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On Epigenetics and Evolution
- 1st Edition - June 25, 2024
- Editor: Carlos M. Guerrero-Bosagna
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 0 5 1 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 0 5 2 - 0
On Epigenetics and Evolution, a new volume in the Translational Epigenetics series, introduces key themes from current epigenetic evolution research, with contributions fr… Read more
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Request a sales quoteOn Epigenetics and Evolution, a new volume in the Translational Epigenetics series, introduces key themes from current epigenetic evolution research, with contributions from leading scientists around the world that investigate the role of epigenetic mechanisms in evolution from a variety of different angles, with each contribution combining theory, current research overviews, and applications. This book gives researchers, students, and clinicians a better understanding of the origin of genotypic and phenotypic variability, the role of epigenetics in development and inheritance, how epigenetics may affect speciation, and the evolution of epigenetic mechanisms in different taxa, and helps them apply their learnings across new research. Other modalities and subtopics explored include epigenetics in neutral and also adaptive evolution; epigenetic evolution in plants, invertebrates, and vertebrates; and the role of epigenetics in human evolution and its societal impact.
- Introduces and examines the role of epigenetic modifications in regulating genomic variability, and thus evolutionary biology, across species
- Draws together key themes across epigenetic evolution in plants, invertebrates, and vertebrates, and the role of epigenetics in human evolution
- Includes bulleted chapter summaries and key points lists, terms and definitions, and rich use of illustrations where possible to reinforce understanding and actionability of the content
- Features chapter contributions from international leaders in the field
Researchers and students in genetics, genomics, molecular biology, developmental biology, evolutionary biology, pharmaceutical science, nutrition, toxicology, physiology, and clinical therapy, Clinicians
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter 1. Epigenetics in evolution: State-of-the-art and future perspectives (Introductory chapter)
- Introduction
- A brief historical perspective on epigenetics
- Conceptual influences of epigenetics on evolutionary theories
- Epigenetics and speciation
- Challenges and future developments
- Chapter 2. The epigenetic system, evo-devo, and the Extended Evolutionary Synthesis
- Introduction
- A systems view of epigenetics
- Epigenetics in the Extended Evolutionary Synthesis
- Further implications
- Chapter 3. Epigenetics as a driver of adaptive evolution
- Introduction
- Ability of epigenetic mechanisms to produce phenotypic diversity
- Epigenetic variation and associated phenotypic variation in natural populations
- Autonomy of epigenetic variation from genetic variation
- Stability, selectability, and fitness effects of epimutations and corresponding phenotypes
- Transgenerational inheritance and genetic integration of epimutations and related phenotypes
- Different ways how epigenetics can contribute to adaptive evolution
- Synthesis and perspectives
- Chapter 4. Epigenetics as a mechanism for neutral and nearly neutral evolution
- Introduction
- Brief history of the neutral and the nearly neutral theories of evolution
- Epigenetics and human genome
- Genome accessibility and chromatin
- Discussion
- Chapter 5. Generational stability of epigenetic transgenerational inheritance and role of environmental epigenetics in evolutionary biology
- Modern synthesis
- Epigenetic mechanisms
- Epigenetic transgenerational inheritance
- Evolution and epigenetic transgenerational inheritance
- Generational stability of epigenetic transgenerational inheritance
- Conclusion
- Chapter 6. Epigenetics and genotypic variation: A transposable elements' perspective
- Introduction
- Studying TE epigenetics: Between challenges and breakthroughs
- TEs as a source of genotypic variation through modulation of their epigenetic control
- How does TE variation affect the epigenetic landscape?
- Evolutionary consequences of epigenetic regulation of TEs
- Conclusion
- Chapter 7. A pragmatist view of heredity: Putting epigenetics in its context
- Introduction
- The quest for inheritance
- An epistemological reformulation of inheritance
- Is pluralism justified? A meta-scientific problem
- A pragmatist view
- Conclusion
- Chapter 8. Epigenetics and the evolution and feralization of domestic animals
- Part 1: General overview
- Part 2: Case studies
- Part 3: Mechanisms
- Part 4: The synthesis
- Chapter 9. Role of epigenetic molecular mechanisms in insect evolutionary innovations
- Introduction
- Epigenetic molecular mechanisms in insects
- DNA methylation in insects
- Histone modifications in insects
- RNA epigenetics mechanisms
- Insect wings
- Insect metamorphosis
- Insect eusociality
- Pesticides and climate change effects
- Conclusions
- Chapter 10. Epigenetics in fish evolution
- Introduction
- Epigenetics in fish sex determination, differentiation, sex reversal, and sex change
- Epigenetics, adaptive diversification, and speciation
- Fish evolution under domestication from an epigenetics perspective
- Chapter 11. Evolutionary implications of epigenetic inheritance of obesity in mammals
- Introduction: 21st-century cars do not fit in old parking slots
- Obesity: A rapidly emerging phenotype
- Epigenetic mechanisms in (polygenic) obesity
- Epigenetic inheritance of obesity
- Obesity under the scope of evolution
- Experimental models to study the evolutionary implications of the epigenetic inheritance of obesity
- Conclusion
- Coda: Red cars will fly (possibly)
- Chapter 12. The evolution of epigenetic mechanisms in plants
- Introduction
- DNA methylation
- Histone modifications in plants
- Conclusion
- Chapter 13. Embodied cognition meets epigenetics: At the intersection of brain development and learning
- Introduction
- Epigenetics in cellular and cognitive memory
- Epigenetic memory in development and learning
- The molecular embodiment of spatial learning
- Learning as embodied development
- Conclusion
- Chapter 14. Responsive genome or environmental determinism?—How epigenetics resituates organism, environment, and society
- On the co-production of natural and social order
- Toward new notions of genomes and environments
- On the epigenization of mothering
- The return of the social milieu
- Race and racialization in epigenetic inquiry
- Conclusion
- Index
- No. of pages: 480
- Language: English
- Edition: 1
- Published: June 25, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443190513
- eBook ISBN: 9780443190520
CG
Carlos M. Guerrero-Bosagna
Dr. Carlos M. Guerrero-Bosagna is an Assistant Professor at the Department of Organismal Biology of Uppsala University, Uppsala, Sweden. His teaching and research demonstrate the importance of epigenetics in connecting environmental exposures and non-communicable diseases such as metabolic and reproductive disorders. His research focusses on epigenetics in different experimental models, including lab, farm animals, and humans, investigating what these tells us about epigenetics in stress response, evolution and also human diseases. He has published over 60 scientific articles to-date in peer-reviewed journals, as well as 11 book chapters, and 1 US patent application.
Affiliations and expertise
Assistant Professor at the Department of Organismal Biology of Uppsala University, Uppsala, SwedenRead On Epigenetics and Evolution on ScienceDirect