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Elsevier

Academic Press

  • Advances in Immunology

    • 1st Edition
    • Volume 163
    • English
    Advances in Immunology, Volume 163, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample chapters include The role of autophagy in RIP1 mediated cell death and intestinal inflammation, IL-17 family cytokines in inflammatory or autoimmune kin diseases, and more.​​​​​​

  • CRISPR-Cas-Based Genome Editing for Treating Human Diseases-Part A

    • 1st Edition
    • Volume 208
    • English
    CRISPR-Cas-Based Genome Editing for Treating Human Diseases-Part A, Volume 208 represents CRISPR-Cas systems for genome editing. Currently, CRISPR-Cas systems are proven a key technology for targeted genome editing, which is acting as a simple, rapid, and cost-effective solution. CRISPR-Cas9 system is being used in microbial genome editing, mammalian genome editing, disease models, and more. It has shown potential in human disease treatment. However, it is not easy to find CRISPR-Cas systems genome editing in a single source.This volume offers CRISPR-Cas systems for human diseases, bacterial disease, gut microbiome editing, viral disease, protozoan disease, fungal disease, stem cell therapy, CRISPR in epigenetics, CRISPR in cancer, autoimmune and blood disorders. In addition, it highlights a number of aspects of the CRISPR-Cas systems that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

  • Zinc in Plants

    Current Knowledge and Recent Advances
    • 1st Edition
    • Durgesh Kumar Tripathi + 4 more
    • English
    Zinc in Plants: Current Knowledge and Recent Advances addresses zinc hunger, the transport of zinc in the soil-plant interphase, zinc and abiotic stress in plants, and zinc and plant disease. Written by experts in the field, this title is an essential resource to all scientists and students interested in plant physiology, biochemistry and agriculture. During their life, plants encounter various challenges, including their normal development under changing environmental conditions. Zinc (Zn) is an essential component of thousands of proteins in plants, although it is toxic in excess, and is essential for many processes throughout the plant lifecycle.

  • Medical and Educational Needs for Autism

    • 1st Edition
    • Michelle Hartley-McAndrew + 1 more
    • English
    Medical and Educational Needs for Autism aims to provide understanding and assistance to clinicians interacting with ASD patients and their caregivers. This book is divided into two clear sections, first the medical coverage and second, an educational section. The first section includes chapters on sleep disorders, feeding/nutrition concerns, and medication. The second section focuses on the education component which includes IEP processes and activities for daily living.

  • Fundamentals of Recombinant Protein Production, Purification and Characterization

    • 1st Edition
    • Deepti Yadav + 2 more
    • English
    Fundamentals of Recombinant Protein Production, Purification and Characterization is organized into nine chapters in a logical fashion that cover an introduction to recombinant proteins and expression in different host expression systems, extraction, purification and analysis of proteins. This important reference features protocols, along with the advantages and disadvantage of each expression hosts and characterization technique (presented in tabular format) and offers detailed coverage of all aspects of protein production and processing (upstream and downstream processing) in one place. Finally, the book ends with different characterization techniques. Production of recombinant proteins for biotechnological and therapeutic applications at a large scale is an essential need of mankind. With the huge application potential of therapeutic and industrial proteins, there has been increasing demand for effective and efficient bioprocessing strategies. Recent progress around recombinant DNA technologies and bioprocessing strategies has paved the way for efficient production of recombinant proteins. Important factors such as insolubility and cost of production need to be considered for large scale production of these recombinant proteins.

  • Understanding Autism

    Perspectives, Assessment, Interventions, and the Journey Towards Inclusion
    • 1st Edition
    • Neophytos L. Papaneophytou + 1 more
    • English
    Understanding Autism: Perspectives, Assessment, Interventions, and the Journey Toward Inclusion is a compelling book offering a multifaceted examination, providing readers with a comprehensive understanding of autism spectrum disorder from both biological and social perspectives. From the role of bioactive lipids in the pathobiology of autism to the challenges faced by individuals with autism within the criminal justice system, this book explores critical aspects of autism, assessment strategies, and innovative interventions. From a biological perspective, readers will be introduced to the gut-brain connection and the impact of vitamin D on the gut microbiota. Meanwhile, the social perspective sheds light on sensory processing, autonomic regulation, and socio-emotional development in autism, as well as the pressing issue of justice and representation. Through the assessment section, readers will explore the unique challenges faced by parents with autism spectrum disorder and delve into linguistic anomalies in autism. Finally, the interventions section introduces groundbreaking programs and strategies designed to improve the lives of individuals with autism. Whether you’re a healthcare professional, educator, or simply curious about autism, this book is an essential guide that offers diverse insights into this complex condition, ultimately fostering greater awareness, understanding, and support for individuals on the spectrum.

