Sagamihara, Kanagawa, JapanTI
Tetsuya Isayama
Tetsuya Isayama, MD, MSc, PhD is Head of the Division of Neonatology, National Center for Child Health and Development. He is a graduate of Graduate School of Science, Kyoto University and Kyoto Prefectural University of Medicine, where he started his pediatric residency. Later he completed a 3-year fellowship at Osaka Women’s and Children’s Hospital, a neonatal fellowship at the University of Toronto, and a clinical fellowship at Sunnybrook Health Science Center. While in Toronto, he obtained a PhD from McMaster University in clinical epidemiology and in 2017 became the Head of Neonatal Division. He has published over 80 articles in international journals and 5 international guidelines for neonatal care. He is currently Emeritus Task Force of the Neonatal Life Support of ILCOR, Director of AsianNeo, on the Board of Directors of the NRNJ, the Japan Society for Neonatal Health and Development, and the Japan Society of Perinatal and Neonatal Medicine.
Affiliations and expertise
Head of the Division of Neonatology, National Center for Child Health and Development (NCCHD), Setagaya, Tokyo, JapanRead Neonatal Intensive Care for Extremely Preterm Infants on ScienceDirect