  • mRNA Therapeutics

    Foundations, Innovations, and Clinical Applications
    • 1st Edition
    • Anya Hillery
    • English
    mRNA Therapeutics: Foundations, Innovations and Clinical Applications aims to provide a comprehensive text that covers all aspects of mRNA therapeutics, from the foundational science that underpins this disruptive new drug class, through the scientific and technological breakthroughs crucial for therapeutic success, to the current clinical applications and the innovative advances driving future directions. The book begins with foundational knowledge covering mRNA biology, the immune system, and vaccines. The second section addresses the major challenges associated with mRNA as a therapeutic modality, and the molecular engineering innovations and delivery technologies that have allowed these hurdles to be largely overcome. The third section describes the current and future clinical applications of mRNA therapeutics that are transforming, or are poised to transform, medicine and health. This includes the use of mRNA vaccines for COVID-19 and other infectious diseases, as well as mRNA's role in revolutionizing cancer immunotherapy, covering immunostimulants, cancer vaccines including personalized neoantigen vaccines, and CAR T cell technologies. Additional chapters describe the use of mRNA therapeutics for protein replacement therapy and gene-editing, as well as newer mRNA constructs, including self-amplifying mRNA. The final section addresses the safety and regulatory considerations of mRNA therapeutics, along with broader cultural issues including vaccine hesitancy, global vaccine inequality, and pandemic preparedness. Currently, mRNA texts either provide personal accounts from key players involved in COVID-19 vaccine development, with limited scientific depth, or focus on highly specialized, more esoteric applications of mRNA in advanced molecular biology. This book aims to bridge this gap by providing a scientifically rigorous and wide-ranging exploration of mRNA's role in therapeutics. This pioneering textbook serves as a vital addition to the academic canon, providing an essential tool for the current and next generation of students, scientists, researchers and professionals in a wide variety of related disciplines including molecular biology, biomedical engineering, pharmaceutical science, oncology, and the health sciences.

  • Advances in Child Development and Behavior

    • 1st Edition
    • Volume 67
    • English
    Advances in Child Development and Behavior, Volume 67, the latest release in this classic resource on the field of developmental psychology, includes a variety of timely updates, with this new volume presenting interesting chapters on topics such as Conceptual and Empirical Advances in Afterschool Research, Unraveling the Transracial Adoption Paradox: Construction race and racism in adoptive families, Risk and Resilience Models in Child Development, The Dual Journey: The Development of Twins’ Relationships Throughout Childhood, A sociocultural perspective of multimodal learning by infants and young children, and Defining the Role of Executive Function in Children's Sociomoral Reasoning.

  • Fundamentals of Soft Interfaces in Colloid and Surface Chemistry

    • 1st Edition
    • Volume 37
    • Hiroyuki Ohshima
    • English
    This book explains and summarizes the fundamentals of soft interfaces and soft particles from a colloid and surface chemistry standpoint, bringing knowledge together into a single resource for the first time. It provides detailed mathematical description of colloidal and interfacial systems, with a particular emphasis on ionic, electrokinetic, and electrostatic phenomena. Hiroyuki Ohshima covers the most recent theoretical advances in the field of electrostatic interactions between soft interfaces, electrophoresis, diffusiophoresis, gel electrophoresis of soft particles including ionic size effects, ion-partitioning effects, and the effects of hydrodynamic slip on hydrophobic surfaces. It will help readers by providing a range of approximate analytic formulas which can be used to interpret various interfacial phenomena of soft interfaces and analyze experimental data in various fields. Fundamentals of Soft Interfaces in Colloid and Surface Chemistry is written for graduate students and researchers chiefly in chemistry but also chemical engineering, physics, and materials science.

  • Training Human Service Staff

    Evidence-Based Strategies for Promoting Effectiveness, Efficiency, and Trainee Acceptance
    • 1st Edition
    • Dennis H. Reid + 1 more
    • English
    Training Human Service Staff: Evidence-Based Strategies for Promoting Effectiveness, Efficiency, and Trainee Acceptance is a comprehensive guide that equips professionals with the tools and techniques to optimize the training of human service staff. In Section I, readers are introduced to staff training, understanding its importance and the critical criteria for success. The book delves into the gold standard of Behavioral Skills Training and explores in-person training methodologies in Section II, which encompass both group and individual staff training.Section III reviews technology-based training, including video modeling, computer-based training, and distance training via telehealth, offering readers innovative approaches to meet modern training demands. Special topics in staff training, such as maintaining staff skills, professional workshops, and the evolving gold standard, are explored in Section IV, rounding out a comprehensive resource.

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